Cognitive Psychology Commons^™

Nutrition As A Modifiable Risk Factor For Cognitive Decline: Associated Cognitive And Physical Health Changes, Taylor Mcmillan

Electronic Theses and Dissertations

Dementia is defined as gradual, progressive loss of cognitive functioning, greater than what is expected of normal aging, resulting in functional impairment. There are several types of dementia clinical syndromes that are accompanied by unique patterns of cognitive dysfunction and neuropathological changes. Alzheimer’s disease (AD) is the most common type of clinical dementia syndrome, accounting for approximately 60-70% of cases. Neuropathological mechanisms associated with AD include the disruption of the cholinergic system, accumulation of amyloid-beta plaques and hyperphosphorylated tau, as well as vascular pathology. Vascular pathology complicates the characterization of clinical and neuropathic changes in AD, as there becomes significant …