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Social and Behavioral Sciences Commons™
Open Access. Powered by Scholars. Published by Universities.®
- Keyword
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- Dopamine -- Receptors -- Effect of drugs on (2)
- Rats -- Physiology (2)
- Animal locomotion (1)
- Central nervous system -- Effects of drugs on (1)
- Cocaine -- Physiological aspects (1)
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- Cocaine -- Physiological effect (1)
- Dopamine -- Agonists -- Theraputic use -- Testing (1)
- Dopaminergic mechanisms (1)
- Drug abuse -- Animal models (1)
- Drug abuse -- Susceptibility (1)
- Ecstasy (Drug) (1)
- Neural circuitry (1)
- Neurotoxic agents (1)
- Serotoninergic mechanisms (1)
- Superior colliculus -- Physiology (1)
- Thalamus -- Physiology (1)
Articles 1 - 3 of 3
Full-Text Articles in Social and Behavioral Sciences
Long-Term Effects Of 3,4- Methylenedioxymethamphetamine (Mdma) On Serotonergic And Dopaminergic Functioning, Jodi Lynn Kohutek
Long-Term Effects Of 3,4- Methylenedioxymethamphetamine (Mdma) On Serotonergic And Dopaminergic Functioning, Jodi Lynn Kohutek
Theses Digitization Project
Methylenedioxymethamphetamine (MDMA) popularly known as "Ecstasy" continues to gain popularity as a recreational drug that has been shown to increase serotonin and dopamine levels. The present study has demonstrated that repeated exposure to MDMA produces long-term damage to serotonergic and dopaminergic neurons in various regions of the rat brain.
The Effects Of Lesions To The Superior Colliculus And Ventromedial Thalamus On [Kappa]-Opioid-Mediated Locomotor Activity In The Preweanling Rat, Arturo Rubin Zavala
The Effects Of Lesions To The Superior Colliculus And Ventromedial Thalamus On [Kappa]-Opioid-Mediated Locomotor Activity In The Preweanling Rat, Arturo Rubin Zavala
Theses Digitization Project
The purpose of this thesis was to determine the neuronal circuitry mediating U50,488-induced locomotion in preweanling rats. To this end, preweanling rats received bilateral electrolytic lesions of the ventromedial thalamus or superior colliculus and, two days later, the same rats received a challenge injection of U50,488. It was predicted that bilateral lesions of the ventromedial thalamus or superior colliculus would attenuate the U50,488-induced locomotor activity of 18-day-old rats.
Induction And Expression Of Cocaine-Induced Behavioral Sensitization: Modulation By A Partial D₂-Like Agonist, Janet Marie Sibole
Induction And Expression Of Cocaine-Induced Behavioral Sensitization: Modulation By A Partial D₂-Like Agonist, Janet Marie Sibole
Theses Digitization Project
The purpose of this study was to investigate whether a partial D₂-like dopamine agonist (i.e. terguride) would block the induction or expression of cocaine-induced behavioral sensitization in pre-weanling rats. The ability of terguride to induce behavioral sensitization was also examined, as partial D₂-like agonists have agonistic actions in cases of low dopaminergic tone.