Open Access. Powered by Scholars. Published by Universities.®
- Discipline
- Institution
- Keyword
-
- Anticipation (1)
- Anxiety (1)
- Behavioral Phenotyping (1)
- Canid (1)
- Categorization (1)
-
- Depression (1)
- Discrimination (1)
- Dog (1)
- Drug (1)
- Drug abuse (1)
- GABA (1)
- GABAA (1)
- Icss (1)
- Information (1)
- Intracranial self-stimulation (1)
- Knockout (1)
- Learning (1)
- NPU (1)
- Perception (1)
- Processes (1)
- Psychosis (1)
- Reward (1)
- Schizophrenia (1)
- Startle (1)
- Threat (1)
- Toluene (1)
- Uncertainty (1)
- VMAT1 (1)
Articles 1 - 5 of 5
Full-Text Articles in Biological Psychology
If Or When? Uncertainty's Role In Anxious Anticipation, Kenneth P. Bennett
If Or When? Uncertainty's Role In Anxious Anticipation, Kenneth P. Bennett
Theses and Dissertations
Uncertainty is often associated with subjective distress and a potentiated anxiety response. Occurrence uncertainty (OU), or the inability to predict if a threat will occur, has never been compared experimentally with temporal uncertainty (TU), or the inability to predict when a threat will occur. The current study aimed to 1) directly compare the eye-blink startle responsivity of OU and TU, 2) develop a more effective task for isolating uncertain anticipation, and 3) better understand the relationship between individual differences in the intolerance of uncertainty and uncertain anticipation startle responsivity. The novel study showed that OU anticipation is more anxiety provoking …
An Analysis Of Canine Processing Of Stimulus Compounds Varying In Light And Sound Intensity, Katherine O. Compitus
An Analysis Of Canine Processing Of Stimulus Compounds Varying In Light And Sound Intensity, Katherine O. Compitus
Theses and Dissertations
A dog was trained to respond deferentially to two light-sound compounds. The dog was then tested with combinations of additional light and sound intensities. The dog appeared to use the information provided by both stimulus dimensions. This research is relevant to the understanding of information processing, specifically categorization and generalization.
Gap Junction Communication In Memory Retrieval And Extinction Of Cocaine Seeking, Michael Fitzgerald
Gap Junction Communication In Memory Retrieval And Extinction Of Cocaine Seeking, Michael Fitzgerald
Theses and Dissertations
Blocking drug-associated memory retrieval or enhancing extinction of drug-seeking behavior are two strategies that could limit relapse in drug addicts. The loci of retrieval and extinction memory processes include the prelimbic medial prefrontal cortex and the infralimbic medial prefrontal cortex, respectively. The neurochemical and synaptic mechanisms underlying drug-related behavior have received considerable attention, but extrasynaptic mechanisms are relatively unexplored. One form of cellular communication, gap junction communication, may play a role in drug-related learning and memory. Gap junction communication between neurons and astrocytes provide a cytoplasmic continuity between connected cells and both neuronal and astrocytic gap junction communication have been …
Behavioral Phenotyping Of Vmat1 Knockout Mice: Relevance To Neuropsychiatric Disorders, Kevin A. Webster Ph.D.
Behavioral Phenotyping Of Vmat1 Knockout Mice: Relevance To Neuropsychiatric Disorders, Kevin A. Webster Ph.D.
Theses and Dissertations
Schizophrenia is a debilitating mental disorder that causes a large economic burden and is prevalent across all cultures and countries around the world. Although both environmental factors and genetics are known to play an important role in the etiology of schizophrenia, the exact role of genetics and its interaction with environmental factors in an individual’s predisposition to develop schizophrenia is poorly understood. Schizophrenia is characterized by symptoms that include positive symptoms (e.g. delusions, hallucinations, disorganized thinking and speech), negative symptoms (e.g. avolition, anhedonia, depressive-like behavior), and cognitive dysfunctions (e.g. executive functioning deficits in learning and memory, attention, and vigilance). Genomic …
Acute And Chronic Effects Of Inhalants In Intracranial Self-Stimulation, Matthew Tracy
Acute And Chronic Effects Of Inhalants In Intracranial Self-Stimulation, Matthew Tracy
Theses and Dissertations
Inhalants are a loosely defined diverse group of volatile substances which people abuse. Despite widespread misuse of inhalants, there are limited preclinical methods available to study the reinforcement-like properties of inhalants. One procedure which has demonstrated substantial promise as a tool to investigate inhalant pharmacology is the intracranial self-stimulation (ICSS) procedure. ICSS utilizes pulses of electrical stimulation to the mesolimbic reward pathway to serve as a temporally defined and controlled operant reinforcer with a highly adjustable efficacy. The first aim of the project was to characterize the effects of commonly abused inhalants: including toluene, trichloroethane, nitrous oxide, isoflurane and R134a …