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Biological Psychology Commons

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Full-Text Articles in Biological Psychology

Early-Life Acetaminophen Exposure Alters Sex-Specific Social And Mate Preference Behaviors In Adolescent And Adult Rats, Anna G. Warner May 2022

Early-Life Acetaminophen Exposure Alters Sex-Specific Social And Mate Preference Behaviors In Adolescent And Adult Rats, Anna G. Warner

University of New Orleans Theses and Dissertations

Epidemiological studies reported associations between early-life exposure Acetaminophen (APAP) exposure and increased risk of Autism Spectrum Disorder (ASD). Rodent studies parallel epidemiological reports, with APAP-exposed animals showing more abnormal social and increased repetitive behaviors. However, mechanisms underlying sex-specific behavioral responses to APAP remain unclear. Here, a rat model was developed to examine possible interactions between APAP and early-life hormonal milieus during the neonatal period of brain sexual differentiation. Subcutaneous (s.c.) injections of either 17�-Estradiol (E2; masculinized) or Letrozole (LTZ; feminized) were administered from Postnatal Days (PD) 1-11 followed by either APAP or saline 45 min after the first injection on …


Utilization Of The Fundamental Attribution Error With Increased Immune System Inflammation, John Odom May 2022

Utilization Of The Fundamental Attribution Error With Increased Immune System Inflammation, John Odom

Biological Sciences Undergraduate Honors Theses

Immune system inflammation is associated with sickness behavior, depressive mood, and alteration of decision-making processes. Because of these cognitive effects, inflammation may also lead to increased use of heuristics, for example the Fundamental Attribution Error (FAE). In the current research, inflammation was experimentally increased using the influenza vaccine, with participants receiving either the vaccine or a placebo injection and completing a measure that tests for the FAE. There were no significant differences between the two conditions regarding the number of personal, situational, or overall attributions made by the participants in the measure that would indicate use of the FAE. However, …