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Articles 361 - 390 of 3984
Full-Text Articles in Psychology
Pseudo-Science And ‘Fake’ News ‘Inventing’ Epidemics And The Police State, Babette Babich
Pseudo-Science And ‘Fake’ News ‘Inventing’ Epidemics And The Police State, Babette Babich
Articles and Chapters in Academic Book Collections
No abstract provided.
Family Functioning As A Moderator In The Relation Between Perceived Stress And Psychotic-Like Experiences Among Adolescents During Covid-19, Zhipeng Wu, Zhulin Zou, Feiwen Wang, Zhibiao Xiang, Mengran Zhu, Yicheng Long, Haojuan Tao, Lena Palaniyappan, Zhening Liu
Family Functioning As A Moderator In The Relation Between Perceived Stress And Psychotic-Like Experiences Among Adolescents During Covid-19, Zhipeng Wu, Zhulin Zou, Feiwen Wang, Zhibiao Xiang, Mengran Zhu, Yicheng Long, Haojuan Tao, Lena Palaniyappan, Zhening Liu
Brain and Mind Institute Researchers' Publications
Background: The COVID-19 pandemic has increased psychological stress among adolescents, and the relation between perceived stress (PS) and psychotic-like experiences (PLEs) has been well-established. However, little is known about the role of family functioning (FF) in this relation, especially when adolescents experienced the extended lockdown period with family members. Methods: A total of 4807 adolescents completed this retrospective paper-and-pencil survey after school reopening between May 14th and June 6th, 2020 in Hunan Province, China. We measured PS with the Perceived stress scale (PSS-10), PLEs with the eight positive items from Community Assessment of Psychic Experiences (CAPE-8), and FF with the …
Migrant Misconceptions: A Review Of Literature On National Heritage, Immigration Status, And Juvenile Offending, Serita Whiting
Migrant Misconceptions: A Review Of Literature On National Heritage, Immigration Status, And Juvenile Offending, Serita Whiting
Contemporary Issues in Juvenile Justice
In 2020, the Pew Research Center reported over 40 million Latinx adults are immigrants and nearly 23% are U.S.-born adult children of immigrant parents. Some rhetoric that surrounds immigration is indicative of crime, criminals, and the need to build a wall to protect the U.S. border from migrant crossing. In the U.S., immigration policies apply a 'securitized' approach to criminal law enforcement involving Latinos. However, criminological literature indicates immigrants do not pose any more of a threat towards crime than a natural-born citizen. Continued research should be completed to better understand differences among immigrant youth compared to native-born Latino youth.
The Overrepresentation Of Youth With Disabilities In The Juvenile Justice System, Keidra Mcgriff
The Overrepresentation Of Youth With Disabilities In The Juvenile Justice System, Keidra Mcgriff
Contemporary Issues in Juvenile Justice
This paper discusses the contributing factors and effects of youth[VD(1] with disabilities in the juvenile justice system. The disabilities discussed will be those of social, emotional, learning, and behavioral; presenting disconnections between these children, youth, educational system, and juvenile justice system. [VD(2] The juvenile justice system encompasses youth with behavior attributed to their disability that has been criminalized and thereby labeled as a delinquent. A juvenile delinquent is defined as "a minor who…commits anti-social or criminal acts, like vandalism or violence" (Dictionary.com, 2016). Such behavior could be disorderly conduct or temper tantrums that is criminalized as assault or general …
Severe Emotional And Behavioral Problems: Barriers For Texas Youth Accessing Mental Health Court Programs, Justin Joseph
Severe Emotional And Behavioral Problems: Barriers For Texas Youth Accessing Mental Health Court Programs, Justin Joseph
Contemporary Issues in Juvenile Justice
Conduct disorder is a constellation of continuous emotional and behavioral problems observed in children and adolescents, which may involve violent and non-violent antisocial behaviors. The symptomology of this psychological disorder includes: disregarding rules without clear reason, cruel or aggressive behavior toward people or animals (e.g., bullying, fighting, using dangerous weapons, forcing sexual activity, and stealing), skipping school, excessive substance use, pathological lying, manipulation, running away, and vandalism (American Psychiatric Association (APA), 2013). Texas Juvenile Mental Health Courts are designed to reduce the number of detained youth, divert at-risk children, maintain community safety, and utilize multidisciplinary approaches to treat conduct disordered …
Miami-Dade County Status Offenders: A Literature Review Of Punishment And Rehabilitation Of Youth, Colette B. Harris
Miami-Dade County Status Offenders: A Literature Review Of Punishment And Rehabilitation Of Youth, Colette B. Harris
Contemporary Issues in Juvenile Justice
The number of juveniles in detention centers has decreased across the United States. Although overall incarceration rates of juveniles in Miami-Dade County have declined, the number of youths at risk for delinquent activity and the number of girls in detention centers has increased. In the last nine years, Florida legislators have created laws to eliminate zero-tolerance policies in county schools, lessened the punishment role of law enforcement officers for in-school behaviors, as well as minimized the presence of law enforcement officers on school grounds. Although Miami-Dade County has been a part of the reformation of the Florida juvenile justice system, …
Right Against Self-Incrimination: Revealing The Mental Health History Of Justice-Involved Youth, Sesha Kethineni, Colette B. Harris
Right Against Self-Incrimination: Revealing The Mental Health History Of Justice-Involved Youth, Sesha Kethineni, Colette B. Harris
Contemporary Issues in Juvenile Justice
In the last two decades, the juvenile justice system has focused on the early identification of youth mental health to provide timely assessment and needed treatment. However, there are potential risks in divulging youth mental health status because the information is often made available to juvenile courts and probation departments. Many state statutes allow such information to be used in the admission of guilt, adjudication, and dispositional phases. The study reviewed state and federal statutes related to protections against self-incrimination of youth at eight different stages of the juvenile justice system. A systematic content analysis of secondary sources and legislative …
Ethnic Variations In Levels Of Conventional Bonding Among Different Black Adolescents In The United States: Implications For Behavioral Resilience, Shantol Mcintosh, Sherri Simmons-Horton, Frank Barnes
Ethnic Variations In Levels Of Conventional Bonding Among Different Black Adolescents In The United States: Implications For Behavioral Resilience, Shantol Mcintosh, Sherri Simmons-Horton, Frank Barnes
Contemporary Issues in Juvenile Justice
The quantitative study offers a description of how Caribbean-descended and African American adolescents in a national sample compare on strands of Hirschi’s conventional bond in terms of deviance and justice system involvement. Using a sample of 1,141 adolescents from the National Survey of American Life-Adolescent data, these groups were compared with tests of significance. The results indicate that belief and attachment are the most significant predictors of justice system contact. While Caribbean youth reported more deviance, this was not predictive of more justice system involvement than African Americans. Explanations for these findings and practice implications are offered.
The Development Of The Adaptable Self-Disclosure Scale (Asds): A Multidimensional Approach To Disclosure Assessment, Brandon Mcintyre
The Development Of The Adaptable Self-Disclosure Scale (Asds): A Multidimensional Approach To Disclosure Assessment, Brandon Mcintyre
All Dissertations
Understanding how individuals share or conceal parts of their identity has long been a topic of research with little consistency of measurement validation. The present study had three main goals: (1) define and conceptualize a multidimensional model of identity disclosure that can apply to any concealable identity, (2) generate a validated and adaptable scale for assessing any concealable identity, and (3) demonstrate the adaptability of this scale for a specific concealable identity. In Study 1, the proposed disclosure model was used to generate 72 items which were narrowed down using factor analysis to form the Adaptable Self-Disclosure Scale (ASDS). The …
What Long-Term Effects Occur From Combat Deployment In Effecting Later Adaptation To Civilian Life?, Corey E. Waites
What Long-Term Effects Occur From Combat Deployment In Effecting Later Adaptation To Civilian Life?, Corey E. Waites
Doctoral Dissertations and Projects
This study shows the effects that combat exposure can have on an individual by compiling information gained from surveys and collecting data from Facebook interactions. Members of the study who were deployed to the Southern area of Baghdad, Iraq, between 2003-2005 were included in this research after they voluntarily responded to an initial group message on Facebook to members of the 703rd medical company members. This research sets out to determine how a review of the veterans of the US Army 3rd Infantry Division 703rd medical unit between the years 2003-2005 in Iraq can tell us about the long-term effects …
Secondary Traumatic Stress In School Psychology Practicum And Internship Students, John Phillip Burnett
Secondary Traumatic Stress In School Psychology Practicum And Internship Students, John Phillip Burnett
Electronic Theses and Dissertations
School psychology practicum and internship students increasingly engaged in activities in which they assisted children and clients who were survivors of various traumatic experiences. It has become apparent that the psychological effects of secondary traumatic stress (STS) extend beyond those directly affected and impact those in a variety of helping professions. Despite research that examined STS in various helping professions, gaps currently exist that describe STS in school psychology. In reported research, similar helping professionals engaged in school psychology service activities, which resulted in elevated STS symptoms and other adverse outcomes (Ravi et al., 2021). This study posited that school …
The Giver: Vision & Memory, Alexander J. Dontre
The Giver: Vision & Memory, Alexander J. Dontre
All Faculty and Staff Scholarship
A memory hole is the banishment of problematic thoughts. We exile that which we prefer not to exist. Enter the perilous Memory Hole: The Psychology of Dystopia, to explore a legion of social and psychological themes through the lens of dystopian literature. The crushing fist of 1984 annihilating thoughts from existence as a means of persuasion. The exquisite seduction of addiction as an agent of control in Brave New World. Incineration of the written word to bask in the embers of peace of mind in Fahrenheit 451. Each chapter weaves in and out of the dystopian realms forged …
Intellectual Risk Taking: A Moderating Link Between Creative Confidence And Creative Behavior?, Ronald A. Beghetto, Maciej Karwowski, Roni Reiter-Palmon
Intellectual Risk Taking: A Moderating Link Between Creative Confidence And Creative Behavior?, Ronald A. Beghetto, Maciej Karwowski, Roni Reiter-Palmon
Psychology Faculty Publications
Having confidence in one’s creative ability seems necessary for creative behavior. The relationship, however, may not be as direct as creativity researchers have initially posited. Previous research on the relationship between creative confidence (CC) and creative behavior (CB) has yielded mixed findings. Moreover, emerging theoretical and empirical work suggests that the CC–CB relationship is moderated by other beliefs. In this exploratory study, we examined the relationship among intellectual risk taking (IRT), CC, and CB. Specifically, we tested 2 theoretical propositions. The first involved examining the posited relationship between creative confidence and creative behaviors. Consistent with our expectations, our preliminary results …
Irene Kraegel On Christian Mindfulness, Irene Kraegel
Irene Kraegel On Christian Mindfulness, Irene Kraegel
University Faculty Publications and Creative Works
Irene Kraegel is a pioneer in exploring mindfulness from a Christian perspective. Dave Schmelzer explored some of her insights in the previous The Pocket Contemplative. She joins us in this episode to walk us through how she's arrived at her unique life mission and to offer wise counsel to those of us on a similar journey
Cognitive Effects Of Alcohol Use And Sleep Disruption In College Students, Taylor English
Cognitive Effects Of Alcohol Use And Sleep Disruption In College Students, Taylor English
Department of Psychology: Dissertations, Theses, and Student Research
Alcohol use and sleep disruption are highly prevalent amongst college students, yet their combined effects on cognitive functioning and subsequent classroom performance have not been fully examined. Alcohol use has been shown to negatively impact cognitive functioning, especially in college students without fully matured brain regions. This has led to decreases in academic functioning and increases in college dropout. Disruptions in sleep functioning can lead to both lapses in attention and an overall decrease in attention, which can negatively impact learning in a classroom environment.
Participants were 96 undergraduate students who were invited to participate based on responses from a …
Measuring The Effects Of Social Isolation And Dissatisfaction On Depressive Symptoms During The Covid-19 Pandemic: The Moderating Role Of Sleep And Physical Activity, Ivan Vargas, Erin Kaye Howie, Alexandria Muench, Michael L. Perlis
Measuring The Effects Of Social Isolation And Dissatisfaction On Depressive Symptoms During The Covid-19 Pandemic: The Moderating Role Of Sleep And Physical Activity, Ivan Vargas, Erin Kaye Howie, Alexandria Muench, Michael L. Perlis
Psychological Science Faculty Publications and Presentations
Social distancing was universally implemented to reduce the spread of the COVID-19 virus. Long-term social distancing can lead to increased feelings of social isolation or dissatisfaction with one's daily interpersonal interactions, which can subsequently result in reduced psychological health (e.g., greater depression). The present study quantified this association, and the extent to which it was moderated by measures of sleep and physical activity, by surveying 3658 adults (mean age = 46.0 years) from across the United States. Participants answered questions related to their social experiences, sleep, physical activity, and depressive symptoms during the early stages of the pandemic (March-June 2020). …
Designing A Multiple Submission Policy Supporting Mastery Learning For A Design Thinking Class In A Purely Online Learning Environment, Marianne Kayle Amurao, Joseph Benjamin R. Ilagan
Designing A Multiple Submission Policy Supporting Mastery Learning For A Design Thinking Class In A Purely Online Learning Environment, Marianne Kayle Amurao, Joseph Benjamin R. Ilagan
Quantitative Methods and Information Technology Faculty Publications
Mastery learning is defined as an approach where students are equipped with complex skills required in the VUCA world instead of simple skills that only apply to traditional classrooms. One way to encourage mastery learning in the classroom is through repeated assessment, specifically formative ones. In this paper, we describe our experience in designing a multiple submission policy to support mastery learning for a design thinking class taught purely online amidst lockdowns due to COVID. The transition to online learning and today’s context presented an opportunity to target mastery learning instead of traditional learning outcomes, which we achieved in two …
Latinx Caregivers’ Perceived Need For And Utilization Of Youth Telepsychology Services During The Coronavirus Pandemic, Alejandro L. Vázquez, Cynthia M. Navarro Flores, María De La Caridad Alvarez, Melanie M. Domenech Rodríguez
Latinx Caregivers’ Perceived Need For And Utilization Of Youth Telepsychology Services During The Coronavirus Pandemic, Alejandro L. Vázquez, Cynthia M. Navarro Flores, María De La Caridad Alvarez, Melanie M. Domenech Rodríguez
Psychology Faculty Publications
Telepsychology has the potential to provide a safe method of addressing mental health problems among Latinx youth during the coronavirus pandemic. However, the extent to which Latinx caregivers are accessing telepsychology services for their child and whether this format is perceived to be an appropriate method of addressing youth psychopathology is unknown. The present study examined indicators of youth psychopathology and external stressors in relation to Latinx caregivers’ perceived need for and utilization of youth telepsychology during the coronavirus pandemic. The sample consisted of 598 Latinx caregivers of school-age youths (MAge = 11.9, SD = 3.4) from across the United …
Reinforcer Preferences Of Liberty University Professors, Sarah Stoker
Reinforcer Preferences Of Liberty University Professors, Sarah Stoker
Senior Honors Theses
Prior research in Organizational Behavior Management (OBM) has found positive reinforcement effective for increasing work performance when rewards are reinforcing to the individual. Research also supports the efficacy of stimulus preference assessments (SPAs) in identifying reinforcers. The purpose of this study was to identify reinforcers for faculty at Liberty University. The hypotheses were, in a sample of faculty in Liberty University’s School of Behavioral Sciences (1) potential reinforcers other than monetary reinforcers will be identified as high-preference items and (2) tangible items will be identified as low-preference items. Hypotheses were tested using an online survey with Likert scales and written …
Language Analysis In Solution-Focused Therapy Training: Comparing Trainees With Their Trainer, Alberto Zamanillo, Alberto Rodríguez-Morejón
Language Analysis In Solution-Focused Therapy Training: Comparing Trainees With Their Trainer, Alberto Zamanillo, Alberto Rodríguez-Morejón
Journal of Solution Focused Practices
No abstract provided.
Organizational Change Process Milwaukee - Site Overview, Quality Improvement Center For Workforce Development
Organizational Change Process Milwaukee - Site Overview, Quality Improvement Center For Workforce Development
Other QIC-WD Products
The Division of Milwaukee Child Protective Services (DMCPS) of the Wisconsin Department of Children and Families (DCF) has approximately 185 State employees, responsible for the delivery of child protective services and ongoing case management services through contract agencies in Milwaukee County. DMCPS performs intake and investigative functions, while ongoing casework is managed by partner agencies in the community.
The majority of DMCPS staff work in the Access Section (hotline) and the Initial Assessment Bureau (IAB). Within the IAB was a constellation of Initial Assessment Specialists (IAS), mentors, supervisors, and program directors, who are led by the Bureau Director. While the …
#Eegmanylabs: Investigating The Replicability Of Influential Eeg Experiments, Yuri G. Pavlov, Nika Adamian, Stefan Appelhoff, Mahnaz Arvaneh, Sarah Sass, 47 Additional Authors
#Eegmanylabs: Investigating The Replicability Of Influential Eeg Experiments, Yuri G. Pavlov, Nika Adamian, Stefan Appelhoff, Mahnaz Arvaneh, Sarah Sass, 47 Additional Authors
Psychology Faculty Publications and Presentations
There is growing awareness across the neuroscience community that the replicability of findings about the relationship between brain activity and cognitive phenomena can be improved by conducting studies with high statistical power that adhere to well-defined and standardised analysis pipelines. Inspired by recent efforts from the psychological sciences, and with the desire to examine some of the foundational findings using electroencephalography (EEG), we have launched #EEGManyLabs, a large-scale international collaborative replication effort. Since its discovery in the early 20th century, EEG has had a profound influence on our understanding of human cognition, but there is limited evidence on the replicability …
Identifying App-Based Meditation Habits And The Associated Mental Health Benefits: Longitudinal Observational Study, Chad Stecher, Vincent Berardi, Ryan Fowers, Jaclyn Christ, Yunro Chung, Jennifer Huberty
Identifying App-Based Meditation Habits And The Associated Mental Health Benefits: Longitudinal Observational Study, Chad Stecher, Vincent Berardi, Ryan Fowers, Jaclyn Christ, Yunro Chung, Jennifer Huberty
Psychology Faculty Articles and Research
Background: Behavioral habits are often initiated by contextual cues that occur at approximately the same time each day; so, it may be possible to identify a reflexive habit based on the temporal similarity of repeated daily behavior. Mobile health tools provide the detailed, longitudinal data necessary for constructing such an indicator of reflexive habits, which can improve our understanding of habit formation and help design more effective mobile health interventions for promoting healthier habits.
Objective: This study aims to use behavioral data from a commercial mindfulness meditation mobile phone app to construct an indicator of reflexive meditation habits …
An Exploration Of The Psychological Impact Of Hacking Victimization, Alexa Palassis, Craig P. Speelman, Julie Ann Pooley
An Exploration Of The Psychological Impact Of Hacking Victimization, Alexa Palassis, Craig P. Speelman, Julie Ann Pooley
Research outputs 2014 to 2021
Cybercrime has rapidly grown in prevalence and potential for harm and disruption for victims. Studies have examined the adverse psychological impact of cybercrime for victims; however, the specific effects for victims of hacking are unexplored. The present study aimed to investigate the psychological impacts of hacking victimization through exploration of the experience of victims of hacking. The study employed an in-depth phenomenological approach to explore the experiences of 11 victims of hacking. Semi-structured interviews were used as a tool for data collection, and thematic analysis of the data revealed four main themes: emotional impact; an increased sense of vulnerability; a …
Nudging Students To Use Stronger Passwords: A Test Of Big Five Personality-Based Messages, Shelia Kennison, Eric Chan-Tin
Nudging Students To Use Stronger Passwords: A Test Of Big Five Personality-Based Messages, Shelia Kennison, Eric Chan-Tin
Computer Science: Faculty Publications and Other Works
Cybersecurity breaches can occur when one uses an easily hacked password. Prior research has investigated 1) possible steps to encourage users to use strong passwords and 2) how personality is related to users using strong passwords.
We investigated whether personality-based nudging messages based on Big Five traits could nudge people to create stronger passwords (c.f., Jones et al., 2021). We also examined how personal characteristics, such as gender, age, personality traits, password knowledge, attitudes, and behavior, and need for cognition, were related to password strength.
We tested the hypothesis that passwords created following messages matching participants’ personality would be stronger …
Tweets R Us: Predicting Personality From Language And Emoji Use On Twitter, Maxwell Meckling, Sarah Shoup, D. E. Chan-Tin, Shelia Kennison
Tweets R Us: Predicting Personality From Language And Emoji Use On Twitter, Maxwell Meckling, Sarah Shoup, D. E. Chan-Tin, Shelia Kennison
Computer Science: Faculty Publications and Other Works
The research investigated the suggestion from prior research that language and emojis use on Twitter and other social media platforms can predict users’ personality and gender (Adali et al., 2014; Golbeck et al., 2011; Li et al., 2019; Moreno et al., 2019; Raess, 2018). Some studies have also analyzed Twitter language to identify individuals with specific health conditions (e.g., alcohol recovery, Golbeck, 2012; sleep problems, Suarez et al., 2018).
If strategies to predict Twitter users’ characteristics prove to be successful, future efforts to direct persuasive messages related to recommended practices in public health and/or cybersecurity will be possible. Commercial applications …
Mitophagy In Depression: Pathophysiology And Treatment Targets, Ashutosh Tripathi, Giselli Scaini, Tatiana Barichello, João Quevedo, Anilkumar Pillai
Mitophagy In Depression: Pathophysiology And Treatment Targets, Ashutosh Tripathi, Giselli Scaini, Tatiana Barichello, João Quevedo, Anilkumar Pillai
Faculty, Staff and Student Publications
Mitochondria, the 'powerhouse' of eukaryotic cells, play a key role in cellular homeostasis. However, defective mitochondria increase mitochondrial ROS (mtROS) production and cell-free mitochondrial DNA (mtDNA) release, leading to increased inflammation. Mitophagy is a vital pathway, which selectively removes defective mitochondria through the process of autophagy. Thus, an impairment in the mitophagy pathway might trigger the gradual accumulation of defective mitochondria. Accumulating evidence suggest that inflammation and mitochondrial dysfunction are linked to the pathogenesis of depression. In this article, we have reviewed the role of impaired mitophagy as a contributing factor in depression pathophysiology. Further, we have discussed the potential …
Analysis Of Covid-19 Infection And Mortality Among Patients With Psychiatric Disorders, 2020, Antonio L Teixeira, Trudy Millard Krause, Lopita Ghosh, Lokesh Shahani, Rodrigo Machado-Vieira, Scott D Lane, Eric Boerwinkle, Jair C Soares
Analysis Of Covid-19 Infection And Mortality Among Patients With Psychiatric Disorders, 2020, Antonio L Teixeira, Trudy Millard Krause, Lopita Ghosh, Lokesh Shahani, Rodrigo Machado-Vieira, Scott D Lane, Eric Boerwinkle, Jair C Soares
Faculty, Staff and Student Publications
IMPORTANCE: People with major psychiatric disorders are more likely to have comorbidities associated with worse outcomes of COVID-19. This fact alone could determine greater vulnerability of people with major psychiatric disorders to COVID-19.
OBJECTIVE: To assess the odds of testing positive for and mortality from COVID-19 among and between patients with schizophrenia, mood disorders, anxiety disorders and a reference group in a large national database.
DESIGN, SETTING, AND PARTICIPANTS: This cross-sectional study used an electronic health record data set aggregated from many national sources in the United States and licensed from Optum with current and historical data on patients tested …
The "Silent Teacher": Learning By Teaching Via Writing A Verbatim Teaching Script, Kagen Y. L. Lim, Sarah Shi Hui Wong, Stephen Wee Hun Lim
The "Silent Teacher": Learning By Teaching Via Writing A Verbatim Teaching Script, Kagen Y. L. Lim, Sarah Shi Hui Wong, Stephen Wee Hun Lim
Research Collection School of Social Sciences
Learning by teaching others is a potent educational strategy, but its implementation is typically cumbersome. This study (N = 108) investigated “silent teaching”—writing a verbatim teaching script—as a convenient approach for independent learning, while assessing whether the teaching benefit is a production benefit. Learners studied a science text on the Doppler effect using one of three learning methods: (1) generating and studying their own notes (restudying control), (2) preparing to teach and then verbally teaching (verbal teaching), or (3) preparing to teach and then writing a verbatim teaching script (silent teaching). On a conceptual knowledge retention test 1 week later, …
Citalopram For Treatment Of Cocaine Use Disorder: A Bayesian Drop-The-Loser Randomized Clinical Trial, Robert Suchting, Charles E Green, Constanza De Dios, Jessica Vincent, F Gerard Moeller, Scott D Lane, Joy M Schmitz
Citalopram For Treatment Of Cocaine Use Disorder: A Bayesian Drop-The-Loser Randomized Clinical Trial, Robert Suchting, Charles E Green, Constanza De Dios, Jessica Vincent, F Gerard Moeller, Scott D Lane, Joy M Schmitz
Faculty, Staff and Student Publications
BACKGROUND: Medication development research for cocaine use disorder (CUD) has been a longstanding goal in addiction research, but has not resulted in an FDA-approved treatment. Rising cocaine use rates underscore the need for efficient adaptive designs. This study compared differences between two doses of the selective serotonin reuptake inhibitor (SSRI) citalopram (versus placebo) on duration of cocaine abstinence and applied adaptive decision rules to select the 'best efficacy' dose.
METHODS: A double-blind, placebo-controlled, randomized Bayesian drop-the-loser (DTL) trial with three arms compared placebo to citalopram 20 mg and 40 mg. Adults (N = 107) with CUD attended thrice-weekly clinic visits …