Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 1 of 1
Full-Text Articles in Biological Psychology
Dietary Curcumin Promotes Resilience To Chronic Social Defeat Stress In A Highly Susceptible Mouse Strain, Antonio V. Aubry
Dietary Curcumin Promotes Resilience To Chronic Social Defeat Stress In A Highly Susceptible Mouse Strain, Antonio V. Aubry
Dissertations, Theses, and Capstone Projects
Chronic exposure to stress is a risk factor for the development of major depression and post traumatic stress disorder in humans and induces depressive- and anxiety-like phenotypes in rodents. However, there are few pharmacological interventions available that effectively treat maladaptive responses to chronic stress in the clinical setting. One therapeutic agent that has recently shown promise in treating psychiatric disorders is curcumin, a yellow-pigmented polyphenol compound found in the turmeric plant. Curcumin has been shown to prevent the development of stressed-induced depressive-like behavior in rodents and reduce symptoms of depression in clinically diagnosed patients. In this dissertation, I investigated whether …