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Social and Behavioral Sciences Commons™
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Full-Text Articles in Social and Behavioral Sciences
Potential Roles Of Abundant Extracellular Chaperones In The Control Of Amyloid Formation And Toxicity, Mark R. Wilson, Justin J. Yerbury, Stephen Poon
Potential Roles Of Abundant Extracellular Chaperones In The Control Of Amyloid Formation And Toxicity, Mark R. Wilson, Justin J. Yerbury, Stephen Poon
Faculty of Science - Papers (Archive)
The in vivo formation of fibrillar proteinaceous deposits called amyloid is associated with more than 40 serious human diseases, collectively referred to as protein deposition diseases. In many cases the amyloid deposits are extracellular and are found associated with newly identified abundant extracellular chaperones (ECs). Evidence is presented suggesting an important regulatory role for ECs in amyloid formation and disposal in the body. A model is presented which proposes that, under normal conditions, ECs stabilize extracellular misfolded proteins by binding to them, and then guide them to specific cell receptors for uptake and subsequent degradation. Thus ECs and their receptors …
Interference Control In Children With Ad/Hd: An Erp And Behavioural Analysis, Sarah Opychane, Stuart J. Johnstone
Interference Control In Children With Ad/Hd: An Erp And Behavioural Analysis, Sarah Opychane, Stuart J. Johnstone
Faculty of Health and Behavioural Sciences - Papers (Archive)
No abstract provided.