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Full-Text Articles in Social and Behavioral Sciences

“It’S A No Brainer”: Ensuring Just Transitions In Iceland’S Fishing Industry, Olivia Bowers Apr 2024

“It’S A No Brainer”: Ensuring Just Transitions In Iceland’S Fishing Industry, Olivia Bowers

Independent Study Project (ISP) Collection

Iceland’s government intends to achieve carbon neutrality by 2040, aiming to target various economic sectors and industries for increased renewable-energy usage. One of its most important plans revolves renewable-energy usage in the fishing industry, which accounts for almost 12% of the country’s GHG emissions. This study aims to understand the perspectives of different stakeholders concerning renewable energy in the fishing industry, using these opinions and existing literature to provide recommendations for a just, equitable, and achievable energy transition. Additionally, this study particularly focuses on the opinions of actors in Vestmannaeyjar, an island community of 4,300 with an especially vibrant, significant, …


Género Y Resiliencia En La Amazonía Peruana: Las Experiencias Y Respuestas De Agricultoras Indígenas Ante El Cambio Climático, Zoe Klausner Apr 2024

Género Y Resiliencia En La Amazonía Peruana: Las Experiencias Y Respuestas De Agricultoras Indígenas Ante El Cambio Climático, Zoe Klausner

Independent Study Project (ISP) Collection

El cambio climático antropogénico está redefiniendo rápidamente las relaciones humano-ambientales, especialmente en la Amazonía peruana, donde más de 66 comunidades indígenas enfrentan mayores sequías y temperaturas, afectando profundamente sus medios de vida. Crucialmente, desde la visión ecofeminista central a esta investigación se subraya que las mujeres indígenas experimentan los impactos del cambio climático más severamente y son a menudo los líderes en el fomento de la resiliencia ambiental. Esta investigación explora cómo las agricultoras indígenas de la Amazonía peruana viven el cambio climático y sus estrategias de adaptación y resiliencia. El trabajo de campo se realizó en la comunidad Ese'Eja …


The Impact Of The Gut-Brain Axis On Alzheimer’S Disease, Elissa Wakim Mar 2024

The Impact Of The Gut-Brain Axis On Alzheimer’S Disease, Elissa Wakim

Best Integrated Writing

Elissa’s review for the Graduate Biomedical Review focuses on the links between the gastrointestinal tract and the brain; the gut-brain axis and the development of Alzheimer’s disease. As a student in the Microbiology and Immunology Masters Program Elissa was particularly interested in the gut microbiota and their connection to neurodegenerative disease. She tidily reviewed the literature and wrote a fascinating and compelling piece of work.


Best Integrated Writing Spring 2024 - Complete Edition, Wright State University School Of Humanities And Cultural Studies, Kristie Mckiernan, Tracy Smith Mar 2024

Best Integrated Writing Spring 2024 - Complete Edition, Wright State University School Of Humanities And Cultural Studies, Kristie Mckiernan, Tracy Smith

Best Integrated Writing

Best Integrated Writing includes excellent student writing from Integrated Writing courses taught at Wright State University. This is the first issue after a 5 year hiatus.


Attitudes And Self-Efficacy Of Swimming Coaches Towards The Inclusion Of Swimmers With Autism Spectrum Disorder, Eleftheria Kasagianni, Dimitrios Kokaridas, Panagiotis Varsamis, Vasilis Tsimaras Mar 2024

Attitudes And Self-Efficacy Of Swimming Coaches Towards The Inclusion Of Swimmers With Autism Spectrum Disorder, Eleftheria Kasagianni, Dimitrios Kokaridas, Panagiotis Varsamis, Vasilis Tsimaras

International Journal of Aquatic Research and Education

The purpose of this study was to investigate the attitudes and self-efficacy of swimming coaches regarding the inclusion of swimmers with autism spectrum disorder (ASD). The sample consisted of 150 Greek swimming coaches with an average age of 29.58 years. Each participant completed the Swimming Coaches Attitudes towards Inclusion Questionnaire for perceptions assessment and the Biddle and Goudas (1997) self-efficacy questionnaire. The statistical analysis used SPSS 27 to calculate Cronbach’s alpha, Pearson product-moment correlations, independent t-tests, and ANOVA. The findings of the study showed that the swimming coaches expressed positive attitudes and a high percentage of perceived self-efficacy towards the …


In This Issue 14:3, Stephen J. Langendorfer Ph.D. Mar 2024

In This Issue 14:3, Stephen J. Langendorfer Ph.D.

International Journal of Aquatic Research and Education

In This Issue 14:3


A Research Framework To Improve Evidence-Based Practice Surrounding The Resuscitation Response To Drowning In Surf Lifesaving, Elissa Hooper, Aaron T. Scanlan, Shayne D. Baker, Samantha Fien Mar 2024

A Research Framework To Improve Evidence-Based Practice Surrounding The Resuscitation Response To Drowning In Surf Lifesaving, Elissa Hooper, Aaron T. Scanlan, Shayne D. Baker, Samantha Fien

International Journal of Aquatic Research and Education

Surf lifesaving members are essential first responders who patrol public waterways, performing rescues and resuscitation to individuals in the community when needed. In this way, surf lifesaving members experience arduous physical requirements alongside extensive psychological stress during resuscitation. Surf Life Saving Queensland (SLSQ) represents the predominant, frontline lifesaving service in Queensland, Australia; however, little research has explored key aspects of drowning resuscitations involving this organisation, as well as in the broader lifesaving industry, limiting our current understanding on this vital topic. We sought to explore key aspects of drowning resuscitations within SLSQ and create a framework to generate evidence-based practice. …


‘You Have To Respect The Water’: Participant Experiences Of Appreciating And Managing The Risks Associated With Open Water Swimming – A Rapid Ethnographic Study, Mark A. Christie, David Elliott Mar 2024

‘You Have To Respect The Water’: Participant Experiences Of Appreciating And Managing The Risks Associated With Open Water Swimming – A Rapid Ethnographic Study, Mark A. Christie, David Elliott

International Journal of Aquatic Research and Education

Open water swimming (OWS) has rapidly grown in popularity, driven by the purported health benefits of cold-water immersion. A paucity of research remains specifically considering the notable risks inherent in OWS participation, and a lack of qualitative research on freshwater swimming experiences, and safety-related issues therein. This rapid ethnographic study, based at a dedicated OWS lake in the UK, conducted semi-structured interviews with OWS participants (n=17; female=11, male=6). Two core themes emerged: environmental issues impacting OWS experiences and behaviours; and knowledge and education of OWS which highlighted safe/unsafe practices, levels of education for managing risks, personal preparedness, swimming solo/with others, …


Lay Rescuer Equipment Preferences And Efficacy During A Simulated Drowning Event, Alison M. Miller, William D. Ramos, Kristina R. Anderson, Jill Cuvala Mar 2024

Lay Rescuer Equipment Preferences And Efficacy During A Simulated Drowning Event, Alison M. Miller, William D. Ramos, Kristina R. Anderson, Jill Cuvala

International Journal of Aquatic Research and Education

During a drowning incident where a lifeguard is not present, a bystander – referred to as a lay rescuer - may put themselves in danger by attempting a rescue. When lay rescuers can avoid entering the water by using rescue equipment to help a drowning victim, it serves to not only help the person actively drowning, but also provides a layer of protection to a lay rescuer. This study sought to examine the following questions: (a) which pieces of rescue equipment were preferred by lay rescuers at pre-determined short and long distances, (b) do lay rescuers select appropriate rescue equipment …


Barriers: Location, Functionality, And Method Of Access In Childhood Pool/Spa Submersion Incidents, United States, 2000-2017, Alison Miller, Kristina R. Anderson, William D. Ramos Mar 2024

Barriers: Location, Functionality, And Method Of Access In Childhood Pool/Spa Submersion Incidents, United States, 2000-2017, Alison Miller, Kristina R. Anderson, William D. Ramos

International Journal of Aquatic Research and Education

Drowning is a leading cause of fatality among children in the United States, and residential pools/spas currently account for as much as 80% of these submersion incidents. This study reviewed narrative case reports obtained from the United States Consumer Product Safety Commission (CPSC) to understand barrier location, type, and functionality as methods of pool/spa access for childhood submersion incidents. Retroactive analysis of 1,523 fatal and non-fatal submersion incidents among children aged 13 years old and younger was conducted using the CPSC in depth investigation dataset from 2000-2017. Narrative descriptions were coded according to the attributes of barrier location, functionality, and …


Perceived And Real Water Competency And Drowning Risk Among Adults, Teresa Stanley, Kevin Moran, Dawn Garbett, Alan Ovens Mar 2024

Perceived And Real Water Competency And Drowning Risk Among Adults, Teresa Stanley, Kevin Moran, Dawn Garbett, Alan Ovens

International Journal of Aquatic Research and Education

Traditionally, public understanding of drowning survival has focused on swimming capacity, often measured by how far a person can swim. With respect to the high incidence of adult drowning in high-income countries, using the more inclusive concept of water competency may yield a more comprehensive explanatory framework for understanding the reasons behind these drownings. Any competency base required to survive a drowning situation is dynamic, complex, and multi-faceted. Furthermore, perceptions of risk and capacity to cope with that risk are likely to be pivotal to the avoidance of drowning. Adults’ perceived water competence was measured against their actual water competence …


The Significance Of Using Digital Story-Telling For Enhancing English Oral Communication Skills Among Media Students At Al- Quds Open University, Murad A. Ahmed Tamimi Mar 2024

The Significance Of Using Digital Story-Telling For Enhancing English Oral Communication Skills Among Media Students At Al- Quds Open University, Murad A. Ahmed Tamimi

Middle East Journal of Communication Studies

Due to issues including uninspired teaching techniques and language anxiety, students at Al-Quds Open University, particularly those enrolled in the media major, experience difficulties in establishing strong oral communication skills in a multicultural context. A potential remedy is digital story-telling, which uses multimedia to craft captivating stories that appeal to students who are accustomed to using digital devices. This study evaluated how digital story-telling improved media students' spoken English communication abilities in the second semester of the 2023–2024 academic year. Incorporating motifs from the current Tufan al-Aqsa conflict, the study sought to offer stimulating and culturally appropriate educational opportunities. Twenty-seven …


Interest In An Instagram-Delivered Gestational Weight Gain Intervention Among Pregnant Women With Pre-Pregnancy Overweight Or Obesity, Molly E. Waring, Danielle Arigo, Lauren R. Rudin, Sherry L. Pogoto, Tiffany A. Moore Simas, Alexa B. Horkachuck Mar 2024

Interest In An Instagram-Delivered Gestational Weight Gain Intervention Among Pregnant Women With Pre-Pregnancy Overweight Or Obesity, Molly E. Waring, Danielle Arigo, Lauren R. Rudin, Sherry L. Pogoto, Tiffany A. Moore Simas, Alexa B. Horkachuck

College of Science & Mathematics Departmental Research

Background: Barriers to attending in-person lifestyle interventions are common during pregnancy. The majority of young adults use Instagram, and pregnancy-related content abounds on this social media platform. The aims of this study were to assess interest in an Instagram-delivered gestational weight gain (GWG) intervention, examine characteristics associated with program interest, describe interest in specific program components, and to explore perceived advantages of and concerns about the proposed intervention. Methods: English-speaking pregnant women with pre-pregnancy overweight or obesity in the US who use Instagram completed a cross-sectional online survey (N=229). Participants reported interest in a proposed Instagram-delivered GWG intervention (very/quite a …


Antitumor Efficacy And Safety Of Unedited Autologous Cd5car T Cells In Relapsed/Refractory Mature T-Cell Lymphomas, Laquisa C Hill, Rayne H Rouce, Mengfen J Wu, Tao Wang, Royce Ma, Huimin Zhang, Birju Mehta, Natalia Lapteva, Zhuyong Mei, Tyler S Smith, Lina Yang, Madhuwanti Srinivasan, Phillip M Burkhardt, Carlos A Ramos, Premal Lulla, Martha Arredondo, Bambi Grilley, Helen E Heslop, Malcolm K Brenner, Maksim Mamonkin Mar 2024

Antitumor Efficacy And Safety Of Unedited Autologous Cd5car T Cells In Relapsed/Refractory Mature T-Cell Lymphomas, Laquisa C Hill, Rayne H Rouce, Mengfen J Wu, Tao Wang, Royce Ma, Huimin Zhang, Birju Mehta, Natalia Lapteva, Zhuyong Mei, Tyler S Smith, Lina Yang, Madhuwanti Srinivasan, Phillip M Burkhardt, Carlos A Ramos, Premal Lulla, Martha Arredondo, Bambi Grilley, Helen E Heslop, Malcolm K Brenner, Maksim Mamonkin

Center for Medical Ethics and Health Policy Staff Publications

Despite newer targeted therapies, patients with primary refractory or relapsed (r/r) T-cell lymphoma have a poor prognosis. The development of chimeric antigen receptor (CAR) T-cell platforms to treat T-cell malignancies often requires additional gene modifications to overcome fratricide because of shared T-cell antigens on normal and malignant T cells. We developed a CD5-directed CAR that produces minimal fratricide by downmodulating CD5 protein levels in transduced T cells while retaining strong cytotoxicity against CD5+ malignant cells. In our first-in-human phase 1 study (NCT0308190), second-generation autologous CD5.CAR T cells were manufactured from patients with r/r T-cell malignancies. Here, we report safety …


Nebraska Women In Agriculture Conference Marks 39 Years, Ryan Evans, Sarah Treffer, Jessica Groskopf Mar 2024

Nebraska Women In Agriculture Conference Marks 39 Years, Ryan Evans, Sarah Treffer, Jessica Groskopf

Cornhusker Economics

The Nebraska Women in Agriculture program marked 39 years of educating and empowering females in farming, ranching, and agribusiness, with nearly 380 people attending its annual conference on February 22 and 23, 2024 in Kearney, Nebraska, with a pre-conference session held on February 21. Including 25 workshops, 5 keynotes, and activities to help learn about risk management, farm and ranch improvement, and successful business practices.


Vigilance And Foraging Behaviors Of Two Sciurid Species Between College Campuses And Urban Environments, Patrick Geyer, Zoe Buffington, Lorelei E. Patrick Mar 2024

Vigilance And Foraging Behaviors Of Two Sciurid Species Between College Campuses And Urban Environments, Patrick Geyer, Zoe Buffington, Lorelei E. Patrick

SACAD: Scholarly Activities

A comparison between the extent that sciurid specimens display vigilance and foraging behaviors on college campuses against specimens within urban environments. Observations of fox squirrels and western gray squirrels were taken from the Squirrel-Net behavioral database used for this project. We found there was a significant difference between the percent vigilance behaviors and foraging behaviors on college campuses compared to urban environments. This suggests that squirrels residing on college campuses are more desensitized to pedestrian activity and foot traffic compared to squirrels that inhabit urban areas.


Evaluating Drowning Prevention Campaigns - The Challenge Of Getting The Right Information To The Right People At The Right Time: A Response To Calverley, Petrass, And Blitvich, Gemma Crawford, Meg Abercromby, Malena Della Bona, Justine E. Leavy Ph.D. Mar 2024

Evaluating Drowning Prevention Campaigns - The Challenge Of Getting The Right Information To The Right People At The Right Time: A Response To Calverley, Petrass, And Blitvich, Gemma Crawford, Meg Abercromby, Malena Della Bona, Justine E. Leavy Ph.D.

International Journal of Aquatic Research and Education

Evidence-informed decision making requires timely and readily available research and evaluation for policy and practice. In the context of drowning prevention, evaluation of interventions in the grey and peer reviewed literature is relatively scarce. Lack of evidence and associated barriers to access limits the scope of knowledge translation efforts and the application of research outcomes to initiatives designed to prevent drowning. The paper, Alcohol Focused Drowning Prevention Campaigns: What Do We Know and What Should We Do Now? highlights a lack of specific evaluation for alcohol-focused drowning prevention campaigns. We offer insights as evaluators of a youth water safety program …


03.25.2024 Orsp Connect, Liz Williamson Mar 2024

03.25.2024 Orsp Connect, Liz Williamson

ORED Newsletter

Cammi Thornton, Compliance Training Requirements


Coomassie Brilliant Blue Dye As A Method For Analyzing Fracture Markings In Bone, Abigail Hoffmeister, David Harutunyan, Matthew Aizawa, Everett Baker, Brandon Mendoza, Chase Freeman, Siran Iskanian Mar 2024

Coomassie Brilliant Blue Dye As A Method For Analyzing Fracture Markings In Bone, Abigail Hoffmeister, David Harutunyan, Matthew Aizawa, Everett Baker, Brandon Mendoza, Chase Freeman, Siran Iskanian

Seaver College Research And Scholarly Achievement Symposium

Coomassie Brilliant Blue Dye is a dye commonly used to stain proteins. Because of its ability to adhere to proteins, this research has focused on perfecting a method of dyeing a fractured flat bone in order to most accurately observe and analyze fracture markings within the trabecular layer. Stereoscopic microscopy was the chosen technique of analysis for this research because of its proven effectiveness in glass and ceramic fractography to observe varying depths. In order to most effectively apply stereoscopic microscopy to this research, the following variables were manipulated to maximize color contrast in the trabecular layer in order to …


Materials And Methods Developed For The Recording And Analysis Of Behavior In The Common Marmoset (Callithrix Jacchus)., Christian Wintle Mar 2024

Materials And Methods Developed For The Recording And Analysis Of Behavior In The Common Marmoset (Callithrix Jacchus)., Christian Wintle

UNO Student Research and Creative Activity Fair

Materials and methods developed for the recording and analysis of behavior in the common marmoset (Callithrix jacchus).

Christian J. Wintlea, Jordan B. Hernandeza,b,c, Dobromir Dotovd, and Jonathan B. Claytona,b,e,f,g

aDepartment of Biology, University of Nebraska at Omaha, Omaha, NE, USA

bNebraska Food for Health Center, University of Nebraska-Lincoln, Lincoln, NE, USA

cDepartment of Genetics, Cell Biology, and Anatomy, University of Nebraska Medical Center, NE, USA

dDepartment of Biomechanics, University of Nebraska at Omaha, Omaha, NE, USA

eDepartment of Food Science and Technology, University of Nebraska-Lincoln, Lincoln, …


Investigating Interrater-Reliability In Assessing Social Behavior Of Monodelphis Domestica, Bianca A. Camacho, Johanna Perez, Jatziry L. Escobedo, John L. Vandeberg, Mario Gil Mar 2024

Investigating Interrater-Reliability In Assessing Social Behavior Of Monodelphis Domestica, Bianca A. Camacho, Johanna Perez, Jatziry L. Escobedo, John L. Vandeberg, Mario Gil

Research Symposium

Background: Reliable, consistent, and objective data is a goal all studies aim to achieve, but many struggle to obtain when subjective biases between researchers can occur. Inter-rater reliability (IRR) is a statistical measure used to quantify the degree of agreement between researchers qualitatively scoring the same phenomenon. The primary goal of this study is to enhance the methodology used to achieve optimal IRR. Using an established ethogram, our team of researchers scored the social behavior of the adult gray short-tailed opossum (Monodelphis domestica) to propose an effective method for achieving high IRR that can contribute to future …


Case Studies On Biomedical Innovation Systems In Major Countries, Xiaoling Ma Mar 2024

Case Studies On Biomedical Innovation Systems In Major Countries, Xiaoling Ma

Bulletin of Chinese Academy of Sciences (Chinese Version)

The study focuses on the basic research, technological breakthroughs, transformation and commercialization of representative biomedical innovations over the past century—including penicillin, artemisinin, monoclonal antibodies, tumor immunotherapy, adenoviral gene therapy, mRNA vaccines, CRISPR/Cas9 gene editing, etc.—adopting a “dissecting the sparrow” case study methodology to conduct in-depth analyses (“double-clicking”) of each breakthrough, thereby mapping the institutional architectures and performance outcomes of national biomedical innovation systems and achieving a “seeing both trees and forest” perspective. Through comparative analysis, it reveals that the United States, compared with the United Kingdom, Japan, Germany and China, has developed a smooth technology transfer system and a mature …


Developing New Agricultural Productivity And Empowering High-Quality Agricultural Development, Yafei Yan, Junhui Cui Mar 2024

Developing New Agricultural Productivity And Empowering High-Quality Agricultural Development, Yafei Yan, Junhui Cui

Bulletin of Chinese Academy of Sciences (Chinese Version)

New quality productivity represents an advanced form of productivity, and it plays a leading role in innovation. The acceleration of new agricultural productivity formation and development is essential for fostering high-quality agricultural growth in China. However, there are also several challenges, such as limited natural resources, technological bottlenecks, shortage of agricultural professionals, outdated production methods, and imperfect systems and mechanisms. This study suggests that strengthening the protection of the ecological “trinity” of cultivated land quantity and quality to ensure food security; accelerating the development of agricultural technological innovation to enhance industry efficiency; innovating agricultural production methods to promote the green …


A Fork In The Road: Uncovering The Impact Of Industrial Animal Agriculture On The Physical Health Of Communities Of Color, Mariana Zepeda Mar 2024

A Fork In The Road: Uncovering The Impact Of Industrial Animal Agriculture On The Physical Health Of Communities Of Color, Mariana Zepeda

Population Health Research Brief Series

Nearly all (99%) farmed animals in the U.S. come from Concentrated Animal Feeding Operations (CAFOs). CAFOs are industrial agriculture facilities defined by the U.S. Environmental Protection Agency (EPA) as operations where animals are raised in confinement and meet animal size and waste material thresholds. Communities located near CAFOs, which tend to have high shares of low-income and racial/ethnic minority residents, are at risk of exposure to CAFO-related air and water pollutants. This brief summarizes the health risks for communities located near CAFOs. Additionally, it calls for government regulations that improve transparency, management, and consumer empowerment.


03.18.2024 Orsp Connect, Liz Williamson Mar 2024

03.18.2024 Orsp Connect, Liz Williamson

ORED Newsletter

SPAN and ARC form training, Nature Masterclasses, Glisto Rice, Useful Links


The Digital Transition: Are Adults Aged 65 Years Or Older Willing To Complete Online Forms And Questionnaires In Patient Portals?, Nancy P Gordon, Sherry Zhang, Joan C Lo, Christina F Li Mar 2024

The Digital Transition: Are Adults Aged 65 Years Or Older Willing To Complete Online Forms And Questionnaires In Patient Portals?, Nancy P Gordon, Sherry Zhang, Joan C Lo, Christina F Li

Faculty, Staff and Student Publications

INTRODUCTION: Patients are being encouraged to complete forms electronically using patient portals rather than on paper, but willingness of older adults to make this transition is uncertain.

METHODS: The authors analyzed data for 4105 Kaiser Permanente Northern California 2020 Member Health Survey respondents aged 65-85 years who answered a question about willingness to complete online forms and questionnaires using a patient portal. Data weighted to the Kaiser Permanente Northern California membership were used to estimate percentages of older adults willing to complete patient portal forms and questionnaires. Chi-square tests and log-Poisson regression models that included sociodemographic, internet use, and patient …


A Nutritional Intervention To Improve Body Composition In Adolescent Athletes, Michael Ryan, Rosemary E. Borgerding, Kimberly L. Oliver Mar 2024

A Nutritional Intervention To Improve Body Composition In Adolescent Athletes, Michael Ryan, Rosemary E. Borgerding, Kimberly L. Oliver

Journal of Athlete Development and Experience

This study assessed the effectiveness of a sports nutrition intervention designed to improve body composition in 25 high-school male athletes over a 12-week period. Employing a mixed-methods approach within a quasi-experimental one-group pretest-posttest design, the intervention integrated nutrition education with the provision of food. Quantitative results revealed significant reductions in body fat percentage and fat mass, and an increase in fat-free mass. Qualitative insights highlighted the untapped nutritional potential of adolescents and emphasized the importance of accessibility and simplicity in driving compliance. The findings suggest that targeted nutritional interventions can positively impact adolescent athletes' body composition. The study underscores the …


An Exposome Atlas Of Serum Reveals The Risk Of Chronic Diseases In The Chinese Population, Lei You, Jing Kou, Mengdie Wang, Guoqin Ji, Xiang Li, Chang Su, Fujian Zheng, Mingye Zhang, Yuting Wang, Tiantian Chen, Ting Li, Lina Zhou, Xianzhe Shi, Chunxia Zhao, Xinyu Liu, Surong Mei, Guowang Xu Mar 2024

An Exposome Atlas Of Serum Reveals The Risk Of Chronic Diseases In The Chinese Population, Lei You, Jing Kou, Mengdie Wang, Guoqin Ji, Xiang Li, Chang Su, Fujian Zheng, Mingye Zhang, Yuting Wang, Tiantian Chen, Ting Li, Lina Zhou, Xianzhe Shi, Chunxia Zhao, Xinyu Liu, Surong Mei, Guowang Xu

Faculty, Staff and Student Publications

Although adverse environmental exposures are considered a major cause of chronic diseases, current studies provide limited information on real-world chemical exposures and related risks. For this study, we collected serum samples from 5696 healthy people and patients, including those with 12 chronic diseases, in China and completed serum biomonitoring including 267 chemicals via gas and liquid chromatography-tandem mass spectrometry. Seventy-four highly frequently detected exposures were used for exposure characterization and risk analysis. The results show that region is the most critical factor influencing human exposure levels, followed by age. Organochlorine pesticides and perfluoroalkyl substances are associated with multiple chronic diseases, …


03.11.2024 Orsp Connect, Liz Williamson Mar 2024

03.11.2024 Orsp Connect, Liz Williamson

ORED Newsletter

PAPPG Updates, J. R. Love, William Magee Institute grant


Role Of Glia In Diurnal Rhythms In Neuroinflammation And Blood-Brain Barrier Breakdown, Jennifer Hoi-Ping Lawrence Mar 2024

Role Of Glia In Diurnal Rhythms In Neuroinflammation And Blood-Brain Barrier Breakdown, Jennifer Hoi-Ping Lawrence

Arts & Sciences Graduate Student Theses and Dissertations

While inflammation is an important mechanism for the return to homeostasis post insult or injury, inflammation in the central nervous system (CNS) can lead to irreparable damage. To mitigate this process, the brain is protected from circulating neurotoxic molecules as well as peripheral immune cells through the tightly regulated blood-brain barrier (BBB). The balance between pro- and anti- inflammation in the CNS rapidly shifts towards a neurotoxic proinflammatory state during acute bacterial or viral infections or chronic neuroinflammatory diseases. Excessive inflammatory responses are also coupled with extensive BBB leakage and breakdown, allowing rampant entry of peripheral inflammatory cells and mediators …