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Full-Text Articles in Biological Psychology
The Contribution Of A Polygenic Risk Score To Individual Differences In Aggressive Behavior: The Moderating And Mediating Roles Of Stressful Events, Christa C. Christ
The Contribution Of A Polygenic Risk Score To Individual Differences In Aggressive Behavior: The Moderating And Mediating Roles Of Stressful Events, Christa C. Christ
Department of Psychology: Dissertations, Theses, and Student Research
Although aggression can be beneficial in certain situations (e.g. playing sports, self-defense), excessive and inappropriate aggression can lead to adverse physical and psychological health outcomes in both perpetrators and victims. Genetic susceptibility to negative environments can increase the likelihood of aggressive behavior in the context of situational risk factors. Low efficiency of serotonin neurotransmission and exposure to stress appear to play a prominent role in the etiology of aggressive behavior. A set of three studies assessed the contribution of polygenic risk (TPH2 rs4570625, SLC6A4 5-HTTLPR+rs25531, HTR1B rs13212041, MAOA uVNTR) to aggressive behavior, including alcohol-related aggression, in university students at varying …