Biological Psychology Commons^™

Cognitive Functioning In Well-Controlled Asthma, Erin Walsh

West Chester University Doctoral Projects

Asthma is a common lung disease that impacts lung functioning through inflammatory based mechanisms. Past research suggests that decreased blood oxygenation due to asthma attacks may impair cognitive capabilities (Irani et al., 2017). Moreover, the observed differences in cognition between those with and without asthma may be associated with disease severity or asthma control respectively in asthma populations. The current study explored differences in cognitive functioning between college students with and without self-reported asthma. Sociodemographic data, self-reported asthma severity, and measures of asthma control were collected. The current study did not find significant differences in measures of cognitive efficiency between …

Neural Correlates And Neuroanatomy Of Juvenile And Adult Contextual Fear Memory Retention, Natalie Odynocki

Legacy Theses & Dissertations (2009 - 2024)

AbstractFear is an evolutionarily conserved mechanism that allows an organism to discern potential harm and act accordingly by engaging in defensive behaviors. While fear is an adaptive response, dysregulation of fear by means of a traumatic event can lead to psychiatric conditions such as post-traumatic stress disorder (PTSD). Animal research using rodents in Pavlovian context fear conditioning experiments allows for the ability to study the underlying neural circuitry of threat-appropriate and aberrant fear learning and memory that may contribute to PTSD. However, despite reports that women are more than two times more likely to develop PTSD compared to men, the …

Investigation Of A Misophonia And Fluid Intelligence Relationship: Sound Spectrum Variation Impact On Fluid Intelligence Task Responses, Leslie Watson

Master's Theses

ABSTRACT Studies of misophonia have not assessed the impact of music and sound complexity on intelligence in individuals with misophonia. Edelstein et al. (2013) have provided work which pools trigger sound characteristics including sound repetitiveness yet does not include a substantial music subcategory. Utilizing the Cattell–Horn–Carroll model of intelligence, the current study explores the nature of music and music complexity on fluid intelligence, as described by Sternberg (2012). The hypotheses for this study focused on the relationship that complexity and music might have with misophonia. The rate of misophonia in the Mechanical Turk population was hypothesized to be 20%. The …

Cerebellum-Seeded Functional Connectivity Changes In Trait-Anxious Individuals Undergoing Attention Bias Modification Training, Katherine Elwell

All NMU Master's Theses

Anxiety and anxiety related disorders are increasing at a drastic rate in the past decade, with the NIMH reporting that 31.1% of U.S. adults will experience an anxiety disorder at some point in their lives. Anxiety is commonly characterized by increased attention bias to threat. Attention Bias Modification (ABM) is a new treatment used to reduce individual’s attention bias towards threat. The extent to which ABM leads to underlying neural changes is still unknown. The cerebellum is a neglected brain structure, with new research provides evidence that cerebellum’s functional connectivity and shared networks with threat processing regions has a direct …

Neuropsychological Implications Of Nocturnal Hypoxemia In Sickle Cell Disease, Sheena Ram

Theses and Dissertations

Neuropsychological impairments have been observed in both individuals with sleep-disordered breathing and in individuals with sickle cell disease (SCD), but there has been little research on the potential effect of sleep-disordered breathing on neuropsychological function in individuals with SCD. This study aims to examine the effect nocturnal oxygen desaturations have on neuropsychological functioning in individuals with sickle cell disease when compared to those with non-sickle anemia and healthy controls. Thirty-four participants with SCD, 18 non-sickle anemia controls (ACTL), and 29 healthy controls (CTL), ages 9 to 63 years, participating in an IRB-approved Children’s Hospital Los Angeles study of cerebral blood …

The Effectiveness Of A Mindfulness-Based Intervention: A Neuropsychological Perspective Using An Electroencephalography, Elizabeth Mary Grace

Doctor of Psychology (PsyD)

In recent years, there has been a significant increase in mindfulness-related techniques. The willingness to experience emotions fully, just as they are, is a catalyst for psychological change to occur. Mindfulness has been used to alleviate stress and promote healthy living (Lagopoulos et al., 2009). The clinical utility of mindfulness has grown exponentially; however, the neuropsychological process of mindfulness is still being understood. The present study sought to examine the influence of a brief mindfulness intervention on brain activation in college students. A sample (n = 17) of undergraduate participants were randomly assigned into a prepost mindfulness intervention or control …

Relationships Between Age And White Matter Integrity In Children With Phenylketonuria, Erika M. Wesonga

Arts & Sciences Electronic Theses and Dissertations

Objective: Phenylketonuria (PKU) is a hereditary metabolic disorder associated with cognitive compromise. Diffusion tensor imaging (DTI) has allowed detection of poorer microstructural white matter integrity in children with PKU, with decreased mean diffusivity (MD) in comparison with healthy children. However, very little research has been conducted to examine the trajectory of white matter development in this population. The present study investigated potential differences in the developmental trajectory of MD between children with early- and continuously-treated PKU and healthy children across a range of brain regions.

Methods: Children with PKU (n = 31, mean age = 12.2 years) were …

Neuropsychological Instruction: A Process Related Approach In Early Reading Skill Development, Karen Boyle Donahue

PCOM Psychology Dissertations

Proficient and fluent reading ability for all Americans continues to be a highly prioritized, yet under achieved aspiration in current educational institutions. The acquisition of proficient reading fluency and comprehension are, undoubtedly, the most essential priorities in the academic development of school aged children, yet a discouraging number of students continue to struggle with the reading process throughout school aged years. Research has targeted key instructional areas that must be implemented in successful reading curriculum in the early childhood years. Namely, phonological awareness, phonics instruction, reading fluency, vocabulary development, and reading comprehension are core components that must be incorporated into …

Neuropsychological Functioning And Attrition Rates In Outpatient Substance Dependence Treatment, Sandra M. Adams

Dissertations (1934 -)

Numerous neuropsychological factors have been associated with substance dependence, however, very few studies have evaluated the relationship of the neuropsychological functioning and attrition rates in substance dependence treatment. This study examined the relationship of neuropsychological functioning and attrition rates in 68 homeless, substance dependent men participating in outpatient treatment at the 7C's Community Counseling Clinic located in the Guesthouse of Milwaukee, Wisconsin. A neuropsychological battery including the Delis Kaplan Executive Functioning System, the Conners' Continuous Performance Test II, the Wechsler Abbreviated Scale of Intelligence (WASI) and the Wechsler Test of Adult Reading was given to all participants to evaluate neuropsychological …

Top-Down Modulation By Medial Prefrontal Cortex Of Basal Forebrain Activation Of Auditory Cortex During Learning, Candice Monique Chavez

Theses Digitization Project

The experiment tested the hypothesis that the acetylcholine (ACh) release in the rat auditory cortex is greater in rats undergoing auditory classical conditioning compared to rats in a truly random control paradigm where no associative learning takes place and that this is mediated by prefrontal afferent projections influencing the nucleus basalis magnocellularis (NBM), which in turn modulates ACh release in neocortex. Rats with bilateral ibotenic acid lesions of medial prefrontal and agranular insular cortices were tested in an auditory classical conditioning task while ACh was collected from the primary auditory cortex. It was hypothesized that lesions of these prefrontal areas …

Cholinergic Basal Forebrain Involvement In The Acquisition Of Differential Reinforcement Of Low Rate Responding Tasks In Rats, Sean Ryan Corley

Theses Digitization Project

It was hypothesized that 192 IgG-saporin lesions of the basal forebrain cholinergic system (BFCS) would disrupt differential reinforcement of low rate (DRL) learning in an uncued DRL task, but would not impair acquisition and performance in the cued version of the task. Results suggest that BFCS lesions impair vigilance to the external cues despite continued practice in the cued DRL, whereas continuous attention to internally produced cues recovers with extended practice in the uncued DRL.