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Design And Optimization Of Four-Dimensional Cone-Beam Computed Tomography In Image-Guided Radiation Therapy, Moiz Ahmad
Design And Optimization Of Four-Dimensional Cone-Beam Computed Tomography In Image-Guided Radiation Therapy, Moiz Ahmad
Dissertations & Theses (Open Access)
The influence of respiratory motion on patient anatomy poses a challenge to accurate radiation therapy, especially in lung cancer treatment. Modern radiation therapy planning uses models of tumor respiratory motion to account for target motion in targeting. The tumor motion model can be verified on a per-treatment session basis with four-dimensional cone-beam computed tomography (4D-CBCT), which acquires an image set of the dynamic target throughout the respiratory cycle during the therapy session. 4D-CBCT is undersampled if the scan time is too short. However, short scan time is desirable in clinical practice to reduce patient setup time. This dissertation presents the …