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Full-Text Articles in Biological Psychology
Neuroanatomy In Mild Cognitive Impairment: Relationship To Functional Skills, Treatment Expectancy, And Comorbid Depression, Sara Rushia
Dissertations, Theses, and Capstone Projects
Mild cognitive impairment (MCI) is a neurocognitive disorder defined by cognitive decline in older adults. Although MCI has been studied for decades, there remain important areas to be explored in order to adequately characterize aspects of this disorder that provide information valuable for possible interventions and disease progression to dementia, including a better understanding of the neuroanatomical variables relevant to this disorder. Such neuroanatomical variables include cortical thickness, hippocampal volume, and white matter hyperintensities (WMHs). This dissertation consists of three separate studies aimed at addressing gaps in the literature on MCI in relation to brain morphometrics and under-studied characteristics involved …
Cortisol Administration Normalizes Aberrant Functional Connectivity In Women With Depression, Adam C. Runyan
Cortisol Administration Normalizes Aberrant Functional Connectivity In Women With Depression, Adam C. Runyan
Dissertations
Previous resting-state functional connectivity (rsFC) research has identified aberrant connectivity in several large brain networks in depression, including the default mode (DMN), frontoparietal (FPN), and salience networks (SN). Connectivity of these networks is also related to depressive symptom severity and is affected by cortisol levels. To our knowledge, this is the first study to investigate the effects of acute cortisol administration on rsFC of DMN, FPN, and SN in individuals varying in depression history and severity. We collected resting-state fMRI scans for 74 women with and without a history of depressive disorder after administration of cortisol and placebo using a …
Barriers To Care, Depressive Symptoms, And Moderating Factors Among Patients With Esrd, Amarachukwu O. Nwangwu
Barriers To Care, Depressive Symptoms, And Moderating Factors Among Patients With Esrd, Amarachukwu O. Nwangwu
Honors Theses
End-Stage Renal Disease (ESRD) is the fifth and final stage of Chronic Kidney Disease (CKD) and has been reported to have the highest prevalence rate in the United States, with about 2,242 cases per million in the total population in 2017 (Johansen et al., 2021). Current studies document a high prevalence of depression among patients with ESRD which may lead to increased mortality (Shirazian et al., 2017). Additionally, barriers in access to care, which may be understood as the barriers that prevent individuals from seeking mental health services, has been linked to increased levels of undertreatment (Clement et al., 2012). …