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Full-Text Articles in Biological Psychology
Competitive And Facilitative Interactions Between Pavlovian Cues In Human Associative Learning: A Behavioral And Neural Analysis, Fahd Alhazmi
Dissertations, Theses, and Capstone Projects
Learning to anticipate significant events accurately is a crucial element of survival for all species. The process by which animals acquire this knowledge has been a central question of psychological research. A fundamental assumption of many learning theories is that the predictive value assigned to cues is not simply determined by their probability of reinforcement but rather by their ability to compete with other cues present during learning. The assumption of cue competition has significantly contributed to the development of behavioral and neuroscience research for decades, as it has opened the door to new empirical and theoretical advances on the …
Investigating Anxiety-Like Behavior As A Non-Motor Side Effect Of Deep Brain Stimulation Of The Subthalamic Nucleus In A Parkinsonian Rat Model, Carter Mulder
All Graduate Theses, Dissertations, and Other Capstone Projects
Parkinson’s disease (PD) is estimated to impact nearly 10 million people globally and is estimated to increase in the future. PD is a progressive neurodegenerative disease that worsens through continuous cell death of dopaminergic neurons. This cell death can create motor symptoms such as bradykinesia, tremor, and muscular rigidity. Subthalamic nucleus deep brain stimulation, STN DBS, is a surgical intervention which places stimulating electrodes in the STN greatly improving motor symptoms. However, STN DBS has been reported to possibly influence non-motor symptoms such as anxiety both acutely and long-term, which decreases the quality of life for those with PD. We …
Cerebellum-Seeded Functional Connectivity Changes In Trait-Anxious Individuals Undergoing Attention Bias Modification Training, Katherine Elwell
Cerebellum-Seeded Functional Connectivity Changes In Trait-Anxious Individuals Undergoing Attention Bias Modification Training, Katherine Elwell
All NMU Master's Theses
Anxiety and anxiety related disorders are increasing at a drastic rate in the past decade, with the NIMH reporting that 31.1% of U.S. adults will experience an anxiety disorder at some point in their lives. Anxiety is commonly characterized by increased attention bias to threat. Attention Bias Modification (ABM) is a new treatment used to reduce individual’s attention bias towards threat. The extent to which ABM leads to underlying neural changes is still unknown. The cerebellum is a neglected brain structure, with new research provides evidence that cerebellum’s functional connectivity and shared networks with threat processing regions has a direct …
Learning To Feel Safe: A Translational Study Of The Influence Of Safety Learning On Anxiety-Related Overgeneralized Fear, Hyein Cho
Dissertations, Theses, and Capstone Projects
Anxiety disorders are among the most common mental health diagnoses, affecting about a third of the population in their lifetime. However, approximately a third of individuals with anxiety do not respond to current treatment approaches, highlighting the need to identify additional potential therapeutic mechanisms. Safety learning is one such mechanism, but methodological challenges and a dearth of research have prevented the field from advancing the understanding of the role of safety learning in the etiology and remediation of anxiety disorders. Animal research, using single-cued safety learning paradigms, has yielded promising early findings, demonstrating that safety learning directly reduces anxiety-related behaviors …
Influences Of Salvinorin A And Sex Differences On Depressive- And Anxiety-Like Behaviors In A Chronic Mild Stress Paradigm, Sarah Mitchell
Influences Of Salvinorin A And Sex Differences On Depressive- And Anxiety-Like Behaviors In A Chronic Mild Stress Paradigm, Sarah Mitchell
Theses
Kappa opioid receptors are colocalized with dopamine receptors and are frequently associated with depression, anxiety, stress, and drug use and abuse. KOR antagonism has widely been considered anti-depressive and anxiolytic in animal models while agonism is pro-depressive and anxiogenic. However, recent findings suggest that SalvA, a natural kappa agonist derived from a plant in the mint family, can reduce depressive- and anxiety-like behavior in rats. The current study investigated the effects of chronic mild stress on behavior, attenuation by SalvA, and sex differences. 52 Long-Evans rats, 26 males and 26 females, were exposed to six weeks of CMS. Animals received …
Anxiety-Like Behaviors And C-Fos Expression In Adult Zebrafish: Effects Of Housing Conditions, Alcohol And Caffeine, Adam Douglas Collier
Anxiety-Like Behaviors And C-Fos Expression In Adult Zebrafish: Effects Of Housing Conditions, Alcohol And Caffeine, Adam Douglas Collier
Dissertations
Alcohol abuse is the third largest risk factor for disease world, responsible for an estimated 3.3 million deaths each year. The concomitant ingestion of alcohol and caffeine is hypothesized to increase risk factors associated with alcohol use alone by reducing subjective effects of intoxication. The zebrafish (Danio rerio) has recently garnered attention from researchers as an effective pre-clinical in-vivo animal model in behavioral pharmacology research, largely due to small size, low-cost and ease of drug delivery. A number of studies have reported the effects of alcohol and caffeine on zebrafish behavior at a variety of doses. However, the …
Working Memory Impairments In Chromosome 22q11.2 Deletion Syndrome: The Roles Of Anxiety And Stress Physiology, Ashley F. P. Sanders
Working Memory Impairments In Chromosome 22q11.2 Deletion Syndrome: The Roles Of Anxiety And Stress Physiology, Ashley F. P. Sanders
University of New Orleans Theses and Dissertations
Stress and anxiety negatively impact the working memory system by competing for executive resources. Broad memory deficits have been reported in individuals with chromosome 22q11.2 deletion syndrome (22q11.2DS). We investigated anxiety and physiological stress reactivity in relation to visuospatial working memory impairments in 20 children with 22q11.2DS and 32 typically developing children (M = 11.10 years, SD = 2.95). Results indicate reduced post-stress RSA recovery and overall increased levels of cortisol in children with 22q11.2DS. Additionally, anxiety mediated the relationship between 22q11.2DS and visuospatial working memory impairment. However, there was no indication that stress response physiology mediated this association. …