Open Access. Powered by Scholars. Published by Universities.®

Cognitive Psychology Commons

Open Access. Powered by Scholars. Published by Universities.®

Articles 1 - 2 of 2

Full-Text Articles in Cognitive Psychology

Cholesterol: A Possible Mediator Of Apoe Risk For Alzheimer's Disease, Michelle Marie Dunk Dec 2019

Cholesterol: A Possible Mediator Of Apoe Risk For Alzheimer's Disease, Michelle Marie Dunk

Theses and Dissertations

Despite the well-established link between the ε4 allele of the apolipoprotein E (APOE) gene and AD, the underlying mechanisms that mediate the risk of developing AD remain elusive. Literature on the role of APOE in cholesterol metabolism suggests that blood cholesterol may be a key factor in the development of AD pathology. Current study aims to investigate whether total cholesterol differs by APOE status and whether this relationship is predictive of AD diagnosis and its biomarkers. Baseline total cholesterol, APOE status, AD diagnosis, global cognitive function, brain Aβ, plasma Aβ40 and Aβ42, and cerebrospinal fluid (CSF) Aβ, tau, and phosphorylated …


Evaluation Of A Cognitive Training Program For Older Adults With Mild To Moderate Cognitive Decline, Kelly Bergstrom Jan 2018

Evaluation Of A Cognitive Training Program For Older Adults With Mild To Moderate Cognitive Decline, Kelly Bergstrom

All Graduate Theses, Dissertations, and Other Capstone Projects

Older adults often experience varying levels of cognitive decline. Several interventions intended to help slow the effects of cognitive decline have been studied, including cognitive training. Cognitive training involves engaging individuals, typically in a group setting, in exercises that target specific cognitive domains, such as attention, perceptual speed, memory, language, and executive functioning. Literature on cognitive training provides mixed support for its efficacy. The purpose of the current study was to determine whether a manualized, in-person cognitive training program for individuals with mild to moderate cognitive decline would lead to an improvement in cognitive performance. The program targeted six cognitive …