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Induction And Expression Of Cocaine-Induced Behavioral Sensitization: Modulation By A Partial D₂-Like Agonist, Janet Marie Sibole
Induction And Expression Of Cocaine-Induced Behavioral Sensitization: Modulation By A Partial D₂-Like Agonist, Janet Marie Sibole
Theses Digitization Project
The purpose of this study was to investigate whether a partial D₂-like dopamine agonist (i.e. terguride) would block the induction or expression of cocaine-induced behavioral sensitization in pre-weanling rats. The ability of terguride to induce behavioral sensitization was also examined, as partial D₂-like agonists have agonistic actions in cases of low dopaminergic tone.