Biological Psychology Commons^™

Caffeine Withdrawal And Dependence: A Review, Alexander Roberts

Williams Honors College, Honors Research Projects

With the prevalence of caffeine use increasing in modern lifestyles, it is important to look at the symptoms of caffeine use, including withdrawal and dependence, and whether these symptoms have implications for addiction. A limited number of assessments have been developed to assess caffeine withdrawal. In order to make a call for more assessments and programs to be developed to assist with healthy caffeine use, this literature review observed recent studies focusing on withdrawal and dependence. Ozsunger et al. (2009) classified caffeine withdrawal into three categories of symptoms. Three years later, Juliano et al. (2012) used an experimental approach to …

Neurocorrelates Of The Mirror Neuron System In Children With Chromosome 22q11.2 Deletion Syndrome, Ade Marais

University of New Orleans Theses and Dissertations

Activation of brain regions that make up the mirror neuron system (MNS) is thought to reflect processing and perceiving behavior, action, and intentionality of other organisms. Sensing and perceiving motor behavior in others is an important component of understanding and participating in social interactions. Children with chromosome 22q11.2 deletion syndrome (22q11.2DS) are diagnosed with serious medical, cognitive, and socio-emotional symptoms. Atypical development and function of the MNS may underpin some aspects of socio-emotional impairment and autism spectrum disorder (ASD)-like symptomology reported. This study of the MNS investigates differences in activation in the operculum, sensorimotor areas, and basal ganglia (BG) in …

Possible Breakdown Of Dopamine Receptor Synergism In A Mouse Model Of Huntington's Disease, Samantha F. Kennedy

University of New Orleans Theses and Dissertations

The model of basal ganglia function proposed by Albin, Young and Penney (1989) describes two anatomically independent motor pathways, the direct and indirect. However, under normal conditions striatal dopamine (DA) is required for the expression of motor behavior, and DAergic control of the two pathways (via D1 and D2 receptors, respectively) is dependent on co-activation. We tested for a possible breakdown of D1/D2 synergism using transgenic R6/1 mice bearing the human huntingtin allele (Htt). Motor stereotypy, observed prior to the onset of HD-related symptoms, was rated on a 5-point scale following activation of: A) D1 receptors alone, B) D2 receptors …

Do Flashbulb Memories Transmit Across Generations? 9/11 As A Case Study, Shanique Meyler

Student Theses

Psychologists have only recently begun to examine the extent to which personal memories transmit across generations. When they have, they typically focus on family stories (see Merrill & Fivush, 2016) or memories of historical events (Svob & Brown, 2012). The present study extends this line of research to flashbulb memories, or memories of an individual’s circumstances when first learning about a consequential, historical event (Brown & Kulik, 1977). To this end, the present study examines the extent to which flashbulb memories surrounding the events of the terrorist attacks on 9/11 transmit to the next generation. The results suggest that flashbulb …

Effects Of Nicotine Exposure On Methamphetamine Oral Self-Administration, Extinction, And Reinstatement In Adolescent Rats, Zachary Robert Harmony

Electronic Theses, Projects, and Dissertations

Adolescence is a vulnerable developmental period in regards to drug initiation and use. The gateway hypothesis suggests that adolescent cigarette smoking may result in a heightened risk for methamphetamine use. However, little is understood about the role of nicotine on adolescent methamphetamine addiction. The aim of the present study was to determine whether early, late, or continuous adolescent nicotine exposure would alter oral methamphetamine self-administration, extinction, or reinstatement. A total of 164 male and female Sprague-Dawley rats were pretreated with saline or nicotine (0.16, or 0.64 mg/kg, sc) beginning on postnatal day (PD) 25 for 10 consecutive days. On PD …

Preschool Executive Function Predicts Childhood Resting State Functional Connectivity And Adhd And Depression, Elizabeth Hawkey

Arts & Sciences Electronic Theses and Dissertations

Background: Measures of executive function (EF), such as the Behavior Rating Inventory of Executive Function, distinguish children with Attention-Deficit/Hyperactivity Disorder (ADHD) from control children, but less work has examined relationships to depression or brain network organization. This study examined whether early childhood EF predicted a new onset or worsening of ADHD and/or depression, and examined how early childhood EF related to functional connectivity of brain networks at school age. Methods: Participants were 247 children, enrolled at ages 3-6, from a prospective study of emotion development. The BRIEF Global Executive Composite (BRIEF-GEC) was used as the measure of EF in early …

Contributions Of Appetitive And Aversive Motivational Systems To Decision-Making, Heather E. Soder

USF Tampa Graduate Theses and Dissertations

Optimal decision-making entails outcome evaluation, comparing received costs and benefits with predicted costs and benefits. The anterior cingulate cortex (ACC), a brain area with major connections to the appetitive and aversive motivation systems, may provide the neural substrate of this evaluation process. One way to measure the relative contribution of these systems on decision-making is to measure individual differences in risk-taking behaviors. For individuals who make risky choices, this evaluation step may be biased: some show a preference for immediate, short-term rewards (increased appetitive system), while devaluing the long-term consequences of their choices (decreased aversive system). However, most studies supporting …

Volition And Action In The Human Brain: Processes, Pathologies, And Reasons, Itzhak Fried, Patrick Haggard, Biyu J. He, Aaron Schurger

Psychology Faculty Articles and Research

Humans seem to decide for themselves what to do, and when to do it. This distinctive capacity may emerge from an ability, shared with other animals, to make decisions for action that are related to future goals, or at least free from the constraints of immediate environmental inputs. Studying such volitional acts proves a major challenge for neuroscience. This review highlights key mechanisms in the generation of voluntary, as opposed to stimulus-driven actions, and highlights three issues. The first part focuses on the apparent spontaneity of voluntary action. The second part focuses on one of the most distinctive, but elusive, …

The Effects Of Sports Related Head Impact On Balance And Neurocognitive Functions, Shaquanda D. Ross-Simmons, Michelle L. Vieyra, Abhishek Jain, Keri Weed

Journal of the South Carolina Academy of Science

The goal of this study was to investigate the effects of sports-related head injury on balance, attention, and memory. Reliable differences have been found using measures that directly tap into brain functioning, such as the auditory oddball task combined with EEG recording. We hypothesized that athletes reporting a diagnosed concussion or participation in high-risk sports would have compromised balance and neurocognitive functioning compared to athletes in low risk sports. Forty-five undergraduate participants were identified as either concussed, non-concussed in high-risk sports, or non-concussed in low-risk sports using a survey of athletic history, head trauma and demographics. The Biopac MP36 system, …

Mediators And Moderators Of Childhood Family Adversity And Adult Cortisol Response: The Role Of Marital Conflict Behavior, Jeffrey P. Winer

Doctoral Dissertations

Childhood family adversity influences behavioral and physiological response processes to acute interpersonal stress. Additionally, conflict behaviors in marriage are primary determinants of stress response and related psychological problems in adulthood. As little research has examined these two important literatures simultaneously, further work is warranted to clarify the role of marital conflict behavior in the relation between childhood family adversity and adult cortisol response to conflict. The current study examined relations between childhood family adversity, observed marital conflict behaviors, and salivary cortisol in response to acute marital conflict among 228 different-sex newlywed couples. We examined intrapersonal “actor” effects as candidate mediators …

The Effect Of Text Color And Text Grouping On Attention And Short Term Recall Memory, Emily Haynes

Honors College Research

This study sought to discover whether there was a connection between the attentional draw of a word, as represented by text color and grouping, and the likelihood of it being transferred into short term recall memory. College students at Harding University in Searcy, Arkansas were given one of six timed memory test scenarios and asked to recreate the list to the best of their ability. The students were then asked to complete a series of post-test questions designed to measure their perception of their own performance on the test. The students were also asked to complete a demographics questionnaire that …

Entrainment Of Voluntary Movement To Undetected Auditory Regularities, Aaron Schurger, Nathan Faivre, Leila Cammoun, Bianca Trovó, Olaf Blanke

Psychology Faculty Articles and Research

In physics “entrainment” refers to the synchronization of two coupled oscillators with similar fundamental frequencies. In behavioral science, entrainment refers to the tendency of humans to synchronize their movements with rhythmic stimuli. Here, we asked whether human subjects performing a tapping task would entrain their tapping to an undetected auditory rhythm surreptitiously introduced in the guise of ambient background noise in the room. Subjects performed two different tasks, one in which they tapped their finger at a steady rate of their own choosing and one in which they performed a single abrupt finger tap on each trial after a delay …

The Neural Mechanisms Underlying The Perception And Production Of Learned Vocalizations In Songbirds, Shannon Katie Mischler

Electronic Thesis and Dissertation Repository

Songbirds produce a wide array of vocalizations, including song, and learned and innate calls. Songs and calls can be functionally defined. Songs are typically used to attract potential mates and defend one’s territory, whereas calls are used for everything else, such as advertising the presence of a predator, or location of a food source, and maintaining contact with members of one’s flock. The purpose of this thesis was to better understand the neural mechanisms underlying call production and perception in two songbird species; the black-capped chickadee (Poecile atricapillus) and the zebra finch (Taeniopygia guttata). My objectives …

Why Do We Care?: A Natural History Of Noddings’ Ethical Theory, Walter Jason Niedermeyer

Between the Species

Noddings’ theory of caring, which is nearing its 35^th anniversary, has failed to garner the attention of the more classical theories of ethics. This slight may be due to its relative youth, or the historical support for other constructs, but if examined through the lens of evolutionary biology, the validity of Noddings might be tested. Using recent discoveries from the emerging fields of cognitive ethology and neuroscience, I have evaluated whether there exists evolutionary underpinnings for her theory. My analysis makes it apparent that the empathy and altruism required for the practice of caring are as much a product …

The Role Of Glutamate Neurotransmission In The Ventral Tegmental Area In The Expression Of Conditioned Approach Learning, Priscila Hachimine-Merli

Dissertations, Theses, and Capstone Projects

Conditioned stimuli (CSs) come to function as CSs by acquiring the capacity to activate the same mesocorticolimbic dopamine (DA) neurons activated by primary rewards, producing conditioned activation of these neurons and their associated motivational states. This model stipulates that CSs activate mesocorticolimbic DA systems through the activation of glutamate receptors on DA neurons in the ventral tegmental area (VTA). We tested the hypothesis that glutamate receptor stimulation in the VTA is necessary for the expression of conditioned approach. Rats were tested in a conditioned approach protocol that consisted of 7 consecutive conditioning sessions (light presentations and food were paired), one …

Selfie-Takers Prefer Left Cheeks: Converging Evidence From The (Extended) Selfiecity Database, Lev Manovich, Vera Ferrari, Nicola Bruno

Publications and Research

According to previous reports, selfie takers in widely different cultural contexts prefer poses showing the left cheek more than the right cheek. This posing bias may be interpreted as evidence for a right-hemispheric specialization for the expression of facial emotions. However, earlier studies analyzed selfie poses as categorized by human raters, which raises methodological issues in relation to the distinction between frontal and three-quarter poses. Here, we provide converging evidence by analyzing the (extended) selfiecity database which includes automatic assessments of head rotation and of emotional expression. We confirm a culture- and sex-independent left-cheek bias and report stronger expression of …

Understanding The Role Of The Ventrolateral Prefrontal Cortex In Emotional Memory Using Transcranial Direct Current Stimulation And Transcranial Magnetic Stimulation, R. Rachel Weintraub-Brevda

Dissertations, Theses, and Capstone Projects

Emotional stimuli can have both beneficial and detrimental effects on memory, such that emotional stimuli can be distracting from current neutral working memory goals, while also leading to enhanced episodic memory for the distracting emotional stimuli. Recent evidence suggests that the ventrolateral prefrontal cortex (VLPFC) has multiple roles in the enhancing effects of emotion on memory through top-down/controlled processes, including 1) coping with negative distraction and 2) elaborative encoding of negative information. Additionally, previous research has alluded to hemispheric differences in the VLPFC (Chapter 1). However, previous research has been correlational, with no strong laterality tests of the VLPFC. Two …

Roles Of Gabab, Muscarinic And Nicotinic Receptor Signaling In The Acquisition And Expression Of Fructose And Fat-Conditioned Flavor Preferences And Acquisition Of Quinine-Conditioned Flavor Avoidances In Rats, Francis M. Rotella

Dissertations, Theses, and Capstone Projects

In addition to increased intake of sweet solutions by mammals, learning, particularly classically-conditioned “Pavlovian-like” learning, also plays an important role. An orosensory conditioned flavor preference (CFP) can be elicited by pairing one novel flavor (conditioned stimulus, CS+) with a fructose solution and a second novel flavor (CS-) with a saccharin solution. Rats will prefer the CS+ flavor in a subsequent 2-bottle choice test with both flavors mixed in saccharin. Previous pharmacological analyses revealed that systemic administration of dopamine (DA) D1 and D2 as well as NMDA, but not opioid, receptor antagonists eliminated the acquisition (learning) of fructose-CFP. Further, expression of …

The Nucleus Accumbens Core Dopamine D1 And Glutamate Ampa/Nmda Receptors Play A Transient Role In The Performance Of Pavlovian Approach Behavior, Veronica Dobrovitsky

Dissertations, Theses, and Capstone Projects

The role of the nucleus accumbens core (NAc core) continues to be redefined with newly acquired data on neurochemical mechanisms mediating the learning and performance of behavior. Previous empirical data showed that dopamine transmission at the D1 receptor (D1R) plays a transient role in the expression of learned Pavlovian approach behavior. Here we show that, prior to overtraining, dopamine activity at D1Rs specifically within the NAc core is critical for the performance of approach behavior elicited by the recently-acquired reward-paired cue. Blockade of D1Rs in the NAc core, but not the dorsomedial striatum or NAc shell, disrupted approach responses during …

Activation And Habituation Of The Cingulate Cortex During Emotion Processing In Healthy Controls, Borderline, And Schizotypal Personality Disorder, Emily Balevich

Dissertations, Theses, and Capstone Projects

Disturbances in emotional functioning are central features of the clinical profiles of both borderline and schizotypal personality disorder (BPD and SPD, respectively). BPD is characterized by a high sensitivity to emotional stimuli and unusually strong and long-lasting reactions, indicative of impaired habituation to emotional stimuli (Linehan, 1993). Previous research suggests that SPD patients demonstrate limbic hyper-reactivity to unpleasant stimuli, at least initially, but intact habituation to repeated presentation of unpleasant stimuli (Hazlett et al., 2012). The cingulate cortex supports various aspects of emotion processing and regulation, and abnormalities of this region have been related to emotion dysfunction in SPD and …

Rumination Is Associated With Diminished Performance Monitoring, Ema Tanovic, Greg Hajack, Charles A. Sanislow

Charles A. Sanislow, Ph.D.

The Effects Of Intranasal Orexin-A On Mk-801-Induced Attentional Deficits: Addressing Cognitive Impairment In An Nmda Receptor Hypofunction Model Of Schizophrenia, Eden Blake-Lea Maness

Dissertations, Theses, and Masters Projects

Schizophrenia (SZ) is a debilitating condition wherein those afflicted experience positive symptoms, including hallucinations and delusions, as well as negative symptoms, including alterations of processing affecting cognition and social interactions. The NMDA receptor hypofunction model of SZ asserts that a reduction in hippocampal NMDA receptor input produces the pathology of this disorder, promoting excessive frontocortical excitatory neurotransmission – particularly overstimulation of basal forebrain cholinergic neurons – that ultimately impairs cognitive and sensorimotor processes. Orexin-A (OxA), a neuropeptide principally involved in wakefulness and appetitive behaviors, has been shown to demonstrate cognitive-enhancing qualities in models of psychiatric and neurodegenerative illness. In the …

Methamphetamine-Induced Conditioned Place Preference In Adolescent Male And Female Mice Of Two Strains, Andre Bevil Toussaint

Theses and Dissertations

We used a conditioned place preference paradigm to test the rewarding effects of methamphetamine (1mg/kg) in adolescent male and female mice of two strains. We found that methamphetamine induced conditioned place preference in female C57Bl/6 and male 129/SvEv mice, but not female 129/SvEv or male C57Bl/6 mice.

A Diffusion Tensor Imaging Study Of Motor Fibre Path Integrity And Overt Responsiveness In Disorders Of Consciousness, Clara A. Stafford

Electronic Thesis and Dissertation Repository

This study investigated the relationship between motor thalamo-cortico-cerebellar fibre path integrity and overt responsiveness in patients with disorders of consciousness (DOC). Additionally, we investigated the potential of imaging these motor tracts at ultra-high fields. Study I and II aimed to map the white matter connections of motor execution fibres in DOC patients. Our results showed significant reductions in motor fibre path integrity across DOC diagnostic categories. Study III and IV aimed to develop a 7T MRI Diffusion Tensor Imaging (DTI) sequence. We optimized this sequence to image motor fibre paths in DOC patients. We concluded that, in healthy controls, probabilistic …

Designing An Authentic Behavioral Research Experience In The Classroom Using Siamese Fighting Fish, Betta Splendens, Gianne Souza, Ronald M. Coleman

STAR Program Research Presentations

Recently there have been major shifts in biology education towards emphasizing the teaching of the scientific process to more closely reflect actual scientific practices. Authentic research experiences require the development of many higher order cognitive skills. Creating an authentic research experience that appropriately scaffolds the development of these complex skills while engaging individual student motivation remains challenging in classroom settings. Some common challenges include limited time available for working with large numbers of students, cramped working areas, and limited funding and materials resources. Using the Siamese Fighting Fish, Betta splendens, we have created an economically viable authentic animal behavioral …

Effects Of Self-Affirmation On Emotion And Cardiovascular Responses, Wei-Ju Chen

Theses and Dissertations

Self-affirmation is the act of focusing on important aspects of the self, such as personal values and characteristic. Benefits of self-affirmation have been documented in past research. However, the immediate impacts of self-affirmation on cardiovascular responses have not been fully explored. Therefore, the present study examined such effects both during and consequent to the practice of self-affirmation. One hundred and twenty-five participants completed the study. A within-subject design was used, in which each participant went through both the control and self-affirmation conditions (the order of presentation was counterbalanced). In the self-affirmation condition, participants were asked to write about their top-ranked …

Evaluating The Use Of Self-Relevant Stimuli In Attention Bias Modification Training As A Treatment For Anxiety: A Near-Infrared Spectroscopy Study, Jacob Scott Aday

All NMU Master's Theses

Increased attentional bias to threat has been identified as a causal mechanism in the development of anxiety. As such, attention bias modification (ABM) was conceived as a treatment option where anxiety is alleviated through a computerized cognitive training regimen that reduces an individual’s attentional bias to threat. However, few studies to date have examined how to tailor ABM treatments to unique individuals and how that may facilitate greater generalization of treatment effects in the real world. Additionally, the neural mechanisms underlying ABM are poorly understood. The participants in this study gave a list of the 10 things that caused them …

Emotion Dysregulation And Functional Connectivity In Children With And Without A History Of Major Depressive Disorder, Katherine Lopez

Arts & Sciences Electronic Theses and Dissertations

Recent interest has emerged in understanding the neural mechanisms by which deficits in emotion regulation (ER) may relate to the development of depression. Cortico-limbic alterations reported in emotion dysregulation and depression may be one possible link. We examined the relationships between emotion dysregulation in school age, corticolimbic resting state functional connectivity (rs-FC) in preadolescence, and depressive symptoms in adolescence. Participants were 143 children from a longitudinal preschool onset depression study who completed the Children Sadness Management Scale (CSMS), Child Depression Inventory (CDI), and two resting state MRI scans. We examined rs-FC between four primary regions of interest (ROIs; bilateral dorsolateral …

Cumulative Trauma, Emotion Reactivity And Salivary Cytokine Response Following Acute Stress Among Healthy Women., Yvette Z. Szabo

Electronic Theses and Dissertations

This study furthers understanding of how trauma exposure may be connected to the development and maintenance of poor health by focusing on cytokines, tightly regulated proteins of the immune system. Cytokine responses to acute stress have been associated with the onset of poorer mental health in physically healthy women. The present study examined how two factors recently associated with cytokine reactivity –cumulative trauma and emotion reactivity– are associated with salivary cytokine reactivity among healthy women. Seventy-one women, screened to be physically and mentally healthy, completed a laboratory acute stress paradigm and self-report measures of state emotion and trauma exposure. Participants …

An Investigation Of The Neural Components And Saccade Sequences That Enable Direct Navigation Through Virtual Space, Daniel R. Barto

Psychology ETDs

Spatial navigation is a critical behavior for nearly all life forms. The ability to navigate to a destination and to remember how to return to that destination involves numerous brain processes such as perception, attention, memory, learning, proprioception, and distance estimation. The study of spatial navigation, in various organisms and on different sorts of maze-apparatuses, has revealed what is required of the brain and what is required of the environment to enable successful navigation. This dissertation adds to this vast literature by examining the physiological and behavioral components involved in human navigation in a virtual environment.

The primary aim of …