Open Access. Powered by Scholars. Published by Universities.®

Biological and Physical Anthropology Commons

Open Access. Powered by Scholars. Published by Universities.®

Articles 1 - 2 of 2

Full-Text Articles in Biological and Physical Anthropology

Hippocampal Extracellular Potassium Levels And Formation Of Spatial Memory In Response To Retrodialysis Insulin Administration, Gabrielle Shames Dec 2019

Hippocampal Extracellular Potassium Levels And Formation Of Spatial Memory In Response To Retrodialysis Insulin Administration, Gabrielle Shames

Anthropology

Insulin is the most common treatment for hyperglycemia, such as that caused by type 1 or type 2 diabetes mellitus. Insulin causes cellular uptake and storage of glucose to maintain homeostasis and also plays important roles in other systems; an important example is regulation of potassium. In the periphery, insulin administration has been shown to increase the cellular uptake of potassium via Na+/K+ ATPase, leading to hypokalemia. Research in our lab and others has shown that insulin is a key regulator of cognitive function and local metabolism within the hippocampus. To date, however, no studies have examined whether insulin acts …


Bayesian Analysis In Adult Skeletal Age-At-Death Estimation, With Additional Consideration Of Pathological Variables, Jessica L. Campbell Jan 2019

Bayesian Analysis In Adult Skeletal Age-At-Death Estimation, With Additional Consideration Of Pathological Variables, Jessica L. Campbell

Legacy Theses & Dissertations (2009 - 2024)

A common task bioarchaeologists face is to estimate age-at-death in populations that have no corresponding documentation. This poses many challenges, the first of which is that age-at-death is highly variable within and among populations and can be further confounded by genetic and environmental influences, as well as other components of the biological profile. Estimating age-at-death in a historic sample can be even more challenging due to missing age indicators or taphonomic changes that obscure the features. Bayesian Analysis offers the potential to mitigate these challenges and to estimate age-at-death with lower degrees of uncertainty and higher probabilities of increased accuracy …