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Biological Psychology Commons

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Full-Text Articles in Biological Psychology

Clinical Characteristics And Neuroanatomical Predictors Of Acute Antidepressant Outcome For Patients With Comorbid Depression And Mild Cognitive Impairment, Jeffrey N. Motter Sep 2019

Clinical Characteristics And Neuroanatomical Predictors Of Acute Antidepressant Outcome For Patients With Comorbid Depression And Mild Cognitive Impairment, Jeffrey N. Motter

Dissertations, Theses, and Capstone Projects

Background: Older adults presenting with both a depressive disorder (DEP) and cognitive impairment (CI) represent a unique, understudied population. The classification of cognitive impairment severity continues to be debated though it has recently been subtyped into late (LMCI) versus early (EMCI) stages. Previous studies have found associations between treatment outcome and both cortical thickness and white matter hyperintensities (WMH), though report inconsistent directionality and affected regions. In this study, we examined baseline clinical characteristics and neuroanatomical features as prognostic indicators for older adults with comorbid DEP and CI participating in an open antidepressant trial. EMCI is hypothesized to have greater …


Memory Complaint Profiles In Dementia Populations Utilizing The Memory Complaints Inventory, Becca N. Johnson May 2018

Memory Complaint Profiles In Dementia Populations Utilizing The Memory Complaints Inventory, Becca N. Johnson

MSU Graduate Theses

The Memory Complaints Inventory (MCI) is a self-report questionnaire developed by Paul Green to provide further effort-related evidence in neuropsychiatric practice. It is comprised of nine subscale scores, in addition to the imbedded Plausible and Implausible symptom validity scales. The current study utilized archival MCI scores in dementia populations to determine the presence of, and difference between, genuine memory impairment profiles in separate subgroups of cognitive impairment. The study sample consisted of 244 adults presenting to an outpatient neuropsychology practice for evaluation of memory impairment. The diagnostic categories of the sample consisted of Alzheimer’s Disease (n = 21), Vascular …