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Full-Text Articles in Biological and Physical Anthropology
Evolution Of Endurance Running Genes Across Primates, Natalia T. Grube
Evolution Of Endurance Running Genes Across Primates, Natalia T. Grube
Theses and Dissertations
The endurance running hypothesis has emerged as a key idea to explain several unique anatomical, physiological, and genetic features of modern humans—among these features is the evolution of ACTN3 (Bramble & Lieberman 2004, Nature), a gene linked to human athletic performance. An additional gene linked to human endurance performance is ACE. Because endurance running is a uniquely human trait, I predicted that ACE and ACTN3 genes would be evolving adaptively in the human lineage when examined in a wider primatological framework. To test this I compiled ACE and ACTN3 genes from 14 primate species and phylogenetically tested if these genes …