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Articles 1 - 6 of 6
Full-Text Articles in Biological Psychology
Cholinergic Basal Forebrain Involvement In The Acquisition Of Differential Reinforcement Of Low Rate Responding Tasks In Rats, Sean Ryan Corley
Cholinergic Basal Forebrain Involvement In The Acquisition Of Differential Reinforcement Of Low Rate Responding Tasks In Rats, Sean Ryan Corley
Theses Digitization Project
It was hypothesized that 192 IgG-saporin lesions of the basal forebrain cholinergic system (BFCS) would disrupt differential reinforcement of low rate (DRL) learning in an uncued DRL task, but would not impair acquisition and performance in the cued version of the task. Results suggest that BFCS lesions impair vigilance to the external cues despite continued practice in the cued DRL, whereas continuous attention to internally produced cues recovers with extended practice in the uncued DRL.
Actions Of A Partial D2-Like Agonist During Low Or High Dopaminergic Tone: A Neurochemical Study Using Preweanling Rats, Shelly Taeko Yoshida
Actions Of A Partial D2-Like Agonist During Low Or High Dopaminergic Tone: A Neurochemical Study Using Preweanling Rats, Shelly Taeko Yoshida
Theses Digitization Project
The neurochemical effects of partial D2-like agonists (i.e., terguride) to alter striatal DOPA accumulation under high and low dopaminergic tone was examined in preweanling rats. The results indicate that terguride has agonist-like (quinpirole-like) effects under a low dopaminergic tone and antagonist-like (haloperidol-like) effects under a high dopaminergic tone during the preweanling period.
192 Igg-Saporin Lesions Of The Nucleus Basalis Magnocellularis Impair Serial Reversal Learning In Rats, Sara Michelle Cabrera
192 Igg-Saporin Lesions Of The Nucleus Basalis Magnocellularis Impair Serial Reversal Learning In Rats, Sara Michelle Cabrera
Theses Digitization Project
In order to assess flexibility in acquiring and using conflicting response rules, rats with selective lesions of the NBM or sham-lesion controls were subjected to serial reversal training in a simple operant discrimination paradigm. The NBM lesion group did not differ from the control group in acquisition of the original rules; the NBM lesion group required more time to master the changes in rules in the first reversal, but not in subsequent reversals.
The Effects Of Neonatal Manganese Exposure On Impulsivity, Unlearned Motoric Function, And Reward, Carmela Marie Reichel
The Effects Of Neonatal Manganese Exposure On Impulsivity, Unlearned Motoric Function, And Reward, Carmela Marie Reichel
Theses Digitization Project
This study examined the effects of low to moderate doses of manganese (0, 250, or 750 _g per day from PD 1-21) on a comprehensive battery of behaviors in rats during the neonatal period, preweanling period, and in adulthood.
The Effect Of Early Psychostimulant Treatment On Abuse Liability And Dopamine Receptors, Steven Wayne Villafranca
The Effect Of Early Psychostimulant Treatment On Abuse Liability And Dopamine Receptors, Steven Wayne Villafranca
Theses Digitization Project
Examines whether the reinforcing properties of drugs of abuse were altered in adulthood by methylphenidate, more commonly known as Ritalin. Subjects were 108 rats of Sprague-Dawley descent (Harlan). Methylphenidate, or saline was administered daily to the subjects from the postnatal period (11-20 days old). The rats preference for morphine during early adulthood was measured using conditioned place preference. The number of dopamine D₂ receptors was measured in each rat and the correlation between receptor number and morphine preference was determined. Results indicate that rats pretreated with methylphenidate showed greater preference for morphine than saline pretreated rats and suggests that exposure …
Effect Of Preweanling Methylphenidate Exposure On The Induction, Extinction And Reinstatement Of Morphine-Induced Conditioned Place Preference In Rats, Kellie Lynn Kucher
Effect Of Preweanling Methylphenidate Exposure On The Induction, Extinction And Reinstatement Of Morphine-Induced Conditioned Place Preference In Rats, Kellie Lynn Kucher
Theses Digitization Project
This study examined the effect of preweanling methyphenidate exposure on later drug reward. We examined the induction, extinction, and reinstatement of morphine induced conditioned place preference (CPP) in rats that received methylphenidate pretreatment during the preweanling period.