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Articles 331 - 360 of 1557
Full-Text Articles in Psychology
The Relationship Between Acculturation And Depression With Burmese Refugees, Gunnar Greg Newman
The Relationship Between Acculturation And Depression With Burmese Refugees, Gunnar Greg Newman
Walden Dissertations and Doctoral Studies
Acculturation and acculturative stress have been linked to depression among immigrants and refugee populations. Asian Americans and Asian American subgroups are underrepresented and have been neglected in research. The purpose of this quantitative study was to measure the relationship between acculturation and depression with length of time in the United States and acculturative stress as mediating variables among the understudied Asian American subgroup, Burmese refugees resettled in the United States. Unidimensional and bidimensional models of acculturation form the theoretical framework for this study. Three instruments, the Suinn-Lew Asian Self Identity Acculturation scale, the Riverside Acculturation Stress Inventory, and the Beck …
Stressors And Depression Among Adolescents With Co-Rumination As A Moderator, Angela Grosso-Burke
Stressors And Depression Among Adolescents With Co-Rumination As A Moderator, Angela Grosso-Burke
Walden Dissertations and Doctoral Studies
Stress, depression, and co-rumination have been a focus of scholars in recent years. Although studies have considered the relationship among stressors, depression, and co-rumination, little is known about the moderating effects of co-rumination. This study aimed to address the gap in the literature by examining moderating effects of co-rumination on relations between stressors and depression, along with further moderating effects of sex, race, and grade. The current study examined mean-level race, sex, and grade differences in the relation among stressors (total, family, peer, physical appearance, sport/physical activity, school) and depressive symptoms in adolescents. Analyses were conducted to determine the relationship …
When The Bough Breaks: Alcohol Misuse Among Jamaican Young Adults, Marsha Smith
When The Bough Breaks: Alcohol Misuse Among Jamaican Young Adults, Marsha Smith
Antioch University Dissertations & Theses
The incidence of alcohol misuse globally continues to be a significant problem with copious adverse health and social causes and implications. The prevalence of alcohol misuse in Jamaica, British West Indies, instigated the trifold objective of this study. The ecological systems model provided a framework for conceptualizing multilayered biological and social processes that interact to determine mental health. This study examined anxiety and depression, family structure, and perceived parental warmth and control as predictors of alcohol misuse among young adults ages 18 to 30 residing in Jamaica. The current study revealed a correlation between alcohol misuse and higher levels of …
The Impact Of Social Connection And Psychological Resilience On Covid-19 Pandemic- Related Mental Health Outcomes, Shelby Lee Powers
The Impact Of Social Connection And Psychological Resilience On Covid-19 Pandemic- Related Mental Health Outcomes, Shelby Lee Powers
Doctor of Psychology (PsyD)
The COVID-19 pandemic has had wide reaching, well-documented impacts on mental health across demographics. Among these impacts are higher rates of depression and anxiety in adults. Several factors have been shown to mitigate the experience of depression and anxiety, including social connection and psychological resilience. The present study examined social connection and psychological resilience as predictors of depression and anxiety on a U.S. adult sample (n = 535) during the COVID-19 pandemic. Participants were recruited using Qualtrics. Results of this study described that over 30% of the variance in anxiety and depression was predicted by a person’s levels of social …
Examining Social Media Use, Connectedness, And Depression In Graduate Students, Marisa Gretz
Examining Social Media Use, Connectedness, And Depression In Graduate Students, Marisa Gretz
PCOM Psychology Dissertations
This study examined the relationship between social media use, sense of connectedness, and depression among graduate students. Graduate students are at risk of depression and often disconnect from their social supports due to their program's demands. Literature on the impact of social media on depression is discrepant. The relationship between a sense of connection, the use of social media, and depression in a graduate student population is a novel area of research. Graduate students at The Philadelphia College of Osteopathic Medicine (PCOM) and other universities, including healthcare and non-healthcare-related disciplines, were included. Participants were recruited via social media or email. …
Social Determinants Of Health And Functional Disability At Mid- And Late-Life, Carly Pullen
Social Determinants Of Health And Functional Disability At Mid- And Late-Life, Carly Pullen
Graduate Theses, Dissertations, and Problem Reports (ETD)
The number and proportion of older adults living in the U.S. and globally are increasing. Not only are more adults living longer (Rania et al., 2021), there is evidence that people are
entering late life with more functional disability than in previous generations (He & Larsen,
2014). Social determinants of health include demographic and environmental influences than can impact a range of health outcomes beyond more direct risk factors (Duran and Perez-Stable, 2019). Using data from 243,693 community-dwelling adults who completed the 2020 Behavioral Risk Factor Surveillance System survey, we tested the associations among social determinants of health (i.e., age, …
Association Between Trauma History And Body Image, Depression, Posttraumatic Stress, And Relationship Satisfaction In Postpartum Women, Kristen Hawk-Purcell
Association Between Trauma History And Body Image, Depression, Posttraumatic Stress, And Relationship Satisfaction In Postpartum Women, Kristen Hawk-Purcell
PCOM Psychology Dissertations
The postpartum period can be a time of significant change and transition. Little is known about how a history of trauma may impact functioning during this critical time. English-speaking adult women (age ≥ 18 years, N = 61) who gave birth in the United States in the past year, but not in the last month, were in an intimate relationship, and did not use any assisted reproductive technology to conceive participated in the study. Participants were recruited through social media and online forums related to pregnancy and the postpartum period. They completed a demographic questionnaire, the PTSD Checklist for Diagnostic …
The Impact Of Gender Minority Stress On Eating Pathology And Body Checking Behaviors In Transgender And Non-Binary Adults, Klaudia Bialy
The Impact Of Gender Minority Stress On Eating Pathology And Body Checking Behaviors In Transgender And Non-Binary Adults, Klaudia Bialy
PCOM Psychology Dissertations
Transgender and gender non-binary (TNB) individuals commonly report diminished mental health when compared to cisgender individuals. TNB individuals experience unique stressors due to their gender identity such as gender-based discrimination and victimization, internalized transphobia, and non-affirmation of their gender. Due to these unique stressors, TNB individuals experience elevated rates of psychological distress such as anxiety, depression, and suicidality. Additionally, TNB individuals report body image issues and disordered eating. This study examined if gender minority stress predicts the relationship between body checking behaviors and eating pathology amongst TNB individuals. Simple linear regression models were used to assess the possible impact gender …
Evaluation And Management Of Postpartum Depression In South Asian Women, Gujri Chadha
Evaluation And Management Of Postpartum Depression In South Asian Women, Gujri Chadha
Capstone Showcase
Postpartum depression is a worldwide phenomenon that affects about 10 to 20% of women within the first year of delivery. During the 12 months following delivery, about 85% of mothers experience a mood disturbance2. The importance of evaluating and managing postpartum depression is crucial as untreated postpartum depression can lead to a significant risk of morbidity for the child as well as the mother of the child3. Despite the remarkable prevalence of this diagnosis throughout cultures, the screening process for PPD is routinely missed, and the management is frequently incomplete for various reasons3. This phenomenon is exacerbated in minority populations …
The Lived Experience Of Lung Cancer Patients With Psychological Health And Physical Activity, Donna Leeann Homkes
The Lived Experience Of Lung Cancer Patients With Psychological Health And Physical Activity, Donna Leeann Homkes
Walden Dissertations and Doctoral Studies
AbstractPhysical activity (PA) is recognized as a treatment protocol for lung cancer patients that improves physical impairments and reduces symptoms of psychological stress. This qualitative interpretive phenomenological analysis (IPA) study was conducted to explore the lived experience of lung cancer patients and how PA is influenced by anxiety, depression, and fatigue. This study was guided by Bandura’s self-efficacy theory and Engel’s biopsychosocial model. In-depth semi structured interviews were conducted with seven lung cancer participants over Zoom and in person. The data were analyzed using manual hand coding. The analysis revealed themes in patients’ experiences about how PA participation is influenced …
The Predictive Effect Of Parent Closeness On Substance Use For Coping In Adoptees: An Application Of Motivational Models Of Substance Use, Alison B. Klein
The Predictive Effect Of Parent Closeness On Substance Use For Coping In Adoptees: An Application Of Motivational Models Of Substance Use, Alison B. Klein
Psychology Theses
To explain a previously observed triad of substance abuse, adoption, and poor mental health adjustment in adoptees, the proposed study applies the Substance Use Motivation Model. This model would suggest that adoptees are motivated to use substances to negatively reinforce (remove or mitigate) depression and anxiety symptomology. Parent closeness is an established protective factor against negative mental health symptomology and substance use, suggesting closeness may influence the relationship between negative mental health symptomology and motivations to use substances for coping. To test this relationship, 100 adoptees were administered the Substance Use Motives Measure (SUMM), the Personal Health Questionaire-9 (Depression), the …
Developing Resilience Online: Evaluation Of Synchronous And Asynchronous Resilience Interventions For Filipino College Students, Ma. Regina Hechanova, Rosanne M. Jocson, Arsenio S. Alianan, Junix Jerald I. Delos Santos, Jason O. Manaois, Gilda Gomez, Gina R. Lamzon
Developing Resilience Online: Evaluation Of Synchronous And Asynchronous Resilience Interventions For Filipino College Students, Ma. Regina Hechanova, Rosanne M. Jocson, Arsenio S. Alianan, Junix Jerald I. Delos Santos, Jason O. Manaois, Gilda Gomez, Gina R. Lamzon
Psychology Department Faculty Publications
This study evaluated two forms of a resilience intervention amongst college students during the COVID-19 pandemic. Utilising a randomised controlled trial design; it examined the impact of a synchronous and asynchronous resilience interventions versus a control group that did a journaling intervention. Outcomes measured included coping behaviour; non-reactivity; wellbeing; stress; depression and anxiety. Participants consisted of Filipino college students randomly assigned to three groups: synchronous online resilience group (n = 135); asynchronous resilience group (n = 121) and control group (n = 127). Results revealed that students who went through the online synchronous resilience reported a significant reduction in depression …
The Relationship Between Adolescent Stress In Five Domains And Depression: Rumination As A Moderator, Crystal Victoria Lupo
The Relationship Between Adolescent Stress In Five Domains And Depression: Rumination As A Moderator, Crystal Victoria Lupo
Walden Dissertations and Doctoral Studies
Prior to this study, understanding the impact of rumination as a moderating factor in predicting the interaction between specific domains of stress and adolescent depression remained largely unknown. Guided by the theoretical frameworks of response style theory of depression, control mastery theory, and diasthesis stress model, the purpose of this quantitative nonexperimental study was to examine the link between five domains of adolescent stress (i.e., school, family, peers, appearance, and sports) and depression, the relationship between rumination and depression, and the moderating effect of rumination on these relationships. Participants included previously data collected from 635 adolescents from a midwestern U.S.city. …
Consideration Of Mindfulness Intervention For Hispanic Adolescents In A School Setting, Kierra Mcshine Gregory
Consideration Of Mindfulness Intervention For Hispanic Adolescents In A School Setting, Kierra Mcshine Gregory
Walden Dissertations and Doctoral Studies
Hispanic adolescents’ accessibility to treatment options for depression is met with limitations associated with financial barriers and cultural misalignment. This research study aimed to bring to light an alternative psychotherapy treatment through the foundations of mindfulness interventions. The goal was to understand the experience of Hispanic adolescents when engaging in mindfulness in a school setting. The purpose of this study was to gather information about the experiences of Hispanic adolescents using mindfulness to support mental health practitioners, school counselors, and behavioral interventionists to provide treatment options that are accessible and meet the needs of this culture group. This explanatory case …
A Systematic Review And Meta-Analysis Of Long Term Physical And Mental Sequelae Of Covid-19 Pandemic: Call For Research Priority And Action, Na Zeng, Yi-Miao Zhao, Wei Yan, Chao Li, Qing-Dong Lu, Lin Liu, Shu-Yu Ni, Huan Mei, Kai Yuan, Le Shi, Peng Li, Teng-Teng Fan, Jun-Liang Yuan, Michael V Vitiello, Thomas Kosten, Alexandra L Kondratiuk, Hong-Qiang Sun, Xiang-Dong Tang, Mei-Yan Liu, Ajit Lalvani, Jie Shi, Yan-Ping Bao, Lin Lu
A Systematic Review And Meta-Analysis Of Long Term Physical And Mental Sequelae Of Covid-19 Pandemic: Call For Research Priority And Action, Na Zeng, Yi-Miao Zhao, Wei Yan, Chao Li, Qing-Dong Lu, Lin Liu, Shu-Yu Ni, Huan Mei, Kai Yuan, Le Shi, Peng Li, Teng-Teng Fan, Jun-Liang Yuan, Michael V Vitiello, Thomas Kosten, Alexandra L Kondratiuk, Hong-Qiang Sun, Xiang-Dong Tang, Mei-Yan Liu, Ajit Lalvani, Jie Shi, Yan-Ping Bao, Lin Lu
Faculty, Staff and Students Publications
The long-term physical and mental sequelae of COVID-19 are a growing public health concern, yet there is considerable uncertainty about their prevalence, persistence and predictors. We conducted a comprehensive, up-to-date meta-analysis of survivors' health consequences and sequelae for COVID-19. PubMed, Embase and the Cochrane Library were searched through Sep 30th, 2021. Observational studies that reported the prevalence of sequelae of COVID-19 were included. Two reviewers independently undertook the data extraction and quality assessment. Of the 36,625 records identified, a total of 151 studies were included involving 1,285,407 participants from thirty-two countries. At least one sequelae symptom occurred in 50.1% (95% …
Temporal Associations Between Posttraumatic Stress Symptoms And Depression In Response To Online Expressive Writing Interventions In A Hispanic Sample, Michiyo Hirai, Serkan Dolma, Laura L. Vernon, George A. Clum
Temporal Associations Between Posttraumatic Stress Symptoms And Depression In Response To Online Expressive Writing Interventions In A Hispanic Sample, Michiyo Hirai, Serkan Dolma, Laura L. Vernon, George A. Clum
Psychological Science Faculty Publications
Some expressive writing (EW) interventions targeting posttraumatic stress symptoms (PTSS) may reduce both PTSS and comorbid depression symptoms. The temporal associations between PTSS and depression symptom levels in response to EW interventions are unknown. This study examined the directionality of PTSS and depression symptom levels from baseline to 1-week, 1-month, and 3-month follow-ups of two online EW interventions in a Hispanic sample with diverse trauma experiences. Participants (n = 70) completed either emotion-focused or fact-focused writing for 3 consecutive days online. A manifest autoregressive model with cross-lagged effects and treatment condition was analyzed. All but one first-order autoregressive path …
At The Intersection Of Identity: An Exploration Of Sense Of Belonging And Depression, Kalah Brown
At The Intersection Of Identity: An Exploration Of Sense Of Belonging And Depression, Kalah Brown
CMC Senior Theses
Belonging is vital to our well-being, health, and identity. At the same time, belongingness is tied so closely to our identity, such that our specific identity may influence the extent to which we feel that we belong, as well as moderating the relationship between belonging and mental health. This present study investigates whether intersectionality, how and if a person is a minority, moderates the relationship between belonging and depression. College students were administered the Beck’s Depression Inventory II and the General Belongingness Scale. They also filled out demographic information to capture their identity and levels of intersectionality. Both belonging and …
Respiratory Sinus Arrhythmia And Depressive Symptoms: Considering The Role Of Cultural Orientation And Fit, Akriti Poudel
Respiratory Sinus Arrhythmia And Depressive Symptoms: Considering The Role Of Cultural Orientation And Fit, Akriti Poudel
CMC Senior Theses
The aim of this study was to examine the relationship between cultural orientation, respiratory sinus arrhythmia (RSA), and depression. Horizontal collectivism (HC) has been shown to be predictive of positive psychological adjustment (Oh, 2022; Schermer et al., 2023), but the extent to which the individual’s level of HC matches with the group is not well understood. RSA has traditionally been conceptualized as a measure of adaptive functioning; (Graziano & Derefinko, 2013; Qu & Leerkes, 2018, Hinnant et al., 2011) however, more recent research has proposed that RSA is better conceptualized as a marker of susceptibility to environmental influences (Sturge-Apple et …
The Relationship Between Body Mass Index And Depression In College Students, Bryn Kable
The Relationship Between Body Mass Index And Depression In College Students, Bryn Kable
CMC Senior Theses
College student mental health has seen a serious decline over the last decade (Esaki-Smith, 2022). One factor that has been linked to both physical and mental disorders is obesity. A common way to operationalize weight is through body mass index (BMI) (Ilman et al., 2015). There is evidence that BMI and depression are correlated linearly in that individuals with higher BMIs have higher levels of depression (Badillo et al., 2022; Simon et al., 2008). The exact mechanisms of this relationship are still generally unknown; thus, the goal of this study was to investigate the relationship between BMI and depression in …
The Lived Experience Of Lung Cancer Patients With Psychological Health And Physical Activity, Donna Leeann Homkes
The Lived Experience Of Lung Cancer Patients With Psychological Health And Physical Activity, Donna Leeann Homkes
Walden Dissertations and Doctoral Studies
AbstractPhysical activity (PA) is recognized as a treatment protocol for lung cancer patients that improves physical impairments and reduces symptoms of psychological stress. This qualitative interpretive phenomenological analysis (IPA) study was conducted to explore the lived experience of lung cancer patients and how PA is influenced by anxiety, depression, and fatigue. This study was guided by Bandura’s self-efficacy theory and Engel’s biopsychosocial model. In-depth semi structured interviews were conducted with seven lung cancer participants over Zoom and in person. The data were analyzed using manual hand coding. The analysis revealed themes in patients’ experiences about how PA participation is influenced …
You've Got A Friend: Social Factors And Depressive Symptoms In Older Adults, Erika A. Fenstermacher
You've Got A Friend: Social Factors And Depressive Symptoms In Older Adults, Erika A. Fenstermacher
Graduate Theses, Dissertations, and Problem Reports (ETD)
Depression in late life has been associated with disability, lower quality of life, increased mortality, and increased risk of suicide (Fiske et al., 2009; Rodda et al., 2011). Research suggests that functional disability, which is often brought about by a medical condition, may precede depressive symptoms and may be a major factor for older adults developing depression (Ormel et al., 2002). Social support can be beneficial for both emotional and physical health (Fiori & Jager, 2021). Numerous studies found evidence that social networks, perceived and subjective social support, and satisfaction with support received moderated the relation between health problems and …
Consideration Of Mindfulness Intervention For Hispanic Adolescents In A School Setting, Kierra Mcshine Gregory
Consideration Of Mindfulness Intervention For Hispanic Adolescents In A School Setting, Kierra Mcshine Gregory
Walden Dissertations and Doctoral Studies
Hispanic adolescents’ accessibility to treatment options for depression is met with limitations associated with financial barriers and cultural misalignment. This research study aimed to bring to light an alternative psychotherapy treatment through the foundations of mindfulness interventions. The goal was to understand the experience of Hispanic adolescents when engaging in mindfulness in a school setting. The purpose of this study was to gather information about the experiences of Hispanic adolescents using mindfulness to support mental health practitioners, school counselors, and behavioral interventionists to provide treatment options that are accessible and meet the needs of this culture group. This explanatory case …
The Relationship Between Adolescent Stress In Five Domains And Depression: Rumination As A Moderator, Crystal Victoria Lupo
The Relationship Between Adolescent Stress In Five Domains And Depression: Rumination As A Moderator, Crystal Victoria Lupo
Walden Dissertations and Doctoral Studies
Prior to this study, understanding the impact of rumination as a moderating factor in predicting the interaction between specific domains of stress and adolescent depression remained largely unknown. Guided by the theoretical frameworks of response style theory of depression, control mastery theory, and diasthesis stress model, the purpose of this quantitative nonexperimental study was to examine the link between five domains of adolescent stress (i.e., school, family, peers, appearance, and sports) and depression, the relationship between rumination and depression, and the moderating effect of rumination on these relationships. Participants included previously data collected from 635 adolescents from a midwestern U.S.city. …
Parent And Adolescent Report Of Helicopter Parenting: Examining Reporter Discrepancies And Associations With Adolescent Depression And Anxiety, Avneet Batra
Graduate Theses, Dissertations, and Problem Reports (ETD)
Research is replete with studies on Helicopter Parenting (HP) and its association with depression and anxiety (Cui et al., 2019; Schiffrin et al., 2014; 2019). However, most of the studies have focused on college students’ reports on helicopter parenting and there is relative dearth of studies with adolescents or with parents’ reports of HP (Pistella et al., 2020; Schiffrin et al., 2019). The current study aims to fill the gap in the literature by including both parent and adolescents’ perspectives on helicopter parenting, assess its unique association (parent and teens HP reports) with teen depression and anxiety both concurrently and …
Childhood Bullying Victimization, Emotion Regulation, Rumination, Distress Tolerance, And Depressive Symptoms: A Cross-National Examination Among Young Adults In Seven Countries, Madelyn H. Labella, Neelamberi D. Klein, Georgina Yeboah, Claire Bailey, Ashley N. Doane, Debra Kaminer, Adrian J. Bravo, Cross-Cultural Addictions Study Team
Childhood Bullying Victimization, Emotion Regulation, Rumination, Distress Tolerance, And Depressive Symptoms: A Cross-National Examination Among Young Adults In Seven Countries, Madelyn H. Labella, Neelamberi D. Klein, Georgina Yeboah, Claire Bailey, Ashley N. Doane, Debra Kaminer, Adrian J. Bravo, Cross-Cultural Addictions Study Team
Psychology Faculty Publications
Existing research suggests a robust association between childhood bullying victimization and depressive symptoms in adulthood, but less is known about potential mediators of this link. Furthermore, there is limited cross-national research evaluating similarities and differences in bullying victimization and its associations with mental health. The current study addressed gaps in the literature by evaluating cognitive and affective responses to stress (i.e., emotion regulation, rumination, and distress tolerance) as potential mediators of the link between recalled bullying victimization and current depressive symptoms among 5909 (70.6% female) college students from seven countries. Results revealed specific indirect associations of bullying victimization through distress …
Depression And Insomnia Among Healthcare Professionals During Covid-19 Pandemic In Ethiopia: A Systematic Review And Meta-Analysis, Aragaw Asfaw Hasen, Abubeker Alebachew Seid, Ahmed Adem Mohammed
Depression And Insomnia Among Healthcare Professionals During Covid-19 Pandemic In Ethiopia: A Systematic Review And Meta-Analysis, Aragaw Asfaw Hasen, Abubeker Alebachew Seid, Ahmed Adem Mohammed
Faculty, Staff and Student Publications
INTRODUCTION: Healthcare professionals play a great role in the struggle against COVID-19. They are highly susceptible to COVID-19 due to their responsibilities. This susceptibility directly affects their mental health status. Comprehensive evidence on prevalence of depression and insomnia during this pandemic is vital. Thus, this study aims to provide the pooled prevalence of depression and insomnia, and their associated factors during the COVID-19 pandemic.
MATERIALS AND METHODS: This systematic review and meta-analysis follow the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) guidelines. Studies were searched from PubMed, Cochrane Library, CrossRef, African Journals Online and Google Scholar databases from …
Non-Canonical Pathways In The Pathophysiology And Therapeutics Of Bipolar Disorder, Rodrigo Machado-Vieira, Alan C Courtes, Carlos A Zarate, Ioline D Henter, Husseini K Manji
Non-Canonical Pathways In The Pathophysiology And Therapeutics Of Bipolar Disorder, Rodrigo Machado-Vieira, Alan C Courtes, Carlos A Zarate, Ioline D Henter, Husseini K Manji
Faculty, Staff and Student Publications
Bipolar disorder (BD) is characterized by extreme mood swings ranging from manic/hypomanic to depressive episodes. The severity, duration, and frequency of these episodes can vary widely between individuals, significantly impacting quality of life. Individuals with BD spend almost half their lives experiencing mood symptoms, especially depression, as well as associated clinical dimensions such as anhedonia, fatigue, suicidality, anxiety, and neurovegetative symptoms. Persistent mood symptoms have been associated with premature mortality, accelerated aging, and elevated prevalence of treatment-resistant depression. Recent efforts have expanded our understanding of the neurobiology of BD and the downstream targets that may help track clinical outcomes and …
Flying Blind: Exploring The Visual Cues Used By Helicopter Pilots In Degraded Visual Environments, Brandon Dreslin, Molly C. Mersinger, Shivani Patel, Alex Chaparro
Flying Blind: Exploring The Visual Cues Used By Helicopter Pilots In Degraded Visual Environments, Brandon Dreslin, Molly C. Mersinger, Shivani Patel, Alex Chaparro
Publications
Helicopter pilots rely on visual cues from the environment and instrument displays during critical phases of flight – particularly final approach and landing – to safely land. However, the specific visual cues pilots rely on and how they integrate those cues to make anticipatory inceptor inputs or corrections are not well understood. Importantly, those cues may be degraded under nighttime and brownout/whiteout conditions where the downwash of a helicopter’s rotors cause loose dirt/snow to be projected into the air, resulting in the obfuscation of the pilot’s vision outside the aircraft. The lack of visual cues in these conditions means that …
Tiam1-Mediated Synaptic Plasticity Underlies Comorbid Depression-Like And Ketamine Antidepressant-Like Actions In Chronic Pain, Qin Ru, Yungang Lu, Ali Bin Saifullah, Francisco A Blanco, Changqun Yao, Juan P Cata, De-Pei Li, Kimberley F Tolias, Lingyong Li
Tiam1-Mediated Synaptic Plasticity Underlies Comorbid Depression-Like And Ketamine Antidepressant-Like Actions In Chronic Pain, Qin Ru, Yungang Lu, Ali Bin Saifullah, Francisco A Blanco, Changqun Yao, Juan P Cata, De-Pei Li, Kimberley F Tolias, Lingyong Li
Faculty, Staff and Students Publications
Chronic pain often leads to depression, increasing patient suffering and worsening prognosis. While hyperactivity of the anterior cingulate cortex (ACC) appears to be critically involved, the molecular mechanisms underlying comorbid depressive symptoms in chronic pain remain elusive. T cell lymphoma invasion and metastasis 1 (Tiam1) is a Rac1 guanine nucleotide exchange factor (GEF) that promotes dendrite, spine, and synapse development during brain development. Here, we show that Tiam1 orchestrates synaptic structural and functional plasticity in ACC neurons via actin cytoskeleton reorganization and synaptic N-methyl-d-aspartate receptor (NMDAR) stabilization. This Tiam1-coordinated synaptic plasticity underpins ACC hyperactivity and drives chronic pain-induced depressive-like behaviors. …
A Novel Test Of Emotion Recognition Bias Using Dynamic Facial Morphing, Michael R. Gallagher
A Novel Test Of Emotion Recognition Bias Using Dynamic Facial Morphing, Michael R. Gallagher
Theses and Dissertations
Depressed persons have demonstrated emotion based cognitive biases, specifically surrounding vigilance of negative information and avoidance of positivity. These biases are sometimes operationalized through emotion recognition tasks. However, previous emotion recognition tasks lack in their ability to accurately measure and decompose positivity avoidance with enhanced negativity, while accounting for basic cognitive processes that can drive the results. Therefore, we developed a novel emotion recognition task that examines emotional intensity thresholds, while accounting for general response bias. Linear mixed effects modeling revealed substantial individual differences on all conditions in the task, using both frequentist and Bayesian approaches. Additionally, the findings suggest …