Social and Behavioral Sciences Commons^™

Incidence And 5-Year Survival Of Children And Adolescents With Hepatoblastoma In The United States, Justin A Kahla, David A Siegel, Shifan Dai, Philip J Lupo, Jennifer H Foster, Michael E Scheurer, Andras A Heczey

Center for Medical Ethics and Health Policy Staff Publications

Objective: Hepatoblastoma (HB) is the most common pediatric primary malignant liver tumor, its incidence has been increasing worldwide, but recent changes in incidence and outcomes with high population coverage are not well characterized.

Methods: We defined the incidence of HB diagnosed during 2003-2017 from United States Cancer Statistics (USCS) database, and survival during 2001-2016 from the National Program of Cancer Registries (NPCR). Data were stratified by sex, race/ethnicity, age, tumor stage, county population, and diagnosis year. Incidence trends were assessed by calculating average annual percent change (AAPC) using Joinpoint regression. Differences in overall 5-year survival were estimated using Cox regression …

Longitudinal Investigation Of Suicidal Ideation And Associated Factors During Pediatric Acute Lymphoblastic Leukemia Chemotherapy, Kimberly P Raghubar, Tiffany Chambers, Ryan M Hill, Olga Taylor, Marilyn Hockenberry, M Casey Hooke, Pauline Mitby, Ida Ki Moore, Austin L Brown, Michael E Scheurer

Center for Medical Ethics and Health Policy Staff Publications

Objective: This study describes the prevalence of suicidal ideation (SI) during acute lymphoblastic leukemia (ALL) therapy and investigates the influence of clinical factors and physical symptoms on SI.

Methods: The Children's Depressive Inventory (CDI-2) was administered to ALL patients (diagnosed 2012-2017) at start of consolidation, delayed intensification (DI), maintenance cycle 1 (MC1), and maintenance cycle 2 (MC2) in a multi-site study. SI was present if patients endorsed the item "I want to kill myself." Logistic regression models evaluated associations between SI and sociodemographic factors; depressive symptoms; and below average, average, and above average symptom clusters identified using latent class analysis …

Outdoor Thermal Comfort Research In Transient Conditions: A Narrative Literature Review, Yuliya Dzyuban, Graces N. Y. Ching, Sin Kang Yik, Adrian J. Tan, Shreya Banerjee, Peter Jay Crank, Winston T. L. Chow

Research Collection College of Integrative Studies

In recent years, urban planners and designers are paying greater attention to Outdoor Thermal Comfort (OTC) studies due to the imminent threat of the Urban Heat Island and climate change on human health. Historically, indoor thermal comfort research assumed steady-state conditions, centralizing on the concept of thermal neutrality to determine optimal environmental parameters. Such research pivoted to investigating how non-steady-state, transient environmental conditions influence comfort. Recent studies underscore the usefulness of positive alliesthesia in providing a productive framework for OTC evaluation. In this article we first clarify the concepts related to thermal comfort-related terms, scales, and models in the literature. …

Analysing Impacts Of Urban Morphological Variables And Density On Outdoor Microclimate For Tropical Cities: A Review And A Framework Proposal For Future Research Directions, Shreya Banerjee, Ngai Yan Ching, Sin Kang Yik, Yuliya Dzyuban, Peter Jay Crank, Xin Yi Pek, Winston T. L. Chow

Research Collection College of Integrative Studies

Modifying urban morphology, defined as mass, density, and orientation of building stock in cities, are well-known heat mitigation strategies addressing urban heat islands (UHI) at various scales and consequent thermal discomfort. However, varying morphological aspects may have divergent effects on Outdoor Thermal Comfort (OTC) in cities. Unlike UHI, which is derived from urban-rural temperature differences, OTC can be quantified by thermal comfort indices considering the objective assessment of microclimatic variables including air temperature (Ta), relative humidity (RH), mean radiant temperature (TMRT), and wind speed (Va), as well as a subjective assessment of individual perception. In Singapore and other tropical cities, …

Developing Climate Resilient Cities, Winston T. L. Chow

Research Collection College of Integrative Studies

We need to be quicker.

Psychiatric Polygenic Risk Scores: Child And Adolescent Psychiatrists’ Knowledge, Attitudes, And Experiences, Stacey Pereira, Katrina A Muñoz, Brent J Small, Takahiro Soda, Laura N Torgerson, Clarissa E Sanchez, Jehannine Austin, Eric A Storch, Gabriel Lázaro-Muñoz

Center for Medical Ethics and Health Policy Staff Publications

Psychiatric polygenic risk scores (PRS) have potential utility in psychiatric care and prevention, but there are concerns about their implementation. We surveyed 960 US-based practicing child and adolescent psychiatrists' (CAP) about their experiences, perspectives, and potential uses of psychiatric PRS. While 23% of CAP reported that they had never heard of PRS, 10 % of respondents have had a patient/family bring PRS to them and 4% have generated PRS for patients. Though 25% stated they would request PRS if a patient/caregiver asked, 35% indicated that nothing would prompt them to request PRS. Most respondents (54%) believed psychiatric PRS are currently …

The Development And Initial Validation Of The Promis®+Hf-27 And Promis+Hf-10 Profiles, Faraz S Ahmad, Kathryn L Jackson, Susan E Yount, Nan E Rothrock, Michael A Kallen, Leilani Lacson, Karl Y Bilimoria, Abel N Kho, Raja Kannan Mutharasan, Peter A Mccullough, Jeffrey Bruckel, Savitri Fedson, Stephen E Kimmel, David T Eton, Kathleen L Grady, Clyde W Yancy, David Cella

Center for Medical Ethics and Health Policy Staff Publications

Aims: Heart failure (HF) is a common and morbid condition impacting multiple health domains. We previously reported the development of the PROMIS®-Plus-HF (PROMIS+HF) profile measure, including universal and HF-specific items. To facilitate use, we developed shorter, PROMIS+HF profiles intended for research and clinical use.

Methods and results: Candidate items were selected based on psychometric properties and symptom range coverage. HF clinicians (n = 43) rated item importance and clinical actionability. Based on these results, we developed the PROMIS+HF-27 and PROMIS+HF-10 profiles with summary scores (0-100) for overall, physical, mental, and social health. In a cross-sectional sample (n = 600), we …

T1 Signal Intensity Ratio Of The Pancreas As An Imaging Biomarker For The Staging Of Chronic Pancreatitis, Temel Tirkes, Anil K Dasyam, Zarine K Shah, Evan L Fogel, Santhi Swaroop Vege, Liang Li, Shuang Li, Stephanie T Chang, Carlos A Farinas, Joseph R Grajo, Kareem Mawad, Naoki Takahashi, Sudhakar K Venkatesh, Ashley Wachsman, William E Fisher, Christopher E Forsmark, Phil A Hart, Stephen J Pandol, Walter G Park, Stephen K Van Den Eeden, Yunlong Yang, Mark Topazian, Dana K Andersen, Jose Serrano, Darwin L Conwell, Dhiraj Yadav, Consortium For The Study Of Chronic Pancreatitis, Diabetes, Pancreatic Cancer (Cpdpc)

Center for Medical Ethics and Health Policy Staff Publications

Purpose: Our purpose was to validate the T1 SIR (T1 score) as an imaging biomarker for the staging of CP in a large, multi-institutional, prospective study.

Methods: The prospective study population included 820 participants enrolled in the PROCEED study from nine clinical centers between June 2017 and December 2021. A radiologist at each institution used a standardized method to measure the T1 signal intensity of the pancreas and the reference organs (spleen, paraspinal muscle, liver), which was used to derive respective T1 scores. Participants were stratified according to the seven mechanistic stages of chronic pancreatitis (MSCP 0-6) based on their …

Residence In A Latinx Enclave And End-Induction Minimal Residual Disease Positivity Among Children With Acute Lymphoblastic Leukemia, Joshua P Muñiz, John P Woodhouse, Amy E Hughes, Sandi L Pruitt, Karen R Rabin, Michael E Scheurer, Philip J Lupo, Jeremy M Schraw

Center for Medical Ethics and Health Policy Staff Publications

Racial and ethnic inequities in survival persist for children with acute lymphoblastic leukemia (ALL). In the US, there are strong associations between SES, race/ethnicity, and place of residence. This is evidenced by ethnic enclaves: neighborhoods with high concentrations of ethnic residents, immigrants, and language isolation. The Latinx enclave index (LEI) can be used to investigate how residence in a Latinx enclave is associated with health outcomes. We studied the association between LEI score and minimal residual disease (MRD) in 142 pediatric ALL patients treated at Texas Children's Hospital. LEI score was associated with end-induction MRD positivity (OR per unit increase …

Characteristics Of Graft-Versus-Host Disease (Gvhd) After Post-Transplantation Cyclophosphamide Versus Conventional Gvhd Prophylaxis, Rima M Saliba, Amin M Alousi, Joseph Pidala, Mukta Arora, Stephen R Spellman, Michael T Hemmer, Tao Wang, Camille Abboud, Sairah Ahmed, Joseph H Antin, Amer Beitinjaneh, David Buchbinder, Michael Byrne, Jean-Yves Cahn, Hannah Choe, Rabi Hanna, Peiman Hematti, Rammurti T Kamble, Carrie L Kitko, Mary Laughlin, Lazaros Lekakis, Margaret L Macmillan, Rodrigo Martino, Parinda A Mehta, Taiga Nishihori, Sagar S Patel, Miguel-Angel Perales, Hemalatha G Rangarajan, Olov Ringdén, Joseph Rosenthal, Bipin N Savani, Kirk R Schultz, Sachiko Seo, Takanori Teshima, Marjolein Van Der Poel, Leo F Verdonck, Daniel Weisdorf, Baldeep Wirk, Jean A Yared, Jeffrey Schriber, Richard E Champlin, Stefan O Ciurea

Center for Medical Ethics and Health Policy Staff Publications

Post-transplantation cyclophosphamide (PTCy) has been shown to effectively control graft-versus-host disease (GvHD) in haploidentical (Haplo) transplantations. In this retrospective registry study, we compared GvHD organ distribution, severity, and outcomes in patients with GvHD occurring after Haplo transplantation with PTCy GvHD prophylaxis (Haplo/PTCy) versus HLA-matched unrelated donor transplantation with conventional prophylaxis (MUD/conventional). We evaluated 2 cohorts: patients with grade 2 to 4 acute GvHD (aGvHD) including 264 and 1163 recipients of Haplo and MUD transplants; and patients with any chronic GvHD (cGvHD) including 206 and 1018 recipients of Haplo and MUD transplants, respectively. In comparison with MUD/conventional transplantation ± antithymocyte globulin …

Understanding Covid-19’S Impact On Local Transportation Revenue –A Mid-Crisis View From Experts, Asha Weinstein Agrawal, Serena Alexander, Ashley M. Hooper

Mineta Transportation Institute

When COVID-19 swept into the United States in early 2020, it upended two patterns of behavior critical to transportation funding: how people traveled and where economic activity occurred. This study explored how, one year into the pandemic, experts in California believed that the COVID-19 pandemic was impacting local transportation budgets. We interviewed 34 funding experts who represented local transportation and public works departments, state officials, and municipal finance experts. In these conversations, conducted from December 2020 to March 2021, we asked interviewees how they saw COVID-19 impacting their overall local transportation budgets in the short and long term as well …

Towards A Definitive Symptom Structure Of Obsessive-Compulsive Disorder: A Factor And Network Analysis Of 87 Distinct Symptoms In 1366 Individuals, Matti Cervin, Euripedes C Miguel, Ayşegül Selcen Güler, Ygor A Ferrão, Ayşe Burcu Erdoğdu, Luisa Lazaro, Sebla Gökçe, Daniel A Geller, Yasemin Yulaf, Şaziye Senem Başgül, Özlem Özcan, Koray Karabekiroğlu, Leonardo F Fontenelle, Yankı Yazgan, Eric A Storch, James F Leckman, Maria Conceição Do Rosário, David Mataix-Cols

Center for Medical Ethics and Health Policy Staff Publications

Background: The symptoms of obsessive-compulsive disorder (OCD) are highly heterogeneous and it is unclear what is the optimal way to conceptualize this heterogeneity. This study aimed to establish a comprehensive symptom structure model of OCD across the lifespan using factor and network analytic techniques.

Methods: A large multinational cohort of well-characterized children, adolescents, and adults diagnosed with OCD (N = 1366) participated in the study. All completed the Dimensional Yale-Brown Obsessive-Compulsive Scale, which contains an expanded checklist of 87 distinct OCD symptoms. Exploratory and confirmatory factor analysis were used to outline empirically supported symptom dimensions, and interconnections among the …

Psychiatric Polygenic Risk Scores: Child And Adolescent Psychiatrists’ Knowledge, Attitudes, And Experiences, Stacey Pereira, Katrina A Muñoz, Brent J Small, Takahiro Soda, Laura N Torgerson, Clarissa E Sanchez, Jehannine Austin, Eric A Storch, Gabriel Lázaro-Muñoz

Center for Medical Ethics and Health Policy Staff Publications

Psychiatric polygenic risk scores (PRS) have potential utility in psychiatric care and prevention, but there are concerns about their implementation. We surveyed 960 US-based practicing child and adolescent psychiatrists' (CAP) about their experiences, perspectives, and potential uses of psychiatric PRS. While 23% of CAP reported that they had never heard of PRS, 10 % of respondents have had a patient/family bring PRS to them and 4% have generated PRS for patients. Though 25% stated they would request PRS if a patient/caregiver asked, 35% indicated that nothing would prompt them to request PRS. Most respondents (54%) believed psychiatric PRS are currently …

Are There Transit Deserts In Europe? A Study Focusing On Four European Cases Through Publicly Available Data, Yefu Chen, Junfeng Jiao

Research Collection College of Integrative Studies

Public transit has been proven as an affordable travel method, while the inequitable distribution is a rising concern among practitioners and researchers. A transit desert, based on the demand and supply concept in measuring the mismatch in allocating the level of public transit service, has proved its ability to be applied in cases across countries. According to this concept, this study investigated transit deserts in four cases in Europe. Results indicate that the public transit system in Grand Paris and Madrid are superior due to a smaller population living in areas where public transit cannot meet the demand. Moreover, we …

Exploring The Effects Of Meaningful Tactile Display On Perception And Preference In Automated Vehicles, Kimberly D. Martinez, Gaojian Huang

Mineta Transportation Institute

There is an existing issue in human-machine interaction, such that drivers of semi-autonomous vehicles are still required to take over control of the vehicle during system limitations. A possible solution may lie in tactile displays, which can present status, direction, and position information while avoiding sensory (e.g., visual and auditory) channels overload to reliably help drivers make timely decisions and execute actions to successfully take over. However, limited work has investigated the effects of meaningful tactile signals on takeover performance. This study synthesizes literature investigating the effects of tactile displays on takeover performance in automated vehicles and conducts a human-subject …

Large Eddy Simulations Of Wind Shear From Passing Vehicles Under A Freeway Overpass, Hamid Rahai, Assma Begum

Mineta Transportation Institute

California is moving toward a 100% clean energy future, and expanded wind energy will be a major component of the state’s future energy portfolio. Innovations in wind energy resources will move California closer to achieving its goal. To gain a better understanding of transient pressure and the wind shear generated at the bridge poles from passing vehicles, this study performed large-eddy simulations of a vehicle (also called an Ahmed body) moving under a freeway overpass at a distance of 0.75 w (width) from the bridge poles. Results include transient contours of mean velocity, turbulent kinetic energy, vorticity, and pressure around …

Understanding The Safety And Usability Of Personal Vehicles For Non-Driving Individuals With Disabilities And Their Families/Care Providers, Anil R. Kumar, Hannah Bowman

Mineta Transportation Institute

The connections between shared personal vehicles of individuals with disabilities (IWDs) and their household family members play an important role in the mobility, overall health, and well-being of all involved actors, yet this topic remains mostly overlooked within publicly available research. Families that include a non-driving IWD are more likely to be low-income, and often struggle with the costs of operating a family car but, due to insufficient public transportation options, they own vehicles despite their prohibitive cost. This exploratory study utilized the Systems Engineering Initiative for Patient Safety (SEIPS) model, a framework focused on assessing the interplaying sociotechnical factors …

Event Scale Analysis Of Streamflow Response To Wildfire In Oregon, 2020, Will B. Long, Heejun Chang

Geography Faculty Publications and Presentations

Wildfire increases the magnitude of runoff in catchments, leading to the degradation of ecosystems, risk to infrastructure, and loss of life. The Labor Day Fires of 2020 provided an opportunity to compare multiple large and severe wildfires with the objective of determining potential changes to hydrologic processes in Oregon Cascades watersheds. Geographic information systems (GIS) were implemented to determine the total percentage burned and percentage of high burn severity class of six watersheds on the west slope of the Oregon Cascade Range. In addition, two control watersheds were included to contrast the influence of climatic effects. Spatial arrangements of burned …

Fulcrum, Newsletter Of The Furman University Libraries. Issue 17, Kathie Sloan, Kathy Hamlin

Libraries Institutional Records

Table of Contents

• From the Director
• Tribute to Jenny Colvin
• Welcome New Librarians: Brittany Champion and Alyssa Nance
• Americans and the Holocaust Traveling Exhibition
• Portrait to Honor Sarah Reese '71
• Patricia Sasser Receives Carol June Bradley Award
• Paige Dhyne Faculty Scholar in Northern Ireland
• Special Collections and Archives: Art History Assignments; New Medieval Manuscripts
• Nancy Sloan Retires after 25+ Years at Furman
• Students Help the Libraries Improve Their Inclusive Descriptive Practices
• Two Library Student Assistants Receive Prestigious Furman Fellows Award
• Interested in Publishing Open Access?
• Pilot Program: Library Digital Accessibility Students
• Senior Spotlight: Furman Libraries' Newest Student Worker Alumni
• 2022 …

Content Moderation As Surveillance, Hannah Bloch-Wehba

Faculty Scholarship

Technology platforms are the new governments, and content moderation is the new law, or so goes a common refrain. As platforms increasingly turn toward new, automated mechanisms of enforcing their rules, the apparent power of the private sector seems only to grow. Yet beneath the surface lies a web of complex relationships between public and private authorities that call into question whether platforms truly possess such unilateral power. Law enforcement and police are exerting influence over platform content rules, giving governments a louder voice in supposedly “private” decisions. At the same time, law enforcement avails itself of the affordances of …

An Electrophysiological Examination Of Attentional Biases To Emotional Faces In Depression And Social Anxiety, Nathan M. Hager

Psychology Theses & Dissertations

Cognitive theories have proposed that major depressive disorder (MDD) and social anxiety disorder (SAD) involve attentional biases toward and away from specific environmental stimuli. Research has often examined these biases in response to emotional facial expressions, but evidence of attentional biases is mixed. An event-related potential called the N2pc offers advantages over other measures of attentional bias and may clarify conflicting findings. Studies on the N2pc and social anxiety have found consistent results, but there is little work examining depression. Previous N2pc studies are limited by the types of emotional faces they use and by comparing attention for emotional faces …

Reducing Prejudice Through Law: Evidence From Experimental Psychology, Sara Emily Burke, Roseanna Sommers

Articles

Can antidiscrimination law effect changes in public attitudes toward minority groups? Could learning, for instance, that employment discrimination against people with clinical depression is legally prohibited cause members of the public to be more accepting toward people with mental health conditions? In this Article, we report the results of a series of experiments that test the effect of inducing the belief that discrimination against a given group is legal (versus illegal) on interpersonal attitudes toward members of that group. We find that learning that discrimination is unlawful does not simply lead people to believe that an employer is more likely …

Socioeconomic And Comorbid Factors Affecting Mortality And Length Of Stay In Covid-19 Patients, Adam Delora, Ashlynn Mills, David Jacobson, Brendon Cornett, William F Peacock, Anita Datta, Shane P Jenks

Faculty, Staff and Students Publications

Background The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic exposed and exacerbated health disparities between socioeconomic groups. Our purpose was to determine if age, sex, race, insurance, and comorbidities predicted patients' length of stay (LOS) in the hospital and in-hospital mortality in patients diagnosed with coronavirus disease 2019 (COVID-19) during the early pandemic. Methods Utilizing retrospective, secondarily sourced electronic health record (EHR) data for patients who tested positive for COVID-19 from HCA Healthcare facilities, predictors of LOS and in-hospital mortality were assessed using regression. LOS and in-hospital mortality were assessed using logistic regression and negative binomial regression, respectively. All …

Men's Rights, Gun Ownership, Racism, And The Assault On Women's Reproductive Health Rights: Hidden Connections, Walter S. Dekeseredy

Dignity: A Journal of Analysis of Exploitation and Violence

In this current era characterized by much fear of, and anxiety about, the political influence and actions of the U.S. alternative right (alt-right), only a small number of men’s rights organizations receive attention from the media, the Democratic Party, or a large cadre of progressives. This article demonstrates that ignoring all-male anti-feminist organizations is a flawed strategy for challenging the recent rise of the alt-right because these misogynistic groups are heavily involved in the gun rights movement, major contributors to racist practices and discourses, and active participants in efforts to criminalize and curtail women’s access to abortion. Another, but equally …

Religious Hegemony And "Muslim" Horror Movies, Shaheed N. Mohammed

Journal of Religion & Film

The present paper examines horror films originating in Muslim contexts and available on U.S. streaming services. Using Gramsci's concept of hegemony, the paper examines how such films negotiate and articulate with the dominant Hollywood mainstream horror genre with particular attention to the hegemonic power of the mainstream with its Christian iconography and assumptions.

An Examination Of Peer Group Influence And Gender As Correlates Of Library And Information Science Students’ Attitude Towards Examination Malpractice: Implication For The Development Of Students, Emmanuel Chidiadi Onwubiko

Library Philosophy and Practice (e-journal)

Examination malpractice has become a global cankerworm that has eaten so deep into our educational system and posing a serious threat to total development of students in our educational system. In search of solution to this anti-educational behavior, experts have attributed it to many factors including peer influence on the assumption that birds of a feather flock together and on the axiom; ‘show me your friends and I will tell you who you are’. This study therefore examined the peer group influence and gender as correlates of Library and Information Science students’ attitude towards examination malpractice and it implication for …

The Effects Of Cyp1a2 And Adora2a Genotypes Association With Acute Caffeine Intake On Physiological Effects And Performance: A Systematic Review, Rabia Rümeysa Kocatürk, İlke Karagöz, Ebru Yanik, Öznur Özge Özcan, Türker Tekin Ergüzel, Mesut Karahan, Nevzat Tarhan

Baltic Journal of Health and Physical Activity

Introduction: This systematic review aims to examine the effects of the CYP1A2 −163C>A and ADORA2A 1976T>C polymorphism on physiological effects and performance relative to caffeine consumption. Material and Methods: In this study, electronic databases including PubMed, Web of Science Core Collection, Korean Journal Database, Russian Science Citation Index, SciELO Citation Index, Scopus, ScienceDirect, ProQuest Dissertations & Thesis Global and EBSCO were searched. Results: The results highlight that individuals with the TT or CT/CC genotype can have differences in caffeine consumption, and C carriers may have increases in the maximum oxygen uptake (VO₂max). The AA or AC/CC …

Investigating Commercial Urban Corridors - A Pilot Study In Beirut Lebanon, Nour El Baba, Ibtihal Y. El-Bastawissi, Ayman Afify, Hiba Mohsen

Architecture and Planning Journal (APJ)

Urban environments are multifaceted, varied, dynamic, complex, and evolving as are the underlying features for human health and wellbeing (Bai, Nath, Capon, Hasan & Jaron, 2020). Healthy and resilient cities can be entry points and platforms for change, adaptation and innovation to achieve optimal health for urban communities and the environment (Regional Framework for Urban Health in the Western Pacific 2016–2020: Healthy and Resilient Cities, 2016). Planners considered urban corridors, which are connection and access between urban districts, as major elements in shaping the city image and forming its identity and investigating them are vital for enhancing healthy and resilient …

Exploring The Attributes Of Open Public Spaces In The Developing Cities, Aya Chehab

Architecture and Planning Journal (APJ)

Open Public Spaces, according to Commission for Architecture and the Built Environment (CABE), are vital elements of urban fabrics that animate communities in cities. These significant spaces not only provide the residents with different facilities, but also promote social, economic, environmental and health opportunities. Successful open public spaces meet the needs of people of various social classes, ethnicities, and different backgrounds in general. Despite its importance within the city, the lack of appropriate design and planning strategies in developing cities have resulted in a degradation of the urban environment and subsequently the quality of urban life. The problem needs to …

Developing An Agent-Based Model Of Pedestrian Wayfinding To Conduct The Best Touristic Path In Historic Districts, Saada Hassan Khaled, Eslam M. Elsamahy, Mary Felix

Architecture and Planning Journal (APJ)

A historic district is a historic and cultural conservation area that reflects traditional aspects from the past. A sense of memorable pathway allows pedestrian to experience the city happily and attract touristic activity in urban historic districts. The characteristics of touristic districts which facilitate pedestrian movement help in determining the optimum track. The aim of the research is to create an agent-based model (ABM) to simulate the activity of pedestrians in historic districts in order to way find the best touristic paths. Using Space-Syntax, a simulation of the interaction of tourists with the attraction points in old districts pathway will …