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Pharmacological Reversal Of Cognitive Bias In The Chick Anxiety-Depression Continuum Model, Kristen Anne Hymel

Electronic Theses and Dissertations

Cognitive bias is a phenomenon that presents in clinical populations where anxious individuals tend to adopt a more pessimistic interpretation of ambiguous aversive stimuli and depressed individuals not only tend to adopt a more pessimistic interpretation of ambiguous aversive stimuli, but also a less optimistic interpretation of ambiguous appetitive stimuli. Such biases have also been pharmacologically reversed in clinical trials. To measure cognitive bias in the chick anxiety-depression continuum model, chicks exposed to an isolation stressor of 5 min to induce an anxiety-like or 60 min to induce a depressive-like state were then tested in a straight alley maze to …