Physics Commons^™

The Interaction Between A Thiol Specific Probe (Opa) And The Single Channel Characteristics Of The Reconstituted Ca++ Release Protein From Skeletal Muscle Sarcoplasmic Reticulum, Alexander Braun

Dissertations and Theses

One advantage of higher life-forms over less developed organisms is their ability to respond to signals from their environment with motion. This requires highly specialized contractile cells and a whole locomotion apparatus. In vertebrates, the cells responsible for movement are the skeletal muscle cells. They receive signals from the autonomic nervous system in the form of an action potential, and they contract in an appropriate manner. Calcium is a vital intracellular passenger whose role in muscular function is to initiate contraction. It is released via specific channel proteins from an internal Ca++ store, the sarcoplasmic reticulum, and triggers muscular contraction, …