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Full-Text Articles in Social and Behavioral Sciences

Neurocognitive Correlates Of Cerebellar Volumetric Alterations In Youth With Pediatric Bipolar Spectrum Disorders And Bipolar Offspring, Kirti Saxena, Alessio Simonetti, Christopher D Verrico, Delfina Janiri, Marco Di Nicola, Antonello Catinari, Sherin Kurian, Johanna Saxena, Benson Mwangi, Jair C Soares Jan 2023

Neurocognitive Correlates Of Cerebellar Volumetric Alterations In Youth With Pediatric Bipolar Spectrum Disorders And Bipolar Offspring, Kirti Saxena, Alessio Simonetti, Christopher D Verrico, Delfina Janiri, Marco Di Nicola, Antonello Catinari, Sherin Kurian, Johanna Saxena, Benson Mwangi, Jair C Soares

Faculty, Staff and Student Publications

BACKGROUND: Emerging evidence points towards the involvement of the cerebellum in the processing of emotions and pathophysiology of mood disorders. However, cerebellar and related cognitive alterations in youth with pediatric bipolar disorder (PBD) and those at high risk to develop the disorder, such as bipolar offspring (BD-OFF) are not clearly defined.

OBJECTIVE: To investigate cerebellar gray and white matter volumes, cognition, and their relationship in youth with PBD and BD-OFF.

METHODS: Thirty youth (7 to 17 years, inclusive) with PBD, 30 BD-OFF and 40 healthy controls (HC) were recruited. Study participants underwent a computer-based cognitive battery assessing affective processing, executive …


A Population-Based Assessment Of Metastatic Hepatoblastoma In Texas Reveals Ethnic Disparities, Andres F Espinoza, Michael E Scheurer, Tiffany M Chambers, Sanjeev A Vasudevan, Philip J Lupo Jan 2023

A Population-Based Assessment Of Metastatic Hepatoblastoma In Texas Reveals Ethnic Disparities, Andres F Espinoza, Michael E Scheurer, Tiffany M Chambers, Sanjeev A Vasudevan, Philip J Lupo

Faculty, Staff and Students Publications

BACKGROUND: Hepatoblastoma (HB) is the most common primary liver cancer in children with emerging evidence that incidence is increasing globally. While overall survival for low risk hepatoblastoma is >90%, children with metastatic disease have worse survival. As identifying factors associated with high-risk disease is critical for improving outcomes for these children, a need for a further understanding of the epidemiology of hepatoblastoma is warranted. Therefore, we conducted a population-based epidemiologic study of hepatoblastoma in Texas, a large state characterized by ethnic and geographic diversity.

METHODS: Information on children diagnosed with hepatoblastoma at 0-19 years of age for the period of …


Development Of Competency-Based Online Genomic Medicine Training (Cogent), Susanne B Haga, Wendy K Chung, Luis A Cubano, Timothy B Curry, Philip E Empey, Geoffrey S Ginsburg, Kara Mangold, Christina Y Miyake, Siddharth K Prakash, Laura B Ramsey, Robb Rowley, Carolyn R Rohrer Vitek, Todd C Skaar, Julia Wynn, Teri A Manolio Jan 2023

Development Of Competency-Based Online Genomic Medicine Training (Cogent), Susanne B Haga, Wendy K Chung, Luis A Cubano, Timothy B Curry, Philip E Empey, Geoffrey S Ginsburg, Kara Mangold, Christina Y Miyake, Siddharth K Prakash, Laura B Ramsey, Robb Rowley, Carolyn R Rohrer Vitek, Todd C Skaar, Julia Wynn, Teri A Manolio

Faculty, Staff and Student Publications

The fields of genetics and genomics have greatly expanded across medicine through the development of new technologies that have revealed genetic contributions to a wide array of traits and diseases. Thus, the development of widely available educational resources for all healthcare providers is essential to ensure the timely and appropriate utilization of genetics and genomics patient care. In 2020, the National Human Genome Research Institute released a call for new proposals to develop accessible, sustainable online education for health providers. This paper describes the efforts of the six teams awarded to reach the goal of providing genetic and genomic training …


Effects Of Development On Hpa Function Following Pubertal Stress, Brittany D. Elliott Jan 2023

Effects Of Development On Hpa Function Following Pubertal Stress, Brittany D. Elliott

Graduate Theses, Dissertations, and Problem Reports (ETD)

For women, two of the greatest risk factors for affective disorders are adversity experienced during puberty and later becoming pregnant. We have created a translationally relevant mouse model where we address these complex risk factors. Previously, we discovered that pregnant mice (dams) that experienced chronic variable stress (CVS) during puberty display a blunted hypothalamic-pituitary-adrenal (HPA) response when exposed to an acute stressor. Interestingly, this alteration only first becomes apparent during pregnancy, which is a sensitive period for these effects due to normative neuroendocrine changes. Further investigation of the mechanisms underlying this dysfunction revealed altered gene expression in the paraventricular nucleus …


Production, Best Management Practices, And Market Impacts Of Forest Biomass Harvest And Collection In The Mid-Atlantic Region, William E. Smith Jan 2023

Production, Best Management Practices, And Market Impacts Of Forest Biomass Harvest And Collection In The Mid-Atlantic Region, William E. Smith

Graduate Theses, Dissertations, and Problem Reports (ETD)

Time motion studies were conducted at five mid-Atlantic sites that spanned various operations in West Virginia, Ohio, and Pennsylvania. The harvest systems included integrated harvests where chips were produced in the forest, roundwood systems where only roundwood was produced, and a centralized chipping system. The study collected overall productivity and machine utilization data at the various harvesting operations. The cost per green ton of woody biomass ranged from $18.46 to $39.8 resulting in an average of $30.33 among the five systems. Hauling had the highest average price per green ton at $9.10, while loading had the lowest at $1.73 per …


Effects Of Combined Ethanol And Nicotine Administration On Delay Discounting In Male And Female Sprague-Dawley Rats, Rebecca Lillian Chalme Jan 2023

Effects Of Combined Ethanol And Nicotine Administration On Delay Discounting In Male And Female Sprague-Dawley Rats, Rebecca Lillian Chalme

Graduate Theses, Dissertations, and Problem Reports (ETD)

Ethanol (EtOH) and nicotine (NIC) are among the most commonly used and co-used drugs in the world. Co-use occurs in people who use one or both drugs chronically, but also in people who only consume one or both drugs acutely, often in a “bingeing and chipping” pattern. Given that each drug on its own has previously been shown to affect impulsive choice in delay-discounting procedures, with some indication that drug effects could vary by sex, the purpose of the present experiments was to investigate effects of combined EtOH and NIC at a range of dose combinations on delay discounting in …


Cue Reactivity In Electronic Cigarette Users With Sign-Tracking Or Goal-Tracking Behaviors, Polina Krom Jan 2023

Cue Reactivity In Electronic Cigarette Users With Sign-Tracking Or Goal-Tracking Behaviors, Polina Krom

Graduate Theses, Dissertations, and Problem Reports (ETD)

Polina Krom

Cue reactivity is an important predictor of addiction course and relapse. However, cue reactivity is only observed after an addiction develops. As such, it is unclear to what degree cue reactivity represents a state stemming from the addiction process versus a trait-like propensity towards developing cue-reward associations. Work in animal models has pointed to important individual differences in trait-like inclination to attribute incentive salience to reward-predictive cues that is associated with addiction-relevant behavioral and neurobiological features. These individual differences manifest as sign-tracking (ST) and goal-tracking (GT) behaviors during Pavlovian conditioning. Little research has attempted to translate ST and …


Parent And Adolescent Report Of Helicopter Parenting: Examining Reporter Discrepancies And Associations With Adolescent Depression And Anxiety, Avneet Batra Jan 2023

Parent And Adolescent Report Of Helicopter Parenting: Examining Reporter Discrepancies And Associations With Adolescent Depression And Anxiety, Avneet Batra

Graduate Theses, Dissertations, and Problem Reports (ETD)

Research is replete with studies on Helicopter Parenting (HP) and its association with depression and anxiety (Cui et al., 2019; Schiffrin et al., 2014; 2019). However, most of the studies have focused on college students’ reports on helicopter parenting and there is relative dearth of studies with adolescents or with parents’ reports of HP (Pistella et al., 2020; Schiffrin et al., 2019). The current study aims to fill the gap in the literature by including both parent and adolescents’ perspectives on helicopter parenting, assess its unique association (parent and teens HP reports) with teen depression and anxiety both concurrently and …


The Relationship Between Maternal Emotion Socialization And Child Executive Functioning And Behavior: Exploring The Moderating Role Of Cortisol, Mayela Norwood Jan 2023

The Relationship Between Maternal Emotion Socialization And Child Executive Functioning And Behavior: Exploring The Moderating Role Of Cortisol, Mayela Norwood

CMC Senior Theses

In the early years of life, the development of children’s executive functioning (EF) and behavior regulation are critical to their later growth and self-sufficiency. Previous studies have indicated that one pathway by which children learn to regulate their emotions is through their immediate social environments (de Cock et al., 2017). Parents, in particular, play a significant role in the development of their children‘s emotion regulation and executive functioning (Fernandes et al., 2022). At the same time, physiological responses to stress also matter. Cortisol, the end product of the hypothalamic-pituitary-adrenal axis, has also been associated with children’s executive functioning and behavior …


How Do Cooperatives Enable Empowerment Among Rural Women? Evidence From The Municipality Of Cavinti, Laguna, Maria Theresa M. Castro-Bernardo, Liezel S. Cruz Dec 2022

How Do Cooperatives Enable Empowerment Among Rural Women? Evidence From The Municipality Of Cavinti, Laguna, Maria Theresa M. Castro-Bernardo, Liezel S. Cruz

Journal of Economics, Management and Agricultural Development

The persistent gender issues and their implications for sustainable development have led to several strategic yet collective schemes, such as the cooperatives, promising to contribute to (women) empowerment and social equality. Guided by Kabeer’s conceptual framework, this study analyzes the role of cooperative membership in promoting empowerment among its female coop-members in Cavinti, Laguna. Primary and secondary sources of data were used and analyzed using descriptive statistics and correlation analysis. The result indicates that cooperatives play a critical role in empowering women by providing new and/or improved knowledge and skills through capacity-building training necessary to make informed decisions, thus strengthening …


Pollution Emissions And Economic Growth In Asia Through The Lens Of The Environmental Kuznets Curve, Brian Jason H. Ponce, Yolanda T. Garcia, Gideon P. Carnaje, Agham C. Cuevas Dec 2022

Pollution Emissions And Economic Growth In Asia Through The Lens Of The Environmental Kuznets Curve, Brian Jason H. Ponce, Yolanda T. Garcia, Gideon P. Carnaje, Agham C. Cuevas

Journal of Economics, Management and Agricultural Development

The nonlinear relationship of pollution emissions with economic growth alongside energy consumption variables was examined to test the Environmental Kuznets Curve (EKC) hypothesis using a panel sample comprising 34 Asian economies from 2001 to 2013. Panel Autoregressive Distributed Lag models in the forms of Pooled Mean Group and Mean Group models were estimated and tested against one another using the Hausman test. For robustness checks, the same econometric techniques were applied to disaggregated panel groups based on income classifications. The study reveals that, while the EKC hypothesis holds in Asia, the findings were not robust across the disaggregated panel groups. …


Preferences Of Coffee Farmers For Attributes Of Selected Coffee Technologies In The Philippines, Jayson S. Cabral, Dia Noelle F. Velasco, Mar B. Cruz, Nohreen Ethel P. Manipol, Hannah D. Miranda-Quibot Dec 2022

Preferences Of Coffee Farmers For Attributes Of Selected Coffee Technologies In The Philippines, Jayson S. Cabral, Dia Noelle F. Velasco, Mar B. Cruz, Nohreen Ethel P. Manipol, Hannah D. Miranda-Quibot

Journal of Economics, Management and Agricultural Development

This paper looked into the preferences of 151 coffee farmers for the attributes of selected coffee technologies. The study was done to help guide technology developers in crafting post harvest processing facilities for coffee which their target market will need which can lead to a higher probability of commercialization of new coffee technologies. The study examined the preferences for attributes for coffee dryers, moisture meters, coffee depulpers, and coffee sorters using the Analytic Hierarchy Process (AHP) framework. The results revealed that the quality of the final product is the top priority for coffee farmers when choosing a coffee dryer. Non-destructiveness …


Market Analysis And Positioning Of Processed Halal Chevon Food Products, Jalaloden B. Marohom, Ivy Mar B. Cabornida Dec 2022

Market Analysis And Positioning Of Processed Halal Chevon Food Products, Jalaloden B. Marohom, Ivy Mar B. Cabornida

Journal of Economics, Management and Agricultural Development

Halal has gained popularity as a result of consumer concerns about food safety and ethical issues. Chevon is an important source of protein. However, no halal chevon products are commercially produced. Hence, the study aimed to develop positioning strategies to commercialize the products. A survey was undertaken of 400 potential consumers in the Philippines. The majority of the respondents were willing to buy halal food products. Descriptive statistics were applied, and findings revealed that products were generally acceptable. Potential consumers prefer it in wide assortment, in proper packaging, has informative labels, and easy to locate. However, their preference is significantly …


Ex-Ante Cost-Benefit Analysis Of High-End And Low-Cost Wireless Sensor Network (Wsn) Technology Packages For Efficient Irrigation Water Management In The Philippines, Marielle Q. Aringo, Victor B. Ella, Camille G. Martinez, Gamiello S. Pereira Dec 2022

Ex-Ante Cost-Benefit Analysis Of High-End And Low-Cost Wireless Sensor Network (Wsn) Technology Packages For Efficient Irrigation Water Management In The Philippines, Marielle Q. Aringo, Victor B. Ella, Camille G. Martinez, Gamiello S. Pereira

Journal of Economics, Management and Agricultural Development

Four wireless sensor network (WSN) technology packages developed for efficient irrigation water management in the Philippines were subjected to ex-ante cost-benefit analysis (CBA) to assess their financial viability. The WSN technologies include high-end and low-cost wireless sensors for upland crop production with drip irrigation system and lowland crop production with alternate wetting and drying (AWD). Results showed that the high-end WSN technology packages are only viable for high-value crops such as red onion, bell pepper, and hot pepper. The low-cost WSN technology packages are viable for all selected crops except sweet corn. Minimum areas were also generated for each crop …


Applying Data Science And Machine Learning To Understand Health Care Transition For Adolescents And Emerging Adults With Special Health Care Needs, Lisamarie Turk Dec 2022

Applying Data Science And Machine Learning To Understand Health Care Transition For Adolescents And Emerging Adults With Special Health Care Needs, Lisamarie Turk

Nursing ETDs

A problem of classification places adolescents and emerging adults with special health care needs among the most at risk for poor or life-threatening health outcomes. This preliminary proof-of-concept study was conducted to determine if phenotypes of health care transition (HCT) for this vulnerable population could be established. Such phenotypes could support development of future studies that require data classifications as input. Mining of electronic health record data and cluster analysis were implemented to identify phenotypes. Subsequently, a machine learning concept model was developed for predicting acute care and medical condition severity. Three clusters were identified and described (Cluster 1, n …


Religiosity And Organizational Citizenship Behavior (Ocb) In Supporting Community Engagement During The Covid-19 Pandemic: Work From Home (Wfh) And Work From Office (Wfo), Desprina Octaffiani, Evony Silvino Violita Dec 2022

Religiosity And Organizational Citizenship Behavior (Ocb) In Supporting Community Engagement During The Covid-19 Pandemic: Work From Home (Wfh) And Work From Office (Wfo), Desprina Octaffiani, Evony Silvino Violita

Journal of Environmental Science and Sustainable Development

Pandemic COVID-19 that is currently faced by all countries has changed the wheels of workers' lives in all sectors. Keeping work performance in good quality is needed to in improving company performance. One way that is considered important to maintain the performance of the workforce is by voluntary social support received from co-workers or what is called Organizational Citizenship Behaviour (OCB). This study examines the correlation o of job satisfaction and religiosity on OCB behaviour. Because while religious belief and the level of religiosity are an important part of a person's life, many studies have been conducted to test this., …


Advancing The Potential Of Pet And Pp-Based Beverage Packaging To Support Circular Economy, Dini Trisyanti, Khair Ranggi Laksita Wengi, Rizka Legita Rachmawati, Rangga Akib Dec 2022

Advancing The Potential Of Pet And Pp-Based Beverage Packaging To Support Circular Economy, Dini Trisyanti, Khair Ranggi Laksita Wengi, Rizka Legita Rachmawati, Rangga Akib

Journal of Environmental Science and Sustainable Development

With around 5.6 million tons of annual plastic consumption and merely 7 percent plastic recycling rate, Indonesia is facing a plastic pollution crisis. The recent progress of Indonesia’s recycling industries has provided an asset to address this crisis. In 2017, the domestic post-consumption plastic waste could only fulfil around 24 percent the domestic needs for recycled plastic, which stands at 1.65 million ton/year. Leveraging the plastic waste ‘asset’ through circular economy can fill this demand gap. A five-month study was conducted to analyse the recycling rate of Polyethylene terephthalate (PET) and Polypropylene (PP)-based beverage plastic packaging in Greater Jakarta Metropolitan …


Foreword From Handling Editor - 9th Edition, Ahyahudin Sodri Dec 2022

Foreword From Handling Editor - 9th Edition, Ahyahudin Sodri

Journal of Environmental Science and Sustainable Development

We are delighted to present the 9th edition of JESSD, published in December 2022. We have selected thirteen of the best articles for this edition that related with topic of Environmental Science and Sustainable Development.


Introduction, Anne Grauer Dec 2022

Introduction, Anne Grauer

Anthropology: Faculty Publications and Other Works

Paleopathology is a relatively new field that seeks to understand disease in the past. This chapter presents a brief history of the discipline and highlights the varied approaches adopted by contributors aligned with medical fields, anthropology and archaeology, and the biochemical sciences, to name a few. Advancements in methods and techniques, the contributions of technology, and the role that social theory plays in the development of hypotheses are discussed along with the importance of acknowledging and ameliorating critical ethical issues inherent to the field.


Risk Factors For Emergency Medical Care Or Hospitalization Due To Heat-Related Illness Or Injury: A Systematic Review, Blair Litwiller, Amber N. Barnes Dec 2022

Risk Factors For Emergency Medical Care Or Hospitalization Due To Heat-Related Illness Or Injury: A Systematic Review, Blair Litwiller, Amber N. Barnes

Florida Public Health Review

Background: Temperatures globally have been predicted to increase due to changes in the climate. As the earth gets warmer, it is expected that heat-related illness will also increase worldwide. An effective and appropriate public health response will be critical. Purpose: The aim of this review was to identify risk factors associated with heat-related illness and injury to provide target areas for future interventions. Methods: A review of existing literature was analyzed for risk factors that may increase the likelihood of being admitted to an emergency department for a heat related illness or injury. Results: Of the …


Natural Selection Of Immune And Metabolic Genes Associated With Health In Two Lowland Bolivian Populations, Amanda J. Lea, Angela Garcia, Jesusa Arevalo, Julien F. Ayroles, Kenneth Buetow, Steve W. Cole, Daniel Eid Rodriguez, Maguin Gutierrez, Heather M. Highland, Paul L. Hooper, Anne Justice, Thomas Kraft, Kari E. North, Jonathan Stieglitz, Hillard Kaplan, Benjamin C. Trumble, Michael Gurven Dec 2022

Natural Selection Of Immune And Metabolic Genes Associated With Health In Two Lowland Bolivian Populations, Amanda J. Lea, Angela Garcia, Jesusa Arevalo, Julien F. Ayroles, Kenneth Buetow, Steve W. Cole, Daniel Eid Rodriguez, Maguin Gutierrez, Heather M. Highland, Paul L. Hooper, Anne Justice, Thomas Kraft, Kari E. North, Jonathan Stieglitz, Hillard Kaplan, Benjamin C. Trumble, Michael Gurven

ESI Publications

A growing body of work has addressed human adaptations to diverse environments using genomic data, but few studies have connected putatively selected alleles to phenotypes, much less among underrepresented populations such as Amerindians. Studies of natural selection and genotype–phenotype relationships in underrepresented populations hold potential to uncover previously undescribed loci underlying evolutionarily and biomedically relevant traits. Here, we worked with the Tsimane and the Moseten, two Amerindian populations inhabiting the Bolivian lowlands. We focused most intensively on the Tsimane, because long-term anthropological work with this group has shown that they have a high burden of both macro and microparasites, as …


Exome Array Analysis Of 9721 Ischemic Stroke Cases From The Sign Consortium, Huichun Xu, Kevin Nguyen, Brady J Gaynor, Hua Ling, Wei Zhao, Patrick F Mcardle, Timothy D O'Connor, O Colin Stine, Kathleen A Ryan, Megan Lynch, Jennifer A Smith, Jessica D Faul, Yao Hu, Jeffrey W Haessler, Myriam Fornage, Charles Kooperberg, On Behalf Of The Trans-Omics For Precision Medicine Topmed Stroke Working Group, James A Perry, Charles C Hong, John W Cole, Elizabeth Pugh, Kimberly Doheny, Sharon L R Kardia, David R Weir, Steven J Kittner, Braxton D Mitchell, Sign Consortium Dec 2022

Exome Array Analysis Of 9721 Ischemic Stroke Cases From The Sign Consortium, Huichun Xu, Kevin Nguyen, Brady J Gaynor, Hua Ling, Wei Zhao, Patrick F Mcardle, Timothy D O'Connor, O Colin Stine, Kathleen A Ryan, Megan Lynch, Jennifer A Smith, Jessica D Faul, Yao Hu, Jeffrey W Haessler, Myriam Fornage, Charles Kooperberg, On Behalf Of The Trans-Omics For Precision Medicine Topmed Stroke Working Group, James A Perry, Charles C Hong, John W Cole, Elizabeth Pugh, Kimberly Doheny, Sharon L R Kardia, David R Weir, Steven J Kittner, Braxton D Mitchell, Sign Consortium

Faculty, Staff and Student Publications

Recent genome wide association studies have identified 89 common genetic variants robustly associated with ischemic stroke and primarily located in non-coding regions. To evaluate the contribution of coding variants, which are mostly rare, we performed an exome array analysis on 106,101 SNPs for 9721 ischemic stroke cases from the SiGN Consortium, and 12,345 subjects with no history of stroke from the Health Retirement Study and SiGN consortium. We identified 15 coding variants significantly associated with all ischemic stroke at array-wide threshold (i.e., p < 4.7 × 10-7), including two common SNPs in ABO that have previously been associated with stroke. Twelve of the remaining 13 variants were extremely rare …


Doctoral Studies As Learning To Rename The World, Hyleen Mariaye Dec 2022

Doctoral Studies As Learning To Rename The World, Hyleen Mariaye

Journal of Multicultural Affairs

The reflective experience documented in this paper engages with doctoral learning from Freire’s (1968/2000) conceptual lens of naming the world. Written from the narrative lens of the supervisor, it considers how doctoral level studies in education can position both the supervisor and the candidates as agents actively reconstructing their understanding of the world and their place in it. The doctoral journey is viewed as praxis compelling researchers to expand their frames for reading the world, accommodating the other, including multiple voices and thus demonstrating commitment to a global and yet constantly contested notion of citizenship.


Poetry And Praxis: Lessons From An Activist Educator, Dr. Emmanuel Tabi Dec 2022

Poetry And Praxis: Lessons From An Activist Educator, Dr. Emmanuel Tabi

Journal of Multicultural Affairs

Drawing on data from a narrative multi-case study based in Toronto, Canada, this article discusses the lived experiences of one Black activist. Utilizing critical race theory, new literacy studies and the rhetoric of cultural production as theoretical frameworks, the article foregrounds the work of Ebele, a Toronto activist whose work supported the educational trajectories and emotional well-being of Black students, many of whom reported being marginalized in school. Through his creative labor, Ebele directly addressed the sociology of anti-Black racism that deeply influences the lives of Afrodiasporic people in Canada. This article continues the conversation about what it means to …


Research Infrastructure Core Facilities At Research Centers In Minority Institutions: Part I-Research Resources Management, Operation, And Best Practices, Paul B Tchounwou, Mohamad Malouhi, Elizabeth O Ofili, Emma Fernández-Repollet, Daniel F Sarpong, Richard Yanagihara, Renato J Aguilera, Cecilia Ayón, Xiaoxin Chen, Asok Dasmahapatra, Song Gao, Cimona V Hinton, Robert Holt, Vladimir Kolesnichenko, Michael D Powell, Fatima Merchant, Kinfe K Redda, Abiel Roche-Lima, Cecilia M Shikuma, Jacqueline J Stevens, Jose A Torres, Robert T Trotter, James Wachira, Paul Wang, Kristen J Wells, Jason White, Yanyuan Wu Dec 2022

Research Infrastructure Core Facilities At Research Centers In Minority Institutions: Part I-Research Resources Management, Operation, And Best Practices, Paul B Tchounwou, Mohamad Malouhi, Elizabeth O Ofili, Emma Fernández-Repollet, Daniel F Sarpong, Richard Yanagihara, Renato J Aguilera, Cecilia Ayón, Xiaoxin Chen, Asok Dasmahapatra, Song Gao, Cimona V Hinton, Robert Holt, Vladimir Kolesnichenko, Michael D Powell, Fatima Merchant, Kinfe K Redda, Abiel Roche-Lima, Cecilia M Shikuma, Jacqueline J Stevens, Jose A Torres, Robert T Trotter, James Wachira, Paul Wang, Kristen J Wells, Jason White, Yanyuan Wu

Faculty, Staff and Student Publications

Funded by the National Institutes of Health (NIH), the Research Centers in Minority Institutions (RCMI) Program fosters the development and implementation of innovative research aimed at improving minority health and reducing or eliminating health disparities. Currently, there are 21 RCMI Specialized (U54) Centers that share the same framework, comprising four required core components, namely the Administrative, Research Infrastructure, Investigator Development, and Community Engagement Cores. The Research Infrastructure Core (RIC) is fundamentally important for biomedical and health disparities research as a critical function domain. This paper aims to assess the research resources and services provided and evaluate the best practices in …


Making Emotions Trustworthy, Xiaoyu Ke Dec 2022

Making Emotions Trustworthy, Xiaoyu Ke

Arts & Sciences Graduate Student Theses and Dissertations

I investigate ways by which agents can make their emotions more trustworthy from a perspective that’s informed by recent psychological research on the nature of emotion regulation. This dissertation is a collection of three articles, each addressing one type of cases of untrustworthy emotions in a particular context. Chapter one (Developing Appropriate Emotions) concerns emotions that are untrustworthy because they are irrelevant to the moral or epistemic judgements at hand. By situating the problem in the context of a situationist challenge to neo-Aristotelian virtue ethics, I argue that we can address this problem by developing ameliorative abilities such as emotion …


Tiam1-Mediated Synaptic Plasticity Underlies Comorbid Depression-Like And Ketamine Antidepressant-Like Actions In Chronic Pain, Qin Ru, Yungang Lu, Ali Bin Saifullah, Francisco A Blanco, Changqun Yao, Juan P Cata, De-Pei Li, Kimberley F Tolias, Lingyong Li Dec 2022

Tiam1-Mediated Synaptic Plasticity Underlies Comorbid Depression-Like And Ketamine Antidepressant-Like Actions In Chronic Pain, Qin Ru, Yungang Lu, Ali Bin Saifullah, Francisco A Blanco, Changqun Yao, Juan P Cata, De-Pei Li, Kimberley F Tolias, Lingyong Li

Faculty, Staff and Students Publications

Chronic pain often leads to depression, increasing patient suffering and worsening prognosis. While hyperactivity of the anterior cingulate cortex (ACC) appears to be critically involved, the molecular mechanisms underlying comorbid depressive symptoms in chronic pain remain elusive. T cell lymphoma invasion and metastasis 1 (Tiam1) is a Rac1 guanine nucleotide exchange factor (GEF) that promotes dendrite, spine, and synapse development during brain development. Here, we show that Tiam1 orchestrates synaptic structural and functional plasticity in ACC neurons via actin cytoskeleton reorganization and synaptic N-methyl-d-aspartate receptor (NMDAR) stabilization. This Tiam1-coordinated synaptic plasticity underpins ACC hyperactivity and drives chronic pain-induced depressive-like behaviors. …


Rural Movers Studies ... People Are Moving For Community Attributes And Jobs, Marilyn R. Schlake Dec 2022

Rural Movers Studies ... People Are Moving For Community Attributes And Jobs, Marilyn R. Schlake

Cornhusker Economics

University of Minnesota researchers conducted a Rural Movers Study to determine the motivations of people who moved within one to five years to rural Minnesota communities. Their findings are not unlike earlier research conducted at the University of Nebraska in 2008. The Rural Movers Study showed that 31 % of respondents moved due to a job or job offer. However, this was not one of the primary reasons individuals moved. For those individuals who did not move for employment, 76% wanted to find a good environment for raising their children, 67% moved to be closer to relatives, 64% looked for …


Potential Risks Inherent In Robotic Process Automation, Colin L. Robinson, David Y. Chan Dec 2022

Potential Risks Inherent In Robotic Process Automation, Colin L. Robinson, David Y. Chan

Journal of Vincentian Social Action

Robotic process automation (RPA) uses automation technologies to perform tasks typically performed by humans. Although such technology has been instrumental in expediting business operations and lowering costs, it has also created several risks that warrant scrutiny. When discussing the drawbacks of automation, many will point to the number of jobs lost to the influx of automation. However, there are technology risks that organizations must consider such as fraud and cybersecurity. Fraudsters may utilize RPA to commit more novel and subtle technological and cyber security fraud. Organizations may implement internal control measures to prevent or mitigate such schemes, segregation of duties, …


Consumer Boycotts In The Time Of War Crisis: An Efficient Citizenship Strategy Or A Temporary Spurt Of Solidarity, Jolanta Zralek Dec 2022

Consumer Boycotts In The Time Of War Crisis: An Efficient Citizenship Strategy Or A Temporary Spurt Of Solidarity, Jolanta Zralek

Journal of Vincentian Social Action

By drawing from the theory of consumer citizenship, collective activism, and consumer boycotts, this article strives to understand the nature of the current calls for consumer resistance and the following consumers’ actions that resulted from the Russian invasion of Ukraine. In particular, by utilizing Friedman’s (1991) taxonomy of boycotts, we aimed to identify the character, motives, and tools of ongoing boycotts and thus estimated their actual and probable effectiveness. The main research questions in this paper concern what type of consumer boycotts we currently observe, what the aims and motives are of current boycotting, and whether the noticed boycotting attempts …