Other Statistics and Probability Commons^™

Impact Of Loss To Follow-Up And Time Parameterization In Multiple-Period Cluster Randomized Trials And Assessing The Association Between Institution Affiliation And Journal Publication, Jonathan Moyer

Doctoral Dissertations

Difference-in-difference cluster randomized trials (CRTs) use baseline and post-test measurements. Standard power equations for these trials assume no loss to follow-up. We present a general equation for calculating treatment effect variance in difference-in-difference CRTs, with special cases assuming loss to follow-up with replacement of lost participants and loss to follow-up with no replacement but retaining the baseline measurements of all participants. Multiple-period CRTs can represent time as continuous using random coefficients (RC) or categorical using repeated measures ANOVA (RM-ANOVA) analytic models. Previous work recommends the use of RC over RM-ANOVA for CRTs with more than two periods because RC exhibited …