Social and Behavioral Sciences Commons^™

Research Progress In High-Throughput Phenotype Testing Technology And Equipment For Engineering Cells Based On Microfluidics, Shuang Li, Xiaojie Guo, Haibo Chen, Sisi Chen, Xin Da, Zhenghui Li, Qinxiu Liu, Yi Wang, Xinhui Xing, Chong Zhang

Bulletin of Chinese Academy of Sciences (Chinese Version)

Engineering cells are a core component of green bio-manufacturing. The efficient testing and acquisition of engineering cells with the desired phenotype is a critical factor in the successful implementation of bio-manufacturing. In recent years, based on microfluidics technologies, non-culture type single-cell phenotype high-throughput test equipment and culture type phenotype high-throughput test equipment for the growth and metabolism of single cell in a bioreactor have been developed such as microdroplet and microchamber, realizing high-throughput, automated, miniaturized, and integrated testing of the phenotypes of engineering cells and providing a powerful tool for the breeding of engineering cells. This review systematically compiles the …

Bioprocess Engineering And Intelligent Biomanufacturing, Guan Wang, Yingping Zhuang

Bulletin of Chinese Academy of Sciences (Chinese Version)

In the era of rapid development of synthetic biology, biomanufacturing, as a bridge between life sciences and engineering technologies, is gradually demonstrating its extraordinary potential to reshape industrial landscapes. However, challenges such as production efficiency, cost control, and process monitoring still hinder the smooth transition from laboratory innovations to industrial-scale implementation. Intelligent biomanufacturing has emerged as a new form of productive force, offering innovative solutions to these problems. This study reviews the latest advances in bioprocess engineering and intelligent biomanufacturing, focusing on three key technological systems: intelligent sensing, intelligent analysis, and intelligent control. Intelligent sensing technology acts as the “eyes” …

Analysis And Reflections On Key Platform Facilities Construction Of Global Biomanufacturing Industry, Xiaoyan Wu, Fang Chen, Yaoying Shan, Anjing Lu

Bulletin of Chinese Academy of Sciences (Chinese Version)

Biomanufacturing, an emerging production method, is becoming a significant trend in global economic development and has garnered widespread international attention. Platform facilities are vital to the biomanufacturing industry’s development, serving as both the foundation for technological innovation and the bridge between research outcomes and practical applications. This study analyzes three key types of platform facilities and their operational mechanisms: technology innovation platforms (exemplified by the U.S. Agile BioFoundry), pilot-scale platforms (represented by European Bio Base Europe Pilot Plant), and industry incubation platforms (illustrated by the UK SynbiCITE). Drawing from these successful examples and examining China’s current platform infrastructure, this paper …

Research On Innovative Development Path And Policy Guarantee Of China’S Synthetic Biology Industry, Hongjun Geng, Chang Wang

Bulletin of Chinese Academy of Sciences (Chinese Version)

Synthetic biology is hailed as the third revolution in life sciences after the discovery of the DNA double helix structure and genomic technology, and is the core driving force for the leapfrog development of next-generation biomanufacturing and the future bioeconomy, opening up an opportunity window for the reshaping of the global manufacturing map. How to strategically position the synthesis biology industry and seize the strategic high ground in the industry is a core topic of interest for global science and technology powers and manufacturing powers. Based on the identification of problems in the development of China’s synthesis biology industry, this …

Artificial Intelligence Driven Information Technology System Restructuring And Reconstruction—Review Of Information Science & Technology In China: A Roadmap To 2050, Xuehai Hong

Bulletin of Chinese Academy of Sciences (Chinese Version)

The Information Science & Technology in China: A Roadmap to 2050 and Information Technology: Accelerating the Integration of Human Machine Things have predicted the long-term development of China’s information technology field. This study reviews the development and changes in the field of information technology in the past 15 years, and compares them with the initial predictions, pointing out that some important judgments made at the beginning were in line with expectations. In recent years, the global development of information technology has entered a slow period, while the rapid evolution of the new generation of artificial intelligence will bring new opportunities …

Scientific Approach To Building A Highland Of Ecological Civilization In Xizang Of China, Xiaodan Wang, Jianxin Zhang, Da Wei, Hui Zhao, Jiangtao Hong, Yuling Liang, Yahui Qi, Zhengrong Yuan

Bulletin of Chinese Academy of Sciences (Chinese Version)

Xizang, which plays an important barrier role in maintaining national ecological security, is a unique region that ensures China’s sustainable development and leads the construction of national ecological civilization. The Seventh Central Conference on the Work of Xizang has set clear goals and specific requirements for building an ecological civilization highland on the Qinghai-Xizang Plateau, which were identified as a new mission and task of Xizang government for environmental protection and sustainable development in the new era. Based on the previous research achievements about national ecological security barrier, this work further carried out the systematic study of ecological civilization highland …

Internal Logic And Policy Recommendations Of Big Data To Support High-Quality Development Of Modern Agricultural Industry, Yingming Li, Zitong Wang, Mingyue Wang, Shiyi Liu

Bulletin of Chinese Academy of Sciences (Chinese Version)

Clarifying the internal logic of big data to support modern agricultural production is helpful to cultivate and develop new quality productive forces in agriculture. From the perspective of economics, this study proposes that the role of big data in modern agricultural production is mainly reflected in two levels. Firstly, it improves the total factor productivity of the traditional agricultural production function. Secondly, it changes the factor endowment structure of agricultural production and forms a new agricultural production function. Based on these, the realization form of big data to support modern agricultural production can be summarized as improving the efficiency of …

Strengthen Research On Environmental Control Technologies And Management Policies For Emerging Contaminants In China, Ying Ma, Xiang Li, Yongming Luo

Bulletin of Chinese Academy of Sciences (Chinese Version)

The prevention and management of emerging contaminants (ECs) have become critical measures in China’s battle against environmental pollution. This study focuses on the environmental control technologies and policy governance related to emerging contaminants (ECs), analyzing their environmental pathways and challenges to public health, and highlighting advancements and limitations in current physical, chemical, and biological control technologies. Based on a comprehensive analysis of international policies and regulations on ECs control, the study identifies existing challenges and shortcomings in domestic management. Recommendations are proposed to enhance research on environmental control technologies and policies for ECs in China, aiming to provide insights for …

Development And Utilization Of Mineral Resources In The Arctic And China’S Strategic Countermeasures, Yina Su

Bulletin of Chinese Academy of Sciences (Chinese Version)

There are abundant strategic mineral resources as oil, gas, iron ore, copper, and nickel in the Arctic region. If the Arctic routes can be opened in the future, they will become another important transportation channels connecting the Pacific and Atlantic Oceans, following the Panama Canal and the Suez Canal, which may reshape the world’s maritime trade and transportation pattern. With the development of science and technology, increase in mineral resources consumption and changes in the international environment, the strategic position of the Arctic region is increasingly elevated, and the United States, Russia and some other countries of the European Union …

Redesign And De Novo Design Of Circular Blue Bioindustry, Wei Zhang, Shufeng Zhang, Hantao Zhou, Minhan Dai

Bulletin of Chinese Academy of Sciences (Chinese Version)

The future marine bioindustry, which features advanced green intelligent biomanufacturing and high-value marine bioproducts, is a strategically emerging marine industry. This study proposes a new industrial development model for the circular blue bioindustry, founded on simultaneously optimizing the sustainable utilization of marine bioresources and protecting the ecological environment. Through in-depth analysis of the current situation, challenges, and potential development opportunities of the global and Chinese marine bioindustries underpinning sustainable development, theoretical framework, approaches and implementation pathways have been established to redesign the existing marine bioindustry and de novo design of the emerging marine bioindustry. Future key development priorities are suggested …

Ai Helps To Establish A New Paradigm For Scientific Research, Weinan E

Bulletin of Chinese Academy of Sciences (Chinese Version)

The main purpose of scientific research is to discover fundamental principles and solve practical problems. Although tremendous progress has been made on both fronts, the lack of effective tools and efficient organizational structure still stands as the main bottleneck for scientific progress. The rapid development of artificial intelligence (AI) offers a new possibility. In recent years, deep learning has had an impressive performance, both in helping to solve fundamental scientific problems and in improving the effectiveness of scientific research tools. A new set of infrastructure is emerging, leading us to a new paradigm, the“Android paradigm”, for doing scientific research.

Ai4r: The Fifth Scientific Research Paradigm, Guojie Li

Bulletin of Chinese Academy of Sciences (Chinese Version)

This article refers to “AI for Research（AI4R）” as the fifth research paradigm and summarizes its characteristics, including: (1) the fully integration of artificial intelligence into various scientific and technology researches; (2) machine intelligence has become an integral part of scientific research; (3) effectively handles the combinatorial explosion problem with high computational complexity; (4) probability and statistical models play a greater role in scientific research; (5) realize the integration of four existing research paradigms, cross disciplinary cooperation has become the mainstream research method; (6) scientific research relies more on large research platforms characterized by large models. This article points out that …

Digital Scientists And Parallel Sciences: The Origin And Goal Of Ai For Science And Science For Ai, Feiyue Wang, Yutong Wang

Bulletin of Chinese Academy of Sciences (Chinese Version)

Based on recent development in foundation model, parallel intelligence, decentralized science (DeSci), and other artificial intelligence (AI) technologies, from AI for Science (AI4S) to Science for AI (S4AI), this study discusses parallel sciences and digital scientists, and their impact and significance in paradigm shift for research and development as well as Industry 5.0 and intelligent industry, which demonstrate that paradigm shift is emerging and accelerating, and we must be prepared.

Computing System For Simulation Intelligence, Guangming Tan, Weile Jia, Zhan Wang, Guojun Yuan, En Shao, Ninghui Sun

Bulletin of Chinese Academy of Sciences (Chinese Version)

This study refers computer simulation in scientific research to as scientific simulation. Based on its narrow and broad definitions, this study divides scientific simulation into three stages: numerical computation, simulation intelligence, and science brain. Now, scientific simulation is entering the era of simulation intelligence, i. e., driven by scientific big data and artificial intelligence technology, scientific simulation is shifting from traditional numerical simulation to simulation integrated with artificial intelligence. In order to understand what the right computing system for simulation intelligence is, the design guidelines, basic methods, and key technical problems are discussed.

Large Model-Driven, Human-Computer Collaborative Robotic Ai-Chemist Cloud Facility, Yuanyuan Chong, Shuo Feng, Song Wang, Jun Jiang

Bulletin of Chinese Academy of Sciences (Chinese Version)

At present, chemical science is facing unprecedented opportunities and challenges due to the technological changes brought by artificial intelligence. In order to promote the paradigm shift in chemical research, this study proposes the construction plan of the robotic AI-chemist cloud facility. This system realizes a new paradigm of scientific research by collecting multi-channel data to build a database, developing large scientific models enhanced by chemical knowledge, constructing clusters of robotic facilities, and building an intelligent management decision system, which will dramatically improve the efficiency of scientific research and solve scientific problems in terminal applications. This infrastructure is expected to change …

A New Paradigm Of Life Science Research Driven By Artificial Intelligence, Xin Li, Hanchao Yu

Bulletin of Chinese Academy of Sciences (Chinese Version)

The rapid development of biotechnology and information technology has brought life sciences into a new era of data explosion. The traditional life science research paradigm struggles to reveal the fundamental rules of complex biological systems from rapidly growing biological big data. As artificial intelligence continues to achieve disruptive breakthroughs in life science, a new paradigm driven by AI is emerging. This study delves into typical examples of life science research driven by AI, proposes the concept and key elements of the new life science research paradigm, elaborates on the cutting-edge of life science research under this new paradigm, and discusses …

Ai For Technology: Applied Practices And Future Perspectives Of Technological Intelligence In High Tech Areas, Yunji Chen, Qi Guo

Bulletin of Chinese Academy of Sciences (Chinese Version)

As the core of the fifth research paradigm, AI for Science has been widely used in multiple research fields of natural sciences and high technologies. In contrast to that the application of AI in natural sciences mainly focuses on discovering new theories, principles, and laws, the application of AI in high technologies mainly focuses on creating new plans, tools, and products, in order to resolve concrete problems in related fields. This study first summarizes the typical characteristics and scientific problems of the application of AI in high technologies, i.e., AI for Technology, and then introduces a successful case study of …

Building New Paradigm Of Digital Intelligence Security For New Development Pattern, Xiaoguang Yang, Yang Wu, Xingwei Zhang, Xiaolong Zheng

Bulletin of Chinese Academy of Sciences (Chinese Version)

After the 20th National Congress of the Communist Party of China, China has entered a new era of development. Simultaneously, the rapid advancement and extensive application of artificial intelligent technologies have activated a new wave of economic potential and brought about new security challenges to socioeconomic development. This study firstly analyzes the characteristics of the new development pattern in global contexts, and examines the risks and challenges of digital intelligence security (DIS) under the new pattern, encompassing technological security and personal security at the micro-level, as well as economic security, social security, and cultural security at the macro-level. Based on …

Ai For Science: Ai Enabled Scientific Facility Transforms Fundamental Research, Xiaokang Yang, Yanyan Xu, Lu Chen, Yunbo Wang, Yue Gao, Jidong Tian, Kai Yu, Yaohui Jin, Hong Mei

Bulletin of Chinese Academy of Sciences (Chinese Version)

In recent years, artificial intelligence (AI) has achieved numerous disruptive breakthroughs in frontier scientific and technological fields, such as AlphaFold2 for protein structure prediction, intelligent control of nuclear fusion, and drug design for COVID-19. These achievements indicate that AI for Science is becoming a new paradigm in research. To achieve fundamental scientific innovation and major technological breakthroughs in the era of intelligence, two core issues should be addressed: 1) how to harness the generality and creativity of the new-generation of AI, especially generative AI and large language models (LLMs), to promote the formation of new paradigms; 2) how to empower …

Strategic Research On Information Technology Promoting National Governance Modernization—Review On The S70th Xiangshan Science Conferences, Chao Zhang, Weiyu Duan, Kaihua Chen, Xiaoguang Yang, Yuntao Long

Bulletin of Chinese Academy of Sciences (Chinese Version)

This study systematically summarizes the reports and speeches of the S70th Xiangshan Science Conferences on the theme of “Strategic Research on Information Technology Promoting the National Governance Modernization” and summarizes the consensus of the conference in the following three aspects. (1) Important progress and achievements have been made in the four typical areas, i.e., smart justice, internet governance, data governance, and emergency management. (2) Using information technology to promote the modernization of national governance is confronted with unprecedented opportunities and challenges. And (3) it is necessary to take a series of effective measures to promote information technology to facilitate the …

The Santa Clara, 2024-01-19, Santa Clara University

The Santa Clara

No abstract provided.

The Shifting Landscape Of Adolescent Wellness In Boarding Schools: Can Time Spent Off Screens And Outdoors Improve Adolescent Wellbeing?, Kristen H. Peterson

Dartmouth College Master’s Theses

For nearly twenty years I have worked directly with adolescents as an independent school educator. Whether in the classroom, on the field, or in the dorm, I have observed and supported students through their middle and high school experiences. During this time, I have witnessed an alarming shift in adolescent physical, emotional, and social wellbeing. Concurrently, I have observed a dramatic increase in the amount of time students spend using screen-based devices, and a decrease in their time spent outdoors.

Using research to ground my anecdotal accounts in empirical understanding, my thesis examines whether or not screen use might help …

Evaluation Of Seven Satellite-Based And Two Reanalysis Global Terrestrial Evapotranspiration Products, Zijing Xie, Yunjun Yao, Qingxin Tang, Meng Liu, Joshua B. Fisher, Jiquan Chen, Xiaotong Zhang, Kun Jia, Yufu Li, Ke Shang, Bo Jiang, Junming Yang, Ruiyang Yu, Xueyi Zhang, Xiaozheng Guo, Lu Liu, Jing Ning, Jiahui Fan, Lilin Zhang

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

Although comprehensive evaluation of different types of global terrestrial evapotranspiration (ET) products has been conducted, the satellite remote sensing techniques have prompted the development of several available global ET products, warranting a reassessment as products continue to evolve. Recently, we produced the long-term Global LAnd Surface Satellite (GLASS) ET product, but there is a lack of comparison and evaluation with other ET products and EC observations on a global scale. In this study, we evaluated the accuracy and uncertainty of seven satellite-based (GLASS-AVHRR, GLASS-MODIS, BESS, FLUXCOM, GLEAM, MOD16, and PML_V2) and two reanalysis (ERA5 and MERRA2) global terrestrial ET products …

Program Requirements For Beef Cattle Certified As Usda Organic, Carsten Loseke, Elliott James Dennis

Cornhusker Economics

This document provides an overview of the use and production of the USDA Certified Organic program for the beef cattle industry, with an emphasis on the state of Nebraska. We detail what cattle qualify, feed requirements, medical and health standards of cattle, and premiums paid by consumers for USDA certified organic products. All information is taken from the Organic Foods Production Act Provisions available in the Federal Register.

Integrating Moral Norms And Stewardship Identity Into The Theory Of Planned Behavior To Understand Altruistic Conservation Behavior Among Hunters In Southwestern Utah (Usa), Jacob C. Richards, Zachary D. Miller, Russell Norvell, Jordan W. Smith

Environment and Society Faculty Publications

We integrate moral norms and stewardship identity into the Theory of Planned Behavior (TPB) to predict the use of non-lead ammunition in the California condor recovery zone of southwestern Utah. Data were collected from licensed hunters via an online survey. Structural equation models of the TPB without and with the moral norms and stewardship identity constructs were compared to evaluate the utility of integrating these constructs into the TPB. Moral norms did have a significant direct influence on hunters’ behavioral intentions. Both moral norms and stewardship identity had significant indirect influences on behavioral intentions via the core constructs of the …

Meet Scite, “Chatgpt For Research”, A New Artificial Intelligence (Ai) Tool Available Via Clemson Libraries, Jennifer Groff, Shelby Carroll

Clemson Teaching Excellence Conference 2024: Teaching in the Age of AI

No abstract provided.

Odes And Mandatory Voting, Christoph Borgers, Natasa Dragovic, Anna Haensch, Arkadz Kirshtein, Lilla Orr

CODEE Journal

This paper presents mathematics relevant to the question whether voting should be mandatory. Assuming a static distribution of voters’ political beliefs, we model how politicians might adjust their positions to raise their share of the vote. Various scenarios can be explored using our app at https: //centrism.streamlit.app/. Abstentions are found to have great impact on the dynamics of candidates, and in particular to introduce the possibility of discontinuous jumps in optimal candidate positions. This is an unusual application of ODEs. We hope that it might help engage some students who may find it harder to connect with the more customary …

Ode Models Of Wealth Concentration And Taxation, Bruce Boghosian, Christoph Borgers

CODEE Journal

We refer to an individual holding a non-negligible fraction of the country’s total wealth as an oligarch. We explain how a model due to Boghosian et al. can be used to explore the effects of taxation on the emergence of oligarchs. The model suggests that oligarchs will emerge when wealth taxation is below a certain threshold, not when it is above the threshold. The underlying mechanism is a transcritical bifurcation. The model also suggests that taxation of income and capital gains alone cannot prevent the emergence of oligarchs. We suggest several opportunities for students to explore modifications of the model.

Fitting A Covid-19 Model Incorporating Senses Of Safety And Caution To Local Data From Spartanburg County, South Carolina, D. Chloe Griffin, Amanda Mangum

CODEE Journal

Common mechanistic models include Susceptible-Infected-Removed (SIR) and Susceptible-Exposed-Infected-Removed (SEIR) models. These models in their basic forms have generally failed to capture the nature of the COVID-19 pandemic's multiple waves and do not take into account public policies such as social distancing, mask mandates, and the ``Stay-at-Home'' orders implemented in early 2020. While the Susceptible-Vaccinated-Infected-Recovered-Deceased (SVIRD) model only adds two more compartments to the SIR model, the inclusion of time-dependent parameters allows for the model to better capture the first two waves of the COVID-19 pandemic when surveillance testing was common practice for a large portion of the population. We find …

Aftdc 2024 Session I English.- Decoding Complexity: Visualizing The Trans-Disciplinary Communication (Tdc) Logarithmic Spiral, Jasmin Cowin

Trans-Disciplinary Communication

No abstract provided.