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Full-Text Articles in Biological Psychology
The Effects Of Lipopolysaccharide-Induced Neuroinflammation On Learning And Forgetting In Juvenile Rats, Michele Barry
The Effects Of Lipopolysaccharide-Induced Neuroinflammation On Learning And Forgetting In Juvenile Rats, Michele Barry
Seton Hall University Dissertations and Theses (ETDs)
The inability to remember events experienced very early in life is referred to as Infantile Amnesia (IA) and has been observed in both humans and animals. Over the years interest in the phenomenon waned, but has recently increased with the discovery of new neurobiological methods to study brain function (e.g., Callaghan, Li & Richardson, 2014). The neurobiological mechanism behind IA has yet to be determined, but several innovative theories have been developed with these new research methods. The neurogenesis hypothesis theorizes that increased neurogenesis during early development disrupts previously established memories. The hippocampus, an area that mediates both the memory …
The Short And Long-Term Effects Of Chronic Ketamine During Adolescence On Object Recognition Memory In Rats, William Hardin
The Short And Long-Term Effects Of Chronic Ketamine During Adolescence On Object Recognition Memory In Rats, William Hardin
Seton Hall University Dissertations and Theses (ETDs)
Prior research has demonstrated that ketamine causes deficits in object recognition and location memory following both acute and chronic administration (Pitsikas & Boultadakis, 2009; Venãncio et al., 2011). Although it is well established that abuse of many different kinds of drugs during the critical developmental period of adolescence can lead to impairments in cognition later in adulthood (Gilpin et al., 2012; Wagner et al., 2010), no research has investigated the effects of chronic ketamine administration during adolescence and its effects on behavior in adulthood. With recent research establishing that chronic ketamine during adolescence produces late-onset alterations in electrophysiology during adulthood …