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Oxytocin Does Not Mediate Lithium Chloride (Licl)-Induced Non-Social Environmentally Conditioned Disgust Behaviour (Anticipatory Nausea) In Male Rats, Vangel Matic

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Introduction. Anticipatory Nausea (AN) is a form of classical conditioning in which the effects of a nausea-inducing substance, such as lithium chloride (LiCl), become associated with a social or environmental context. In rats, AN can be measured by the frequency of conditioned gaping behaviour, displayed when rats are re-exposed to a context previously associated with LiCl. Oxytocin (OT) may be involved in the mediation of socially conditioned disgust, though its role in mediating non-social environmentally conditioned disgust is unclear. The purpose of the present study was to investigate the role of OT in mediating environmentally conditioned disgust. It was hypothesized …