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Articles 1 - 14 of 14

Full-Text Articles in Biological Psychology

The Psychotherapeutic Effects Of Consumer-Grade Eeg Neurofeedback On Mental Health And Well-Being, Madeline Slack Sep 2022

The Psychotherapeutic Effects Of Consumer-Grade Eeg Neurofeedback On Mental Health And Well-Being, Madeline Slack

Electronic Thesis and Dissertation Repository

The current study assessed whether pairing mindfulness meditation with consumer-grade neurofeedback (using Muse) would be a feasible and satisfying (i.e., fulfillment and pleasure) intervention for mental health and well-being. This was assessed via a four-day mindfulness program where participants (N=34) were assigned to mindfulness with neurofeedback (n=17) or guided meditation (control; n=17) group. On each day of the program, participants engaged in two mindful sessions (five minutes each) in the morning and afternoon. Participants were administered a series of affective measures before and after the program, as well as throughout. Upon completion, participants were asked to rate …


Putting 'Dopamine Overdose' To The Test: A Psychopharmacological Investigation In Parkinson's Disease And Healthy Volunteers, Andrew Vo Jan 2020

Putting 'Dopamine Overdose' To The Test: A Psychopharmacological Investigation In Parkinson's Disease And Healthy Volunteers, Andrew Vo

Electronic Thesis and Dissertation Repository

Dopaminergic therapy prescribed to address motor symptoms in Parkinson’s disease (PD) is done at the expense of some cognition functions. It has been hypothesized that whether a given function is improved or impaired by medication depends on the baseline dopamine levels within underlying brain regions. Areas most affected by PD and severely dopamine depleted are predicted to benefit from dopaminergic therapy. Regions with less dopamine deficiency are predicted to worsen from excessive dopamine stimulation. This theoretical framework is known as the dopamine overdose hypothesis. The central aim of this thesis was to critically test the straightforward predictions put forward by …


In Search Of Psychiatric Kinds: Natural Kinds And Natural Classification In Psychiatry, Nicholas Slothouber Oct 2019

In Search Of Psychiatric Kinds: Natural Kinds And Natural Classification In Psychiatry, Nicholas Slothouber

Electronic Thesis and Dissertation Repository

In recent years both philosophers and scientists have asked whether or not our current kinds of mental disorder—e.g., schizophrenia, depression, bipolar disorder—are natural kinds; and, moreover, whether or not the search for natural kinds of mental disorder is a realistic desideratum for psychiatry. In this dissertation I clarify the sense in which a kind can be said to be “natural” or “real” and argue that, despite a few notable exceptions, kinds of mental disorder cannot be considered natural kinds. Furthermore, I contend that psychopathological phenomena do not cluster together into kinds in the way that paradigmatic natural kinds (e.g., chemical …


Investigating How Neural Entrainment Relates To Beat Perception By Disentangling The Stimulus-Driven Response, Aaron Wc Gibbings Jul 2019

Investigating How Neural Entrainment Relates To Beat Perception By Disentangling The Stimulus-Driven Response, Aaron Wc Gibbings

Electronic Thesis and Dissertation Repository

Beat perception – the ability to perceive a steady pulse in music – is nearly ubiquitous in humans, but the neural mechanisms underlying this ability are unknown. A growing number of electroencephalography (EEG) studies suggest that beat perception is related to neural entrainment, a phenomenon in which cyclic changes in the excitability of populations of neurons synchronize with a rhythmic stimulus. However, the relationship between acoustically-driven and entrainment-driven neural activity is unclear. This thesis presents EEG research that extends our understanding neural entrainment is related to beat perception by characterizing, equating, and finally removing the stimulus-driven response in the neural …


The Neural Mechanisms Underlying The Perception And Production Of Learned Vocalizations In Songbirds, Shannon Katie Mischler Oct 2017

The Neural Mechanisms Underlying The Perception And Production Of Learned Vocalizations In Songbirds, Shannon Katie Mischler

Electronic Thesis and Dissertation Repository

Songbirds produce a wide array of vocalizations, including song, and learned and innate calls. Songs and calls can be functionally defined. Songs are typically used to attract potential mates and defend one’s territory, whereas calls are used for everything else, such as advertising the presence of a predator, or location of a food source, and maintaining contact with members of one’s flock. The purpose of this thesis was to better understand the neural mechanisms underlying call production and perception in two songbird species; the black-capped chickadee (Poecile atricapillus) and the zebra finch (Taeniopygia guttata). My objectives …


A Diffusion Tensor Imaging Study Of Motor Fibre Path Integrity And Overt Responsiveness In Disorders Of Consciousness, Clara A. Stafford Aug 2017

A Diffusion Tensor Imaging Study Of Motor Fibre Path Integrity And Overt Responsiveness In Disorders Of Consciousness, Clara A. Stafford

Electronic Thesis and Dissertation Repository

This study investigated the relationship between motor thalamo-cortico-cerebellar fibre path integrity and overt responsiveness in patients with disorders of consciousness (DOC). Additionally, we investigated the potential of imaging these motor tracts at ultra-high fields. Study I and II aimed to map the white matter connections of motor execution fibres in DOC patients. Our results showed significant reductions in motor fibre path integrity across DOC diagnostic categories. Study III and IV aimed to develop a 7T MRI Diffusion Tensor Imaging (DTI) sequence. We optimized this sequence to image motor fibre paths in DOC patients. We concluded that, in healthy controls, probabilistic …


The Influence Of Estrogen On Sex Differences In Chemotherapy-Induced Nausea And Vomiting (Cinv), Danna L. Zevy Apr 2017

The Influence Of Estrogen On Sex Differences In Chemotherapy-Induced Nausea And Vomiting (Cinv), Danna L. Zevy

Electronic Thesis and Dissertation Repository

Chemotherapy-induced nausea and vomiting (CINV) is one of the most distressing events that affects the quality of life of cancer patients. Evidence suggests that females are more susceptible to CINV than males, but the mechanism remains unknown. The current thesis examined whether higher levels of circulating estrogens in females contributes to this sex difference. CINV was analyzed in a pediatric oncology population, where it was revealed female patients demonstrate increased delayed CINV relative to male patients, in the post-pubertal age group. CINV was also studied by examining the influence of the estrous cycle on anticipatory nausea (AN) in rats. This …


Neural And Behavioural Responses To Rewards And Losses In Early Development: A Functional Magnetic Resonance Imaging Study, Niki Hosseini-Kamkar Sep 2015

Neural And Behavioural Responses To Rewards And Losses In Early Development: A Functional Magnetic Resonance Imaging Study, Niki Hosseini-Kamkar

Electronic Thesis and Dissertation Repository

Functional magnetic resonance imaging (fMRI) was used to investigate the neural and behavioural correlates of learning from rewards and losses in children. Greater blood-oxygen-level dependent (BOLD) responses in the ventral striatum (VS) and the ventromedial prefrontal cortex (VMPFC) were found when participants received rewards compared to when they missed out on an opportunity to receive rewards. In contrast, greater BOLD responses in the anterior insula (AI) and the anterior cingulate cortex (ACC) were found when participants received losses compared to when they avoided losing. The BOLD response to rewards in the VS and VMPFC correlated positively with the tendency to …


The Role Of Androgens In Life History Theories Of Attachment, Janani S. Sankar Aug 2015

The Role Of Androgens In Life History Theories Of Attachment, Janani S. Sankar

Electronic Thesis and Dissertation Repository

Life history theories (LHTs) of attachment address how attachments to caregivers in infancy/childhood and to romantic partners in adulthood are used to negotiate mating and reproductive choices. Greater insecure-avoidant attachment has been suggested to be associated with the adoption of a low-investment, short-term reproductive strategy. The role of sex hormones, including the androgen testosterone (T), in the development of attachment-related reproductive strategies has been speculated in some LHTs. This research tested an integrated-LHT model of early environment, attachment, and reproductive strategies in men, using structural equation modeling. Androgen-related effects were hypothesized to occur prenatally and/or in adulthood, consistent with various …


Self-Referential Processing: An Investigation Of The Mediating Role Of Alpha Power, Tanaz Javan Sep 2014

Self-Referential Processing: An Investigation Of The Mediating Role Of Alpha Power, Tanaz Javan

Electronic Thesis and Dissertation Repository

The EEG correlates of valenced self- and other-referential processing (SRP-ORP) are relatively little understood. This study examined the immediate effects of mindfulness meditation (MM) and EEG alpha neurofeedback (NFB) on resting state EEG alpha amplitudes and alpha event related (de-)synchronization (ERD/S) during an experimental implicit and explicit SRP-ORP task. Undergraduate students (n = 93) were randomized to a single session of MM, NFB alpha synchronization training (“alpha-up”), NFB alpha desynchronization training (“alpha-down”), or sham (placebo control) NFB before completing the Visual-Verbal Self-Other Referential Processing Task (VV-SORP-T). A reduction in resting-state alpha power over posterior cortex was observed across groups relative …


Associations Between Hypothalamic-Pituitary-Adrenal Axis System Gene Variants And Cortisol Reactivity In Preschoolers: Main Effects And Gene-Environment Interactions, Haroon I. Sheikh Jun 2014

Associations Between Hypothalamic-Pituitary-Adrenal Axis System Gene Variants And Cortisol Reactivity In Preschoolers: Main Effects And Gene-Environment Interactions, Haroon I. Sheikh

Electronic Thesis and Dissertation Repository

Exposure to stressful events during early development has consistently been shown to produce long lasting effects on the hypothalamic-pituitary-adrenal (HPA) axis, which may increase vulnerability to mood and anxiety disorders. Recently reported genetic association studies indicate that these disorders may be influenced, in part, by gene-environment interactions (GxE) involving polymorphisms within the corticotrophin-releasing hormone and monoaminergic system genes. However, little is known about how genetic variants and life stress work to shape children’s neuroendocrine reactivity and emerging symptoms. Therefore, the aim of this thesis is to examine main effects of candidate genes and GxE on the neuroendocrine stress response and …


Timing Of Developmental Stress And Phenotypic Plasticity: Effects Of Nutritional Stress At Different Developmental Periods On Physiological And Cognitive-Behavioral Traits In The Zebra Finch (Taeniopygia Guttata), Buddhamas Kriengwatana Aug 2013

Timing Of Developmental Stress And Phenotypic Plasticity: Effects Of Nutritional Stress At Different Developmental Periods On Physiological And Cognitive-Behavioral Traits In The Zebra Finch (Taeniopygia Guttata), Buddhamas Kriengwatana

Electronic Thesis and Dissertation Repository

Developmentally plastic organisms can respond to stressful environmental conditions by altering multiple aspects of their phenotype, often in a permanent fashion. The timing of developmental stress influences these phenotypic alterations because the prioritization of resources to traits necessary to overcome the stressor may be costly for the development of other traits. Despite the importance of this timing, few studies in birds have accounted for it, and those that have usually examined the effect on a single or few variables. This dissertation addresses the outstanding issues regarding i) the effects of timing of developmental stress on developmental plasticity, and ii) the …


Fmri Reveals The Neural Correlates Of Real And Pantomimed Tool Use In Humans, Joseph Umberto Paciocco Aug 2012

Fmri Reveals The Neural Correlates Of Real And Pantomimed Tool Use In Humans, Joseph Umberto Paciocco

Electronic Thesis and Dissertation Repository

Although functional magnetic resonance imaging (fMRI) can be used to study the neural mechanisms underlying greatly expanded cognitive functions in humans like tool use, surprisingly little fMRI research has been done on actual tool use. In fact, due to technical constraints, most fMRI studies have used pantomimed actions as a proxy for real use. However, human neuropsychology patients who are impaired at pantomiming often improve when handling a tool suggesting potential neural differences. We used fMRI to record brain activation while 13 right-handed participants performed one of two tasks, real or pantomime tool use with one of two tools, a …


Contributions Of Signal-Detection Mechanisms And Semantic Memory Representations To Famous Name Recognition, Ben P. Bowles Aug 2011

Contributions Of Signal-Detection Mechanisms And Semantic Memory Representations To Famous Name Recognition, Ben P. Bowles

Electronic Thesis and Dissertation Repository

In past research, investigators have often used the recognition memory paradigm to study the cognitive and neural processes that permit the ability to accurately assess whether or not stimuli are familiar. This paradigm involves presenting stimuli to participants in a study phase, and examining their later recognition of them when these stimuli are subsequently presented again in a later test phase. It is not well understood, however, whether the same mechanisms that support familiarity assessment in recognition memory also support familiarity based on general life experience (e.g., recognizing a famous celebrity in daily life). To address this, I implemented modified …