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Full-Text Articles in Biological Psychology
Behavioral Deficits Across Development In A Novel Mouse Model Of Fetal Ethanol Effects, Andrew B. Hawkey
Behavioral Deficits Across Development In A Novel Mouse Model Of Fetal Ethanol Effects, Andrew B. Hawkey
Theses and Dissertations--Psychology
Fetal Alcohol Spectrum Disorders (FASD) are a spectrum of anatomical, developmental and neurobehavioral impairments resulting from ethanol (ETOH) exposure during fetal development. Efforts to develop and screen novel pharmacotherapies against fetal ETOH effects depend heavily upon rodent models to provide indicators of the safety and efficacy of such compounds, in addition to helping better understand the underlying mechanisms to develop and test these pharmacotherapies. The following experiments describe the development of a novel mouse model of FASD using behavioral batteries to assess behavioral or cognitive deficits in juvenile and adolescent offspring (Experiment 1, Experiment 2) and whether deficits with this …