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Articles 1 - 3 of 3
Full-Text Articles in Biological Psychology
Monoamine Modulation Of Separation-Induced Ultrasonic Vocalizations In Preweanling F344 And Sd Rats, Cynthia Elizabeth Britt
Monoamine Modulation Of Separation-Induced Ultrasonic Vocalizations In Preweanling F344 And Sd Rats, Cynthia Elizabeth Britt
Theses Digitization Project
The purpose of this study was to determine if Fischer 344 (F344) rats, a strain which naturally shows deficits in social communication during adolescence, could be used as a model of the social communication deficits observed in autism. Thus, the goal was to determine if F344 rats would also show fewer emissions of isolated-induced ultrasonic vocalizations (an early onset form of social interaction) as compared to SD rats. Subjects consisted of 142 F344 rat pups (67 male and 75 female). Subjects were treated according to the "Guide for the Care and Use of Mammals in Neuroscience and Behavioral Research" under …
Adolescent And Adult Nicotine Exposure On The Acquisition Of Methamphetamine Self-Administration And The Reinstatement Of Extinguished Methamphetamine-Seeking In Male Rats, Joseph Allan Pipkin
Adolescent And Adult Nicotine Exposure On The Acquisition Of Methamphetamine Self-Administration And The Reinstatement Of Extinguished Methamphetamine-Seeking In Male Rats, Joseph Allan Pipkin
Theses Digitization Project
This study sought to determine the individual and combined contribution of adolescent and adult nicotine exposure on METH self-administration and METH-seeking behavior in male rats. Nicotine is a commonly abused substance among adolescents and is believed to be a "gateway" to other drugs of abuse. In support of the gateway hypothesis, cigarette smoking during adolescence is related to increased methamphetamine (METH) use in adulthood.
Preweanling Exposure To Selective Catecholamine Transporter Inhibitors Differentially Effects Morphine-Induced Antinociception In Adulthood, Joseph Marco Valentine
Preweanling Exposure To Selective Catecholamine Transporter Inhibitors Differentially Effects Morphine-Induced Antinociception In Adulthood, Joseph Marco Valentine
Theses Digitization Project
The purpose of this project is to determine how early methylphenidate exposure alters opioid receptor functioning in adulthood. To this end, we will administer selective monoamine transporter inhibitors for dopamine and norepinephrine (GBR-12904 and atomoxetine) during preweanling period and assess opioid function in adult rats by testing morphine-induced antinociception using the hot-plate and tail-flick tasks. In order to assess the effects of methylphenidate use on brain functions during development, investigations have been conducted in rats using ages roughly analogous to early and late childhood.