Biological Psychology Commons^™

The Influence Of Depressive Symptoms On Frn Amplitude: An Eeg Study, Jonathan Burton

USC Aiken Psychology Theses

Background: Individuals diagnosed with depression demonstrate differences in neural activation patterns detectable using electroencephalogram (EEG). One of these differences has been specifically linked with the event-related potential (ERP) component called feedback-related negativity (FRN). In participants diagnosed with depression, the FRN has been shown to have larger amplitudes in response to negative feedback. However, previous research has only specifically looked at the difference of this amplitude between groups, specifically those with and those without a diagnosis of depression. Objective: The goal of the current study was to examine whether a continuous range of depressive symptoms in participants can predict FRN amplitudes, …

Exercise Engagement And Longitudinal Change In Alzheimer's Disease Biomarkers, Regional Brain Structure, And Cognitive Functioning, Marta Stojanovic

Arts & Sciences Electronic Theses and Dissertations

No abstract provided.

Hearing And Seeing A Speaker: How Perceptual And Cognitive Factors Modulate The Dynamics Of Audiovisual Speech Perception, Elina Kaplan

Doctoral Dissertations

In face-to-face conversations, listeners process and combine speech information obtained from hearing and seeing the speaker talk. Audiovisual speech typically leads to more robust recognition of speech, as it provides more information for recognition but also as it helps listeners adjust to speaker idiosyncrasies. The goal of the current thesis was to examine how certain perceptual and cognitive factors modulate how listeners use visual speech to facilitate momentary speech perception and to adjust to a speaker’s idiosyncrasies. Results showed that (older) listeners’ sensitivity to cross-modal synchrony is related to the size of the audiovisual interactions during early perceptual processing. Furthermore, …

Validation Of The Barkley Deficits Of Executive Functioning Scale-Short Form, Brian Sheble

Dissertations

The Barkley Deficits of Executive Functioning-Short Form (BDEFS-SF) is a short rating scale measuring executive functioning in adults. The BDEFS-SF was developed using the 5 highest loading questions from the BDEFS-LF. Consequently, the psychometric qualities of the BDEFS-SF were not investigated using formal methods. In this study, the psychometric attributes of the BDEFS-SF were examined using two separate but similar groups. The first group of 264 men and women aged 18-35 years old completed the BDEFS-SF via an internet survey. The second group of 36 men and women aged 18-35 years old completed the BDEFS-SF and individualized assessments of executive …

Cannabinoid-Induced Behavioral Sensitization In Adolescent Sprague-Dawley Rats, Michelle Stone

Electronic Theses, Projects, and Dissertations

Adolescent cannabis use has grown because of increased availability and higher societal acceptance. This increase in cannabis use is problematic as adolescents who experiment with cannabis are more likely to abuse cannabis and experiment with other illicit drugs such as cocaine. The reason for the greater susceptibility to drugs use is unclear and may be the result of altered drug sensitivity after cannabis exposure. Thus, the present investigation used the behavioral sensitization paradigm to examine the behavioral response of early adolescent rats to the cannabinoid agonist CP 55,940 (CP) or cocaine after repeated cannabinoid administration. It was hypothesized that: (1) …

The Effect Of A Voice Treatment On Facial Expression In Parkinson’S Disease: Clinical And Demographic Predictors, Amanda D. Bono

Dissertations, Theses, and Capstone Projects

Parkinson’s disease (PD) is a neurodegenerative disease associated with a wide range of motoric, cognitive, and behavioral symptoms. Impairments in facial mobility and emotional expressivity are common and can impair communication, in turn, affecting daily functioning and quality of life. Previous research suggests that the Lee Silverman Voice Treatment © (LSVT LOUD; Ramig et al., 2001, 2011) increases vocal loudness and facial expressivity in individuals with PD compared to PD and healthy controls. This study extends the literature by examining the effects of LSVT and an articulation-based control treatment (i.e., ARTIC) on multiple aspects of facial expressivity (i.e., emotional frequency …

Dietary Curcumin Promotes Resilience To Chronic Social Defeat Stress In A Highly Susceptible Mouse Strain, Antonio V. Aubry

Dissertations, Theses, and Capstone Projects

Chronic exposure to stress is a risk factor for the development of major depression and post traumatic stress disorder in humans and induces depressive- and anxiety-like phenotypes in rodents. However, there are few pharmacological interventions available that effectively treat maladaptive responses to chronic stress in the clinical setting. One therapeutic agent that has recently shown promise in treating psychiatric disorders is curcumin, a yellow-pigmented polyphenol compound found in the turmeric plant. Curcumin has been shown to prevent the development of stressed-induced depressive-like behavior in rodents and reduce symptoms of depression in clinically diagnosed patients. In this dissertation, I investigated whether …

The Relationship Between Cognitive And Neural Bases Of Metamemory Judgments, Alexandra M. Gaynor

Dissertations, Theses, and Capstone Projects

Metamemory monitoring, the process of making subjective assessments of the status of one’s own memory, is crucial to guiding behavior and effective learning. Past cognitive research has shown that subjective confidence judgments are inferential in nature, and based on cues available at the time of the judgment. When confidence is based on cues that are related to objective memory performance, metamemory accuracy is high. However, past studies have shown that metamemory monitoring tends to be inaccurate because individuals base their confidence on information that is not predictive of memory success, such as the fluency with which items were encoded during …

A Functional Neuroimaging Study Of Self-Regulatory Control In Adults With Gambling And Obsessive-Compulsive Disorders, Nidhi Parashar

Dissertations, Theses, and Capstone Projects

Objective: Recent findings suggest phenomenological similarities across gambling and obsessive-compulsive disorders. The key similarity between the disorders is the failure to inhibit or control a repetitive behavior (or urges to engage in a behavior) and intrusive thoughts. Our current understanding of the neural pathophysiological mechanisms linking gambling and obsessive-compulsive disorders is limited. Thus, the aim of the present study was to examine the functioning of frontostriatal brain regions that support self-regulatory control in adults with gambling and obsessive-compulsive disorders.

Methods: The study compared functional magnetic resonance imaging blood oxygen level dependent response in 19 adults with pathological gambling (PG), …

Curcumin Inhibits The Ikk:Nf-Kappa B Pathway In Neural Fear Circuits, Miguel A. Briones

Dissertations, Theses, and Capstone Projects

The study of how the brain acquires fearful memories has attracted considerable experimental attention, due in part to the promise of discovering novel therapeutic approaches for psychiatric disorders that are characterized by unusually strong and persistent traumatic memories. In recent years, extensive research has focused on studying the neural and molecular mechanisms by which fear memories are acquired, stored, and retrieved in the brain. Once acquired, fear memories may be attenuated using one of 2 procedures: 1) fear extinction, which involves repeated presentation of the fear-arousing stimulus in the absence of an aversive consequence, or 2) interference with the reconsolidation …

Wellness And Karate, Cristina Kumpf

Electronic Theses and Dissertations

The promotion of wellness is an integral part of the counseling field and is considered to be a central focus to the counseling process (Barden, Conley, & Young, 2015; Myers, 1992). The counseling profession adopted the concept of wellness because it harmonizes with many of the founding principles of the ACA and is seen as a process of questing toward optimal health and well-being in body, mind, and spirit (Barden, Conley, & Young, 2015; Myers, 1992; Myers, Sweeney, & Witmer, 2000). Additionally, ACA Code of Ethics (2014) state that counselors “engage in self-care activities to maintain and promote their own …

Parental Stress, Anxiety, And Depression And Child Emotional Intelligence In Children With 22q11.2 Deletion Syndrome, Megan A. Goldfarb

University of New Orleans Theses and Dissertations

Children with chromosome 22q11.2 deletion syndrome (22q11.2DS) have serious medical, psychological, and behavioral symptoms that are stressful to their parents. Higher general intelligence quotients (IQ) and emotional intelligence (EI) in children could allay parental stress. Self-reported stress, anxiety, and depression were measured in parents of children with 22q11.2DS (n=42) and a healthy control group (n=20) in relation to children’s IQ and EI. Children with 22q1.2DS had lower IQ and EI scores. Parental groups did not differ in their reported stress, anxiety, or depression. Children’s IQ and EI levels did not relate to parental measures of affect even in the 22q11.2DS …

Bubble Stream Production By Belugas (Delphinapterus Leucas), Megan Slack

Theses

Bubble stream production in belugas has been poorly characterized and its function is not well understood. I examined behavioral states when producing bubble streams (“bubbling”), and when bubbling calls, to determine whether bubbling was significantly associated with a particular call category or behavioral state. Using 19 hours of video and audio recordings collected over a two-day period, I quantified bubble streams of a 4-month old calf and an unrelated adult female housed together. Based on the overall activity budgets and pool of vocalizations for both animals, I calculated the expected counts of bubble streams with and without vocalizations, assuming that …

Psychopathic Traits And P3 Modulation During Simple And Complex Target Detection Tasks, Olivia Aveson

Student Theses

Psychopathy is notable for traits of impulsivity, irresponsibility, and proneness to boredom, characteristics that are all substrates of executive function. However, event-related potential (ERP) P3 studies of attention-related abnormalities in the context of psychopathic traits have yielded inconsistent results (Gao & Raine, 2009). The current study attempted to address these discrepancies by investigating the effects of psychopathic traits on P3s during two attentional tasks. Two groups of ERP participants (n = 28) who had high (T score greater than or equal to 50) or low (T score less than or equal to 40) Psychopathic Personality Inventory – …

Examining The Associative Learning And Accumbal Dopaminergic Mechanisms Of Caffeine Reinforcement, Curtis Bradley

Electronic Theses and Dissertations

Caffeine is the most consumed psychoactive substance in the world, and most caffeine consumption in coffee and energy drinks is intended to produce a psychoactive effect. However, caffeine is not a primary reinforcer in preclinical paradigms – non-human species do not reliably take the drug to produce a psychoactive effect. However, caffeine is a ‘reinforcement enhancer’ in preclinical models; the effects of caffeine increase the motivation to obtain other non-drug reinforcers. The overall goal of this project was to determine if these reinforcement enhancing effects of caffeine could promote caffeine self-administration and to subsequently investigate the behavioral and neurochemical underpinnings …

Effort-Related Motivational Dysfunctions: Behavioral And Neurochemical Studies Of The Wistar-Kyoto Rat Model Of Depression, Brendan Abbott

Masters Theses

Depression and related disorders are characterized by motivational dysfunctions, including deficits in behavioral activation and exertion of effort. Animal models of relevance to depression represent a critical starting point in elucidating the neurobiological mechanisms underlying motivational dysfunctions. The present study explored the use of the Wistar-Kyoto (WKY) animal model of depression to examine effort-related functions as measured by voluntary wheel running and performance on a mixed fixed ratio 5/progressive ratio (FR5/PR) operant task. Given the known link between activational aspects of motivation and the mesocorticolimbic dopamine (DA) system, the behavioral effects of d-amphetamine (0.5 and 1.0 mg/kg, IP), a psychostimulant …

Functional Polymorphisms Of Alcohol Metabolism Genes And Their Protection Against Alcoholism Via Gene Therapy: A Systematic Review, Olivia Tzeng

Psychological Science Undergraduate Honors Theses

Around 45% of East Asians are unable to fully metabolize ethanol due to functional

polymorphisms of alcohol metabolism genes, specifically alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH). These individuals display high levels of toxic blood acetaldehyde when consuming alcohol, causing symptoms such as tachycardia, vomiting, and flushing. The studies included in this review examine how functional polymorphisms of ADH and ALDH protect against alcoholism in addition to how polymorphisms can be utilized as protection against alcoholism via gene therapy. The studies included found that carriers of the ADH and ALDH polymorphisms were 66 to 99% genetically protected against alcoholism. Through …

Coping With Stereotype Threat: Multiple Identities And The Role Of Gender-Professional Identity Integration (G-Pii), Amy Jia Ying Lim

Dissertations and Theses Collection (Open Access)

Negative stereotypes concerning females’ inferior quantitative abilities continue to hinder females’ preference and success in science, technology, engineering, and mathematics (STEM) fields. Studies on multiple identities show that priming females with a favorable identity, a social identity they possess that is associated with superior quantitative abilities, can reduce the aversive effects of stereotype threat. However, this line of research overlooked the fact that females manage their multiple identities in different ways and therefore respond to identity cues differently. This paper examined the role of gender-professional identity integration (G-PII), an individual difference on perceived compatibility of gender and professional identities, in …

The Immediate And Long-Lasting Cognitive Consequences Of Adolescent Chronic Sleep Restriction, Kerry Howard

Seton Hall University Dissertations and Theses (ETDs)

Adolescence is a critical developmental period. An important change that occurs in adolescence is the neurological maturation for adult-type cognitive abilities. Research has linked adequate sleep quantity to successful learning and memory capabilities. However, due to a shift in sleep timing drive in adolescence, in combination with early awakening for school, the adolescent population is experiencing chronic sleep restriction (CSR). What repercussions to long-term memory capabilities could CSR in adolescence have immediately and are the consequences long-lasting? The present study modeled human adolescent CSR in rats through four hours of sleep deprivation for five days, followed by two days of …

Attentional Sub-Processes Involved With Emotional Eating, Gregory Denke

University of New Orleans Theses and Dissertations

Emotional eating behavior is characterized by eating a large amount of calorie dense sweet and/or high fat foods in an attempt to control, cope with, or avoid negative emotions. Numerous factors are likely to contribute to emotional eating behavior, including attentional factors, such as rumination and avoidance coping. Rumination based emotional eating (attention focused on negative stimuli while mindlessly eating) is often utilized to improve mood while dwelling on problems. However, for those inclined to escape/avoid troublesome thoughts, another type of emotional-eating pattern may be used. By focusing attention on food, emotional eating is believed to distract individuals from negative …

A Program Evaluation Of A Drug And Alcohol Family Treatment Program, Katrina Ramirez

Doctoral Dissertations

The current study is a program evaluation at John Muir Behavioral Health, Center for Recovery. The research determined the effectiveness of the program at Center for Recovery that is offered to patients that struggle with substance use disorder and their families. The purpose of this study is to assess patients’ behavioral, cognitive and social/environmental factors as it relates to their commitment to sobriety and examine how the involvement of family members influences the patient’s recovery process. I utilized a mixed methodology of quantitative and qualitative interviews of patients and family members. The findings suggest depressive symptoms were negatively correlated with …

Literature Review And Proposal: Yoga As Group Exercise Involving Oxytocin Release For Positive Mood Improvement, Rachel Fenton

Honors Projects

A literature review discusses yoga and health involving oxytocin creates the premise for a proposal combining the knowledge of yoga and its health benefits along with oxytocin's potential involvement during group exercise, yoga specifically. The proposed study's results of oxytocin measures and questionnaires have the potential to develop an understanding of the possible impacts of yoga on mood, particularly relationships between group exercise and yoga, which may help develop forms of group exercise or implement group yoga to assist or replace treatment for stress-caused or stress-related disorders.

Memory Complaint Profiles In Dementia Populations Utilizing The Memory Complaints Inventory, Becca N. Johnson

MSU Graduate Theses

The Memory Complaints Inventory (MCI) is a self-report questionnaire developed by Paul Green to provide further effort-related evidence in neuropsychiatric practice. It is comprised of nine subscale scores, in addition to the imbedded Plausible and Implausible symptom validity scales. The current study utilized archival MCI scores in dementia populations to determine the presence of, and difference between, genuine memory impairment profiles in separate subgroups of cognitive impairment. The study sample consisted of 244 adults presenting to an outpatient neuropsychology practice for evaluation of memory impairment. The diagnostic categories of the sample consisted of Alzheimer’s Disease (n = 21), Vascular …

Detecting Suicide Risk From Wristworn Activity Tracker Data Using Machine Learning Approaches, Pallavi Atluri

Electrical Engineering Theses

Suicide is a prevalent cause of death worldwide and depression is a primary concern of many suicidal acts. It is possible that an individual during depression never has any suicidal thoughts at all. On the other hand, some individuals in stable condition with no apparent symptoms of depression feel urges to commit suicide (suicidal ideation). Many such individuals never let anyone know what they are feeling or planning. Suicidal ideation considered an important precursor to suicidal acts.

Detecting the suicide risk in individuals with mood disorders is a major challenge. The current clinical practice to assess suicide risk in these …

Mental Disorders As Brain Disorders: The Impact On Stigma Of Neuroscience-Based Mental Health Education, Katherine Tighe

Honors Theses

Stigmatization of mental illness is undoubtedly detrimental to those with mental health concerns as it limits employment, self-esteem and social support (Markowitz, 1998). In effort to combat the issue of stigma, previous research has evaluated the effectiveness of education as a method to reduce stigma in a college sample; finding that peer-led presentations are effective in reducing stigma (Kosyluk et al., 2016). The current study sought to evaluate the effectiveness of neuroscience-oriented presentation for reducing the stigma of mental illness among college students. Researchers asked 53 Union College students to complete seven-item Social Distance Scale (SDS; Penn et al., 1994) …

Biological Signatures Of Emotion Regulation In Children, Sarah Myruski

Dissertations, Theses, and Capstone Projects

Emotion regulation (ER) is a key predictor of positive adjustment throughout the lifespan. Despite decades of research on discrete ER strategy use, ER may be more appropriately measured in terms of the breadth of emotional range, or the degree to which one can flexibly modulate emotional responses. Yet little is known about ER flexibility in childhood. Also, given the crucial role of caregiver support in children’s emotional lives, ER may be most accurately measured in developmentally appropriate and ecologically valid social contexts. Further, few developmental studies have capitalized on the growing evidence base surrounding biological signatures of ER. This study …

Neural Hypervigilance In Trauma-Exposed Women, Seungyeon A. Yoon

Dissertations, Theses, and Capstone Projects

Trauma-exposed people often experience hypervigilance, which is a tonic condition of elevated alertness and excessive scanning for potential threat. A cardinal feature of hypervigilance is that no actual threat is needed to evoke or maintain the over-alertness and heightened affective response. However, most neuroimaging research in trauma to date has only focused on reactivity to an actual threat. Thus, the overarching aim of this dissertation was to investigate neural signatures and salivary markers of post-trauma hypervigilance in the absence of threat that can cause impairment in daily functioning and contribute to developing other trauma-related symptoms such as heightened threat reactivity. …

The Effect Of Early Life Photoperiod Manipulation On Cocaine-Induced Behavioral Sensitization In Male And Female Japanese Quail, Shannon Elizabeth Eaton

Theses and Dissertations--Psychology

Estrogens seem to play a role in the locomotor activating effects of cocaine. Japanese quail provide a good model for hormonal manipulation as alterations of their photoperiod controls hormone levels. The current study aims to examine the role of early life photoperiod manipulation in cocaine-induced behavioral sensitization in quail. It was expected that if quail were raised on a short photoperiod, they would have a reduction in gonadal hormones and this reduction in hormones would affect the acquisition of cocaine-induced behavioral sensitization. Quail were raised on an 8L:16D or a 16L:8D light cycle. Following 2 days of habituation, quail were …

Potential Candidates For Treating Deficits Associated With Developmental Ethanol Exposure In A Rodent Model: Solidago Nemoralis & Dimethoxybenzylidene-Anabasine, Logan James Fields

Theses and Dissertations--Psychology

Prenatal alcohol exposure (Fetal Alcohol Syndrome [FAS] and Fetal Alcohol Spectrum Disorders [FASD’s]) represents the leading preventable cause of intellectual disabilities in the western world, with FASDs estimated to affect approximately 2-5% of live births in the United States at an approximate annual cost of $3.6 billion (CDC, 2015; May et al., 2009). Ethanol (ETOH) exposure during development can lead to a variety of long-term behavioral impairments including problems with executive functioning, motor coordination, spatial learning, attention, and hyperactivity (Jones, 2011; Mattson & Riley, 1998). Much research has been conducted to develop pharmacological and/or environmental interventions to reduce these deficits, …

Insulin Modulates The Strong Reinforcing Effects Of Nicotine And Changes In Insulin Biomarkers In A Rodent Model Of Diabetes, Bryan Cruz

Open Access Theses & Dissertations

This study examined whether the strong reinforcing effects of nicotine and changes in insulin biomarkers observed in diabetic rats are modulated via insulin. A model of diabetes was employed involving administration of streptozotocin (STZ), which produces hypoinsulinemia in rats. The present study included vehicle- or STZ-treated rats that received sham surgery or an insulin pellet. Two-weeks later, the rats were given extended access to intravenous self-administration (IVSA) of saline or nicotine. Concomitant changes in food intake, water responses, and body weight were assessed during 12 days of IVSA. After the last session, plasma levels of insulin, leptin, amylin, and glucagon-like …