Social and Behavioral Sciences Commons^™

From Traumatic Brain Injury To Posttraumatic Epilepsy: What Animal Models Tell Us About The Process And Treatment Options, Asla Pitkänen, Riikka J. Immonen, Olli H.J. Gröhn, Irina Kharatishvili

Biomedicine and Animal Models in Research Collection

A large number of animal models of traumatic brain injury (TBI) are already available for studies on mechanisms and experimental treatments of TBI. Immediate and early seizures have been described in many of these models with focal or mixed type (both gray and white matter damage) injury. Recent long-term video-electroencephalography (EEG) monitoring studies have demonstrated that TBI produced by lateral fluid-percussion injury in rats results in the development of late seizures, that is, epilepsy. These animals develop hippocampal alterations that are well described in status epilepticus–induced spontaneous seizure models and human posttraumatic epilepsy (PTE). In addition, these rats have damage …

Computing For Human Experience: Sensors, Perception, Semantics, Web N.0, And Beyond, Amit P. Sheth

Kno.e.sis Publications

Traditionally there has been a strong separation between computing and human activities in the real world. The approach has largely been that of mapping the complexity and richness of the real world to constrained computer models and languages for more efficient computation, and then transferring the results for use in the real world. I think the time is ripe to reverse the situation, for computing and communication to transparently enrich and enhance human experience. Today, devices enable something more than a 'human instructs machine' paradigm. We are seeing computing and communication engage transparently in human activities by enriching them in …

Temperature Influence And Heat Management Requirements Of Microalgae Cultivation In Photobioreactors, Thomas Hagen Mehlitz

Master's Theses

Microalgae are considered one of the most promising feedstocks for biofuel production for the future. The most efficient way to produce vast amounts of algal biomass is the use of closed tubular photobioreactors (PBR). The heat requirement for a given system is a major concern since the best algae growth rates are obtained between 25-30 °C, depending on the specific strain. A procedure to determine temperature influence on algal growth rates was developed for a lab-scale PBR system using the species Chlorella. A maximum growth rate of 1.44 doublings per day at 29 °C (optimal temperature) was determined. In addition, …

Human Predators Outpace Other Agents Of Trait Change In The Wild, Chris T. Darimont, Stephanie M. Carlson, Michael T. Kinnison, Paul C. Paquet, Thomas E. Reimchen, Christopher C. Wilmers

Nonindigenous Pests and Biological Invasions Collection

The observable traits of wild populations are continually shaped and reshaped by the environment and numerous agents of natural selection, including predators. In stark contrast with most predators, humans now typically exploit high proportions of prey populations and target large, reproductive-aged adults. Consequently, organisms subject to consistent and strong ‘harvest selection’ by fishers, hunters, and plant harvesters may be expected to show particularly rapid and dramatic changes in phenotype. However, a comparison of the rate at which phenotypic changes in exploited taxa occurs relative to other systems has never been undertaken. Here, we show that average phenotypic changes in 40 …

Why Gujarat Needs Much Better Higher Education & Research To Succeed In Knowledge Economy & What We Can Do About It?, Amit P. Sheth, Kamlesh Lulla, Sanjay Chaudhary

Kno.e.sis Publications

This white paper distills the deliberations on the role of higher education and research as a key enabler of a Knowledge based Society. In particular it discusses (a) the importance of higher quality PhDs for building a knowledge society, (b) the initiatives and progress in competing economies in higher education and research, (c) where Gujarat stands in comparison, and (d) some recommendations on what Gujarat can do to enable timely progress towards building a knowledge based society and economy. These deliberations were conducted in conjunction with the International Conference on 'Reconnecting Gujarati Diaspora with its Homeland: Contribution to its Development …

The Effects Of The Acetic Acid “Pain” Test On Feeding, Swimming, And Respiratory Responses Of Rainbow Trout (Oncorhynchus Mykiss): A Critique On Newby And Stevens (2008), Lynne U. Sneddon

Experimentation Collection

Newby and Stevens’ (2008) paper ‘‘The effects of the acetic acid ‘pain’ test on feeding, swimming, and respiratory responses of rainbow trout (Oncorhynchus mykiss)’’ examines the effects of a noxious stimulus on the behaviour of trout in an attempt to replicate research conducted in my laboratory (Sneddon, 2003a; Sneddon, 2007; Sneddon et al., 2003a,b; Reilly et al., 2008). However, the authors used a different protocol to the one already published and I would like to respond to some of their points of discussion to provide scientific explanations for their results using data from my laboratory. The authors show that swimming …

Quantitative And Qualitative Assessment Of The Response Of Foals To The Presence Of An Unfamiliar Human, Michela Minero, Maria Vittoria Tosi, Elisabetta Canali, Françoise Wemelsfelder

Sentience Collection

This work aimed to apply a combined qualitative and quantitative approach to the interpretation of an on-farm behaviour test for horses, and to examine whether 1 month of handling would affect the response of yearlings to an unfamiliar stationary human in their home environment. Throughout a 1-month period, 14 Thoroughbred Yearlings (16 ± 0.22 months old) that had formerly experienced minimal contact with humans, were handled daily for about 45 min. The yearlings were tested twice, just before and just after the handling period. The behaviour of the horses during the tests was both video-recorded and directly recorded by the …

Are Animal Models Predictive For Humans?, Niall Shanks, Ray Greek, Jean Greek

Validation of Animal Experimentation Collection

It is one of the central aims of the philosophy of science to elucidate the meanings of scientific terms and also to think critically about their application. The focus of this essay is the scientific term predict and whether there is credible evidence that animal models, especially in toxicology and pathophysiology, can be used to predict human outcomes. Whether animals can be used to predict human response to drugs and other chemicals is apparently a contentious issue. However, when one empirically analyzes animal models using scientific tools they fall far short of being able to predict human responses. This is …

Reintroduction Of The Chinese Tiger, Philip J. Nyhus, Urs Breitenmoser, Ron Tilson

Faculty Scholarship

No abstract provided.

Genetic And Environmental Contributions To Body Mass Index: Comparative Analysis Of Monozygotic Twins, Dizygotic Twins And Same-Age Unrelated Siblings, Nancy Segal, R. Feng, Shirley Mcguire, D. Allison, S. Miller

Psychology

Background—Earlier studies have established that a substantial percentage of variance in obesity-related phenotypes is explained by genetic components. However, only one study has used both virtual twins (VTs) and biological twins and was able to simultaneously estimate additive genetic, non-additive genetic, shared environmental and unshared environmental components in body mass index (BMI). Our current goal was to re-estimate four components of variance in BMI, applying a more rigorous model to biological and virtual multiples with additional data. Virtual multiples share the same family environment, offering unique opportunities to estimate common environmental influence on phenotypes that cannot be separated from …

Atlas Of Sorghum (Sorghum Bicolor (L.) Moench): Production In Eastern And Southern Africa, Charles S. Wortmann, Martha Mamo, Christopher Mburu, Elias Letayo, Girma Abebe, Kaizzi C. Kayuki, Medson Chisi, Munyaradzi Mativavarira, Soares Xerinda, Theophile Ndacyayisenga

INTSORMIL Scientific Publications

Grain sorghum (Sorghum bicolor (L.) Moench) is a major crop in many parts of Africa and is noted for its versatility and diversity. It is adapted over a wide range of precipitation and temperature levels and is produced at sea level to above 2000 m altitude. In eastern and southern Africa, it is primarily a crop of resource-poor, small-scale farmers and is typically produced under adverse conditions such as low input use and marginal lands. There are numerous biotic and abiotic constraints to production. The grain and stover are used in many different ways with localized preferences. Much information …

An Undescribed Gecko (Gekkonidae: Cyrtodactylus) From Deer Cave, Gunung Mulu National Park, Sarawak, With Comments On The Distribution Of Bornean Cave Geckos, Donald A. Mcfarlane, Joyce Lundberg, Keith Christenson

WM Keck Science Faculty Papers

Geckos of the genus Cyrtodactylus are a speciose group in Southeast Asia, with at least nine species known from the island of Borneo (Das & Ismail, 2001; Das, 2006). Of these species, Cyrtodactylus cavernicolus has the smallest known range and is therefore the most vulnerable, a status that is reflected in the species having been designated a Totally Protected Species in Sarawak. Confirmed records of C. cavernicolus are known only from Niah Cave, located in an isolated limestone block known as the Gunung Subis massif, approximately 13 km² in extent. The Niah Cave Gecko is presumed to be dependent on …

Santa Clara Magazine, Volume 51 Number 3, Winter 2009, Santa Clara University

Santa Clara Magazine

18 - EVERYTHING IS ILLUMINATED By Christine Cole. For the first time since the invention of the printing press, artists have put quill pen to paper to hand-write-in calligraphy-the Bible in its entirety. The result is a wonder to behold. And available to readers and gazers at Santa Clara.

24 - HOLD THE LINE By David McKay Wilson. At Harlem's Frederick Douglass Academy, basketball coach Pat Mangan '84 has built a legendary program by making sure his players have their priorities straight. Family first. School second. Then hoops.

28 - LESSONS IN DIPLOMACY. By Sam Scott '96. How Bob LaMonte …

Ontologies And Rules, Pascal Hitzler, Bijan Parsia

Computer Science and Engineering Faculty Publications

Ontologies and rules are two established paradigms in knowledge modelling, and play an important role for the Semantic Web. In this chapter, we present an introduction to common approaches for combining OWL ontologies and rules. In particular, we cover the Semantic Web Rules Language SWRL and Description Logic Programs DLP, and give pointers to the literature.

The Role Of Landscape Connectivity In Assembling Exotic Plant Communities: A Network Analysis, Emily S. Minor, Samantha M. Tessel, Katharina A.M. Engelhardt, Todd R. Lookingbill

Geography and the Environment Faculty Publications

Landscape fragmentation and exotic species invasions are two modern-day forces that have strong and largely irreversible effects on native diversity worldwide. The spatial arrangement of habitat fragments is critical in affecting movement of individuals through a landscape, but little is known about how invasive species respond to landscape configuration relative to native species. This information is crucial for managing the global threat of invasive species spread. Using network analysis and partial Mantel tests to control for covarying environmental conditions, we show that forest plant communities in a fragmented landscape have spatial structure that is best captured by a network representation …

User-Generated Content On Social Media Challenges, Opportunities, Meenakshi Nagarajan

Kno.e.sis Publications

Understanding and exploiting user generated (textual) content (UGC) on social media is at the forefront of information management challenges today. The variety of UGC in detailed blog commentaries, collaborative wiki-content, online conversations, short messages in micro-blogs etc., are powering several personalization, monetization, crowd/business intelligence applications, and also providing an electronic microscope on social phenomena at an extraordinary scale. Certain characteristics of UGC however, necessitate key computational linguistic interventions before systems can tap into this data. A large portion of language found on social media is in the Informal English domain a blend of abbreviations, slang and context dependent terms delivered …

Long Daily Movements Of Wolves, Canis Lupus, During Pup Rearing, L. David Mech, H. Dean Cluff

United States Geological Survey, Northern Prairie Wildlife Research Center: Publications

Wolves, Canis lupus, on Ellesmere Island traveled a daily round-trip distance of 40.2 km from their den to a landfill during July 2008, plus an undetermined distance hunting after leaving the landfill. Although long travels by Wolves are well known, this appears to be the first documentation of long daily movements by Wolves rearing pups.

Iowa Academy Of Science: The New Bulletin, V05n4, Winter 2009, Iowa Academy Of Science

New Bulletin

Inside This Issue:

--Message from the Executive Director

--President's Message: Each One, Reach One

--122nd Annual Meeting

--Images from the 2009 ISTS Fall Conference

--Excellence in Science Teaching Awards (ESTA)

--Distinguished Science Awards

--IJAS Silent Auction

--Announcements, Events & Deadlines

--IAS Corporate Memberships

Life-Centered Ethics And The Human Future In Space, Michael Noah Mautner

Chemistry Publications

In the future, human destiny may depend on our ethics. In particular, biotechnology and expansion in space can transform life, raising profound questions. Guidance may be found in Life-centered ethics, as biotic ethics that value the basic patterns of organic gene/protein life, and as panbiotic ethics that always seek to expand life. These life-centered principles can be based on scientific insights into the unique place of life in nature, and the biological unity of all life. Belonging to life then implies a human purpose: to safeguard and propagate life. Expansion in space will advance this purpose but will also raise …

An Inventory And Condition Survey Of The Lower Murchison River Area, Western Australia, P Hennig

Technical Bulletins

The inventory and condition survey of the lower Murchison River area, undertaken by the Department of Agriculture and Food, Western Australia (DAFWA) between 2002 and 2003, describes and maps the natural resources of the region’s pastoral leasehold land. This survey report provides a baseline record of the existence and condition of the natural area’s resources, to assist with the planning and implementation of land management practices. The report identified and described the condition of soils, landforms, vegetation, habitat, ecosystems, and declared plants and animals. It also assessed the impact of pastoralism and made land management recommendations. This survey report presents …

Citizen Sensing, Social Signals, And Enriching Human Experience, Amit P. Sheth

Kno.e.sis Publications

In this article, I introduce the exciting paradigm of citizen sensing enabled by mobile sensors and human computing - that is, humans as citizens on the ubiquitous Web, acting as sensors and sharing their observations and views using mobile devices and Web 2.0 services.

A Psychobiological Framework Of The Substrates That Mediate Nicotine Use During Adolescence, Laura O'Dell

Selected Works Temporary Series

No abstract provided.

Alcohol Self-Administration Acutely Stimulates The Hypothalamic-Pituitary-Adrenal (Hpa) Axis, But Alcohol Dependence Leads To A Dampened Neuroendocrine State, Laura O'Dell

Selected Works Temporary Series

No abstract provided.

Female Rats Display Dose-Dependent Differences To The Rewarding And Aversive Effects Of Nicotine In An Age-, Hormone-, And Sex-Dependent Manner., Laura O'Dell

Selected Works Temporary Series

No abstract provided.

Pdf Of All O'Dell Manuscripts, Laura O'Dell

Selected Works Temporary Series

No abstract provided.

Impact Of Serotonin 2c Receptor Null Mutation On Physiology And Behavior Associated With Nigrostriatal Dopamine Pathway Function., Laura O'Dell

Selected Works Temporary Series

No abstract provided.

Rodent Models Of Nicotine Reward: What Do They Tell Us About Tobacco Abuse In Humans?, Laura O'Dell

Selected Works Temporary Series

No abstract provided.

Nicotine Withdrawal Produces Fewer Decreases In Extracellular Levels Of Dopamine In The Nucleus Accumbens Of Adolescent Versus Adult Rats., Laura O'Dell

Selected Works Temporary Series

No abstract provided.

Protracted Withdrawal From Alcohol And Drugs Of Abuse Impairs Long-Term Potentiation Of Intrinsic Excitability In The Juxtacapsular Bed Nucleus Of The Stria Terminalis, Laura O'Dell

Selected Works Temporary Series

No abstract provided.

The Effects Of Opioids And Opioid Analogs On Animal And Human Endocrine Systems, Laura O'Dell

Selected Works Temporary Series

No abstract provided.