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Faculty of Science, Medicine and Health - Papers: part A

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The Chronostratigraphy Of The Haua Fteah Cave (Cyrenaica, Northeast Libya) - Optical Dating Of Early Human Occupation During Marine Isotope Stages 4, 5 And 6, Zenobia Jacobs, Bo Li, Lucy Farr, Evan Hill, C Hunt, Sacha C. Jones, Ryan J. Rabett, Tim Reynolds, Richard G. Roberts, David Simpson, Graeme Barker Jan 2017

The Chronostratigraphy Of The Haua Fteah Cave (Cyrenaica, Northeast Libya) - Optical Dating Of Early Human Occupation During Marine Isotope Stages 4, 5 And 6, Zenobia Jacobs, Bo Li, Lucy Farr, Evan Hill, C Hunt, Sacha C. Jones, Ryan J. Rabett, Tim Reynolds, Richard G. Roberts, David Simpson, Graeme Barker

Faculty of Science, Medicine and Health - Papers: part A

The paper presents the results of optical dating of potassium-rich feldspar grains obtained from the Haua Fteah cave in Cyrenaica, northeast Libya, focussing on the chronology of the Deep Sounding excavated by Charles McBurney in the 1950s and re-excavated recently. Samples were also collected from a 1.25 m-deep trench (Trench S) excavated during the present project below the basal level of the Deep Sounding. Optically stimulated luminescence (OSL) data sets for multi-grain, single aliquots of quartz for samples from the Middle Trench were previously published. Re-analyses of these OSL data confirm significant variation in the dose saturation levels of the …


6-Hydroxy-5,6-Seco-Stemocurtisine: A Novel Seco-Stemocurtisine-Type Alkaloid, Pitchaya Mungkornasawakul, Stephen G. Pyne, Anthony C. Willis, Araya Jatisatienr, Duang Phuthsuk, Wilford Lie Jan 2013

6-Hydroxy-5,6-Seco-Stemocurtisine: A Novel Seco-Stemocurtisine-Type Alkaloid, Pitchaya Mungkornasawakul, Stephen G. Pyne, Anthony C. Willis, Araya Jatisatienr, Duang Phuthsuk, Wilford Lie

Faculty of Science, Medicine and Health - Papers: part A

A novel seco-stemocurtisine-type alkaloid, 6-hydroxy-5,6-seco-stemocurtisine was isolated from the aerial parts of Stemona curtisii (Stemonaceae) collected from Trang Province in Thailand. The unprecedented 5,6-seco-pyrido[1,2-a] azepine structure was elucidated by 2D NMR analysis and a single crystal X-ray crystallographic analysis. (C) 2013 Phytochemical Society of Europe.


Effect Of 6 Weeks' Consumption Of Β-Glucan-Rich Oat Products On Cholesterol Levels In Mildly Hypercholesterolaemic Overweight Adults, Karen E. Charlton, Linda C. Tapsell, Marijka J. Batterham, Jane O'Shea, Rebecca Thorne, Eleanor Beck, Susan M. Tosh Jan 2012

Effect Of 6 Weeks' Consumption Of Β-Glucan-Rich Oat Products On Cholesterol Levels In Mildly Hypercholesterolaemic Overweight Adults, Karen E. Charlton, Linda C. Tapsell, Marijka J. Batterham, Jane O'Shea, Rebecca Thorne, Eleanor Beck, Susan M. Tosh

Faculty of Science, Medicine and Health - Papers: part A

Several regulatory bodies have approved a health claim on the cholesterol-lowering effects of oat β-glucan at levels of 3·0 g/d. The present study aimed to test whether 1·5 g/d β-glucan provided as ready-to-eat oat flakes was as effective in lowering cholesterol as 3·0 g/d from oats porridge. A 6-week randomised controlled trial was conducted in eighty-seven mildly hypercholesterolaemic ( ≥ 5 mmol/l and < 7·5 mmol/l) men and women assigned to one of three diet arms (25 % energy (E%) protein; 45 E% carbohydrate; 30 E% fat, at energy requirements for weight maintenance): (1) minimal β-glucan (control); (2) low-dose oat β-glucan (1·5 g β-glucan; oats low – OL) or (3) higher dose oat β-glucan (3·0 g β-glucan; oats high – OH). Changes in total cholesterol and LDL-cholesterol (LDL-C) from baseline were assessed using a linear mixed model and repeated-measures ANOVA, adjusted for weight change. Total cholesterol reduced significantly in all groups ( − 7·8 (sd 13·8) %, − 7·2 (sd 12·4) % and − 5·5 (sd 9·3) % in the OH, OL and control groups), as did LDL-C ( − 8·4 (sd 18·5) %, − 8·5 (sd 18·5) % and − 5·5 (sd 12·4) % in the OH, OL and control groups), but between-group differences were not significant. In responders only (n 60), β-glucan groups had higher reductions in LDL-C ( − 18·3 (sd 11·1) % and − 18·1 (sd 9·2) % in the OH and OL groups) compared with controls ( − 11·7 (sd 7·9) %; P = 0·044). Intakes of oat β-glucan were as effective at doses of 1·5 g/d compared with 3 g/d when provided in different food formats that delivered similar amounts of soluble β-glucan.


Dietary Docosahexaenoic Acid (22:6) Incorporates Into Cardiolipin At The Expense Of Linoleic Acid (18:2): Analysis And Potential Implications, Colin Cortie, Paul L. Else Jan 2012

Dietary Docosahexaenoic Acid (22:6) Incorporates Into Cardiolipin At The Expense Of Linoleic Acid (18:2): Analysis And Potential Implications, Colin Cortie, Paul L. Else

Faculty of Science, Medicine and Health - Papers: part A

Cardiolipin is a signature phospholipid of major functional significance in mitochondria. In heart mitochondria the fatty acid composition of cardiolipin is commonly viewed as highly regulated due to its high levels of linoleic acid (18:2n − 6) and the dominant presence of a 4×18:2 molecular species. However, analysis of data from a comprehensive compilation of studies reporting changes in fatty acid composition of cardiolipin in heart and liver mitochondria in response to dietary fat shows that, in heart the accrual of 18:2 into cardiolipin conforms strongly to its dietary availability at up to 20% of total dietary fatty acid and …


Fire Retardancy And Morphology Of Nylon 6-Clay Nanocomposite Compositions, Kadhirava Shanmuganathan, Sandeep Razdan, Nicholas Dembsey, Qinguo Fan, Yong K. Kim, Paul D. Calvert, Steven B. Warner, Prabir Patra Jan 2005

Fire Retardancy And Morphology Of Nylon 6-Clay Nanocomposite Compositions, Kadhirava Shanmuganathan, Sandeep Razdan, Nicholas Dembsey, Qinguo Fan, Yong K. Kim, Paul D. Calvert, Steven B. Warner, Prabir Patra

Faculty of Science, Medicine and Health - Papers: part A

We investigated the effect of organically modified clay on the thermal and flammability behavior of nylon 6 nanocomposites. We also used zinc borate along with layered silicate with an aim of achieving synergistic effect in flame retardancy. It is found that addition of 10 wt% clay reduced the onset decomposition (5% wt loss) temperature of nylon 6 by 20°C, while addition of 5 wt% zinc borate and 5 wt% clay in combination reduced it by around 10°C. Differential thermogravimetric analysis indicated that the peak decomposition temperature was not affected by the addition of clay, but the rate of weight loss …


Systemic Levels Of Interleukin-6 And Matrix Metalloproteinase-9 In Patients With Multiple Myeloma May Be Useful As Prognostic Indexes Of Bone Disease, Aikaterini Sfiridaki, Spyridon Miyakis, George Tsirakis, Athanasios Alegakis, Andreas M. Passam, Ermioni Kandidaki, Andrerw N. Margioris, Michael Alexandrakis Jan 2005

Systemic Levels Of Interleukin-6 And Matrix Metalloproteinase-9 In Patients With Multiple Myeloma May Be Useful As Prognostic Indexes Of Bone Disease, Aikaterini Sfiridaki, Spyridon Miyakis, George Tsirakis, Athanasios Alegakis, Andreas M. Passam, Ermioni Kandidaki, Andrerw N. Margioris, Michael Alexandrakis

Faculty of Science, Medicine and Health - Papers: part A

Multiple myeloma is characterized by accelerated production of the proteolytic enzyme matrix metalloproteinase (MMP)-9. We hypothesized that myeloma- produced MMP-9 may influence the rate of bone turnover in a paracrine manner. Thus, we examined the correlations of MMP-9 levels, disease severity, and bone turnover rate as evaluated by markers of bone formation and resorption. Thirty-seven newly diagnosed multiple myeloma patients (nine of Durie-Salmon stage I, 12 of stage II and 16 of stage III) and 12 age-matched controls were studied. Serum MMP-9 levels were significantly higher at stage II compared to stage I (188.78"91.27 vs. 59.25"33.09 ng/mL, p-0.004). Additionally, free …


Intakes And Food Sources Of Omega-6 And Omega-3 Pufa, Barbara J. Meyer, Peter Howe, Janine Lewis, Greg Milligan, Neil Mann, Andrew Sinclair Jan 2002

Intakes And Food Sources Of Omega-6 And Omega-3 Pufa, Barbara J. Meyer, Peter Howe, Janine Lewis, Greg Milligan, Neil Mann, Andrew Sinclair

Faculty of Science, Medicine and Health - Papers: part A

Abstract presented at The 2nd Omega Workshop, 30 September 2002, Adelaide, Australia.


Dietary N-3 And N-6 Fatty Acids Alter Avian Metabolism: Molecular-Species Compostiton Of Breast-Muscle Phospholipids, Ronald Newman, Wayne Bryden, Eva Fleck, John R. Ashes, Leonard Storlien, Jeffery A. Downing Jan 2002

Dietary N-3 And N-6 Fatty Acids Alter Avian Metabolism: Molecular-Species Compostiton Of Breast-Muscle Phospholipids, Ronald Newman, Wayne Bryden, Eva Fleck, John R. Ashes, Leonard Storlien, Jeffery A. Downing

Faculty of Science, Medicine and Health - Papers: part A

The effects of diets high in n-3 polyunsaturated fatty acids (PUFA; provided by fish oil), n-6 PUFA (sunflower oil) or in more-saturated fatty acids (tallow) on the distribution of subclasses of choline phospholipids (PC) and ethanolamine phospholipids (PE) from the breast muscle of broiler chickens were examined. Supplementation with the different fatty acids had no effect on the distribution of phospholipid subclasses. Feeding sunflower oil or tallow gave a molecular-species profile similar in both fatty acid subtype and proportion. In the diacyl PC phospholipids, 16: 0–18: 1n-9 and 16: 0–18: 2n-6 accounted for approximately …


Dietary N-3 And N-6 Fatty Acids Alter Avian Metabolism: Metabolism And Abdominal Fat Deposition, Ronald Newman, Wayne Bryden, Eva Fleck, John R. Ashes, William A. Buttemer, Leonard Storlien, Jeffery Downing Jan 2002

Dietary N-3 And N-6 Fatty Acids Alter Avian Metabolism: Metabolism And Abdominal Fat Deposition, Ronald Newman, Wayne Bryden, Eva Fleck, John R. Ashes, William A. Buttemer, Leonard Storlien, Jeffery Downing

Faculty of Science, Medicine and Health - Papers: part A

The effects of dietary saturated fatty acids and polyunsaturated fatty acids (PUFA) of the n-3 and n-6 series on weight gain, body composition and substrate oxidation were investigated in broiler chickens. At 3 weeks of age three groups of chickens (n 30; ten birds per group) were fed the fat-enriched experimental diets for 5 weeks. These diets were isonitrogenous, isoenergetic and contained 208 g protein/kg and 80 g edible tallow, fish oil or sunflower oil/kg; the dietary fatty acid profiles were thus dominated by saturated fatty acids, n-3 PUFA or n-6 PUFA respectively. Resting RQ …


Mesospheric Temperatures From Observations Of The Hydroxyl (6-2) Emission Above Davis, Antarctica: A Comparison Of Rotational And Doppler Measurements, J L. Innis, Frances Phillips, G B. Burns, P A. Greet, W J R French, P L. Dyson Jan 2001

Mesospheric Temperatures From Observations Of The Hydroxyl (6-2) Emission Above Davis, Antarctica: A Comparison Of Rotational And Doppler Measurements, J L. Innis, Frances Phillips, G B. Burns, P A. Greet, W J R French, P L. Dyson

Faculty of Science, Medicine and Health - Papers: part A

We present observations of the hydroxyl (6–2) airglow lines from ~ 87 km altitude obtained at Davis station, Antarctica, in the austral winter of 1999. Nine nights of observations were made of the P-branch near λ840 nm with a Czerny-Turner scanning spectrometer (CTS); at the same time, high-resolution Fabry-Perot Spectrometer (FPS) spectra were collected of the Q1(1) doublet at λ834 nm. Rotational temperatures were determined from the CTS observations, while Doppler temperatures were derived from the line-widths of the FPS Q1(1) spectra. Absolute temperatures determined by these methods are uncertain by ~ 2 and ~ 20 …