Other Statistics and Probability Commons^™

Detecting Discordance Enrichment Among A Series Of Two-Sample Genome-Wide Expression Data Sets, Yinglei Lai, Fanni Zhang, Tapan Nayak, Reza Modarres, Norman H. Lee, Timothy A. Mccaffrey

Epidemiology Faculty Publications

Background

With the current microarray and RNA-seq technologies, two-sample genome-wide expression data have been widely collected in biological and medical studies. The related differential expression analysis and gene set enrichment analysis have been frequently conducted. Integrative analysis can be conducted when multiple data sets are available. In practice, discordant molecular behaviors among a series of data sets can be of biological and clinical interest.

Methods

In this study, a statistical method is proposed for detecting discordance gene set enrichment. Our method is based on a two-level multivariate normal mixture model. It is statistically efficient with linearly increased parameter space when …

Preparedness Of Hospitals In The Republic Of Ireland For An Influenza Pandemic, An Infection Control Perspective, Mary Reidy, Fiona Ryan, Dervla Hogan, Seán Lacey, Claire Buckley

Department of Mathematics Publications

When an influenza pandemic occurs most of the population is susceptible and attack rates can range as high as 40–50 %. The most important failure in pandemic planning is the lack of standards or guidelines regarding what it means to be ‘prepared’. The aim of this study was to assess the preparedness of acute hospitals in the Republic of Ireland for an influenza pandemic from an infection control perspective.

Meta-Analysis Of Social-Personality Psychological Research, Blair T. Johnson, Alice H. Eagly

CHIP Documents

This publication provides a contemporary treatment of the subject of meta-analysis in relation to social-personality psychology. Meta-analysis literally refers to the statistical pooling of the results of independent studies on a given subject, although in practice it refers as well to other steps of research synthesis, including defining the question under investigation, gathering all available research reports, coding of information about the studies and their effects, and interpretation/dissemination of results. Discussed as well are the hallmarks of high-quality meta-analyses.

Depicting Estimates Using The Intercept In Meta-Regression Models: The Moving Constant Technique, Blair T. Johnson Dr., Tania B. Huedo-Medina Dr.

CHIP Documents

In any scientific discipline, the ability to portray research patterns graphically often aids greatly in interpreting a phenomenon. In part to depict phenomena, the statistics and capabilities of meta-analytic models have grown increasingly sophisticated. Accordingly, this article details how to move the constant in weighted meta-analysis regression models (viz. “meta-regression”) to illuminate the patterns in such models across a range of complexities. Although it is commonly ignored in practice, the constant (or intercept) in such models can be indispensible when it is not relegated to its usual static role. The moving constant technique makes possible estimates and confidence intervals at …

Determinants Of Health Care Use Among Rural, Low-Income Mothers And Children: A Simultaneous Systems Approach To Negative Binomial Regression Modeling, Swetha Valluri

Masters Theses 1911 - February 2014

The determinants of health care use among rural, low-income mothers and their children were assessed using a multi-state, longitudinal data set, Rural Families Speak. The results indicate that rural mothers’ decisions regarding health care utilization for themselves and for their child can be best modeled using a simultaneous systems approach to negative binomial regression. Mothers’ visits to a health care provider increased with higher self-assessed depression scores, increased number of child’s doctor visits, greater numbers of total children in the household, greater numbers of chronic conditions, need for prenatal or post-partum care, development of a new medical condition, and …

Cross-Modal Enhancement Of Perceived Brightness: Sensory Interaction Versus Response Bias, Yoav Arieh, Lawrence E. Marks, Eric C. Odgaard

Department of Psychology Faculty Scholarship and Creative Works

Stein, London, Wilkinson, and Price (1996) reported the presence of cross-modal enhancement of perceived visual intensity: Participants tended to rate weak lights as brighter when accompanied by a concurrent pulse of white noise than when presented alone. In the present study, two methods were used to determine whether the enhancement reflects an early-stage sensory process or a later-stage decisional process, such as a response bias. First, the enhancement was eliminated when the noise accompanied the light on only 25% versus 50% of the trials. Second, the enhancement was absent when tested with a paired-comparison method. These findings are consistent with …

Dickey-Lincoln School Lakes Project Environmental Impact Statement: Appendix E: Aquatic Ecosystem And Fisheries Studies, Christoipher J. Schmitt, James R. Beltz, Normandeau Associates, Inc., New England Division, United States Army Engineer Division

Dickey-Lincoln School Lakes Project

Throughout this report, the following naming conventions will be used: the study area is the region of the Saint John River from Fort Kent to Ninemile Bridge and the drainage areas of all Saint John tributaries between Lincoln School and Ninemile Bridge within the United States, excluding the Allagash River drainage; the Dickey Lake Area is that region which would be inundated by the proposed Dickey Dam and the drainage areas of all rivers and streams (excluding the Saint John River) flowing into that proposed reservoir; the Lincoln School Reservoir area is that region which would be inundated by the …

Dickey-Lincoln School Lakes Project Environmental Impact Statement: Appendix H: Noise Impact Assessment, Stone & Webster Engineering Corporation, New England Division, United States Army Engineer Division

Dickey-Lincoln School Lakes Project

The overall project area can be described as a very quiet natural area remote from any major industrial activity, but subject to high traffic noise levels along the main road. Noise sensitive areas consist of low density residential areas in the villages and widely spaced residences along the main road. The estimated yearly average Ldn for all noise sensitive areas 1s 60 dB due to the close proximity of traffic to all residences. The yearly average Ldn decreases to 40 dB at 600 ft from the main road, and to 30 dB 1n the timberland areas.