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Full-Text Articles in Biological Psychology
192 Igg-Saporin Lesions Of The Nucleus Basalis Magnocellularis Impair Serial Reversal Learning In Rats, Sara Michelle Cabrera
192 Igg-Saporin Lesions Of The Nucleus Basalis Magnocellularis Impair Serial Reversal Learning In Rats, Sara Michelle Cabrera
Theses Digitization Project
In order to assess flexibility in acquiring and using conflicting response rules, rats with selective lesions of the NBM or sham-lesion controls were subjected to serial reversal training in a simple operant discrimination paradigm. The NBM lesion group did not differ from the control group in acquisition of the original rules; the NBM lesion group required more time to master the changes in rules in the first reversal, but not in subsequent reversals.
Cholinergic Basal Forebrain Involvement In The Acquisition Of Differential Reinforcement Of Low Rate Responding Tasks In Rats, Sean Ryan Corley
Cholinergic Basal Forebrain Involvement In The Acquisition Of Differential Reinforcement Of Low Rate Responding Tasks In Rats, Sean Ryan Corley
Theses Digitization Project
It was hypothesized that 192 IgG-saporin lesions of the basal forebrain cholinergic system (BFCS) would disrupt differential reinforcement of low rate (DRL) learning in an uncued DRL task, but would not impair acquisition and performance in the cued version of the task. Results suggest that BFCS lesions impair vigilance to the external cues despite continued practice in the cued DRL, whereas continuous attention to internally produced cues recovers with extended practice in the uncued DRL.