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Full-Text Articles in Biological Psychology
Neuroimaging And Cognitive Outcomes In Adults With Human Immunodeficiency Virus And Early Life Stress, Laurie M. Baker
Neuroimaging And Cognitive Outcomes In Adults With Human Immunodeficiency Virus And Early Life Stress, Laurie M. Baker
Dissertations
Brain abnormalities persist in individuals with human immunodeficiency virus (HIV) despite the use of highly active antiretroviral therapy (HAART). To date, limited work has focused on the association between early life stress (ELS) and brain integrity in individuals with HIV, although ELS is highly prevalent in this population. The present study was conducted to determine whether ELS corresponds to the expression of persistent HIV–related neuroimaging abnormalities and cognitive dysfunction. A total of 130 HIV+ individuals on HAART and 76 HIV– individuals underwent 3T structural magnetic resonance imaging, diffusion tensor imaging, and neuropsychological assessment. Individuals were free of major psychiatric illness …