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Pinning The Conformation Of A Protein (Cora) In A Solute Matrix With Selective Binding, Warin Rangubpit, Sunan Kitjaruwankul, Pornthep Sompornpisut, R. B. Pandey
Pinning The Conformation Of A Protein (Cora) In A Solute Matrix With Selective Binding, Warin Rangubpit, Sunan Kitjaruwankul, Pornthep Sompornpisut, R. B. Pandey
Faculty Publications
Conformation of a protein (CorA) is examined in a matrix with mobile solute constituents as a function of solute–residue interaction strength (f) by a coarse-grained model with a Monte Carlo simulation. Solute particles are found to reach their targeted residue due to their unique interactions with the residues. Degree of slowing down of the protein depends on the interaction strength f. Unlike a predictable dependence of the radius of gyration of the same protein on interaction in an effective medium, it does not show a systematic dependence on interaction due to pinning caused by the solute binding. …