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Articles 1 - 3 of 3
Full-Text Articles in Biological and Physical Anthropology
Evidence For A Peak Shift In A Humoral Response To Helminths: Age Profiles Of Ige In The Shuar Of Ecuador, The Tsimane Of Bolivia, And The U.S. Nhanes, Aaron D. Blackwell, Michael D. Gurven, Lawrence S. Sugiyama, Felicia C. Madimenos, Melissa A. Liebert, Melanie A. Martin, Hillard Kaplan, J. Josh Snodgrass
Evidence For A Peak Shift In A Humoral Response To Helminths: Age Profiles Of Ige In The Shuar Of Ecuador, The Tsimane Of Bolivia, And The U.S. Nhanes, Aaron D. Blackwell, Michael D. Gurven, Lawrence S. Sugiyama, Felicia C. Madimenos, Melissa A. Liebert, Melanie A. Martin, Hillard Kaplan, J. Josh Snodgrass
ESI Publications
Background: The peak shift model predicts that the age-profile of a pathogen’s prevalence depends upon its transmission rate, peaking earlier in populations with higher transmission and declining as partial immunity is acquired. Helminth infections are associated with increased immunoglobulin E (IgE), which may convey partial immunity and influence the peak shift. Although studies have noted peak shifts in helminths, corresponding peak shifts in total IgE have not been investigated, nor has the age-patterning been carefully examined across populations. We test for differences in the agepatterning of IgE between two South American forager-horticulturalist populations and the United States: the Tsimane …
Inflammatory Gene Variants In The Tsimane, An Indigenous Bolivian Population With A High Infectious Load, Sarinnapha Vasunilashorn, Caleb E. Finch, Eileen M. Crimmins, Suvi A. Vikman, Jonathan Stieglitz, Michael Gurven, Hillard Kaplan, Hooman Allayee
Inflammatory Gene Variants In The Tsimane, An Indigenous Bolivian Population With A High Infectious Load, Sarinnapha Vasunilashorn, Caleb E. Finch, Eileen M. Crimmins, Suvi A. Vikman, Jonathan Stieglitz, Michael Gurven, Hillard Kaplan, Hooman Allayee
ESI Publications
The Tsimane of lowland Bolivia are an indigenous forager-farmer population living under conditions resembling pre-industrial European populations, with high infectious morbidity, high infection and inflammation, and shortened life expectancy. Analysis of 917 persons ages 5 to 60+ showed that allele frequencies of 9 SNPs examined in the apolipoprotein E (apoE), C-reactive protein (CRP), and interleukin-6 (IL-6) genes differed from some European, African, and north Asian-derived populations. The apoE2 allele was absent, whereas four SNPs related to CRP and IL-6 were monomorphic: CRP (rs1800947, rs3093061, and rs3093062) and IL-6 (rs1800795). No significant differences in apoE, CRP, and IL-6 variants across age …
Father Death And Adult Success Among The Tsimane: Implications For Marriage And Divorce, Jeffrey Winking, Michael Gurven, Hillard Kaplan
Father Death And Adult Success Among The Tsimane: Implications For Marriage And Divorce, Jeffrey Winking, Michael Gurven, Hillard Kaplan
ESI Publications
Human fathers are heavily involved in the rearing of children around the world. While there is great cross-cultural variation, the father is a recognizable role in all populations. This deviates from the standard mammalian pattern of little paternal investment. A logical explanation offered early by evolutionary theorists is that human fathers evolved the capacity for paternal concern because human children are remarkably needy and impose a great encumbrance on the mother (Lancaster & Lancaster, 1983; Lovejoy, 1981). Thus, fathers have greater opportunity to enhance the wellbeing of child and mother, as there is a deeper well of need to fill. …