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Full-Text Articles in Biological Psychology

Methamphetamine-Induced Conditioned Place Preference In Adolescent Male And Female Mice Of Two Strains, Andre Bevil Toussaint Aug 2017

Methamphetamine-Induced Conditioned Place Preference In Adolescent Male And Female Mice Of Two Strains, Andre Bevil Toussaint

Theses and Dissertations

We used a conditioned place preference paradigm to test the rewarding effects of methamphetamine (1mg/kg) in adolescent male and female mice of two strains. We found that methamphetamine induced conditioned place preference in female C57Bl/6 and male 129/SvEv mice, but not female 129/SvEv or male C57Bl/6 mice.


Effects Of Self-Affirmation On Emotion And Cardiovascular Responses, Wei-Ju Chen Aug 2017

Effects Of Self-Affirmation On Emotion And Cardiovascular Responses, Wei-Ju Chen

Theses and Dissertations

Self-affirmation is the act of focusing on important aspects of the self, such as personal values and characteristic. Benefits of self-affirmation have been documented in past research. However, the immediate impacts of self-affirmation on cardiovascular responses have not been fully explored. Therefore, the present study examined such effects both during and consequent to the practice of self-affirmation. One hundred and twenty-five participants completed the study. A within-subject design was used, in which each participant went through both the control and self-affirmation conditions (the order of presentation was counterbalanced). In the self-affirmation condition, participants were asked to write about their top-ranked …


Antidepressant-Like Effects Of Amisulpride, Ketamine, And Their Enantiomers On Differential-Reinforcement-Of-Low-Rate (Drl) Operant Responding In Male C57/Bl/6 Mice, Doug Smith Jan 2017

Antidepressant-Like Effects Of Amisulpride, Ketamine, And Their Enantiomers On Differential-Reinforcement-Of-Low-Rate (Drl) Operant Responding In Male C57/Bl/6 Mice, Doug Smith

Theses and Dissertations

Major depressive disorder (MDD) is a widespread psychiatric disorder that affects millions of people worldwide and is hypothesized to occur due to impairments in several neurotransmitter systems, including the monoaminergic and glutamatergic neurotransmitter systems. Antidepressant medications targeting multiple monoamine neurotransmitters have been shown to be effective for the treatment of depression. Racemic amisulpride is an atypical antipsychotic that has been used at low doses to treat dysthymia, a mild form of depression, and functions as an antagonist at DA2/3, 5-HT2B, and 5-HT7 receptors. Recent preclinical studies have suggested that the S(+) isomer may be more …


Integrating Genetics And Neuroimaging To Study Subtypes Of Binge Drinkers, Megan E. Cooke Jan 2017

Integrating Genetics And Neuroimaging To Study Subtypes Of Binge Drinkers, Megan E. Cooke

Theses and Dissertations

Risky alcohol use is a major health concern among college students, with 40.1% reporting binge drinking (5 or more drinks in one occasion) and 14.4% reporting heavy drinking (binge drinking on 5 or more occasions) in the past month. Risky alcohol use is thought to be the result of a complex interplay between genes, biological processes, and other phenotypic characteristics. Understanding this complex relationship is further complicated by known phenotypic heterogeneity in the development of alcohol use. Developmental studies have suggested two pathways to risky alcohol use, characterized by externalizing and internalizing characteristics, respectively. However, the underlying biological processes that …