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Biological and Physical Anthropology Commons

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Publications and Research

Bone histology

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Full-Text Articles in Biological and Physical Anthropology

Pore Extractor 2d: An Imagej Toolkit For Quantifying Cortical Pore Morphometry On Histological Bone Images, With Application To Intraskeletal And Regional Patterning, Mary E. Cole, Sam D. Stout, Victoria M. Dominguez, Amanda M. Agnew Jan 2022

Pore Extractor 2d: An Imagej Toolkit For Quantifying Cortical Pore Morphometry On Histological Bone Images, With Application To Intraskeletal And Regional Patterning, Mary E. Cole, Sam D. Stout, Victoria M. Dominguez, Amanda M. Agnew

Publications and Research

Objectives: Cortical porosity is used as a proxy of bone quality, fragility, and remo- deling activity in anthropological contexts. Histological quantification is limited by time-intensive manual annotation. Pore Extractor 2D is an ImageJ toolkit developed for computer-assisted pore identification and automated pore morphometry. Materials and Methods: Toolkit components include: (1) Utilities for cortical border clearing, (2) Image Pre-Processing: Image contrast enhancement and noise reduction, (3) Pore Extractor: User-directed options for segmenting, closing, and smoothing pore spaces, (4) Pore Modifier: Utilities to expedite manual correction of extracted pore spaces, and (5) Pore Analyzer: Morphometric analyses by pore type and anatomical region. …