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Full-Text Articles in Biological Psychology

Perseverance: Psychospiritual And Genetic Perspectives, Tony N. Jelsma, Arielle Johnston, Bruce Vermeer Jul 2016

Perseverance: Psychospiritual And Genetic Perspectives, Tony N. Jelsma, Arielle Johnston, Bruce Vermeer

Faculty Work Comprehensive List

Perseverance constitutes a quality that motivates humankind to press onward usually in the face of significant adversity and resistance. Perseverance is also important in the Christian life. The apostle Paul, using athletic training metaphors, frequently urges his readers to persevere in the faith, even describing his own life as a fight and a race (2 Tim.4:7). Yet, certain groups of people seem to possess a greater measure of perseverance than others have. We are therefore led to ask, “Can our ability to persevere be, in God’s providence, at least partly genetically influenced?”


The Contribution Of The Pineal Gland On Daily Rhythms And Masking In Diurnal Grass Rats, Arvicanthis Niloticus, Dorela D. Shuboni, Amna A. Agha, Thomas K. H. Groves, Andrew J. Gall Jul 2016

The Contribution Of The Pineal Gland On Daily Rhythms And Masking In Diurnal Grass Rats, Arvicanthis Niloticus, Dorela D. Shuboni, Amna A. Agha, Thomas K. H. Groves, Andrew J. Gall

Faculty Publications

Melatonin is a hormone rhythmically secreted at night by the pineal gland in vertebrates. In diurnal mammals, melatonin is present during the inactive phase of the rest/activity cycle, and in primates it directly facilitates sleep and decreases body temperature. However, the role of the pineal gland for the promotion of sleep at night has not yet been studied in non-primate diurnal mammalian species. Here, the authors directly examined the hypothesis that the pineal gland contributes to diurnality in Nile grass rats by decreasing activity and increasing sleep at night, and that this could occur via effects on circadian mechanisms or …


Examination Of Methamphetamine Reinstatement In Female And Male Rats: A Pre-Clinical Model Of Relapse, Steven T. Pittenger Jun 2016

Examination Of Methamphetamine Reinstatement In Female And Male Rats: A Pre-Clinical Model Of Relapse, Steven T. Pittenger

Department of Psychology: Dissertations, Theses, and Student Research

Methamphetamine (meth) dependence is often characterized by persistent and chronic relapse (i.e., return to drug use). There is growing pre-clinical and human evidence suggesting females are at greater risk to relapse. The set of studies presented in this dissertation extended this limited evidence by identifying sex-dependent neural substrates correlated with meth-triggered reinstatement (Experiment 1) and by examining sex-differences in reinstatement triggered by drugs of abuse that are commonly co-abused with meth (Experiment 2). Female and male rats were trained to self-administer meth, received subsequent extinction sessions, and then tested for reinstatement. In Experiment 1, rats were perfused following reinstatement testing …


Suprachiasmatic Nucleus And Subparaventricular Zone Lesions Disrupt Circadian Rhythmicity But Not Light-Induced Masking Behavior In Nile Grass Rats, Andrew J. Gall, Dorela D. Shuboni, Lily Yan, Antonio A. Nunez, Laura Smale Apr 2016

Suprachiasmatic Nucleus And Subparaventricular Zone Lesions Disrupt Circadian Rhythmicity But Not Light-Induced Masking Behavior In Nile Grass Rats, Andrew J. Gall, Dorela D. Shuboni, Lily Yan, Antonio A. Nunez, Laura Smale

Faculty Publications

The ventral subparaventricular zone (vSPVZ) receives direct retinal input and influences the daily patterning of activity in rodents, making it a likely candidate for the mediation of acute behavioral responses to light (i.e., masking). We performed chemical lesions aimed at the vSPVZ of diurnal grass rats (Arvicanthis niloticus) using N-methyl-D,L-aspartic acid (NMA), a glutamate agonist. Following NMA lesions, we placed grass rats in various lighting conditions (e.g., 12:12 light-dark, constant dark, constant light); presented a series of light pulses at circadian times (CT) 6, 14, 18, and 22; and placed them in a 7-h ultradian cycle to assess behavioral masking. …


“My Logic Is Undeniable”: Replicating The Brain For Ideal Artificial Intelligence, Samuel C. Adams Apr 2016

“My Logic Is Undeniable”: Replicating The Brain For Ideal Artificial Intelligence, Samuel C. Adams

Senior Honors Theses

Alan Turing asked if machines can think, but intelligence is more than logic and reason. I ask if a machine can feel pain or joy, have visions and dreams, or paint a masterpiece. The human brain sets the bar high, and despite our progress, artificial intelligence has a long way to go. Studying neurology from a software engineer’s perspective reveals numerous uncanny similarities between the functionality of the brain and that of a computer. If the brain is a biological computer, then it is the embodiment of artificial intelligence beyond anything we have yet achieved, and its architecture is advanced …


Cognitive Phenotypes And The Evolution Of Animal Decisions, Tamra C. Mendelson, Courtney L. Fitzpatrick, Mark E. Hauber, Charles H. Pence, Rafael L. Rodríguez, Rebecca J. Safran, Caitlin A. Stern, Jeffrey R. Stevens Jan 2016

Cognitive Phenotypes And The Evolution Of Animal Decisions, Tamra C. Mendelson, Courtney L. Fitzpatrick, Mark E. Hauber, Charles H. Pence, Rafael L. Rodríguez, Rebecca J. Safran, Caitlin A. Stern, Jeffrey R. Stevens

Faculty Publications

Despite the clear fitness consequences of animal decisions, the science of animal decision making in evolutionary biology is underdeveloped compared with decision science in human psychology. Specifically, the field lacks a conceptual framework that defines and describes the relevant components of a decision, leading to imprecise language and concepts. The ‘judgment and decision-making’ (JDM) framework in human psychology is a powerful tool for framing and understanding human decisions, and we apply it here to components of animal decisions, which we refer to as ‘cognitive phenotypes’. We distinguish multiple cognitive phenotypes in the context of a JDM framework and highlight empirical …


The Domain Specificity Of Intertemporal Choice In Pinyon Jays, Jeffrey R. Stevens, Bryce Kennedy, Dina Morales, Marianna Burks Jan 2016

The Domain Specificity Of Intertemporal Choice In Pinyon Jays, Jeffrey R. Stevens, Bryce Kennedy, Dina Morales, Marianna Burks

Jeffrey Stevens Publications

When choosing between a piece of cake now versus a slimmer waistline in the future, many of us have difficulty with self-control. Food-caching species, however, regularly hide food for later recovery, sometimes waiting months before retrieving their caches. It remains unclear whether these long-term choices generalize outside of the caching domain. We hypothesized that the ability to save for the future is a general tendency that cuts across different situations. To test this hypothesis, we measured and experimentally manipulated caching to evaluate its relationship with operant measures of self-control in pinyon jays (Gymnorhinus cyanocephalus). We found no correlation …


Reflections Of The Social Environment In Chimpanzee Memory: Applying Rational Analysis Beyond Humans, Jeffrey R. Stevens, Julian N. Marewski, Lael J. Schooler, Ian C. Gilby Jan 2016

Reflections Of The Social Environment In Chimpanzee Memory: Applying Rational Analysis Beyond Humans, Jeffrey R. Stevens, Julian N. Marewski, Lael J. Schooler, Ian C. Gilby

Jeffrey Stevens Publications

In cognitive science, the rational analysis framework allows modelling of how physical and social environments impose information-processing demands onto cognitive systems. In humans, for example, past social contact among individuals predicts their future contact with linear and power functions. These features of the human environment constrain the optimal way to remember information and probably shape how memory records are retained and retrieved. We offer a primer on how biologists can apply rational analysis to study animal behaviour. Using chimpanzees (Pan troglodytes) as a case study, we modelled 19 years of observational data on their social contact patterns. Much …


Intertemporal Similarity: Discounting As A Last Resort, Jeffrey R. Stevens Jan 2016

Intertemporal Similarity: Discounting As A Last Resort, Jeffrey R. Stevens

Jeffrey Stevens Publications

Standard models of intertemporal choice assume that individuals discount future payoffs by integrating reward amounts and time delays to generate a discounted value. Alternative models propose that, rather than integrate across them, individuals compare within attributes (amounts and delays) to determine if differences in one attribute outweigh differences in another attribute. For instance, Leland (2002) and Rubinstein (2003) propose models that 1) compare the two reward amounts to determine whether they are similar, 2) compare the similarity of the two time delays, and then 3) make a decision based on these similarity judgments. Here, I tested discounting models against attribute-based …


Discriminative Stimulus Properties Of 1.25 Mg/Kg Clozapine In Rats: Mediation By Serotonin 5-Ht2 And Dopamine D4 Receptors, Adam J. Prus, Laura Wise, Alan L. Pehrson, Scott D. Philibin, Benny Bang-Andersen, Jørn Arnt, Joseph H. Porter Jan 2016

Discriminative Stimulus Properties Of 1.25 Mg/Kg Clozapine In Rats: Mediation By Serotonin 5-Ht2 And Dopamine D4 Receptors, Adam J. Prus, Laura Wise, Alan L. Pehrson, Scott D. Philibin, Benny Bang-Andersen, Jørn Arnt, Joseph H. Porter

Journal Articles

The atypical antipsychotic drug clozapine remains one of most effective treatments for schizophrenia, given a lack of extrapyramidal side effects, improvements in negative symptoms, cognitive impairment, and in symptoms in treatment-resistant schizophrenia. The adverse effects of clozapine, including agranulocytosis, make finding a safe clozapine-like a drug a goal for drug developers. The drug dis- crimination paradigm is a model of interoceptive stimulus that has been used in an effort to screen experimental drugs for clozapine-like atypical antipsychotic effects. The present study was conducted to elucidate the receptor-mediated stimulus properties that form this clozapine discriminative cue by testing selective receptor ligands …