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Articles 1 - 4 of 4
Full-Text Articles in Biological Psychology
Effects Of Atomoxetine On Circadian Rhythms And Locomotor Activity, Rhiannon Ryder Crimmins
Effects Of Atomoxetine On Circadian Rhythms And Locomotor Activity, Rhiannon Ryder Crimmins
Cal Poly Humboldt theses and projects
Background: Attention deficit hyperactivity disorder (ADHD) is a common neurological disorder characterized by inattention, hyperactivity, and impulsive behavior. Many people with ADHD who are taking pharmacological treatments also report having sleep problems, and both children and adults tend to fall asleep later than neurotypical people. Since diagnosis and treatment of ADHD are on the rise, understanding how the disorder and common medications influence circadian rhythms is becoming more important. Zebrafish are a common animal model that have been shown to reliably represent features of many human disorders, including ADHD. Hypothesis: The specific hypotheses tested were: (H1) that a …
Preimplantation Genetic Testing For Neurobehavioral Traits, Peter K. Zeller
Preimplantation Genetic Testing For Neurobehavioral Traits, Peter K. Zeller
Cal Poly Humboldt theses and projects
Differences in behavioral and mental health traits result from unique interactions of genetic and environmental factors. Genetic information has improved along with technological advancements allowing for more data points to be established and increased data resolution. Because of this, there is a greater ability to identify embryos that carry genetic risk. The approach of Preimplantation Genetic Testing (PGT) is routine for certain genetic diseases but has not been widely used for psychiatric or behavioral traits. This paper critically examines the potential application of PGT-P by focusing on one main example, Alzheimer’s disease (AD). AD is the most prevalent form of …
Is The Area Postrema Resistant To The Anesthetic Effects Of Ms-222?, Austin T. Csiszar
Is The Area Postrema Resistant To The Anesthetic Effects Of Ms-222?, Austin T. Csiszar
Cal Poly Humboldt theses and projects
MS-222 is a common fish anesthetic that dampens neural activity by inhibiting neuronal voltage-gated sodium channels (Nav) required for action potentials. Previous experiments conducted by our lab’s primary investigator using fluorescence calcium imaging in zebrafish neurons resulted in the observation that neurons in the area postrema (AP), a circumventricular organ located in the dorsal hindbrain, displayed prominent fluorescence intensity during MS-222 induced sedation. I used the genetically encoded calcium indicator GCaMP6s to conduct fluorescence calcium imaging with the goal of recording neural activity in the larval zebrafish area postrema and optic tectum to compare the anesthetic effects of …
Individual Differences In The Coordinated Behavioral And Physiological Immune Response To Pathogenic Threat, Edwin Joel Rosales-Vijil
Individual Differences In The Coordinated Behavioral And Physiological Immune Response To Pathogenic Threat, Edwin Joel Rosales-Vijil
Cal Poly Humboldt theses and projects
Previous research has shown that simply viewing a pathogenic threat (e.g., a photo of someone sneezing) can trigger our immune systems to activate. Activation of the immune system can be measured through a variety of physiological markers, including inflammatory cells (i.e., cytokines) in the blood or saliva. The current study aims to replicate that finding that viewing pathogen-relevant images will trigger an immune response, and extend this work by investigating whether individual differences in perceived vulnerability to disease impacts the size of this immune response.