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Dimension Reduction Techniques For High Dimensional And Ultra-High Dimensional Data, Subha Datta Dec 2019

Dimension Reduction Techniques For High Dimensional And Ultra-High Dimensional Data, Subha Datta

Dissertations

This dissertation introduces two statistical techniques to tackle high-dimensional data, which is very commonplace nowadays. It consists of two topics which are inter-related by a common link, dimension reduction.

The first topic is a recently introduced classification technique, the weighted principal support vector machine (WPSVM), which is incorporated into a spatial point process framework. The WPSVM possesses an additional parameter, a weight parameter, besides the regularization parameter. Most statistical techniques, including WPSVM, have an inherent assumption of independence, which means the data points are not connected with each other in any manner. But spatial data violates this assumption. Correlation between …


Amyloid Proteins And Fibrils Stability, Farbod Mahmoudinobar Dec 2019

Amyloid Proteins And Fibrils Stability, Farbod Mahmoudinobar

Dissertations

Compared to globular proteins that have a stable native structure, intrinsically disordered peptides (IDP) sample an ensemble of structures without folding into a native conformation.One example of IDP is the amyloid-beta(Abeta) protein which is the main constituent of senile plaques in the brain of Alzheimer's patients.Understanding the process by which IDPs undergo structural changes to form oligomers that eventually aggregate into senile plaques/amyloid fibrils may significantly advance the development of novel therapeutic methods to treat neurodegenerative diseases, for which there is no cure to date. This dissertation has two main objectives. The first one is to investigate and identify structural …


Simultaneous X-Ray Emission Accompanying Two Electron Capture For Fluorine On Gas Targets, David S. La Mantia Dec 2019

Simultaneous X-Ray Emission Accompanying Two Electron Capture For Fluorine On Gas Targets, David S. La Mantia

Dissertations

The collision between a charged ion and an atom resulting in the capture of two electrons, simultaneous with the emission of a single photon is referred to as radiative double electron capture (RDEC). For ion-atom collisions, this process can be considered the inverse of double photoionization. The study of either process, where just two electrons are involved without influence from neighboring electrons, promises new insight into electron correlation and the role it plays in quantum mechanics. Such a study for photoionization has not yet been done experimentally for two-electron ions because the only target system for which two electrons are …


Embedded Silver Nanoparticles For Metal Enhanced Photoluminescence, Shahid Iqbal Dec 2019

Embedded Silver Nanoparticles For Metal Enhanced Photoluminescence, Shahid Iqbal

Dissertations

Imaging of biologically significant molecules using plasmons of Metal Nanoparticles (MNPs) is gaining attention in the research community. Localized Surface Plasmon Resonance (LSPR) is the coherent oscillation of conduction electrons of MNPs. The biologically significant molecule is labeled with the fluorophore molecule to get the image. This approach is widely used in clinical practices, however, low intensity light emission from the labeled molecule makes it difficult to image the biologically significant material. One way to improve the weak intensities of fluorophore is to enhance the brightness using a process called Metal Enhanced Photoluminescence (MEP). This phenomenon occurs in the close …


A Computational Study Of Sleep And The Hemispheres Of The Brain, Tera Ashley Glaze Oct 2019

A Computational Study Of Sleep And The Hemispheres Of The Brain, Tera Ashley Glaze

Dissertations

Sleep and sleep cycles have been studied for over a century, and scientists have worked on modeling sleep for nearly as long as computers have existed. Despite this extensive study, sleep still holds many mysteries. Larger and more extensive sleep-wake models have been developed, and the circadian drive has been depicted in numerous fashions, as well as incorporated into scores of studies. With the ever-growing knowledge of sleep comes the need to find more ways to examine, quantify, and define it in the context of the most complex part of the human anatomy – the brain. Presented here is the …


Morphological Study Of Voids In Ultra-Large Models Of Amorphous Silicon, Durga Prasad Paudel Aug 2019

Morphological Study Of Voids In Ultra-Large Models Of Amorphous Silicon, Durga Prasad Paudel

Dissertations

The microstructure of voids in pure and hydrogen-rich amorphous silicon (a:Si) network was studied in ultra-large models of amorphous silicon, using classical and quantum- mechanical simulations, on the nanometer length scale. The nanostructure, particularly voids of device grade ultra-large models of a:Si was studied, in which observed three-dimensional realistic voids were extended using geometrical approach within the experimental limit of void-volume fractions. In device-grade simulated models, the effect of void morphology; size, shape, number density, and distribution on simulated scattering intensities in small- angle region were investigated. The evolution of voids on annealing below the crystallization temperature …


Investigation Of Structural, Optical And Electronic Properties Of Modified Methylammonium Lead Iodide Perovskites, Rasanjali Jayathissa Aug 2019

Investigation Of Structural, Optical And Electronic Properties Of Modified Methylammonium Lead Iodide Perovskites, Rasanjali Jayathissa

Dissertations

Owing to their high-power conversion efficiency (PCE), easy processability, and low fabrication cost, organic lead halide perovskites (OLHP) are emerging as a most promising photovoltaic technology. However, toxicity of lead (Pb) is a major concern for further development. Therefore, it is essential to explore nontoxic metals to replace lead in these materials. In the current research work, nontoxic Mn2+, Na+ and Ba2+ are doped at 1, 5 and 10% mole concentrations to partially substitute Pb2+ in methyl ammonium lead iodide (CH3NH3PbI3 or MAPbI3) perovskite systems, and the effects …


Sensitivity Of The Theoretical Electron Capture Shape And Comparisons To Experiment, Katrina E. Koehler Jun 2019

Sensitivity Of The Theoretical Electron Capture Shape And Comparisons To Experiment, Katrina E. Koehler

Dissertations

The direct neutrino mass is a fundamental physics quantity with far-reaching implications for the physics community. Current experimental limits put the direct neutrino mass at less than 2 eV. The neutrino mass can be explored through an end-point measurement of tritium beta decay, which is currently underway in the KArlsruhe TRItium Neutrino experiment (KATRIN). KATRIN has a lower limit of 0.2 eV, at which point there will be either a mass measurement or another upper bound. In either case, an alternative experiment with different systematics is needed to verify the results and/or push the upper bound lower. The end point …


Multi-Wavelength Investigation Of Energy Release And Chromospheric Evaporation In Solar Flares, Viacheslav M. Sadykov May 2019

Multi-Wavelength Investigation Of Energy Release And Chromospheric Evaporation In Solar Flares, Viacheslav M. Sadykov

Dissertations

For a comprehensive understanding of the energy release and chromospheric evaporation processes in solar flares it is necessary to perform a combined multi-wavelength analysis using observations from space-based and ground-based observatories, and compare the results with predictions of the radiative hydrodynamic (RHD) flare models. Initially, the case study of spatially-resolved chromospheric evaporation properties for an M 1.0-class solar flare (SOL2014-06-12T21:12) using data form IRIS (Interface Region Imaging Spectrograph), HMI/SDO (Helioseismic and Magnetic Imager onboard Solar Dynamics Observatory), and VIS/GST (Visible Imaging Spectrometer at Goode Solar Telescope), demonstrate a complicated nature of evaporation and its connection to the magnetic field topology. …


Rare Event Sampling In Applied Stochastic Dynamical Systems, Yiming Yu May 2019

Rare Event Sampling In Applied Stochastic Dynamical Systems, Yiming Yu

Dissertations

Predicting rare events is a challenging problem in many complex systems arising in physics, chemistry, biology, and materials science. Simulating rare events is often prohibitive in such systems due to their high dimensionality and the numerical cost of their simulation, yet analytical expressions for rare event probabilities are usually not available. This dissertation tackles the problem of approximation of the probability of rare catastrophic events in optical communication systems and spin-torque magnetic nanodevices. With the application of the geometric minimum action method, the probability of pulse position shifts or other parameter changes in a model of an actively mode-locked laser …


High Resolution Near-Infrared/Visible Intracavity Laser Spectroscopy Of Small Molecules, Jack Harms Apr 2019

High Resolution Near-Infrared/Visible Intracavity Laser Spectroscopy Of Small Molecules, Jack Harms

Dissertations

Intracavity laser spectroscopy has been used to study the electronic structure of several small molecules. The molecules studied as part of this dissertation include germanium hydride (GeH), copper oxide (CuO), nickel chloride (NiCl), platinum fluoride (PtF), platinum chloride (PtCl), and copper hydroxide (CuOH). This work encompasses five peer-reviewed publications and two submitted manuscripts.


Sources And Atmospheric Oxidation Of Sulfur Dioxide And Formaldehyde Based On Wintertime Aircraft Observations Over The Eastern United States, Jaime R. Green Jan 2019

Sources And Atmospheric Oxidation Of Sulfur Dioxide And Formaldehyde Based On Wintertime Aircraft Observations Over The Eastern United States, Jaime R. Green

Dissertations

Plume intercepts from flights on the NSF-C-130 during the Wintertime Investigation of Transport, Emission and Reactivity (WINTER) campaign were used to estimate (1) the oxidation rates of Sulfur Dioxide (SO2) under wintertime conditions and the factors that determine SO2 removal; and (2) to examine the oxidation, lifetime and source apportionment of formaldehyde (HCHO). Observations suggest that OH governs the rate SO2 oxidation in the eastern United States during winter. The range of mean oxidation rates during the day from power plants were 0.22–0.71%/hr, producing SO2 lifetimes of 13–43 days, if SO2 consumption is assumed to occur during 10.5 hr of …