Social and Behavioral Sciences Commons^™

Cross-Sectional Study Of Area-Level Disadvantage And Glycaemic-Related Risk In Community Health Service Users In The Southern.Iml Research (Simlr) Cohort, Roger Cross, Andrew D. Bonney, Darren J. Mayne, Kathryn M. Weston

Faculty of Science, Medicine and Health - Papers: part A

Objectives. The aim of the present study was to determine the association between area-level socioeconomic disadvantage and glycaemic-related risk in health service users in the Illawarra-Shoalhaven region of New South Wales, Australia. Methods. HbA1c values recorded between 2010 and 2012 for non-pregnant individuals aged 18 years were extracted from the Southern.IML Research (SIMLR) database. Individuals were assigned quintiles of the Socioeconomic Indices for Australia (SEIFA) Index of Relative Socioeconomic Disadvantage (IRSD) according to their Statistical Area 1 of residence. Glycaemic risk categories were defined as HbA1c 5.0-5.99% (lowest risk), 6.0-7.49% (intermediate risk) and 7.5% (highest risk). Logistic regression models were …

A Mediterranean-Style Dietary Intervention Supplemented With Fish Oil Improves Diet Quality And Mental Health In People With Depression: A Randomized Controlled Trial (Helfimed), Natalie Parletta, Dorota M. Zarnowiecki, Jihyun Cho, Amy Wilson, Svetlana Bogomolova, Anthony Villani, Catherine Itsiopoulos, Theo Niyonsenga, Sarah Blunden, Barbara J. Meyer, Leonie Segal, Bernhard Baune, Kerin O'Dea

Faculty of Science, Medicine and Health - Papers: part A

Objectives: We investigated whether a Mediterranean-style diet (MedDiet) supplemented with fish oil can improve mental health in adults suffering depression. Methods: Adults with self-reported depression were randomized to receive fortnightly food hampers and MedDiet cooking workshops for 3 months and fish oil supplements for 6 months, or attend social groups fortnightly for 3 months. Assessments at baseline, 3 and 6 months included mental health, quality of life (QoL) and dietary questionnaires, and blood samples for erythrocyte fatty acid analysis. Results: n = 152 eligible adults aged 18-65 were recruited (n = 95 completed 3-month and n = 85 completed 6-month …

Experiences Of Registered Nurses Transitioning From Employment In Acute Care To Primary Health Care - Quantitative Findings From A Mixed-Methods Study, Christine Ashley, Elizabeth J. Halcomb, Angela M. Brown, Kathleen Peters

Faculty of Science, Medicine and Health - Papers: part A

Aims and objectives: To describe the experiences of registered nurses who transition from acute to primary health care (PHC) employment.

Background: Internationally the provision of health care in PHC settings is increasing. Nurses are moving from acute care employment to meet the growing demand for a PHC workforce. However, little is known about the transition experiences of these nurses.

Design: A sequential mixed-methods study comprising a survey, and semi-structured interviews. This study reports on survey findings relating to the transition experience.

Methods: Convenience and snowballing techniques were used to recruit 111 registered nurses who had transitioned …

Acetylcholinesterase Inhibitory Activity Of Chemical Constituents Isolated From Miliusa Thorelii, Thanika Promchai, Tongchai Saesong, Kornkanok Ingkaninan, Surat Laphookhieo, Stephen G. Pyne, Thunwadee Ritthiwigrom

Faculty of Science, Medicine and Health - Papers: part A

Two new dihydrooxoprotoberberine alkaloids; miliusathorines A (1) and B (2), a new natural flavone, miliusathorone (3), together with twenty-two known compounds (4-25) were isolated from the combined stem and root extract and the leaf extract of Miliusa thorelii. The structures of all isolated compounds were elucidated by spectroscopic methods and mass spectrometry. All compounds were evaluated for their acetylcholinesterase activities. Miliusathorine A (1) and norushisunine had the best AChE inhibitory activities, however these were weak inhibitors when compared to the standard galantamine.

Measuring The Outcomes Of Nursing Practice: A Delphi Study, Jenny Sim, Patrick A. Crookes, Kenneth D. Walsh, Elizabeth J. Halcomb

Faculty of Science, Medicine and Health - Papers: part A

Aims and objective: To develop nursing-sensitive patient indicators to measure the outcomes of nursing practice.

Background: Nurses play an important role in the healthcare system, yet there is no consensus on how the impact of nursing work should be evaluated. Limited research has previously examined the views of clinical nurses on the important concepts for measuring nursing practice.

Design: A four-round modified Delphi survey sought opinions from patients and nurses about the relevant concepts and their relative priority as indicators of quality nursing practice.

Method: Round 1 comprised semi-structured interviews with patients and nurses to identify …

Resolution And Identification Of Scalemic Caged Xanthones From The Leaf Extract Of Garcinia Propinqua Having Potent Cytotoxicities Against Colon Cancer Cells, Teerayut Sriyatep, Cholpisut Tantapakul, Raymond J. Andersen, Brian O. Patrick, Stephen G. Pyne, Chatchai Muanprasat, Sawinee Seemakhan, Suparerk Borwornpinyo, Surat Laphookhieo

Faculty of Science, Medicine and Health - Papers: part A

A new scalemic 8,8a-dihydro caged xanthone (1) was isolated from the leaf extract of Garcinia propinqua. Five other known natural products, the three caged xanthones (2, 5 and 6) and the two neocaged xanthones, (3 and 4) were also isolated as scalemic mixtures. Their structures were characterized by spectroscopic methods. The enantiomeric ratios (er) of compounds 1-6 ranged from 1:0.7 to 1:0.9. These compounds were also resolved by semipreparative chiral HPLC. The absolute configurations of (+)-2 and (+)-3 were determined by single-crystal X-ray diffraction analysis using Cu Kα radiation while the absolute configurations of the other compounds were determined by …

Active Migration Is Associated With Specific And Consistent Changes To Gut Microbiota In Calidris Shorebirds, Alice Risely, David Waite, Beata Ujvari, Bethany J. Hoye, Marcel Klaassen

Faculty of Science, Medicine and Health - Papers: part A

Gut microbes are increasingly recognised for their role in regulating an animal's metabolism and immunity. However, identifying repeatable associations between host physiological processes and their gut microbiota has proved challenging, in part because microbial communities often respond stochastically to host physiological stress (e.g. fasting, forced exercise or infection). Migratory birds provide a valuable system in which to test host-microbe interactions under physiological extremes because these hosts are adapted to predictable metabolic and immunological challenges as they undergo seasonal migrations, including temporary gut atrophy during long-distance flights. These physiological challenges may either temporarily disrupt gut microbial ecosystems, or, alternatively, promote predictable …

Impact Of Climate Change And Human Activity On Soil Landscapes Over The Past 12,300 Years, Leo Rothacker, Anthony Dosseto, Alexander Francke, Allan Chivas, Nathalie Vigier, Anna M. Kotarba-Morley, Davide Menozzi

Faculty of Science, Medicine and Health - Papers: part A

Soils are key to ecosystems and human societies, and their critical importance requires a better understanding of how they evolve through time. However, identifying the role of natural climate change versus human activity (e.g. agriculture) on soil evolution is difficult. Here we show that for most of the past 12,300 years soil erosion and development were impacted differently by natural climate variability, as recorded by sediments deposited in Lake Dojran (Macedonia/Greece): short-lived ( < 1,000 years) climatic shifts had no effect on soil development but impacted soil erosion. This decoupling disappeared between 3,500 and 3,100 years ago, when the sedimentary record suggests an unprecedented erosion event associated with the development of agriculture in the region. Our results show unambiguously how differently soils evolved under natural climate variability (between 12,300 and 3,500 years ago) and later in response to intensifying human impact. The transition from natural to anthropogenic landscape started just before, or at, the onset of the Greek 'Dark Ages' (~3,200 cal yr BP). This could represent the earliest recorded sign of a negative feedback between civilization and environmental impact, where the development of agriculture impacted soil resources, which in turn resulted in a slowdown of civilization expansion.

What Is All This Fuss About Tus? Comparison Of Recent Findings From Biophysical And Biochemical Experiments, Bojk A. Berghuis, Vlad Raducanu, Mohamed M. Elshenawy, Slobodan Jergic, Martin Depken, Nicholas E. Dixon, Samir M. Hamdan, Nynke H. Dekker

Faculty of Science, Medicine and Health - Papers: part A

Synchronizing the convergence of the two-oppositely moving DNA replication machineries at specific termination sites is a tightly coordinated process in bacteria. In Escherichia coli, a "replication fork trap"-found within a chromosomal region where forks are allowed to enter but not leave-is set by the protein-DNA roadblock Tus-Ter. The exact sequence of events by which Tus-Ter blocks replisomes approaching from one direction but not the other has been the subject of controversy for many decades. Specific protein-protein interactions between the nonpermissive face of Tus and the approaching helicase were challenged by biochemical and structural studies. These studies …

Plasma Cortisol And Oxytocin Levels Predict Help-Seeking Intentions For Depressive Symptoms, Susan J. Thomas, Theresa A. Larkin

Faculty of Science, Medicine and Health - Papers: part A

Background: Depressed individuals often refuse or withdraw from help, a phenomenon termed help-negation, which is a risk factor for poor outcomes. Most previous research has investigated psychosocial factors including stigma as causes of low help-seeking intentions for depression, however these do not adequately explain the problem. We hypothesised that because help-negation worsens with symptom severity, it might be linked to important biological changes associated with depression itself. We investigated the relative contributions of cortisol, a stress hormone linked to depression, and oxytocin, a hormone which mediates social behaviours, alongside psychosocial factors, to help-seeking intentions among depressed and non-depressed individuals. Methods: …

Exploring Approaches To Dietetic Assessment Of A Common Task Across Different Universities Through Assessment Moderation, Claire Palermo, E Volders, S Gibson, Meredith A. Kennedy, A Wray, J Thomas, Mary Hannan-Jones, Danielle Gallegos, Eleanor J. Beck

Faculty of Science, Medicine and Health - Papers: part A

Background: Assessment presents one of the greatest challenges to evaluating health professional trainee performance, as a result of the subjectivity of judgements and variability in assessor standards. The present study aimed to test a moderation procedure for assessment across four independent universities and explore approaches to assessment and the factors that influence assessment decisions. Methods: Assessment tasks designed independently by each of the four universities to assess student readiness for placement were chosen for the present study. Each university provided four student performance recordings for moderation. Eight different academic assessors viewed the student performances and assessed them using the corresponding …

Validation And Comparison Of A Model Of The Effect Of Sea-Level Rise On Coastal Wetlands, Laura Mogensen, Kerrylee Rogers

Faculty of Science, Medicine and Health - Papers: part A

Models are used to project coastal wetland distribution under future sea-level rise scenarios to assist decision-making. Model validation and comparison was used to investigate error and uncertainty in the Sea Level Affecting Marshes Model, a readily available model with minimal validation, particularly for wetlands beyond North America. Accurate parameterisation is required to improve the performance of the model, and indeed any spatial model. Consideration of tidal attenuation further enhances model performance, particularly for coastal wetlands located within estuaries along wave-dominated coastlines. The model does not simulate vegetation changes that are known to occur, particularly when sedimentation exceeds rates of sea-level …

National Sediment Compartment Framework For Australian Coastal Management, Bruce G. Thom, I G Eliot, M Eliot, Nicholas Harvey, David Rissik, Chris Sharples, Andrew D. Short, Colin D. Woodroffe

Faculty of Science, Medicine and Health - Papers: part A

The concept of coastal sediment compartments was first used in the 1960s in the United States. It has since been recognised as appropriate for defining sections of the Australian coast, but had not been uniformly adopted around the nation in the way that has underpinned management, as in other countries. In 2012, the Australian Government supported a project to better understand coastal sediment dynamics using the sediment compartment approach as a framework within which to consider future shoreline behaviour and the impacts of climate change, including rising sea level, changing wave climates and sediment budgets. This paper outlines the sediment …

Common Products, Like Perfume, Paint And Printer Ink, Are Polluting The Atmosphere, Jenny A. Fisher, Kathryn M. Emmerson

Faculty of Science, Medicine and Health - Papers: part A

Picture the causes of air pollution in a major city and you are likely to visualise pollutants spewing out of cars, trucks and buses. For some types of air pollutants, however, transportation is only half as important as the chemicals in everyday consumer products like cleaning agents, printer ink, and fragrances, according to a study published today in Science.

Finding A Space For Women: The British Medical Association And Women Doctors In Australia, 1880-1939, Louella R. Mccarthy

Faculty of Science, Medicine and Health - Papers: part A

This paper examines the experiences of women in one professional organisation - the British Medical Association in Australia - during a significant period in the development of such bodies. In doing so it offers an opportunity to consider the relationship between professional societies and the construction of a gendered profession. For the medical profession in particular the time-frame of this study, from the 1880s to the 1930s, has been regarded by scholars as especially important. In this period various features of medical professionalism came to prominence: the status and authority of doctors, the processes of formally registering medical credentials, and …

Upper Torso Pain And Musculoskeletal Structure And Function In Women With And Without Large Breasts: A Cross Sectional Study, Deirdre Mcghee, Karly Coltman, Diane L. Riddiford-Harland, Julie R. Steele

Faculty of Science, Medicine and Health - Papers: part A

Background Women with large breasts frequently experience upper torso pain secondary to their breast size. Evidence is lacking on the underlying causes of this pain. This study investigated whether upper torso pain and musculoskeletal structure and function differed between women with large breasts and women with small breasts. Methods A linear regression, adjusting for body mass, compared the upper torso pain, thoracic flexion torque due to breast mass, thoracic kyphosis, shoulder active range-of-motion, and scapular retraction muscle strength of 27 women with large breasts (bilateral breast volume > 1200 ml, age 45.9 y SD 9.9 y, BMI 29.0 kg/m 2 SD …

Online Ozonolysis Combined With Ion Mobility-Mass Spectrometry Provides A New Platform For Lipid Isomer Analyses, Berwyck L. J Poad, Xueyun Zheng, Todd W. Mitchell, Richard D. Smith, Erin S. Baker, Stephen J. Blanksby

Faculty of Science, Medicine and Health - Papers: part A

One of the most significant challenges in contemporary lipidomics lies in the separation and identification of lipid isomers that differ only in site(s) of unsaturation or geometric configuration of the carbon-carbon double bonds. While analytical separation techniques including ion mobility spectrometry (IMS) and liquid chromatography (LC) can separate isomeric lipids under appropriate conditions, conventional tandem mass spectrometry cannot provide unequivocal identification. To address this challenge, we have implemented ozone-induced dissociation (OzID) in-line with LC, IMS, and high resolution mass spectrometry. Modification of an IMS-capable quadrupole time-of-flight mass spectrometer was undertaken to allow the introduction of ozone into the high-pressure trapping …

Patterns Of Signs That Telephone Crisis Support Workers Associate With Suicide Risk In Telephone Crisis Line Callers, Tara Hunt, Coralie J. Wilson, Peter Caputi, Ian G. Wilson, Alan Woodward

Faculty of Science, Medicine and Health - Papers: part A

Signs of suicide are commonly used in suicide intervention training to assist the identification of those at imminent risk for suicide. Signs of suicide may be particularly important to telephone crisis-line workers (TCWs), who have little background information to identify the presence of suicidality if the caller is unable or unwilling to express suicidal intent. Although signs of suicide are argued to be only meaningful as a pattern, there is a paucity of research that has examined whether TCWs use patterns of signs to decide whether a caller might be suicidal, and whether these are influenced by caller characteristics such …

Self-Organized Nanostructure Modified Microelectrode For Sensitive Electrochemical Glutamate Detection In Stem Cells-Derived Brain Organoids, Babak Nasr, Rachael Chatterton, Jason Yong, Pegah Jamshidi, Giovanna M. D'Abaco, Andrew R. Bjorksten, Omid Kavehei, Gursharan Chana, Mirella Dottori, Efstratios Skafidas

Faculty of Science, Medicine and Health - Papers: part A

Neurons release neurotransmitters such as glutamate to communicate with each other and to coordinate brain functioning. As increased glutamate release is indicative of neuronal maturation and activity, a system that can measure glutamate levels over time within the same tissue and/or culture system is highly advantageous for neurodevelopmental investigation. To address such challenges, we develop for the first time a convenient method to realize functionalized borosilicate glass capillaries with nanostructured texture as an electrochemical biosensor to detect glutamate release from cerebral organoids generated from human embryonic stem cells (hESC) that mimic various brain regions. The biosensor shows a clear catalytic …

Gas-Phase Oxidation Of The Protonated Uracil-5-Yl Radical Cation, James Bezzina, Matthew Prendergast, Stephen J. Blanksby, Adam J. Trevitt

Faculty of Science, Medicine and Health - Papers: part A

This study targets the kinetics and product detection of the gas-phase oxidation reaction of the protonated 5-dehydrouracil (uracil-5-yl) distonic radical cation using ion-trap mass spectrometry. Protonated 5-dehydrouracil radical ions (5-dehydrouracilH⁺ radical ion, m/z 112) are produced within an ion trap by laser photolysis of protonated 5-iodouracil. Storage of the 5-dehydrouracilH⁺ radical ion in the presence of controlled concentration of O₂ reveals two main products. The major reaction product pathway is assigned as the formation of protonated 2-hydroxypyrimidine-4,5-dione (m/z 127) + ^•OH. A second product ion (m/z 99), putatively assigned as a five-member-ring ketone structure, is tentatively …

Single-Grain Dating Of Potassium-Rich Feldspar Grains: Towards A Global Standardised Growth Curve For The Post-Ir Irsl Signal, Bo Li, Zenobia Jacobs, Richard G. Roberts, Sheng-Hua Li

Faculty of Science, Medicine and Health - Papers: part A

Potassium-rich feldspar (K-feldspar) grains were extracted from 28 sediment samples from sites in Asia, Europe and Africa and the dose response curves - or growth curves - were constructed from the post-infrared infrared stimulated luminescence (pIRIR) signals emitted by individual grains. The samples exhibit large between-grain variation in both pIRIR signal intensity and the shape of the corresponding growth curves; the latter can be largely explained as a result of measurement uncertainties, including counting statistics and instrumental irreproducibility. This between-grain variation can be reduced by applying a least-squares normalisation (LS-normalisation) procedure, which allows a common growth curve - or global …

Monitoring The Extent Of Vertical And Lateral Movement Of Human Decomposition Products Through Sediment Using Cholesterol As A Biomarker, Susan Luong, Shari Forbes, James F. Wallman, Richard G. Roberts

Faculty of Science, Medicine and Health - Papers: part A

Due to the lack of human decomposition research facilities available in different geographical regions, the extent of movement of human decomposition products from a cadaver into various sedimentary environments, in different climates, has not been able to be studied in detail. In our study, a human cadaver was placed on the surface of a designated plot at the Australian Facility for Taphonomic Experimental Research (AFTER), the only human decomposition facility in Australia, where the natural process of decomposition was allowed to progress over 14 days in the Australian summer. Sediment columns (approximately 1 m deep) were collected at lateral distances …

Empowerment: The Experience Of Recovery Camp For People Living With A Mental Illness, Caroline Picton, Christopher F. Patterson, Lorna Moxham, Ellie K. Taylor, Dana J. Perlman, Renee M. Brighton, Tim Heffernan

Faculty of Science, Medicine and Health - Papers: part A

Background: Mental health recovery is still largely clinically defined and as such can lack person centeredness. To address this, recovery oriented experiences are required which recognise the holistic and diverse needs of individuals.

Aim: The aim of the study was to examine the experiences of people living with a mental illness who participated in a recovery oriented program called Recovery Camp. The study aimed to examine how the program may have related and contributed to their mental health recovery.

Methods: A descriptive phenomenological approach guided the study. Consenting participants (n = 5) were interviewed and asked about …

Positive Ageing On Our Mind - An Initiative Called Afia (Age Friendly Illawarra Alliance), Lorna Moxham

Faculty of Science, Medicine and Health - Papers: part A

Ageing is everyone's business, after all, none of us are getting younger. This assertion is reflected in the nursing workforce with the Department of Health telling us that the overall ageing workforce is reflected in both the increasing average age of nurses from 44.3 years in 2009 to 44.6 years in 2012 and the increasing percentage of those aged 55 years and over from 19.8% in 2009 to 23.1% in 2012.

Exercise And Psychological Benefits For Older People, Rebekkah Middleton, Lorna Moxham, Dominique R. Parrish

Faculty of Science, Medicine and Health - Papers: part A

The literature establishes that older people benefit not only physically, but cognitively and socially from being engaged in community recreational activities. Community recreational activities support healthy ageing (Young et al. 2015 p2), and allow older people to maintain cognitive abilities, improve self-belief, and quality of life indicators (Balducci et al. 2014).

Work Satisfaction And Future Career Intentions Of Experienced Nurses Transitioning To Primary Health Care Employment, Christine Ashley, Kathleen Peters, Angela M. Brown, Elizabeth J. Halcomb

Faculty of Science, Medicine and Health - Papers: part A

Aim: To explore registered nurses' reflections on transitioning from acute to primary health care employment, and future career intentions.

Background: Reforms in primary health care have resulted in increasing demands for a skilled primary health care nursing workforce. To meet shortfalls, acute care nurses are being recruited to primary health care employment, yet little is known about levels of satisfaction and future career intentions.

Method: A sequential mixed methods study consisting of a survey and semi-structured interviews with nurses who transition to primary health care.

Results: Most reported positive experiences, valuing work/life balance, role diversity and …

International Ocean Discovery Program Expedition 369 Preliminary Report: Australia Cretaceous Climate And Tectonics: Tectonic, Paleoclimate, And Paleoceanographic History Of High-Latitude Southern Margins Of Australia During The Cretaceous, Brian T. Huber, Richard W. Hobbs, Kara A. Bogus, Sietske Batenburg, H-J Brumsack, Rodrigo Do Monte Guerra, Kirsty Edgar, Trine Edvardsen, Dennis Harry, Takashi Hasegawa, Shannon Haynes, Tao Jiang, Matthew M. Jones, Junichiro Kuroda, Eun-Young Lee, Y-X Li, Kenneth Macleod, Alessandro Maritati, Mathieu Martinez, Lauren O'Connor, Maria Petrizzo, Tracy Quan, Carl Richter, Laurent Riquier, Gabriel Tagliaro, Maria Tejada, Carmine Wainman, David K. Watkins, Lloyd T. White, Erik Wolfgring, Zhaokai Xu

Faculty of Science, Medicine and Health - Papers: part A

The tectonic and paleoceanographic setting of the Great Australian Bight (GAB) and the Mentelle Basin (MB; adjacent to Naturaliste Plateau) offered an outstanding opportunity to investigate Cretaceous and Cenozoic climate change and ocean dynamics during the last phase of breakup among remnant Gondwana continents. Sediment recovered from sites in both regions during International Ocean Discovery Program Expedition 369 will provide a new perspective on Earth's temperature variation at sub-polar latitudes (60°-62°S) across the extremes of the mid-Cretaceous hot greenhouse climate and the cooling that followed. The primary goals of the expedition were to: * Investigate the timing and causes for …

A Reassessment Of Mycophenolic Acid As A Lead Compound For The Development Of Inhibitors Of Chikungunya Virus Replication, Adel Rashad, Johan Neyts, Pieter Leyssen, Paul A. Keller

Faculty of Science, Medicine and Health - Papers: part A

Mycophenolic acid (MPA) has been previously reported as an inhibitor of the chikugunya virus (CHIKV) with an EC₅₀ value of 0.2 μM. We used MPA as a lead compound designing and synthesizing a series of isatins and benzolactones in a typical medicinal chemistry program. The synthesis and testing of 19 derivatives produced compounds with no desired activity which prompted us to retest the lead compound, MPA. We can reveal that MPA shows no anti-CHIKV activity and therefore needs to be reassessed as a lead compound for this target.

Association Between Maternal Sense Of Competence And Self-Efficacy In Primiparous Women During Postpartum Period, Marzieh Bagherinia, Shahla Meedya, Mojgan Mirghafourvand

Faculty of Science, Medicine and Health - Papers: part A

Background: When women's' lives enter a new phase after childbirth, they need to adapt to it in order to accept their motherhood role. Maternal competency depends on the mother's perception of her maternal role and the ability to attain and fulfill it. The aim of this study was to examine the association between maternal sense of competence and self-efficacy in the postpartum period.

Methods: In this cross-sectional study, 305 Iranian women were selected randomly via a two-stage cluster sampling method at the end of the 4th postpartum month. Data were collected from August 2016 to January 2017 and …

Low Intensity Blood Parasite Infections Do Not Reduce The Aerobic Performance Of Migratory Birds, Steffen Hahn, Silke Bauer, Dimitar Dimitrov, Tamara Emmenegger, Karina Ivanova, Pavel Zehtindjiev, William A. Buttemer

Faculty of Science, Medicine and Health - Papers: part A

Blood parasites (Haemosporidia) are thought to impair the flight performance of infected animals, and therefore, infected birds are expected to differ from their non-infected counterparts in migratory capacity. Since haemosporidians invade host erythrocytes, it is commonly assumed that infected individuals will have compromised aerobic capacity, but this has not been examined in free-living birds. We tested if haemosporidian infections affect aerobic performance by examining metabolic rates and exercise endurance in migratory great reed warblers (Acrocephalus arundinaceus) experimentally treated with Plasmodium relictum pGRW04 and in naturally infected wild birds over consecutive life-history stages. We found no effect of acute or chronic …