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2014

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Articles 211 - 240 of 409

Full-Text Articles in Legal Studies

An Exploratory Examination Of A Prison Disciplinary Process: Assessing Staff And Prisoner’ Perceptions Of Fairness, Ann Marie Rocheleau Apr 2014

An Exploratory Examination Of A Prison Disciplinary Process: Assessing Staff And Prisoner’ Perceptions Of Fairness, Ann Marie Rocheleau

Qualitative Criminology (QC)

There has been scant research on how prison disciplinary processes work in comparison to the myriad of studies on individual, situational, and prison-level factors associated with prison misbehavior. This exploratory research delved into staff and prisoners’ perceptions of a prison system’s disciplinary process. Using in-depth interviews with 25 staff and 25 prisoners as well as direct observation of classification and disciplinary hearings, this research primarily focused on perceptions of fairness. It uncovered those features of the disciplinary process that prisoners and some staff assessed as problematic and unfair. These included: the nature, consistency, and investigation of disciplinary reports, the use …


Duran, Robert J., Gang Life In Two Cities: An Insider’S Journey, Robert Donald Weide Apr 2014

Duran, Robert J., Gang Life In Two Cities: An Insider’S Journey, Robert Donald Weide

Qualitative Criminology (QC)

"In his newly published book, former gang member and probation officer Robert J. Duran provides both a compelling comparative ethnography of gang life in two middle American cities, Denver, Colorado and Ogden, Utah, as well as a needed critical analysis of both the historical and contemporary roles of colonial oppression and law enforcement practices and policies that have contributed to the formation and perpetuation of gang identities in the barrios of those cities. Although neither cites the other’s work, I think it is fair to cast Duran’s book as a counterpart to Michelle Alexander’s celebrated work The New Jim Crow …


Howard S. Becker, Outsiders: Studies In The Sociology Of Deviance, Kenneth D. Tunnell Apr 2014

Howard S. Becker, Outsiders: Studies In The Sociology Of Deviance, Kenneth D. Tunnell

Qualitative Criminology (QC)

"While recently reviewing a manuscript submission for a sociology journal and noticing Becker’s (1963) appearance in the body of the text, I discovered, when skimming the references, that the citation read “The Outsiders.” I remember wondering just how familiar the authors may have been with Outsiders or if they had actually read it – given that they got the title wrong. After all, Outsiders has become one of those books that simply must be cited. And, with growing interest among younger scholars in field research, deviant groups, cultural criminology and inductive analysis, Outsiders has become symbolic of good work that …


A Moral Panic? A Content Analysis Of Prominent Newspapers And Their Portrayal Of Tik Addiction, Chiara Keune Apr 2014

A Moral Panic? A Content Analysis Of Prominent Newspapers And Their Portrayal Of Tik Addiction, Chiara Keune

Theses and Dissertations

The rise of tik (methamphetamine) in the Western Cape of South Africa was an issue of contention for government and health care officials. Tik is the label given to the homemade crystal methamphetamine in South Africa, and the primary substance of abuse for many addicts seeking help. This paper sets out to examine tik from a moral panic perspective to understand if tik is an actual threat or a moral panic phenomenon. Two prominent newspapers were examined using content analysis. The Cape Times and Cape Argus were sampled to understand the social construction of tik. A moral panic is simply …


Exploring Racial Disparities Of Victimization In Three Core Dimensions Of Stand Your Ground Law: The Case Of Florida, Toyin Isijola Apr 2014

Exploring Racial Disparities Of Victimization In Three Core Dimensions Of Stand Your Ground Law: The Case Of Florida, Toyin Isijola

Dissertations, Theses and Capstone Projects (Full IR Collection)

‘Stand Your Ground’ (SYG) laws continue to be a source of controversy, even more so after the shooting death of an unarmed black teen in Florida, Trayvon Martin. Upon abolishing the ‘duty to retreat,’ the law has been criticized for allowing ordinary citizens to carry out vigilante justice. The media has shed light on a few incidents which indicate that young black males may be vulnerable to SYG laws. Prior research on SYG laws have mostly focused on racial disparities in the outcomes of cases and deterrence effects of the law, but this research should contribute to the study of …


An Experimental Study To Quantify Error Rates Resulting From Measurement Deviation In Area Of Origin Reconstructions Of Blunt Force Impact Patterns, Mark Davison, Timothy Palmbach Apr 2014

An Experimental Study To Quantify Error Rates Resulting From Measurement Deviation In Area Of Origin Reconstructions Of Blunt Force Impact Patterns, Mark Davison, Timothy Palmbach

Forensic Science Publications

The intent of this study was to attempt to quantify error associated with the measurements required in area of origin reconstructions resulting from the analysis of blunt force impact patterns. Mathematical tables were constructed in order to examine trends associated with changing width and length ratios and the influence of impact angle change and area of convergence deviations. The analysis of the trends enabled informed stain selection, mitigating potential error. The analysis of the influence of stain measurement error and gamma angle error was conducted by reconstructing experimentally created blunt force impact patterns using the Tangent Method, comparing the resulting …


Location, Location, Location, The Impact Of Registered Sex Offenders On Home Sale Prices: A Case Study Of Mclean County, Illinois, John C. Navarro Apr 2014

Location, Location, Location, The Impact Of Registered Sex Offenders On Home Sale Prices: A Case Study Of Mclean County, Illinois, John C. Navarro

Theses and Dissertations

Borrowing from broken windows theory, this paper addresses the impact of sex offenders' residences on neighborhood's property values in McLean County, Illinois. Three data sets were combined to explore the relationship: the addresses of registered sex offenders (RSOs) in McLean County, Illinois, the location and property characteristics of homes sold in McLean County between December 2012 to December 2013, and variables from the 2010 U.S. Census. ArcGIS was utilized to create buffers up to 0.2 of a mile around a sold home to measure the concentration of RSOs and sexual predators (SPs) and to calculate the distance from the nearest …


Promoting Justice, Peace, And Understanding Through Partnerships And Dialogue, Center For Peace, Democracy, And Development, University Of Massachusetts Boston Apr 2014

Promoting Justice, Peace, And Understanding Through Partnerships And Dialogue, Center For Peace, Democracy, And Development, University Of Massachusetts Boston

Office of Community Partnerships Posters

The Center for Peace, Democracy and Development (CPDD) promotes conflict resolution, democracy, economic development, education building, media development, and legal and judicial reform through partnerships and training programs across the globe. We offer academic and practical expertise across the spectrum of conflict management and democratic governance. Moreover, we mentor the next generation of peace and democracy builders from the UMass Boston student body who actively participate in many of our initiatives. The Restorative Justice Mediation Project (RJUMP) is a university-based program that aims to provide restorative justice services, education and training to the Suffolk County law enforcement community, department of …


Prison Poetry Group, Master Of Fine Arts Creative Writing Program, College Of Liberal Arts, University Of Massachusetts Boston, Bay State Correctional Center Apr 2014

Prison Poetry Group, Master Of Fine Arts Creative Writing Program, College Of Liberal Arts, University Of Massachusetts Boston, Bay State Correctional Center

Office of Community Partnerships Posters

Beginning in September 2012, a graduate student enrolled in UMass Boston’s MFA Creative Writing Program served as the volunteer instructor for a Poetry Group at Baystate Correctional Center. Through creative development and community discussion, this program, which operates during the academic year (September-May), facilitates positive behavioral change in order to eliminate violence, victimization, and recidivism.


From Death To Near-Death: The Fate Of Serious Youthful Offenders After Roper V. Simmons, Christopher A. Mallett Apr 2014

From Death To Near-Death: The Fate Of Serious Youthful Offenders After Roper V. Simmons, Christopher A. Mallett

Social Work Faculty Publications

The United States juvenile death penalty was abolished in 2005 when the Supreme Court, in Roper v. Simmons, found this punishment to be cruel and unusual and in violation of the Constitution’s Eighth Amendment.1 This decision was the final step in ending the death sentence for those under the age of eighteen. While this sentence is no longer an option for retributively-inclined states, many serious youthful offenders continue to meet similar, and in some ways, comparably difficult fates. These fates include the wholesale transfer of serious youthful offenders to the criminal courts2 and the subsequent incarceration of tens of …


Urban Politics And The Judiciary: Treating Courts As Endogenous, Christopher Shortell Apr 2014

Urban Politics And The Judiciary: Treating Courts As Endogenous, Christopher Shortell

Political Science Faculty Publications and Presentations

The study of urban politics often focuses on the ability of urban regimes to successfully pursue their interests and goals. However, scholars of urban politics only peripherally consider the role that courts play. And when courts are incorporated, they are treated as exogenous to the political system. This paper argues for the importance of treating the judiciary as endogenous to the local political system. Courts are themselves political institutions and should be understood as such in the study of politics at the local level. Doing so offers several benefits, including accounting for the ways in which state-level preferences operate as …


Applying Sex Offender Registry Laws To Juvenile Offenders: Biases Against Adolescents From Stigmatized Groups, Jessica M. Salerno, Margaret Stevenson, Cynthia J. Najdowski, Tisha R.A. Wiley, Bette L. Bottoms, Liana Peter-Hagene Apr 2014

Applying Sex Offender Registry Laws To Juvenile Offenders: Biases Against Adolescents From Stigmatized Groups, Jessica M. Salerno, Margaret Stevenson, Cynthia J. Najdowski, Tisha R.A. Wiley, Bette L. Bottoms, Liana Peter-Hagene

Psychology Faculty Scholarship

The need to protect children from dangerous sex offenders has led to policies that require juvenile sex offenders to register on public online registries. It is important to determine the implications of these laws for the wellbeing of child victims and also for juvenile offenders on these registries. Is the application of these laws—designed for adult offenders—to juveniles appropriate, necessary, and supported by public sentiment? The chapter reviews current sex offender registration policies and psychological research addressing whether the assumptions underlying these laws are supported by research, public sentiment toward these laws, factors that might drive biases against stigmatized youth …


Nebraska Transcript (University Of Nebraska College Of Law), Volume 47, Number 1, Spring 2014 Apr 2014

Nebraska Transcript (University Of Nebraska College Of Law), Volume 47, Number 1, Spring 2014

Nebraska Transcript

Dean’s Message

Faculty Updates
Profile: Bill Lyons
Faculty Notes
Faculty Lead the Way at International Conference
Schaefer Publishes White Paper
Pearlman, Dority Baker Publish Bibliography

Feature:
International Perspectives Introduced into 1L Curriculum

Around the College
Pearce Named New Assistant Dean for Student Affairs & Administration
Brooks, ’15, Spends Summer in Thailand
Donald Examines Impact of Technology on Profession
Carter Delivers Lane Lecture
CLEP Brings Law-Related Education to Schools
Alumni Volunteers Provide Valuable Time to CSO
Reflections on Gideon
Student Group Promotes Rural Connections
December Commencement Pictorial

Our Alumni
Nordhues Leads Development Office
McIlnay: Alumni Master
Veltchkov: Bulgaria’s Deputy Foreign …


Juvenile Diversion Programs: High-Risk Youth And Their Effect On Offense Targeting, Chelsey R. Warner Apr 2014

Juvenile Diversion Programs: High-Risk Youth And Their Effect On Offense Targeting, Chelsey R. Warner

Political Science Theses and Capstones

One of the largest problems that plague the juvenile justice system today is how to better handle juvenile crime without causing the juvenile to revert back to that behavior, but still helping them understand and acknowledge the crime they have committed. The state of Minnesota has created juvenile diversion programs as an attempt to aid in that endeavor. These programs however are under researched. The goal of this article is to shed some light on what those programs look like and how some counties programs vary from other programs on other counties; specifically focusing on the variation between offense-targeting for …


Prevention And Management Of Stress In Policing: A Review Of The Literature, Portland State University. Criminology And Criminal Justice Senior Capstone Apr 2014

Prevention And Management Of Stress In Policing: A Review Of The Literature, Portland State University. Criminology And Criminal Justice Senior Capstone

Criminology and Criminal Justice Senior Capstone Project

Working as a police officer can be a rewarding job, but it can also be a stressful one. Policing is one of the few professions where individuals deal with many stressors, which exceed the usual expectations of society. Although there is no way to eliminate stress and the burnout it can cause, there are methods law enforcement agencies can utilize to help officers prevent stress from worsening and to make it more manageable. This literature review contains information to help police agencies train officers about prevention and management of stress in the workplace. It is based on 29 studies from …


Natural Law, Equality, And Same-Sex Marriage, Perry Dane Apr 2014

Natural Law, Equality, And Same-Sex Marriage, Perry Dane

Buffalo Law Review

No abstract provided.


Maine Crime & Justice Data Book 2014, George Shaler Mph Apr 2014

Maine Crime & Justice Data Book 2014, George Shaler Mph

Justice Policy

The 2014 Maine Crime and Justice Data Book presents a portrait of crime and justice indicators in the state, using the most recent public safety, corrections, and court data available for Maine. The reports looks at ten year trends in Maine, compares Maine figures with data from other northern New England states and the United States, and presents some county level findings as well.


Program And Proceedings: Nebraska Academy Of Sciences 1880–2014, 134th Anniversary Year, One Hundred-Twenty-Fourth Annual Meeting, April 11, 2014 Apr 2014

Program And Proceedings: Nebraska Academy Of Sciences 1880–2014, 134th Anniversary Year, One Hundred-Twenty-Fourth Annual Meeting, April 11, 2014

Nebraska Academy of Sciences: Programs and Proceedings

Program

Aeronautics and Space Science

Collegiate Academy: Biology

Chemistry and Physics

Collegiate Academy: Chemistry and Physics

Applied Science and Technology

Biological and Medical Sciences

Aeronautics and Space Science, Poster Session

Anthropology

Maiben Memorial Lecture: "Education, Careers and Opportunities in Engineering and Metallurgy in Nebraska," Terry Rasmussen, Nucor Steel, Norfolk, Nebraska

Teaching of Science and Mathematics

Anthropology

Earth Science


Volume 06, Kristen Gains, Amanda Willis, Holly Backer, Monika Gutierrez, Cara O'Neal, Sara Nelson, Sasha Silberman, Jessica Beardsley, Jamie Gardner, Edward Peeples, Matthew Sakach, Tess Lione, Emily Wilkins, Kelsey Holt, Jessica Page, Jamie Clift, Charles Vancampen, Gilbert Hall, Jenny Nehrt, Kasey Dye, Amanda Tharp, Jamie Leeuwrik, Ashley Mcgee, Emily Poulin, Michael Kropf, Nick Pastore, Austin Polasky, Morgan Glasco, Laura L. Kahler, Melinda L. Edwards, Brandon C. Smith, Mariah Asbell, Cabell Edmunds, Amelia D. Perry, Alyssa Hayes, Irina Boothe, Perry Bason, James Early Apr 2014

Volume 06, Kristen Gains, Amanda Willis, Holly Backer, Monika Gutierrez, Cara O'Neal, Sara Nelson, Sasha Silberman, Jessica Beardsley, Jamie Gardner, Edward Peeples, Matthew Sakach, Tess Lione, Emily Wilkins, Kelsey Holt, Jessica Page, Jamie Clift, Charles Vancampen, Gilbert Hall, Jenny Nehrt, Kasey Dye, Amanda Tharp, Jamie Leeuwrik, Ashley Mcgee, Emily Poulin, Michael Kropf, Nick Pastore, Austin Polasky, Morgan Glasco, Laura L. Kahler, Melinda L. Edwards, Brandon C. Smith, Mariah Asbell, Cabell Edmunds, Amelia D. Perry, Alyssa Hayes, Irina Boothe, Perry Bason, James Early

Incite: The Journal of Undergraduate Scholarship

Introduction from Dean Dr. Charles Ross

Caught Between Folklore and the Cold War: The Americanization of Russian Children's Literature by Kristen Gains

Graphic Design by Amanda Willis

Graphic Design by Holly Backer

Prejudices in Swiss German Accents by Monika Gutierrez

Photography by Cara O'Neal

Photography by Sara Nelson

Edmund Tyrone's Long Journey through Night by Sasha Silberman

Photography by Jessica Beardsley

Photography by Jamie Gardner and Edward Peeples

The Republican Razor: The Guillotine as a Symbol of Equality by Jamie Clift

Graphic Design by Matthew Sakach

Genocide: The Lasting Effects of Gender Stratification in Rwanda By Tess Lione and Emily …


Dating Violence On The College Campus: Exploring Student Perception And Awareness, Patrice Gibson Apr 2014

Dating Violence On The College Campus: Exploring Student Perception And Awareness, Patrice Gibson

Undergraduate Theses and Capstone Projects

Dating violence is a crime that plagues college students all over the world. Many students are unaware of what specifically constitutes dating violence and what resources are available to those who are affected by this crime. Colleges and universities tend to have vague or nonexistent rules and regulations regarding dating violence; there is also a lack of education provided to first-year students about dating violence and resources available to them. The present study explored student perception of dating violence and focused on students from small, liberal arts colleges in the central and southwest part of Virginia. Furthermore, this study built …


A Quantitative Examination Of Known Exonernations And The Factors That Have Contributed To The Wrongful Convictions Of Innocents, Meagan Andrea Semmelroth Mar 2014

A Quantitative Examination Of Known Exonernations And The Factors That Have Contributed To The Wrongful Convictions Of Innocents, Meagan Andrea Semmelroth

Theses and Dissertations

Wrongful convictions have been gaining attention both in the public and academic arenas. The knowledge that has been gained about wrongful convictions has been gained mostly by looking at cases of exonerations based on factual innocence. The use of DNA in the adjudication process, mainly in helping to defend and free innocent people brought the detriments of wrongful convictions into the lives of the public through the use of media. Since this time, innocence projects have opened, more cases of exonerations have been found, and more cases of wrongful conviction have been overturned. However, the frequency with which wrongful convictions …


Development Of A Quantitative Real-Time Polymerase Chain Reaction (Rt-Pcr) Assay For Plant Species, Kayla Curtis, Heather Miller Coyle Mar 2014

Development Of A Quantitative Real-Time Polymerase Chain Reaction (Rt-Pcr) Assay For Plant Species, Kayla Curtis, Heather Miller Coyle

Forensic Science Publications

In order to facilitate optimal plant DNA quantitation and identification, an assay has been developed that uses generic plant PCR primers that amplify a region in the chloroplast genome of plant samples. The assay uses the SYBR green detection dye to detect the PCR product with a universal PCR primer set to the large subunit of ribulose bisphosphate carboxylase, rbcL, but can be used with any of the universal barcode primers for land plants (rbcL, matK, trnH, psbA). Standard dilutions of control wheat DNA of varying concentrations were tested to create a standard curve. Several plant DNA extractions of different …


An Enzymatic Method To Process Decomposed Non-Human Bone For Forensic Dna Analysis, Richard Li, Melissa Gaud, Smriti Nair Mar 2014

An Enzymatic Method To Process Decomposed Non-Human Bone For Forensic Dna Analysis, Richard Li, Melissa Gaud, Smriti Nair

Publications and Research

Forensic analysis of DNA from non-human bones can be important in investigating a variety of forensic cases. However, decomposed bone is difficult to process for isolating DNA. In this study, a previously established enzymatic method was utilized to process bone samples that simulate decomposed specimens. Our results demonstrated that this enzymatic processing method is effective for removing decomposed soft tissues and outer surface materials such as mineralized bone connective tissue of bone fragment samples. Our data suggested that this method can be used in the initial sample preparation for cleaning the outer surface of decomposed non-human skeletal fragments. This study …


Resources Matter: The Role Of Social Capital And Collective Efficacy In Mediating Gun Violence, Jennifer Lynne Dean Mar 2014

Resources Matter: The Role Of Social Capital And Collective Efficacy In Mediating Gun Violence, Jennifer Lynne Dean

USF Tampa Graduate Theses and Dissertations

Abstract

This study explains how community activists make use of available social capital and collective efficacy while attempting to mediate gun violence. It specifically focuses on twelve in-depth interviews of activists' perspectives, processes and rationales to alleviate community gun violence, based on informal social control models. Findings suggest activists must establish trust and respect with youth they work with before mediation begins, which is established through similar life experiences or backgrounds. Once a strong bond is established with youth, activists identified five core processes to reduce violence: 1) improve the mindset, 2) provide life skills, 3) assist youth as their …


What Does Performance Theory Have To Teach Us About The Treatment Of Severe And Persistent Mental Illness (Spmi) In Prison?, Kaley Joanne Raskin Mar 2014

What Does Performance Theory Have To Teach Us About The Treatment Of Severe And Persistent Mental Illness (Spmi) In Prison?, Kaley Joanne Raskin

Graduate School of Professional Psychology: Doctoral Papers and Masters Projects

Deinstitutionalization of psychiatric hospitals, which occurred in the 1970's, led to an overwhelming number of mentally ill individuals within jails and prisons. In fact, correctional facilities have become the mainline providers of mentally ill inmates; however, these facilities' primary form of intervention is psychotropic medication. Although beneficial in some instances, when viewed through the lens of Goffman's theories of performance and stigma, simply providing medication promotes the role of mental patient. Arguably, within correctional facilities, medication management assists in maintaining security in the institution (i.e., external change); however, this prohibits the inmate from internal change, which might otherwise be facilitated …


Regulating Sex Work: Assimilation, Erotic Exceptionalism & Beyond, Adrienne D. Davis Mar 2014

Regulating Sex Work: Assimilation, Erotic Exceptionalism & Beyond, Adrienne D. Davis

Women, Gender & Sexuality Studies Faculty Research

Most commentators on sex markets focus on the debate between abolitionists and those who defend and support professional sex work. This paper, instead, looks at debates within the pro-sex work camp, uncovering some unattended tensions and contradictions. It shows that, within this camp, some stress the labor aspect, urging that sex markets perpetuate a "vulnerable population" of workers, similar to others who perform highly risky and/or exploited labor, and should be regulated accordingly. In this view, sex work would be assimilated into other labor. Others, though, take a more anti-regulatory stance. They exceptionalize this form of labor, arguing that because …


The Influence Of Community Context On Social Control: A Multi-Level Examination Of The Relationship Between Race/Ethnicity, Drug Offending, And Juvenile Court Outcomes, Jennifer Peck Mar 2014

The Influence Of Community Context On Social Control: A Multi-Level Examination Of The Relationship Between Race/Ethnicity, Drug Offending, And Juvenile Court Outcomes, Jennifer Peck

USF Tampa Graduate Theses and Dissertations

Studies of the association between race/ethnicity and juvenile court outcomes have found that minority youth often receive disadvantaged outcomes compared to similarly situated Whites, and that community context may condition this relationship. Sampson and Laub's (1993) revised conflict perspective is one theoretical model that can potentially explain the social control of youth throughout juvenile justice proceedings. One of the main propositions of Sampson and Laub's (1993) perspective is that communities characterized by underclass poverty and racial inequality will impose greater social control on youth referred to the juvenile court, especially Blacks and youth charged with a drug offense because they …


Juvenile And Adult Involvement In Double Parricide And Familicide In The U.S.: An Empirical Analysis Of 20 Years Of Data, Averi Rebekah Fegadel Mar 2014

Juvenile And Adult Involvement In Double Parricide And Familicide In The U.S.: An Empirical Analysis Of 20 Years Of Data, Averi Rebekah Fegadel

USF Tampa Graduate Theses and Dissertations

The killing of parents and stepparents by biological and stepchildren is a rare event. Incidents involving multiple parricide victims and/or multiple parricide offenders are an even rarer occurrence. The majority of studies on parricide involve a single victim and single offender. Using the National Incident-Based Reporting System (NIBRS), this study identified 603 single-victim, single-offender incidents, 22 single-victim, multiple-offender incidents, 60 single-offender double parricide incidents, 17 multiple-offender double parricide incidents, and 15 familicide incidents over the 20 year period 1990 to 2010. Univariate and bivariate analyses examined parricidal incidents involving single or multiple offenders and single or multiple victims with the …


Key Strains, Anger And Delinquency: The General Strain Theory Test On Sourth Korean Youths From Low-Income Households, Jihye Park, Dae-Hoon Kwak Mar 2014

Key Strains, Anger And Delinquency: The General Strain Theory Test On Sourth Korean Youths From Low-Income Households, Jihye Park, Dae-Hoon Kwak

Graduate Research - Criminal Justice

General Strain Theory: Negative relations of strains create unpleasant emotions (e.g., anger and depression), which lead strained people to commit crimes as their coping methods. Strains are more likely to lead to crimes.


Impact Of Tumour Epithelial Subtype On Circulating Micrornas In Breast Cancer Patients, Peadar S. Waters, Roisin M. Dwyer, Cathy Brougham, Claire L. Glynn, Deidre Wall, Peter Hyland, Maria Duignan, Mark Mcloughlin, John Newell, Michael J. Kerin Mar 2014

Impact Of Tumour Epithelial Subtype On Circulating Micrornas In Breast Cancer Patients, Peadar S. Waters, Roisin M. Dwyer, Cathy Brougham, Claire L. Glynn, Deidre Wall, Peter Hyland, Maria Duignan, Mark Mcloughlin, John Newell, Michael J. Kerin

Forensic Science Publications

While a range of miRNAs have been shown to be dysregulated in the circulation of patients with breast cancer, little is known about the relationship between circulating levels and tumour characteristics. The aim of this study was to analyse alterations in circulating miRNA expression during tumour progression in a murine model of breast cancer, and to detemine the clinical relevance of identified miRNAs at both tissue and circulating level in patient samples. Athymic nude mice received a subcutaneous or mammary fat pad injection of MDA-MB-231 cells. Blood sampling was performed at weeks 1, 3 and 6 following tumour induction, and …