Biological Psychology Commons^™

Difficult Turned Easy: Suggestion Renders A Challenging Visual Task Simple, Mathieu Landry, Jason Da Silva Castanheira, Jérôme Sackur, Amir Raz

Psychology Faculty Articles and Research

Suggestions can cause some individuals to miss or disregard existing visual stimuli, but can they infuse sensory input with nonexistent information? Although several prominent theories of hypnotic suggestion propose that mental imagery can change our perceptual experience, data to support this stance remain sparse. The present study addressed this lacuna, showing how suggesting the presence of physically absent, yet critical, visual information transforms an otherwise difficult task into an easy one. Here, we show how adult participants who are highly susceptible to hypnotic suggestion successfully hallucinated visual occluders on top of moving objects. Our findings support the idea that, at …

Assessment Of Dopaminergic And Serotonergic Receptor Antagonists In Male Rats Trained To Discriminate 4-Methylmethcathinone (Mephedrone), Rachel L. Burroughs

Masters Theses

Preclinical drug discrimination studies of the synthetic cathinone, 4-methylmethcathinone (mephedrone) have demonstrated its effects are comparable to those of other popular psychostimulant drugs. Few studies have directly examined the contribution of specific neurotransmitter receptors to mephedrone’s discriminative stimulus effects. The present study investigated the role of dopamine and serotonin receptors in these effects. Eight adult male Sprague-Dawley rats were trained to discriminate 3.0 mg/kg mephedrone from saline. After dose-response curves were determined with mephedrone (0.375-3.0 mg/kg), a series of stimulus antagonism tests were conducted with dopamine antagonists (Sch 23390, haloperidol) and serotonin antagonists (WAY 100,635, MDL 100,907, pirenperone) administered as …

Complex Trauma In Childhood And Its Relationship To Emotion Regulation And Distress Tolerance In College Students, Elizabeth Lombardo

USC Aiken Psychology Theses

Objective: The influence of childhood trauma has been found to be related to difficulties in emotion regulation and distress tolerance in young adulthood (Berenz et al., 2018a, 2018b). Research has shown that childhood abuse and adversities such as neglect or emotional abuse results in impaired processes related to the development of emotion regulation and efficient interpersonal skills, while also resulting in symptoms reflecting disordered affective self-regulation (Cloitre et al., 2009; Shipman, Edwards, Brown, Swisher, & Jennings, 2005; Shipman, Zeman, Penza, & Champion, 2000). Research has examined emotional regulation and distress tolerance in the context of childhood trauma but has not …

Inactivation Of Nucleus Reuniens Impairs Spatial Memory In Mice, Miranda Schwabe

Theses and Dissertations

Episodic memory is a complex process requiring input from several regions of the brain. Coordinated activity in the Dorsal Hippocampus (DH) and medial Prefrontal Cortex (mPFC) is required for episodic memory consolidation. Our laboratory demonstrated that simultaneous subthreshold chemogenetic inactivation of the dorsal hippocampus (DH) and medial prefrontal cortex (mPFC) impairs the consolidation of object placement (OP) and object recognition (OR) memory in female mice (Tuscher et al., 2018), suggesting that these two brain regions work in concert to promote memory consolidation. However, the mechanisms through which the DH and mPFC interact to promote memory consolidation remain poorly understood. A …

Biological Siblings: Can You Trust Them With Your Mate?, Elisha Barron

Electronic Theses, Projects, and Dissertations

Recent studies suggest that genes may influence human mate preferences. What would this mean for same-sex siblings who share genes? Might they also share mate preferences and engage in mate poaching or would social norms and strong sibling bonds discourage such behaviors? We hypothesized that siblings would perceive their mate preferences to be more similar to their sibling’s than to an average person of their same gender. It was also hypothesized that the association between perceived sibling mate preferences and sibling mate poaching would be moderated by sibling closeness and sibling competition. Additionally, it was hypothesized that sibling mate competition …

Chronic Stress In Relation To Locus Of Control, Kendra Clark, Miranda Jany, Carissa Philippi

Undergraduate Research Symposium

Stress is prominent in everyone’s lives, and if the right precautions are not taken, stress can become chronic and harmful to an individual’s health (Schmitz, Neumann, & Oppermann, 2000). To prevent chronic stress, researchers seek to find out important factors that lead to chronic stress. One of the most prominent factors leading to chronic stress is locus of control (LOC), or how much control people feel they have over situations (Cummins, 1988). People can endorse an internal locus of control which means individual attributes events occurring in their life to their own behavior, or an external, which one would consider …

Is Executive Function The Universal Acid?, Stephen J. Morse

All Faculty Scholarship

This essay responds to Hirstein, Sifferd and Fagan’s book, Responsible Brains (MIT Press, 2018), which claims that executive function is the guiding mechanism that supports both responsible agency and the necessity for some excuses. In contrast, I suggest that executive function is not the universal acid and the neuroscience at present contributes almost nothing to the necessary psychological level of explanation and analysis. To the extent neuroscience can be useful, it is virtually entirely dependent on well-validated psychology to correlate with the neuroscientific variables under investigation. The essay considers what executive function is and what the neuroscience adds to our …

Neurodevelopmental Mechanisms Of Adverse Trauma Outcomes In Emerging Adulthood, Olena Kleshchova

Dissertations, Theses, and Capstone Projects

Background: Exposure to traumatic stress and adversity during the formative years of development can have adverse effects on mental health, neuroendocrine stress system function, and the brain, that persist into adulthood. One candidate mechanism that might confer vulnerability to enduring adverse outcomes of early life trauma is disruption of normal brain maturation. As the brain matures, functional interactions among brain regions change until the functional brain architecture (i.e., the functional connectome) reaches a mature state in adulthood. Given that different neural circuits have distinct developmental trajectories and sensitive periods, traumatic stress at a given point in development might have …

Assessing Sex Differences In The Effects Of Short-Term Rem Sleep On Anxiety- And Depressive-Like Behaviors In Rats, Nadia Meshkati

Seton Hall University Dissertations and Theses (ETDs)

Findings from both human and animal studies suggest rapid eye movement (REM) sleep disturbances following a traumatic event can lead to inability to extinguish the fear association, and eventually influence the development of post-traumatic stress disorder (PTSD). Additionally, research has demonstrated that sleep disruptions, including REM sleep deprivation (RSD), increases anxiety- and depressive-like behaviors and states in animals and people, with evidence of sex differences. Furthermore, it has yet to be determined whether short-term RSD, a more natural animal model of PTSD, can influence affective state of subjects. The present study applied short-term RSD to investigate sex differences in the …

Airway Hydrogen Peroxide During A Naturalistic Period Of Sustained Psychological Stress In Individuals With Asthma And Healthy Controls, Chelsey Werchan

Psychology Theses and Dissertations

Reactive oxygen species in the form of exhaled hydrogen peroxide (H₂O₂) and nitric oxide (NO) are important biological markers of inflammation and immune response in the airways of both asthmatics and healthy individuals. Previous research has linked psychological distress to changes in these processes in the airways, which can impact overall disease management outcomes. The current study examined changes in H₂O₂, NO, mood, and other physiological measures during times of prolonged stress using a naturalistic paradigm. Both healthy and asthmatic participants were assessed at three separate time periods; once during a low …

Electrocortical Changes Observed In The N2 As An Outcome Of Attention Bias Modification Training, Hayley Gilbertson

All NMU Master's Theses

Anxiety disorders are currently one of the most predominant mental health conditions worldwide. Increased anxiety is associated with elevated attentional focus to threat also known as attentional bias to threat. Attention Bias Modification (ABM) is a type of computerized training, attempting to reduce attentional focus for threatening stimuli and has been found to successfully reduce symptoms of anxiety. Past studies have implemented ABM training as a possible tool to modulate attention away from threat in attempt to decrease pathological anxiety. The N2 is an event-related potential (ERP) detected in scalp EEG recordings that is associated with conflict monitoring and complex …

Efficacy Of Creative Interventions In Virtual Reality, Matthew Thomas Richesin

Masters Theses

Engaging in creative activities is known to increase well-being by reducing levels of stress, anxiety, and improve life satisfaction. Interventions utilizing creative activities have proven to enhance therapeutic results in various mental disorders. Similarly, virtual reality has emerged as an effective method of decreasing negative aspects of mental disorders. While both creative interventions and virtual reality show promise in enhancing well-being, the efficacy of combining the two has not been explored. This study aimed to combine and compare 2-dimensional and 3-dimensional art-making on stress, anxiety, and mood in a non-clinical college student sample. To accomplish this, both physiological and self-report …

Development Of Prefrontal Structure And Connectivity In Typical Children And Children With Adhd: Association With Language And Executive Function, Dea Garic

FIU Electronic Theses and Dissertations

The structure and connectivity of the prefrontal cortex has been extensively studied for its contribution to language and executive function (EF) development, but many questions still remain whether its microstructural tissue properties can reliably predict behavioral outcomes in very young typically and atypically developing populations. In particular, the bilateral frontal aslant tract (FAT) has garnered increasing interest with respect to its potential association with both language and EF, but has yet to be examined in childhood attention disorders, such Attention Deficit Hyperactivity Disorder (ADHD). At the same time, with advances in diffusion weighted imaging (DWI), new diffusion models offer more …

Neurobiological Mechanisms Of Cognitive Processing Therapy For Post-Traumatic Stress Disorder: A Brain Network Approach, Tessa Vuper

Dissertations

Psychotherapy research is increasingly targeting both psychological and neurobiological mechanisms of therapeutic change. This trend is evident in and applicable to post-traumatic stress disorder (PTSD) treatment research given the high nonresponse rate of individuals with PTSD who undergo cognitive-behavioral therapy (CBT). A review of the literature investigating neurobiological mechanisms of CBT in PTSD reveals inconsistent results that fail to fully support dual process or learning models of CBT effects in the brain. However, network-based models of psychopathology provide a new framework from which to understand both mental disorder symptoms and therapeutic mechanisms. The current study investigated a) whether brain networks …

Scope Of Attention Variation As A Function Of Anxiety And Depression, Kathleen O'Donnell

Electronic Theses, Projects, and Dissertations

As a social species, correct emotional perception is so vital, that the human brain has evolved a mechanism to control attentional choices by exerting a narrowed field of perception during danger, called the scope of attention (SoA). The SoA determines what information will be focused on or ignored by blocking the perception of non-relevant items and increasing selective focus on danger; even if danger is merely a sad-face. The emotional items blocked from perception cannot be remembered because they were never perceived. But, attention-control to emotional stimuli also varies with mood, as seen in mood-disorders. A mood-disorder’s effect upon the …

The Effects Of Low Dose Lysergic Acid Diethylamide Administration In A Rodent Model Of Delay Discounting, Robert J. Kohler

Dissertations

The resurgence of Lysergic Acid Diethylamide (LSD) as a therapeutic tool requires a revival in research, both basic and clinical, to bridge gaps in knowledge left from a previous generation of work. Currently, no study has been published with the intent of establishing optimal microdose concentrations of LSD in an animal model. In the present study, rats were administered a range of LSD doses to quantify potential augmentations in choice behavior in a rodent model of delay discounting. In the first experiment, rats were administered LSD (20 or 40 μg/kg, i.p.) or saline at the start of terminal baseline training …

A Quadratic Analysis Of Trait Anxiety And Heart Rate Variability, Katlyn Schroder

Dissertations, Theses, and Capstone Projects

Trait anxiety refers to an individual’s sensitivity to perceived threat. Though it is not itself diagnosable according to the DSM-5, trait anxiety scales are often administered in a clinical context and serve as an indicator for anxiety disorders. High levels of trait anxiety can result in prolonged periods of intense worry and dysfunction, even in those who are not diagnosed with an anxiety disorder. Previous studies have attempted to understand the relationship between trait anxiety and reactivity of the autonomic nervous system, especially in relation to vagal tone, but have found inconsistent results. One possible explanation for this inconsistency is …

The Biological, Psychological, Cognitive, And Social Perspectives On Aging: The Design Of A Healthy Aging Program For Older Adults, Melissa Santiago

Dissertations

Aging is an inevitable process, accompanied by changes in physiological, cognitive, psychological, and social facets. Researchers have investigated the physiological, cognitive, psychological, and social risk factors associated with aging and have encouraged the use of physical activity, cognitive training, and dietary interventions to alleviate risk factors. However, holistic programs dedicated to promoting successful aging among older adults are uncommon. This review sought to promote successful aging by identifying physiological, cognitive, psychological, and social risk factors that affect older adults and develop a comprehensive program to holistically mitigate these risk factors. Risk factors associated with unsuccessful aging include the development of …

Barriers And Facilitators To Opioid Use Treatment And Recovery Services During Pregnancy, Loralie Woods

Dissertations

Purpose: To identify barriers and facilitators to opioid use treatment and recovery services among pregnant and nonpregnant women who misuse opioids.

Background: Over 130 Americans die daily after overdosing on opioids. Women have not been immune from opioid use disorders (OUDs), with a 4-fold increase from 1999-2010. The prevalence of opioid use among pregnant women increased from 1.5 per 1,000 hospital deliveries to 6.5. Although the annual National Surveys on Drug Use and Health (NSDUH) has provided information on risk factors for OUD related to socioeconomic and demographic factors, no studies using this data have identified barriers to opioid use …

The Effects Of Activity-Based Anorexia On The Rewarding Properties Of Methamphetamine And Wheel Running, Rachael M. Langa

Theses and Dissertations

An activity-based anorexia (ABA) paradigm in adolescent female mice was used to explore whether anorexia affects circuits underlying reward. The ABA paradigm significantly enhanced methamphetamine-induced conditioned place preference (CPP), but not wheel-induced CPP. These results indicate that the ABA paradigm enhances the rewarding properties of methamphetamine, but not wheel running.

Student Beliefs About What Factors Influence Their Gpa, Emma R. Denelsbeck

Senior Honors Projects, 2020-current

There are many different factors that contribute to grade point averages (GPAs) in college. Students may attribute their academic performance and GPAs to any number of different variables such as stress levels, sleep quality and alcohol use. The current study investigated what students believed had an effect on their GPA, and if these differed based on concussion history. This study examined if students thought that concussions affected their GPA. Participants were University students who completed an online survey consisting of the Texas Evaluation of Concussion History (TECH), and the Depression, Anxiety, and Stress Scale (DASS-21). The results of a Mann-Whitney …

The Effects Of Antibiotics And Probiotics On Memory And Depression Across Age Groups, Amanda Powell

Masters Theses, 2020-current

The gut-brain axis is a bidirectional pathway that acts as a connection between the gut and the brain. Bacterial changes in the gut alter this pathway, affecting organism’s health, cognition, and behavior. Commensal bacteria in the gut can reduce inflammation and increase longevity while pathogenic bacteria can have opposite effects. Reduced commensal gut bacteria can result in an increase in stress activation, depression, and anxiety in both human and animal models. Increases in commensal bacteria and decreases in pathobiontic bacteria can decrease hypothalamic pituitary adrenal (HPA) system activation, anxious behavior, and depressive behavior. Alternatively, increases in pathobionts can lead to …

Cognitive Behavioral Therapy For Comorbid Posttraumatic Stress Disorder, Traumatic Brain Injury, And Associated Sleep Disturbances, Aubretia D. Snyder

Intuition: The BYU Undergraduate Journal of Psychology

With an increasing number of veterans returning from combat with significant head injuries, research interests have begun to turn to the neuropsychological relationship between traumatic brain injury and posttraumatic stress disorder. Research has found that these dysfunctions often occur together and that both disorders may cause an exacerbation of symptoms in one another. This relationship may be negatively affected further by the presence of sleep disturbances. The complexity of this relationship requires extra consideration in regards to treatment, and cognitive behavioral therapy may be effective in treating this comorbid condition. This paper discusses the functional relationship of posttraumatic stress disorder …

The Spectral Nature Of Anxiety Disorders: Examining Similarities In Clinical And Subclinical Populations, Alexandra M. Muir

Intuition: The BYU Undergraduate Journal of Psychology

Generalized Anxiety Disorder (GAD) is one of the leading mental illnesses in the United States today (Alvarez et al., 2012). However, a large number of individuals have their lives disrupted by the symptoms of anxiety, but their symptoms are not severe enough to be diagnosed with GAD. These individuals, much like individuals with GAD, have high trait anxiety, differential brain structure and function, and hypervigilant performance monitoring. Further understanding the neural correlates related to subclinical generalized anxiety disorder and how the neural mechanisms involved relate to daily functioning is of utmost importance. Since there are individuals suffering from subclinical anxiety …

The Relationship Of Executive Function And Alpha Band Activity During The Eriksen Flanker Task: An Eeg Study, Destiny A. Willis

USC Aiken Psychology Theses

Objective: Neural frequencies, measured by electroencephalogram, can be indicative of certain cognitive states. One oscillation, called the alpha wave, has become a proxy for the cognitive ability related to attention. Research suggests that anxiety may result in atypical alpha oscillations when engaging in an attention task, thereby also resulting in potentially dysfunctional attentional abilities. The current study aimed to investigate the relationship between alpha wave frequency, executive function, trait anxiety symptoms, depressive symptoms, and response selection.

Method: The Eriksen flanker task was used to measure response selection, while an electroencephalogram recorded alpha brainwave activity (N = 47). This study incorporated …

The Role Of Dopamine In Decision Making Processes In Drosophila Melanogaster, Michelle C. Bowers

Undergraduate Honors Theses

Understanding the neural processes that mediate decision making is a relatively new field of investigation in the scientific community. With the ultimate goal of understanding how humans decide between one path and another, simpler models such as Drosophila Melanogaster, the common fruit fly, are often utilized as a way of determining the neural circuits involved in these decision-making processes. One of the most important decisions flies make is the decision of where to lay their eggs (oviposit). Choosing the proper substrate upon which to lay eggs is a crucial decision that can ultimately impact their fecundity. This paper investigates the …

Differential Patterns Of Theta Activation Underlying Various Cognitive Control Strategies, Jarrod Eisma

Biomedical Engineering Undergraduate Honors Theses

In this study, EEG was recorded from 157 participants at the University of Arkansas as they performed three computer tasks that tested inhibitory control (Go/Nogo Task), proactive and reactive control (AX-Continuous Performance Task), and resolving response conflict (Global/Local Task- modified Flanker Task). Time-frequency analysis (ERSP) was the primary focus of this study, in order to take advantage of the temporal and frequential characteristics of EEG recordings. The ERSPs and following statistical analysis showed significantly higher midfrontal theta band (4-8 Hz) power values for target trials (those that required more cognitive control) than control trials, which indicated that the procedure was …

Regional Differences In Wild North American River Otter (Lontra Canadensis) Behavior And Communication, Sarah Walkley

Dissertations

This study focuses on the vocalization repertoires of wild North American river otters (Lontra canadensis) in New York and California. Although they are the same species, these two established populations of river otters are separated by a significant distance and are distinct from one another. River otters are semi-aquatic social predators that can be found throughout North America. This is the first study to examine the vocalizations of wild river otters, and results are compared across field sites in the different regions. River otter vocalizations and behaviors in New York were recorded using Bushnell Aggressor trail cameras that …

Interactive Effect Of Maternal Activation And Disc-1 Knockout On Pup Preference Of Postpartum Rats, Barbara Bueno

UCARE Research Products

The main purpose of the study was to find a three-way interaction between genotype, treatment and interacted subjects. Interestingly, and not expected, the KO*MIA rats spent more time with the pups compared to time spent with the male rat. This unexpected results from this study are evidence that there is a complex spectrum of behavioral symptoms due to genetics, environment and their interactive effect (Schwartzer et aI., 2013). For that reason, the interaction between genetics (DISCI) and environment (MIA) might be more complex than what is believed.

Sedative And Neurotoxic Properties Of Brexanolone Compared To Midazolam In The Developing Rodent Brain, Jacob Huffman

Dissertations

The developing brain is susceptible to extensive neurotoxicity following exposure to sedative/anesthetic drugs (SADs). Every year hundreds of thousands of children around the world are exposed to SADs with no viable non-neurotoxic agents approved for clinical use. Allopregnanolone (AlloP) has well-established sedative effects in adults and neonates. AlloP and many SADs produce sedation/anesthesia through allosteric modulation of GABA_A receptors, which is one of two principal mechanisms behind SAD-induced neurotoxicity. Evidence suggests AlloP has the unique capacity to regulate key apoptotic factors in adults and is widely involved with critical stages of neurodevelopment, indicating this neurosteroid might serve as a …