Psychology Commons^™

Abnormal Dendritic Maturation Of Developing Cortical Neurons Exposed To Corticotropin Releasing Hormone (Crh): Insights Into Effects Of Prenatal Adversity?, Megan M. Curran, Curt A. Sandman, Elysia Poggi Davis, Laura M. Glynn, Tallie Z. Baram

Psychology: Faculty Scholarship

Corticotropin releasing hormone (CRH) produced by the hypothalamus initiates the hypothalamic-pituitary-adrenal (HPA) axis, which regulates the body’s stress response. CRH levels typically are undetectable in human plasma, but during pregnancy the primate placenta synthesizes and releases large amounts of CRH into both maternal and fetal circulations. Notably, placental CRH synthesis increases in response to maternal stress signals. There is evidence that human fetal exposure to high concentrations of placental CRH is associated with behavioral consequences during infancy and into childhood, however the direct effects on of the peptide on the human brain are unknown. In this study, we used a …

An Investigation On The Neural Correlates Of Testing Encoding And False Memories, Seth Spencer, Brock Kirwan

Journal of Undergraduate Research

Memory is an essential component for day to day living. Recognition memory in the brain has been associated with specific neural structures such as the medial temporal lobe (MTL), including the hippocampus and the adjacent MTL cortex [1]. The hippocampus is known for its ability to encode and retrieve memories through the distinct processes of pattern separation and pattern completion [2]. Pattern separation is the process of separating two similar stimuli to create distinct memories (i.e. discerning which of 2 similar toothbrushes belongs to you). Pattern completion is the retrieval of an old representation given a noisy or degraded cue …

Meth Causes Expression Of 8-Ohg In The Addiction Pathway And Leads To Increased S-Glutathionylation Of The Vesicular Monoamine Transportor Via The Sigma Receptor, Taylor Hyde, Scott Steffensen

Journal of Undergraduate Research

Methamphetamine (METH) is a highly addictive drug of abuse and which results in serious financial, societal, and individual consequences in the United States. In 2005, METH abuse costs the country billions dollars each year. Societal and individual costs as a result of METH use are also high. Knowing how METH acts in the brain is a significant step in developing a pharmocotherapeutic treatment for METH addiction.

Comparing The Effects Of Tredmill Desks And Cycling Desks On Cognitive Performance, Nicholas Randall, Michael Larson

Journal of Undergraduate Research

Sedentary lifestyle and obesity are growing concerns that are responsible for at least 300,000 premature deaths and $90 billion spent on health care per year in the United States (Manson et al., 2004). Many jobs today contribute to a sedentary lifestyle by requiring prolonged periods of sitting. Recent studies show that breaks in sedentary time results in less metabolic risk and a smaller waistline (Healy et al., 2011). Treadmill desks (desks that enable individuals to walk at a slow speed while working) along with cycling desks (workstations where individuals can cycle at a slow speed while working) have been shown …

Oxytocin And Infant Development: A Study Of The Genetic Underpinnings Behind Social Behavior In Rhesus Macaques, Spencer Waters, James Dee Higley

Journal of Undergraduate Research

It is widely accepted that the neuropeptide oxytocin helps mediate pro-social behavior and bonding between humans as well as other primates. Current genetic research has shown a link between variants in the oxytocin receptor gene (OXTR) and measures of social skills in humans. Demonstrating a link between oxytocin genotype and sociality, implies biological underpinnings for social bonding and affiliation in both human and nonhuman primates, suggesting that neurophysiological mechanisms may function to modulate a wide variety of social behaviors.

Effects Of Relationship Quality On Daily Ambulatory Blood Pressure, Kyle Eversole, Wendy Birmingham

Journal of Undergraduate Research

Positive spousal support and relationships that are high in positivity are beneficial in terms of health-outcomes, including lower clinical and ambulatory blood pressure, an indicator of cardiovascular disease risk. Such positive relationships have been associated with lower mortality and morbidity. Conversely, relationships with more negative social interactions have been shown to cause high stress. This stress can cause both psychological and physiological problems, including higher resting and ambulatory blood pressure. In fact, some studies suggest that remaining single is more beneficial than a negative marriage or relationship. However, most marriages are not strictly positive or strictly negative, but rather, a …

Role Of Sigma Receptors In Low-Dose Methamphetamine Modulation Of Dopamine Release In The Nucleus Accumbens, Gilbert Marchant, Scott Steffensen

Journal of Undergraduate Research

Methamphetamine (METH) is an addictive drug of abuse and METH use is a growing problem in the United States. The current dogma states that psychostimulants such as METH attack the mesocorticolimbic dopamine (DA) system, leading to abnormally high DA release when drugs of abuse are taken (Volkow et al., 2004). A key target area of the mesocorticolimbic system is the nucleus accumbens (NAc). Specifically, DA release in the NAc has been associated with reward and motivation (Oleson et al. 2012).

Assessing Diagnostic Capacity Of Event-Related Potentials In Mild Alzheimer’S Disease, Jack Silcox, Bruce Brown

Journal of Undergraduate Research

Alzheimer’s disease is a progressive neurodegenerative disease that always results in death. Unfortunately, the death that eventually comes is preceded by vicious symptoms. A patient with the disease slowly begins to lose memory and other cognitive abilities, robbing a person of their mind and life.

Alzheimer’s disease is becoming a major public health problem (Blennow, de Leon, & Zetterberg, 2006). In 2006, it was estimated that about one quarter of people of above the age of 85 years suffer from Alzheimer’s disease (Ferri, Prince, Brayne, Brodaty, Fratiglioni, Ganguli,… Scazufca). Because of how destructive this disease is to individuals, families and …

Responses To Intimate Partners’ Attempts To Change Health Behavior: The Role Of Readiness, Kieran T. Sullivan, Lauri A. Pasch, Meredith Schreier, Melissa Healy

Psychology

Intimate partners seeking to influence one another’s health may do so by providing support for positive health behavior and attempting to change negative health behavior (social control). Research findings examining the effectiveness of intimate partners’ attempts to influence health behavior are mixed however, and the purpose of the present research is to examine individuals’ responses to hypothetical health behavior influence attempts by an intimate partner. Specifically, we examine the role of readiness to change, cognitive appraisals, and affective responses to partner change attempts. Undergraduate students (n = 185) who reported infrequent exercise or unhealthy eating habits were asked to …

Women’S Autonomy And The Effect On Family Planning In Nepal, Margo Anderson (Taylor), Scott Sanders, Renata Forste

Journal of Undergraduate Research

In 2010, maternal death rates globally reached as high as 210 per 100,000 (United Nations, 2013) and resulted in part from a lack of maternal health services. Maternal health services like family planning play a critical role in improving women’s reproductive health in developing countries (Bhatia and Cleland, 1995). Today there are an estimated 225 million women in developing countries that would choose to delay or stop childbearing but are not using any method of contraception (World Health Organization [WHO], 2015). Linked to low contraceptive use, women in these regions also have low levels of autonomy. These male-dominated regions place …

Effects Of Tetrabenazine On Basal Methamphetamine, Taylor Tribett, Scott Steffensen

Journal of Undergraduate Research

It is easy to see how much METH hurts the lives of its users and leads to high costs for society. Methamphetamine abuse is linked to higher healthcare costs, child abuse, and higher rates of theft and incarceration (Dobkin & Nicosia, 2009). Additionally, prescriptions for amphetamines (which are theorized to work by the same mechanisms) almost doubled in the United States between 2006 and 2011 (Sembower, Ertischek, Buchholtz, Dasgupta, & Schnoll, 2013). As the presence of these drugs becomes more widespread, the number of those at risk for abuse and addiction increases as well. In order to develop pharmacological treatments …

Habituation To Electronic Security Warnings, Corinne Devault, Brock Kirwan

Journal of Undergraduate Research

Habituation is the phenomenon that exhibits itself after repeated exposure to a stimulus; the brain response to it is decreased. This is seen in many different mediums, like tastes, touch, sound, etc., and thus could be observed in experiencing electronic security warnings as well. The brain needs constant vigilance when seeing warnings because large amount of personal information are saved on computers and other forms of technology. Ignoring a warning after it has appeared once or twice could result in a huge breach of information. Thus, it is important to study patterns of habituation of security warnings. There have been …

S-Glutathionylation Of Vmat By Acute Methamphetamine, Spencer Mccarthy, Scott Steffensen

Journal of Undergraduate Research

Methamphetamine (METH) has long been regarded as a potent addictive drug and psychostimulant. The addictive effects can be localized to the VTA, specifically activity of dopaminergic neurons in the nucleus accumbens (NAc). Overactivity of these neurons results in the pleasurable and addictive of METH. Various theories have been proposed as to the mechanism of this excess dopamine release; including a role for reactive oxygen species. In a recent publication, our lab has already demonstrated that METH induces the formation of reactive oxygen species (ROS) in the axon terminals of dopaminergic neurons in the nucleus accumbens and that blocking the formation …

The Role Of Peripheral Mechanisms On Da Enhancement In The Rodent Brain, Christian Carr, Scott Steffensen

Journal of Undergraduate Research

Dopamine is an important brain neurotransmitter regarding brain disorders such as substance abuse, Schizophrenia, Parkinson’s disease, attention deficit hyperactivity disorder (ADHD), and Restless Leg Syndrome (RLS). Dopamine neurons in the ventral tegmental area (VTA) and substantia nigra (SN) are inhibited by DA via DA D2 autoreceptor (D2R) activation (Adell and Artigas, 2005). D2R expression in the brain is a well-known biomarker for brain DA levels, drug abuse, and dependence. Many previous studies have demonstrated that D2R expression is directly proportional to DA levels in the brain. Thus, D2Rs are highly responsive to brain levels. This provides an aid in diagnosing …

The Role Of Dopamine In Vasocontricting Cytokines And Restless Leg Syndrome, Jared Peterson, Scott Steffensen

Journal of Undergraduate Research

Restless Legs Syndrome (RLS) is characterized by strong and often unpleasant urges to move ones legs while at rest and affects approximately 10% of the U.S. population1. The exact cause of RLS is not known, and the mechanism by which the urges are generated is poorly understood. One theory proposes that decreased oxygenation of tissues caused by increased levels of vasoconstricting cytokines may be the cause of these urges. The purpose of this project was to investigate the role that blood dopamine (DA) plays in this mechanism.

Primed For Porn, Investigating The Nuanced Relationship Between Problematic Pornography Consumption And Impulse Control, Celeste Hook, Scott Braithwaite

Journal of Undergraduate Research

As pornography becomes infinitely more accessible through the internet, the number of consumers increases at a rapid rate. Pornography abuse is shown to be a subcategory of hypersexuality (Grubbs, Volk, Exline, & Pargament, 2015), which is defined in the DSM-V as “a repetitive and intense preoccupation with sexual fantasies, urges, and behaviors, leading to adverse consequences”. Hypersexual behaviors have been linked to poorer impulse control (Miner et al., 2009; Prause, Steele et al., 2015; Reid, Cooper, Prause, Li, & Fong, 2012), and poorer impulse control has been related to many addictive behaviors such as substance abuse (Hardy, Steelman, Coyne, & …

Mri Tissue-Based Intensity Standardization For Multi-Site Neuropsychological Outcome Studied: Problems And Potential Solutions, Trevor Huff, Erin Bigler

Journal of Undergraduate Research

In this era of the human connectome, automated image analysis techniques, and large scale multi-site neuroimaging databases examining neuropsychological outcome across a broad spectrum of neurological and neuropsychiatric disorders, there is a particular need to address how to combine neuroimaging studies that use different volumetric sequences or Magnetic Resonance Imaging (MRI) studies performed on different platforms. Currently, there is a large volume of studies that utilize data from multiple scanning locations. This data, while important, cannot reliably be used for comparisons without taking into account the various differences that exist between MRI equipment. The purpose of this study is to …

Interrogation Techniques In South Korea: What Happens In A Korean Interrogation Room?, Hyunjoo Lee

Student Theses

Recently, South Koreans have realized that, due to the techniques used during police investigations, suspects might often commit suicide or confess to crimes that they did not commit. Unfortunately, many studies in Korea are retrospective with regard to false confessions (i.e., case study), and no systematical research studies have been conducted on how Korean police officers interrogate suspects. To prevent events in which potentially guilty suspects are treated inhumanely and innocent suspects falsely confess, self-reported surveys were administered to 86 Korean police officers to systematically analyze how Korean police officers prepare for interrogations (e.g., interrogation training session attendance), how they …

The Effect Of Chronic Ethanol On Vta Gaba Neurons, Stephanie Bair, Scott Steffensen

Journal of Undergraduate Research

The current accepted model for addiction in the brain is the dysregulation of dopamine (DA) in the mesolimbic pathway, which begins in the ventral tegmental area (VTA) and projects to the nucleus accumbens (NAc). DA neurons originate in the VTA and project to the NAc where they release DA. Dopamine neurons are typically regulated locally by inhibitory gamma-aminobutyric acid (GABA) neurons in the VTA. Because GABA neurons in the VTA regulate DA neurons, we conclude that changes in VTA GABA neurons will affect DA release in the NAc underlying addictive behaviors, especially reward seeking.

The Need For An Aural Memory Test Baseline, Eric Brighton, Brock Kirwin

Journal of Undergraduate Research

Visual pattern separation is the ability of an individual to correctly distinguish between images that they have already seen, images that are very similar but not identical, and novel images. Over the last eight years visual pattern separation has come to be well accepted as a measure of an individual’s ability to form long-term memories. Studies have been conducted to see the effects of aging, exercise, depression and anxiety among other things on their ability to do the pattern separation task (Shelton et. al 2013) (Holden et. al 2013). This has been a very useful metric so far, but by …

Mnemonic Mechanisms For The Mundane: A Longitudinal Approach, Athena Howell, Brock Kirwan

Journal of Undergraduate Research

My project focused on the neural activity associated with memory consolidation, particularly the role of pattern separation and pattern completion over an extended period of time. Pattern separation occurs when the brain successfully encodes similar experiences into distinct memories (Deng et al. 2003); for instance, pattern separation allows you to correctly remember what you had for dinner last night as opposed to the night before last. Pattern completion, on the other hand, occurs when you reconstruct a memory from a partial memory (e.g. when asked what you ate last Wednesday night, you respond with the meal you consumed last Tuesday …

Methamphetamine-Induced Melanization In Dopamine Cell Culture, Rebecca Oliphant, Scott Steffensen

Journal of Undergraduate Research

Dopamine (DA) neurons are at the core of many highly-researched diseases. Dopaminergic neuronal degeneration has been linked to oxidative stress, a state that occurs when high levels of normally-occurring reactive oxidative species (ROS) are formed. Depending on the location of such degradation, the result could be either Parkinson’s disease or the very common state of addiction and withdrawal.

Neuromelanin is a dark polymer pigment found on some catecholaminergic neurons and contains a stable radical that is able to inactivate ROS and possibly protect DA neurons from degradation. The mechanism for spontaneous melanization is unknown, but an understanding of this process …

What Happens When Remember The Wrong Thing: The Effects Of False Recognition On Memory Performance, Amanda Ellgen, C. Brock Kirwan

Journal of Undergraduate Research

Our long-term memory system has the impressive ability to form unique representations of events and later retrieve those distinct events with minimal interference from similar events. For example, you may park in the same parking lot everyday, but in a different spot each time. Most days, you can remember specifically where you are parked even though each encounter is very similar and thus might interfere with all the others. Computational models of brain functioning propose that this ability depends on the complementary processes of pattern separation and pattern completion. Pattern separation is the process whereby overlapping representations (of, for example, …

An Open Source Function Utilizing Random Field Theory For Mri Analysis, Zachary Christensen, Erin D. Bigler

Journal of Undergraduate Research

When looking at an MRI scan of the brain one is actually viewing millions of voxels (three dimensional pixels) that represent individual groups of signals produced by the MRI machine. Therefore, each voxel is representative of the brains composition at that point in three dimensional space or metabolic activity (as is the case in functional MRI). These qualities are utilized in research to give anatomically meaningful comparisons of the brain between individual test subjects. Doing so involves the process of mass univariate testing and produces a single statistical value at each voxel representing the univariate test (i.e. a tvalue). However, …

Acute Effects Of Exercise On Aggregate Appetite Hormones, Aaron Miller, Chad Jensen

Journal of Undergraduate Research

Leptin and ghrelin are two hormones involved with suppressing satiety and meal initiation. The primary aim of this study was to evaluate the effects of acute exercise duration of 30 and 60 minutes on the total levels of leptin and ghrelin.

Temporality In Phenomenology: Utilizing The Principles In Practice For Significance Of A Sex Research, Ka Wing Kevin Kwan

The Qualitative Report

This article aims to demonstrate how the researcher can utilize the principle of temporality in phenomenology as a method to explore and to reveal the human experience through its application in sex research. Although phenomenological studies have been increasingly adopted for qualitative inquiry in the field of social science, the idea of the horizon of temporality and its practical utilization is rarely demonstrated explicitly. In this study, the researcher has investigated the interpretation of marital experience of Chinese spouses in Hong Kong who have been assessed with sexual dysfunctions with attention to the couples’ perspectives. Having adopted a synthetic qualitative …

Coping With Micro-Stressors: How Do I Work My Smart Tv?, Jasmin Tahmaseb-Mcconatha

Psychology Faculty Publications

How do I work my Smart TV? What can we do about micro-stressors? Micro-stressors present ongoing daily challenges that threaten the aging self.

Group Decision-Making From An Evolutionary/Adaptationist Perspective, R. Scott Tindale, Tatsuya Kameda

Psychology: Faculty Publications and Other Works

Over the 20 years that Group Processes & Intergroup Relations has been in existence, evolutionary theory has begun to play a larger role in our understanding of human social behavior. Theory and research on group decision-making is no exception and the present paper attempts to briefly highlight how an evolutionary/adaptationist perspective has informed our understanding of how groups reach consensus and make collective choices. In addition, we attempt to show that humans are not the only species that use group processes to make important choices. Looking for similarities and continuities among research domains with different species should lead to a …

The Altruistic Self, Nathan Dougherty

Dialogue & Nexus

Altruism as a purely naturalistic phenomenon self-defeats the term altogether; however, theology also makes unsubstantiated claims that some behaviors are purely selfless. I will first define various conceptual forms of altruism and then offer explanations of the term from neurological, evolutionary and psychological investigations. Despite the position that altruism can be reduced to a fantastical impossibility bearing neither the arms of science nor theology, it is also a fallacy to separate it from a religiously derived supernatural altruism that carries no implications for the realm of morality.

A New Taxonomy Of Altruism In Terms Of Prosocial Behaviors, Kristin Kaiser

Dialogue & Nexus

The definition of altruism has been studied, explained, and even confused by many scholars in various fields. The term itself has been inappropriately used to describe prosocial behaviors that do not fall within the definition of altruism. An evaluation of Grant Ramsey’s taxonomy of altruism, which includes biological altruism, psychological altruism, and helping altruism, proves that it is not adequate in categorizing organism’s behaviors. A new taxonomy, with the branches of kin selection, reciprocity, and aesthetic altruism, is presented and explained to clarify the definition of altruism and alleviate confusion about how to describe prosocial behaviors. Both naming systems are …