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6-OHDA

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Full-Text Articles in Biological Psychology

Effects Of Neonatal Ethanol Exposure In Normal And Dopamine Deficient Rats, Jessica Luz Razo May 2021

Effects Of Neonatal Ethanol Exposure In Normal And Dopamine Deficient Rats, Jessica Luz Razo

Electronic Theses, Projects, and Dissertations

Attention deficit hyperactivity disorder (ADHD) is a common developmental disorder characterized by impulsivity, inattention, and hyperactivity. In rodents, neonatal 6-OHDA lesions is an established model of ADHD because it produces symptoms of hyperactivity and cognitive deficits that improve following psychostimulant treatment. Recently, early alcohol exposure in rodents has also been suggested as a model of ADHD due to the high prevalence of ADHD in children exposed prenatally to alcohol. However, children exposed to prenatal alcohol differ in symptoms from children with idiopathic ADHD, suggesting that ADHD caused by prenatal alcohol exposure may be a special subtype of ADHD or a …